BR9710975A - Genes de proteìna de adesão de superfìcie exposta de 120 kda imunodominante de ehrlichia chaffeensis - Google Patents
Genes de proteìna de adesão de superfìcie exposta de 120 kda imunodominante de ehrlichia chaffeensisInfo
- Publication number
- BR9710975A BR9710975A BR9710975-4A BR9710975A BR9710975A BR 9710975 A BR9710975 A BR 9710975A BR 9710975 A BR9710975 A BR 9710975A BR 9710975 A BR9710975 A BR 9710975A
- Authority
- BR
- Brazil
- Prior art keywords
- kda
- exposed surface
- surface adhesion
- genes
- ehrlichia chaffeensis
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 241000605310 Ehrlichia chaffeensis Species 0.000 title abstract 4
- 206010020429 Human ehrlichiosis Diseases 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 101710181704 Antigenic heat-stable 120 kDa protein Proteins 0.000 abstract 3
- 101710173353 Cytotoxicity-associated immunodominant antigen Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/29—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Richettsiales (O)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Patente de Invenção: <B>"GENES DE PROTEìNA DE ADESãO DE SUPERFìCIE EXPOSTA DE 120 KDA IMUNODOMINANTE DE EHRLICHIA CHAFFEENSIS"<D>. é divulgado um gene isolado que codifica um antígeno imunodominante de 120 kDa de Ehrlichia chaffeensis. A proteína de 120 kDa é uma das proteínas imunodominantes de E. chaffeensis que estimula a produção de anticorpos específicos em humanos infectados. Também divulgada é a seq³ência de aminoácido do antígeno de 120 kDa. São divulgados processos de produção de um antígeno de 120 kDa recombinante e processos terapêuticos de uso do antígeno.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/656,034 US6015691A (en) | 1996-05-31 | 1996-05-31 | Immunodominant 120 kDa surface-exposed adhesion protein genes of Ehrlichia chaffeensis |
| PCT/US1997/009147 WO1997045540A1 (en) | 1996-05-31 | 1997-05-30 | Immunodominant 120 kda surface-exposed adhesion protein genes of ehrlichia chaffeensis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9710975A true BR9710975A (pt) | 2000-10-24 |
Family
ID=24631362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9710975-4A BR9710975A (pt) | 1996-05-31 | 1997-05-30 | Genes de proteìna de adesão de superfìcie exposta de 120 kda imunodominante de ehrlichia chaffeensis |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6015691A (pt) |
| AU (1) | AU3219497A (pt) |
| BR (1) | BR9710975A (pt) |
| CA (1) | CA2256532C (pt) |
| WO (1) | WO1997045540A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69841037D1 (de) | 1997-04-25 | 2009-09-17 | Antigenics Inc | Charakterisierung von granulozytischer ehrlichia und methoden für ihre verwendung. |
| EP1100917A1 (en) * | 1998-07-28 | 2001-05-23 | Aquila Biopharmaceuticals, Inc. | Granulocytic ehrlichia genes and uses thereof |
| US6043085A (en) * | 1998-08-27 | 2000-03-28 | Research Development Foundation | Ehrlichia canis 120-kDa immunodominant antigenic protein and gene |
| US20020115840A1 (en) * | 1998-11-30 | 2002-08-22 | Walker David H. | Homologous 28-kilodaltion immunodominant protein genes of Ehrlichia canis and uses thereof |
| US7407770B2 (en) * | 2001-01-18 | 2008-08-05 | Idexx Corporation | Compositions and methods for detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies |
| US7183060B2 (en) * | 2005-02-22 | 2007-02-27 | Idexx Laboratories, Inc. | Peptides for detection of antibody to Ehrlichia ewingii |
| US20030129680A1 (en) * | 2001-10-31 | 2003-07-10 | O'connor Thomas Patrick | Multi-analyte assay device |
| US7087372B2 (en) * | 2001-01-18 | 2006-08-08 | Idexx Laboratories, Inc. | Compositions and methods for detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies |
| US20030194756A1 (en) * | 2002-04-12 | 2003-10-16 | O'connor Thomas Patrick | Peptides for detection of antibody to Ehrlichia equi |
| US7507789B2 (en) * | 2007-04-09 | 2009-03-24 | Idexx Laboratories, Inc. | Detection of Anaplasma platys |
| WO2009039414A2 (en) | 2007-09-21 | 2009-03-26 | Idexx Laboratories, Inc. | Methods and compositions for detection of ehrlichia chaffeensis (vlpt) |
| BRPI0816437B8 (pt) * | 2007-09-21 | 2021-05-25 | Idexx Lab Inc | polipeptídeos purificados e métodos para a detecção de ehrlichia chaffeensis em uma amostra teste |
| WO2009070507A2 (en) | 2007-11-27 | 2009-06-04 | Idexx Laboratories, Inc. | Anaplasma phagocytophilum (aph) antigens and antibodies specific for anaplasma |
| JP6110066B2 (ja) * | 2008-10-08 | 2017-04-05 | アイデックス ラボラトリーズ インコーポレイテッドIDEXX Laboratories, Inc. | アナプラズマ・ファゴサイトフィルム(Aph)およびアナプラズマ・プラチス(Apl)に特異的な抗体を検出するための組成物および方法 |
| WO2010126993A1 (en) | 2009-04-28 | 2010-11-04 | Research Development Foundation | Immunoreactive ehrlichia p120/p140 epitopes and uses thereof |
| US9133525B2 (en) | 2012-01-26 | 2015-09-15 | Luc Montagnier | Detection of DNA sequences as risk factors for HIV infection |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ225295A (en) * | 1987-07-07 | 1991-07-26 | Biotech Australia Pty Ltd | Nematode antigen, its production and vaccines containing it |
| AU1970892A (en) * | 1991-04-18 | 1992-11-17 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Identification of a new ehrlichia species from a patient suffering from ehrlichiosis |
-
1996
- 1996-05-31 US US08/656,034 patent/US6015691A/en not_active Expired - Lifetime
-
1997
- 1997-05-30 AU AU32194/97A patent/AU3219497A/en not_active Abandoned
- 1997-05-30 BR BR9710975-4A patent/BR9710975A/pt not_active Application Discontinuation
- 1997-05-30 WO PCT/US1997/009147 patent/WO1997045540A1/en not_active Ceased
- 1997-05-30 CA CA2256532A patent/CA2256532C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2256532A1 (en) | 1997-12-04 |
| US6015691A (en) | 2000-01-18 |
| AU3219497A (en) | 1998-01-05 |
| CA2256532C (en) | 2010-02-09 |
| WO1997045540A1 (en) | 1997-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: RESEARCH DEVELOPMENT FOUNDATION (US) |
|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| HKFN | Application deemed withdrawn (deleted) | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: O PRESENTE EXAME ENTENDENDO QUE A MATERIA FOI EXAUSTIVAMENTE DISCUTIDA CONCLUI O EXAME DO PEDIDO EM QUESTAO PROFERINDO, DE ACORDO COM O ARTIGO 37, A DECISAO DO INDEFERIMENTO DA PRESENTE APLICACAO, UMA VEZ QUE A MESMA POR NAO CUMPRIR AS EXIGENCIAS FORMULADAS CONTINUA REIVINDICANDO MATERIA EM DESCAORDO COM O DISPOSTO NOS ARTIGOS 10 (IX), 25 E 32 DA LEI 9279/96. |
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| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |