[go: up one dir, main page]

BR9711998A - Herpesvìrus saimiri como vetor viral. - Google Patents

Herpesvìrus saimiri como vetor viral.

Info

Publication number
BR9711998A
BR9711998A BR9711998-9A BR9711998A BR9711998A BR 9711998 A BR9711998 A BR 9711998A BR 9711998 A BR9711998 A BR 9711998A BR 9711998 A BR9711998 A BR 9711998A
Authority
BR
Brazil
Prior art keywords
saimiri
viral vector
herpesviruses
essential
genes
Prior art date
Application number
BR9711998-9A
Other languages
English (en)
Inventor
David Mark Meredith
Original Assignee
Univ Leeds
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leeds filed Critical Univ Leeds
Publication of BR9711998A publication Critical patent/BR9711998A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16411—Rhadinovirus, e.g. human herpesvirus 8
    • C12N2710/16422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16411—Rhadinovirus, e.g. human herpesvirus 8
    • C12N2710/16441—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16443—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"HERPESVìRUS SAIMIRI COMO VETOR VIRAL". A invenção refere-se a um meio para um herpesvírus saimiri que foi geneticamente modificado mutando e/ou deletando os genes essenciais específicos e não-essenciais. Os genes essenciais são requeridos em replicação de genes virais e são necessários para proliferação viral. Os genes não-essenciais podem representar sítios para a inserção de material genético heterólogo, isto é, genes terapêuticos
BR9711998-9A 1996-09-04 1997-09-04 Herpesvìrus saimiri como vetor viral. BR9711998A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9618477.5A GB9618477D0 (en) 1996-09-04 1996-09-04 Gene therapy
PCT/GB1997/002371 WO1998010083A1 (en) 1996-09-04 1997-09-04 Herpesvirus saimiri as viral vector

Publications (1)

Publication Number Publication Date
BR9711998A true BR9711998A (pt) 2000-01-18

Family

ID=10799414

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9711998-9A BR9711998A (pt) 1996-09-04 1997-09-04 Herpesvìrus saimiri como vetor viral.

Country Status (18)

Country Link
US (1) US6379967B1 (pt)
EP (1) EP0939828B1 (pt)
JP (1) JP2000517191A (pt)
KR (1) KR20000068461A (pt)
CN (1) CN1237209A (pt)
AT (1) ATE342997T1 (pt)
AU (1) AU737197B2 (pt)
BR (1) BR9711998A (pt)
CA (1) CA2264956A1 (pt)
CZ (1) CZ69799A3 (pt)
DE (1) DE69736838T2 (pt)
ES (1) ES2274541T3 (pt)
GB (1) GB9618477D0 (pt)
HU (1) HUP9904329A3 (pt)
IL (1) IL128635A0 (pt)
NZ (1) NZ334323A (pt)
SG (1) SG91252A1 (pt)
WO (1) WO1998010083A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9826069D0 (en) * 1998-11-28 1999-01-20 Univ Leeds HIV vaccine
GB9903694D0 (en) * 1999-02-19 1999-04-14 Univ Leeds Latency-associated regulatory region
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US20040219516A1 (en) * 2002-07-18 2004-11-04 Invitrogen Corporation Viral vectors containing recombination sites
WO2005014796A2 (en) 2003-08-08 2005-02-17 Invitrogen Corporation Methods and compositions for seamless cloning of nucleic acid molecules
ATE469984T1 (de) 2003-12-01 2010-06-15 Life Technologies Corp Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon
PT1912675E (pt) 2005-07-25 2014-05-09 Emergent Product Dev Seattle Moléculas de ligaçao especificas para cd37 e especificas para cd20
US8409577B2 (en) 2006-06-12 2013-04-02 Emergent Product Development Seattle, Llc Single chain multivalent binding proteins with effector function
US20090148447A1 (en) * 2007-07-06 2009-06-11 Trubion Pharmaceuticals, Inc. Binding Peptides Having a C-terminally Disposed Specific Binding Domain
NZ603059A (en) * 2008-04-11 2014-07-25 Emergent Product Dev Seattle Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
US11352426B2 (en) 2015-09-21 2022-06-07 Aptevo Research And Development Llc CD3 binding polypeptides
US11149255B2 (en) * 2016-09-06 2021-10-19 Bioventures, Llc Compositions and methods for generating reversion free attenuated and/or replication incompetent vaccine vectors
CN107653345B (zh) * 2017-11-08 2021-04-27 中国人民解放军军事医学科学院野战输血研究所 猴b病毒实时荧光定量pcr方法及其通用引物、mgb探针与试剂盒
RU2771081C2 (ru) * 2020-08-25 2022-04-26 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Рекомбинантный штамм Herpesvirus saimiri для получения популяций иммортализованных аутологичных Т-лимфоцитов, экспрессирующих парные химерные рецепторы против опухолевых антигенов CD44 и CD133

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672344A (en) * 1987-12-30 1997-09-30 The Regents Of The University Of Michigan Viral-mediated gene transfer system
AU4408889A (en) * 1988-10-06 1990-05-01 Behringwerke Aktiengesellschaft H. saimiri-htlv-x region vector
DE3834157A1 (de) * 1988-10-07 1990-04-19 Behringwerke Ag Selektionierbare vektoren fuer humane t-zellen

Also Published As

Publication number Publication date
IL128635A0 (en) 2000-01-31
JP2000517191A (ja) 2000-12-26
HUP9904329A3 (en) 2002-01-28
ATE342997T1 (de) 2006-11-15
AU4307197A (en) 1998-03-26
CA2264956A1 (en) 1998-03-12
AU737197B2 (en) 2001-08-09
NZ334323A (en) 2000-06-23
KR20000068461A (ko) 2000-11-25
WO1998010083A1 (en) 1998-03-12
EP0939828A1 (en) 1999-09-08
HUP9904329A2 (hu) 2000-04-28
CN1237209A (zh) 1999-12-01
GB9618477D0 (en) 1996-10-16
DE69736838T2 (de) 2007-10-31
DE69736838D1 (de) 2006-11-30
CZ69799A3 (cs) 1999-08-11
SG91252A1 (en) 2002-09-17
ES2274541T3 (es) 2007-05-16
EP0939828B1 (en) 2006-10-18
US6379967B1 (en) 2002-04-30

Similar Documents

Publication Publication Date Title
BR9711998A (pt) Herpesvìrus saimiri como vetor viral.
Fåhraeus et al. Epstein-Barr virus-encoded nuclear antigen 2 activates the viral latent membrane protein promoter by modulating the activity of a negative regulatory element.
DK0863202T3 (da) Rekombinant Sendai-virus
DE69635173D1 (de) Rekombinante MVA Viren und deren Verwendung
DE69739870D1 (de) Verbesserte adenovirusvektoren
DE60121471D1 (de) Komplementierende zellinien
HUP9702377A2 (hu) Önfelerősítő, gyógyszeres úton szabályozható expressziós rendszerek
DE3471688D1 (en) Dna vectors and their use in recombinant dna technology
EP0844888A4 (en) TISSUE-SPECIFIC VIRAL VECTORS
FI973309A0 (fi) Menetelmä yhdistelmä-DNA-adenovirusgenomin valmistamiseksi
DK1021553T3 (da) Eukaryotisk genekspressionskassette og anvendelser deraf
ES8504254A1 (es) Procedimiento para obtener un polipeptido
AU5318496A (en) Adenovirus vectors for gene therapy
ATE272713T1 (de) Ehv-1 vektoren
IL148360A0 (en) A herpes viral mutant and pharmaceutical compositions containing the same
SE8604636L (sv) Sett att uttrycka gener med hjelp av bacillus brevis
DE69417717D1 (de) Impstoff zum Schutze von Pferden gegen Pferdeherpesvirus-Infektionen
HUP9902585A2 (hu) Replikálódó molekulák in vivo előállítása
ID24649A (id) Replikon virus epstein-barr kompak
Leung et al. A direct cloning-expression system for neutralization antigens of herpes simplex viruses.
BR9909288A (pt) Sequências reguladoras de fator-9 dediferenciação de crescimento e usos das mesmas
ELIA et al. Interaction of the dsRNA-dependent protein kinase PKR with Epstein-Barr virus W RNAs
BR9810643A (pt) Genes e proteìnas de telomerase de vertebrado, eutilização dos mesmos
CA2617830A1 (en) Direct molecular cloning of a modified eukaryotic cytoplasmic dna virus genome

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]