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BR9712628A - Derivatives of 8 (9) -dehydroestradiol - Google Patents

Derivatives of 8 (9) -dehydroestradiol

Info

Publication number
BR9712628A
BR9712628A BR9712628-4A BR9712628A BR9712628A BR 9712628 A BR9712628 A BR 9712628A BR 9712628 A BR9712628 A BR 9712628A BR 9712628 A BR9712628 A BR 9712628A
Authority
BR
Brazil
Prior art keywords
dehydroestradiol
derivatives
pharmaceutically acceptable
acceptable salt
sulfate ester
Prior art date
Application number
BR9712628-4A
Other languages
Portuguese (pt)
Inventor
Steven Jay Adelman
Frederick James Bex
Appavu Chandrasekaran
Dorothy Helen Prozialeck
Michael William Winkley
Panolil Raveendranath
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of BR9712628A publication Critical patent/BR9712628A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção:<B>"DERIVADOS DE 8(9)-DEIDROESTRADIOL"<D>. A presente invenção proporciona 17<244>,<30>8,9-deidroestradiol ou um sal farmaceuticamente aceitável de seu éster de 3-sulfato e 17<225>,<30>8,9-deidroestradiol ou um sal farmaceuticamente aceitável de seu éster de 3-sulfato.Invention Patent: <B> "DERIVATIVES OF 8 (9) -DEHYDROestradiol" <D>. The present invention provides 17 <244>, <30> 8,9-dehydroestradiol or a pharmaceutically acceptable salt of its 3-sulfate ester and 17 <225>, <30> 8,9-dehydroestradiol or a pharmaceutically acceptable salt of its 3-sulfate ester.

BR9712628-4A 1996-10-11 1997-10-09 Derivatives of 8 (9) -dehydroestradiol BR9712628A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2793696P 1996-10-11 1996-10-11
PCT/US1997/018306 WO1998016544A1 (en) 1996-10-11 1997-10-09 8(9)-dehydroestradiol derivatives

Publications (1)

Publication Number Publication Date
BR9712628A true BR9712628A (en) 1999-10-26

Family

ID=21840614

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9712628-4A BR9712628A (en) 1996-10-11 1997-10-09 Derivatives of 8 (9) -dehydroestradiol

Country Status (13)

Country Link
EP (1) EP0934334A1 (en)
JP (1) JP2001502328A (en)
KR (1) KR20000049055A (en)
CN (1) CN1239967A (en)
AR (1) AR014096A1 (en)
AU (1) AU743530B2 (en)
BR (1) BR9712628A (en)
CA (1) CA2268330A1 (en)
HU (1) HUP9903369A3 (en)
IL (1) IL129029A0 (en)
NZ (1) NZ335183A (en)
WO (1) WO1998016544A1 (en)
ZA (1) ZA979069B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1368037A2 (en) * 2001-03-16 2003-12-10 Wyeth Estrogen replacement therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES341947A1 (en) * 1966-06-21 1968-08-01 American Home Prod A procedure for preparing steroid compounds. (Machine-translation by Google Translate, not legally binding)
SU286675A1 (en) * 1969-01-10 1973-08-10 Институт химии природных соединений СССР WAY OF OBTAINING dl-ESTRADIOLAYSS-UNION fi ^ iffiTau - ::: X:.: F-lAfi LIBRARY
FR2136891A1 (en) * 1971-05-07 1972-12-29 Inst Khim Prirodny Racemic estra-3,17 beta-diol prepn - steroid hormones
US5210081A (en) * 1992-02-26 1993-05-11 American Home Products Corporation Alkali metal 8,9-dehydroestrone sulfate esters
DE4338314C1 (en) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmaceutical preparations for the prophylaxis and therapy of radical-mediated cell damage

Also Published As

Publication number Publication date
HUP9903369A2 (en) 2001-06-28
IL129029A0 (en) 2000-02-17
HUP9903369A3 (en) 2002-02-28
WO1998016544A1 (en) 1998-04-23
AU743530B2 (en) 2002-01-31
CA2268330A1 (en) 1998-04-23
JP2001502328A (en) 2001-02-20
NZ335183A (en) 2000-09-29
AR014096A1 (en) 2001-02-07
KR20000049055A (en) 2000-07-25
EP0934334A1 (en) 1999-08-11
ZA979069B (en) 1999-04-09
AU5145998A (en) 1998-05-11
CN1239967A (en) 1999-12-29

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: WYETH (US)

Free format text: ALTERADO DE: AMERICAN HOME PRODUCTS CORPORATION

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1832 DE 14/02/2006.