[go: up one dir, main page]

BR9710735A - Processos para detec-Æo de atividade de heparanase de mamiferos em uma amostra e para purifa-Æo de heparanase de maniferos a partir de um material contendo heparanase kit para uso na detec-Æo da atividade da heparanase de mamiferos em uma amostra e heparanase de mamiferos substancialmente purificada e de plaquetas humanas - Google Patents

Processos para detec-Æo de atividade de heparanase de mamiferos em uma amostra e para purifa-Æo de heparanase de maniferos a partir de um material contendo heparanase kit para uso na detec-Æo da atividade da heparanase de mamiferos em uma amostra e heparanase de mamiferos substancialmente purificada e de plaquetas humanas

Info

Publication number
BR9710735A
BR9710735A BR9710735A BR9710735A BR9710735A BR 9710735 A BR9710735 A BR 9710735A BR 9710735 A BR9710735 A BR 9710735A BR 9710735 A BR9710735 A BR 9710735A BR 9710735 A BR9710735 A BR 9710735A
Authority
BR
Brazil
Prior art keywords
heparanase
sample
mammalian
activity
detecting
Prior art date
Application number
BR9710735A
Other languages
English (en)
Inventor
Craig Geoffrey Freeman
Christopher Richard Parish
Original Assignee
Univ Australian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPO1113A external-priority patent/AUPO111396A0/en
Priority claimed from AUPO3323A external-priority patent/AUPO332396A0/en
Application filed by Univ Australian filed Critical Univ Australian
Publication of BR9710735A publication Critical patent/BR9710735A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01031—Beta-glucuronidase (3.2.1.31)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01166—Heparanase (3.2.1.166)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BR9710735A 1996-07-18 1997-07-18 Processos para detec-Æo de atividade de heparanase de mamiferos em uma amostra e para purifa-Æo de heparanase de maniferos a partir de um material contendo heparanase kit para uso na detec-Æo da atividade da heparanase de mamiferos em uma amostra e heparanase de mamiferos substancialmente purificada e de plaquetas humanas BR9710735A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPO1113A AUPO111396A0 (en) 1996-07-18 1996-07-18 Assay for detection of heparanase activity
AUPO3323A AUPO332396A0 (en) 1996-10-30 1996-10-30 Purification of mammalian heparanase
PCT/AU1997/000452 WO1998003638A1 (en) 1996-07-18 1997-07-18 Detection of mammalian heparanase activity and purification of mammalian heparanase

Publications (1)

Publication Number Publication Date
BR9710735A true BR9710735A (pt) 1999-08-17

Family

ID=25645220

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9710735A BR9710735A (pt) 1996-07-18 1997-07-18 Processos para detec-Æo de atividade de heparanase de mamiferos em uma amostra e para purifa-Æo de heparanase de maniferos a partir de um material contendo heparanase kit para uso na detec-Æo da atividade da heparanase de mamiferos em uma amostra e heparanase de mamiferos substancialmente purificada e de plaquetas humanas

Country Status (11)

Country Link
US (2) US6207402B1 (pt)
EP (1) EP0935650A4 (pt)
JP (1) JP2000515014A (pt)
CN (1) CN1146659C (pt)
BR (1) BR9710735A (pt)
CA (1) CA2261290A1 (pt)
EA (1) EA003901B1 (pt)
IL (1) IL128101A (pt)
NZ (1) NZ333736A (pt)
TW (1) TW565614B (pt)
WO (1) WO1998003638A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9813296A (pt) 1997-10-28 2000-08-22 Univ Australian Molécula isolada de ácido nucleico, processo para identificar uma molécula de ácido nucleico codificando um polipeptìdeo de endoglucuronidase de mamìfero, vetor de expressão, peptìdeo de heparanase isolado, polipeptìdeo recombinante ou isolado, molécula de anticorpo, processo para identificar um modulador da atividade de heparanase, uso de um oligossacarìdeo sulfatado, um sulfonato ou hspg compreendendo os mesmos, processos para tratamento de uma condição fisiológica ou médica em um sujeito humano ou animal em que a atividade de heparanase no referido sujeito é elevada, para intensificar a cura de feridas em um sujeito humano ou animal e para diagnosticar uma condição fisiológica ou médica associada com a super-expressão de heparanase, e, célula
EP1060252A2 (en) 1998-02-24 2000-12-20 PHARMACIA & UPJOHN COMPANY Human platelet heparanase polypeptides, polynucleotide molecules that encode them, and methods for the identification of compounds that alter heparanase activity
AU2878600A (en) * 1999-03-01 2000-09-21 Hadasit Medical Research Services & Development Company Ltd Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells
AU2001294563A1 (en) 2000-09-15 2002-03-26 Reddy Us Therapeutics, Inc Methods and compositions for glycosidase assays
US7407773B2 (en) * 2000-11-03 2008-08-05 Procognia, Ltd. Method for characterizing a carbohydrate polymer
WO2002090574A1 (en) * 2001-05-09 2002-11-14 Insight Biopharmaceuticals Ltd. Methods and kits utilizing heparanase as a diagnostic marker for haemostatic disorders
CH696701A5 (de) * 2001-12-18 2007-10-15 Hoffmann La Roche Verfahren zum Testen eines Mittels auf dessen Fähigkeit, die Heparanaseaktivität zu hemmen.
US20050164983A1 (en) * 2003-12-19 2005-07-28 Aventis Pharma S.A. Carboxyl-reduced derivatives of dermatan sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them
WO2005095967A1 (en) * 2004-03-23 2005-10-13 Quidel Corporation Hybrid phase lateral flow assay
US7871568B2 (en) * 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
US7794656B2 (en) * 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
WO2008055575A1 (en) * 2006-11-07 2008-05-15 Hans-Dieter Haubeck Method for determining endoglycosidase (heparanase) enzyme activity
WO2009078015A2 (en) * 2007-12-18 2009-06-25 Procognia (Israel) Ltd Method and assay for glycosylation pattern detection related to cell state of stem cells
CN102965362B (zh) * 2012-11-28 2014-09-03 深圳市海普瑞药业股份有限公司 一种肝素黄杆菌肝素酶ⅱ的制备方法
CN103149198B (zh) * 2013-02-08 2015-04-22 浙江工业大学 一种酶法快速定量检测heparosan的方法
CN104593347B (zh) 2015-03-05 2018-08-28 深圳市海普瑞药业集团股份有限公司 来自Sphingobacterium daejeonense的肝素酶及其制备和应用
WO2021127096A1 (en) * 2019-12-17 2021-06-24 National Jewish Health Methods of detecting lipoarabinomannan and diagnosing nontuberculosis mycobacterial infection

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262403A (en) * 1986-03-10 1993-11-16 Board Of Regents, The University Of Texas System Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II
US4859581A (en) * 1986-03-10 1989-08-22 Board Of Regents, The University Of Texas System Endoglycosidase assay
US5206223A (en) * 1986-06-26 1993-04-27 Yeda Research And Development Co. Ltd. Method for inhibiting heparanase activity
DE69032406T2 (de) * 1989-08-23 1998-10-29 Zvi Fuks Wundheilmittel enthaltend heparanase
EP0532695A1 (en) * 1990-05-31 1993-03-24 Board Of Regents, The University Of Texas System Immunochemical localization of heparanase in mouse and human melanomas
WO1995004158A1 (en) * 1993-07-29 1995-02-09 The Upjohn Company Use of heparanase to identify and isolate anti-heparanase compound
US5739115A (en) * 1993-10-07 1998-04-14 Glycomed Incorporated Sulfated maltooligosaccharides with heparin-like properties

Also Published As

Publication number Publication date
US6352852B1 (en) 2002-03-05
IL128101A (en) 2003-11-23
TW565614B (en) 2003-12-11
NZ333736A (en) 2000-06-23
CN1230219A (zh) 1999-09-29
US6207402B1 (en) 2001-03-27
WO1998003638A1 (en) 1998-01-29
EP0935650A4 (en) 2003-08-20
JP2000515014A (ja) 2000-11-14
EP0935650A1 (en) 1999-08-18
IL128101A0 (en) 1999-11-30
EA003901B1 (ru) 2003-10-30
EA199900138A1 (ru) 1999-06-24
CN1146659C (zh) 2004-04-21
CA2261290A1 (en) 1998-01-29

Similar Documents

Publication Publication Date Title
BR9710735A (pt) Processos para detec-Æo de atividade de heparanase de mamiferos em uma amostra e para purifa-Æo de heparanase de maniferos a partir de um material contendo heparanase kit para uso na detec-Æo da atividade da heparanase de mamiferos em uma amostra e heparanase de mamiferos substancialmente purificada e de plaquetas humanas
BR9301588A (pt) Metodo e aparelho para detectar atividade biologica dentro de uma amostra contida em um recipiente
GB2321967B (en) Opaque reaction matrix for the analysis of whole blood
FI952131A7 (fi) Analyysijärjestelmä potilaan verestä analysoitavan aineen tarkkailemiseksi
HU9501875D0 (en) Dna-rapidtest for detection of chinilonresistent staphylococcus aureus in clinical samples
BR9508586A (pt) Compostos processo de preparação dos mesmos uso dos mesmos processo de tratamento de uma condição clínica em um mamífero e composição farmacêutica
DE69326623D1 (de) Apparat zur detektion und therapie von tachykardie und herzflimmern
DE69324265D1 (de) Apparat zur detektion und therapie von tachykardie und herzflimmern
GB8600582D0 (en) Purifying biological materials
BR8906988A (pt) Tetrapiptidio,peptidio,composicao farmaceutica,processo para uso de peptidio e reagente para diagnostico
IT1254323B (it) Perfezionata composizione biologica in particelle e procedimento per la sua produzione
BR9611519A (pt) Método para quantificação de material biológico em uma amostra
BR9505075A (pt) Meio e método a detecção da presença ou ausência de enetrococci em uma amostra liquefeita e método para quantificar a proporção ou o número de entrocci presentes em uma amostra liquefeita
BR9704483A (pt) Guanididas de ácido alquenilcarboxílico fenil-substituídas processo para sua preparação sua utilização como medicamento ou meio de diagnóstico e medicamento que as contêm
BR9301589A (pt) Metodo e aparelho para identificar a presenca de atividade biologica dentro de uma amostra contida em um frasco;e aparelho para identificar a presenca de atividade biologica dentro de uma amostra contida em um frasco de uma pluralidade de frascos
AU104976S (en) Swab for collection of biological samples
ATE200731T1 (de) Befestigungsstreifen für absorbierende wegwerfartikel
DE69738170D1 (de) Konditioniertes Medium und diffusionsfähiges biologisches Material gewonnen durch Inkubierung von eingeschlossenen Zellen
DE69809554D1 (de) Kunstoffzusammensetzung für klinische behälter und zur lagerung von roten blutkörperchen
FI895215A7 (fi) Menetelmä antitrombiini III:n biologisen aktiivisuuden määrittämiseksi ja reagenssi sitä varten
AU7212198A (en) Preparation of blood samples for detecting homocysteine and/or folate
IL93592A0 (en) Mammalian cell line and its use for detecting certain molecules
IL115057A0 (en) Pharmaceutical which is suitable for employment as an antidote to blood anticoagulants and its use
GB8814933D0 (en) Detecting biological contamination
GB9420641D0 (en) Blood sample analysis

Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements