BR9712971A - Método para produção de uma vacina para proteção de um hospedeiro contra doença causada com uma cadeia de chlamydia e composição imunológica - Google Patents
Método para produção de uma vacina para proteção de um hospedeiro contra doença causada com uma cadeia de chlamydia e composição imunológicaInfo
- Publication number
- BR9712971A BR9712971A BR9712971-2A BR9712971A BR9712971A BR 9712971 A BR9712971 A BR 9712971A BR 9712971 A BR9712971 A BR 9712971A BR 9712971 A BR9712971 A BR 9712971A
- Authority
- BR
- Brazil
- Prior art keywords
- momp
- chlamydia
- host
- vaccine
- protect
- Prior art date
Links
- 241000606161 Chlamydia Species 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000001900 immune effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 101710164702 Major outer membrane protein Proteins 0.000 abstract 5
- 101710105759 Major outer membrane porin Proteins 0.000 abstract 4
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- -1 DNA Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 230000003362 replicative effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"MéTODO PARA PRODUçãO DE UMA VACINA PARA PROTEçãO DE UM HOSPEDEIRO CONTRA DOENçA CAUSADA COM UMA CADEIA DE CHLAMYDIA E COMPOSIçãO IMUNOLóGICA". ácido nucléico, incluindo DNA, imunização para gerar um replicante imune para proteção em um hospedeiro, incluindo seres humanos, para uma proteína de membrana externa principal de uma cadeia de Chlamydia, preferivelmente uma seq³ência de nucleotídeos codificando um MOMP ou fragmento de MOMP que gera anticorpos que especialmente reagem com MOMP e uma seq³ência operacionalmente acoplada a primeira seq³ência para expressão do MOMP no hospedeiro. O vetor não replicante pode ser formulado com um carreador farmaceuticamente aceitável para administração "in vivo" no hospedeiro.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2160796P | 1996-07-12 | 1996-07-12 | |
| PCT/CA1997/000500 WO1998002546A2 (en) | 1996-07-12 | 1997-07-11 | Dna immunization against chlamydia infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9712971A true BR9712971A (pt) | 2002-05-07 |
Family
ID=21805154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9712971-2A BR9712971A (pt) | 1996-07-12 | 1997-07-11 | Método para produção de uma vacina para proteção de um hospedeiro contra doença causada com uma cadeia de chlamydia e composição imunológica |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0915978B1 (pt) |
| JP (1) | JP2000503325A (pt) |
| AT (1) | ATE312920T1 (pt) |
| AU (1) | AU723235B2 (pt) |
| BR (1) | BR9712971A (pt) |
| CA (1) | CA2259595C (pt) |
| DE (1) | DE69734882T2 (pt) |
| NZ (1) | NZ334114A (pt) |
| WO (1) | WO1998002546A2 (pt) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6696421B2 (en) | 1996-07-12 | 2004-02-24 | University Of Manitoba | DNA immunization against chlamydia infection |
| US6344202B1 (en) * | 1996-07-12 | 2002-02-05 | University Of Manitoba | DNA immunization against chlaymdia infection |
| US6838552B1 (en) | 1997-08-14 | 2005-01-04 | Vanderbilt University | Diagnosis and management of infection caused by Chlamydia |
| US6340463B1 (en) | 1996-08-14 | 2002-01-22 | Vanderbilt University | Identification of antigenic peptide sequences |
| WO2000006739A2 (en) * | 1998-07-27 | 2000-02-10 | Connaught Laboratories Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US20030147924A1 (en) * | 1998-07-27 | 2003-08-07 | Aventis Pasteur Limited/Aventis Pasteur Limitee | Chlamydia antigens and corresponding dna fragments and uses thereof |
| AU4793499A (en) * | 1998-07-27 | 2000-02-21 | Aventis Pasteur Limited | (chlamydia) antigens and corresponding dna fragments and uses thereof |
| US6693087B1 (en) | 1998-08-20 | 2004-02-17 | Aventis Pasteur Limited | Nucleic acid molecules encoding POMP91A protein of Chlamydia |
| EP1105489A1 (en) * | 1998-08-20 | 2001-06-13 | Aventis Pasteur Limited | Nucleic acid molecules encoding pomp91a protein of chlamydia |
| US6649370B1 (en) * | 1998-10-28 | 2003-11-18 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6403101B1 (en) * | 1998-10-28 | 2002-06-11 | Connaught Laboratories Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6403102B1 (en) * | 1998-10-29 | 2002-06-11 | Connaught Laboratories Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| WO2000032784A1 (en) * | 1998-12-01 | 2000-06-08 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| MXPA01005615A (es) | 1998-12-04 | 2004-08-19 | Univ Manitoba | Procedimiento de inmunizacion en dos pasos para proteger contra infeccion por chlamydia. |
| US6447779B1 (en) | 1998-12-08 | 2002-09-10 | Corixa Corporation | Compounds for the diagnosis of Chlamydial infection |
| US6448234B1 (en) | 1998-12-08 | 2002-09-10 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US6432916B1 (en) | 1998-12-08 | 2002-08-13 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| TR200102500T2 (tr) * | 1998-12-08 | 2002-03-21 | Corixa Corporation | Chlamydia enfeksiyonunu tedavi etmek iin bileçikler. |
| US6565856B1 (en) | 1998-12-08 | 2003-05-20 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20020061848A1 (en) | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US6555115B1 (en) | 1998-12-08 | 2003-04-29 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US6808713B1 (en) | 1998-12-28 | 2004-10-26 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| WO2000039157A1 (en) * | 1998-12-28 | 2000-07-06 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| JP2002542814A (ja) * | 1999-05-01 | 2002-12-17 | ジェネーラ コーポレーション | 喘息および関連する障害を含むアトピー性のアレルギーを処置するための標的としての喘息に関連する因子 |
| US6811783B1 (en) | 1999-09-07 | 2004-11-02 | Aventis Pasteur Limited | Immunogenic compositions for protection against chlamydial infection |
| EP1220925B8 (en) | 1999-09-20 | 2008-04-23 | Sanofi Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US6632663B1 (en) | 1999-09-22 | 2003-10-14 | Aventis Pasteur Limited | DNA immunization against chlamydia infection |
| WO2001046226A2 (en) * | 1999-12-22 | 2001-06-28 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| AU2138501A (en) * | 1999-12-22 | 2001-07-03 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| JP4864264B2 (ja) * | 1999-12-22 | 2012-02-01 | サノフィ、パストゥール、リミテッド | クラミジア抗原および対応するdna断片ならびにその使用 |
| US20010048927A1 (en) | 2000-02-01 | 2001-12-06 | Richard Stephens | Porin B (PorB) as a therapeutic target for prevention and treatment of infection by chlamydia |
| ES2303525T3 (es) | 2000-04-21 | 2008-08-16 | Corixa Corporation | Compuestos y metodos para el tratamiento y diagnostico de infeccion por chlamydia. |
| US6919187B2 (en) | 2000-04-21 | 2005-07-19 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US7105171B2 (en) | 2002-03-07 | 2006-09-12 | The Regents Of The University Of California | Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia |
| EP2576602B1 (en) | 2010-05-28 | 2020-02-12 | Spixia Biotechnology AB | Chimeric momp antigen, method and use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE143414T1 (de) * | 1985-01-14 | 1996-10-15 | Chiron Corp | Hauptprotein der aussenmembran von chlamydia |
-
1997
- 1997-07-11 NZ NZ334114A patent/NZ334114A/en not_active IP Right Cessation
- 1997-07-11 CA CA2259595A patent/CA2259595C/en not_active Expired - Fee Related
- 1997-07-11 AT AT97930277T patent/ATE312920T1/de not_active IP Right Cessation
- 1997-07-11 DE DE69734882T patent/DE69734882T2/de not_active Expired - Lifetime
- 1997-07-11 JP JP10505478A patent/JP2000503325A/ja not_active Ceased
- 1997-07-11 WO PCT/CA1997/000500 patent/WO1998002546A2/en not_active Ceased
- 1997-07-11 AU AU34314/97A patent/AU723235B2/en not_active Ceased
- 1997-07-11 BR BR9712971-2A patent/BR9712971A/pt active Search and Examination
- 1997-07-11 EP EP97930277A patent/EP0915978B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2259595C (en) | 2010-11-30 |
| WO1998002546A3 (en) | 1998-02-26 |
| EP0915978B1 (en) | 2005-12-14 |
| NZ334114A (en) | 2000-06-23 |
| DE69734882D1 (de) | 2006-01-19 |
| ATE312920T1 (de) | 2005-12-15 |
| EP0915978A2 (en) | 1999-05-19 |
| CA2259595A1 (en) | 1998-01-22 |
| JP2000503325A (ja) | 2000-03-21 |
| WO1998002546A2 (en) | 1998-01-22 |
| AU3431497A (en) | 1998-02-09 |
| DE69734882T2 (de) | 2006-08-17 |
| AU723235B2 (en) | 2000-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ART 37, SUGIRO O INDEFERIMENTO DO PRESENTE PEDIDO, TENDO POR BASE OS ARTIGOS 8O, 13, 24 E 25 DA LEI 9.279 DE 14/05/1996. |
|
| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 17A ANUIDADE |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2291 DE 02/12/2014. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |