[go: up one dir, main page]

BR9710355A - Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal. - Google Patents

Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal.

Info

Publication number
BR9710355A
BR9710355A BR9710355-1A BR9710355A BR9710355A BR 9710355 A BR9710355 A BR 9710355A BR 9710355 A BR9710355 A BR 9710355A BR 9710355 A BR9710355 A BR 9710355A
Authority
BR
Brazil
Prior art keywords
virus
mammal
compositions
hepatitis
hiv
Prior art date
Application number
BR9710355-1A
Other languages
English (en)
Inventor
Hsiu-Hsien Tsai
Shie Ming Hwang
Original Assignee
Hsiu Hsien Tsai E Shi Ming Hwa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hsiu Hsien Tsai E Shi Ming Hwa filed Critical Hsiu Hsien Tsai E Shi Ming Hwa
Priority claimed from PCT/US1997/012293 external-priority patent/WO1998001144A2/en
Publication of BR9710355A publication Critical patent/BR9710355A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPOSIçãO úTIL PARA O TRATAMENTO DE INFECçõES VIRAIS EM UM MAMìFERO, PROCESSO PARA TRATAR UMA INFECçãO VIRAL EM UM MAMìFERO, E, PRODUTO MEDICINAL". Esta invenção refere-se às composições derivadas de medicamentos herbáceos chineses, às plantas medicinais e ao seu uso para o tratamento de animais infectados com vírus da hepatite B (HBV), vírus da hepatite C (HCV) e vírus da imunodeficiência humana (HIV). Mais especificamente, as composições da presente invenção são derivadas de vários medicamentos herbáceos chineses que apresentam uma longa história de consumo humano. As composições da invenção são obtidas através de técnicas específicas e têm demonstrado eficácia notável no tratamento de portadores de HBV humano e pacientes com hepatite C. Composições de acordo com a invenção também têm exibido atividades antivirais in vitro contra vírus da leucemia de murídeos (MuLV) e HIV. HIV é o vírus conhecido por causar a síndrome da imunodeficiência adquirida (AIDS) em humanos e AIDS apresenta problemas especiais à comunidade médica que são solucionados pela presente invenção.
BR9710355-1A 1996-07-09 1997-07-09 Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal. BR9710355A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1610096P 1996-07-09 1996-07-09
US2146796P 1996-07-10 1996-07-10
PCT/US1997/012293 WO1998001144A2 (en) 1996-07-09 1997-07-09 Antiviral agents from plant extracts and use for treatment of viral infections

Publications (1)

Publication Number Publication Date
BR9710355A true BR9710355A (pt) 2000-01-11

Family

ID=26688168

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9710355-1A BR9710355A (pt) 1996-07-09 1997-07-09 Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal.

Country Status (11)

Country Link
US (3) US5837257A (pt)
EP (1) EP0914139B1 (pt)
JP (1) JP2001516337A (pt)
KR (1) KR100511514B1 (pt)
AT (1) ATE387208T1 (pt)
AU (1) AU742854B2 (pt)
BR (1) BR9710355A (pt)
CA (1) CA2271622C (pt)
DE (1) DE69738535T2 (pt)
ES (1) ES2303342T3 (pt)
NZ (1) NZ333707A (pt)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100346609B1 (ko) * 1994-12-28 2002-11-18 주식회사 엘지씨아이 금은화로부터세코노가노사이드를추출하는방법
US5837257A (en) * 1996-07-09 1998-11-17 Sage R&D Use of plant extracts for treatment of HIV, HCV and HBV infections
KR100239879B1 (ko) * 1997-11-05 2000-02-01 김상조 간암 예방 및 치료용 생약제
US6524625B2 (en) * 1998-06-30 2003-02-25 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyuto Physiologically active extract obtained from indigo plant polygonum tinctorium
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
EP1171141B1 (de) * 1999-04-14 2004-10-20 Max Zeller Söhne AG ARZNEIMITTEL ZUR HEMMUNG DES NF-kB TRANSKRIPTIONSFAKTORS
WO2001003748A1 (en) * 1999-07-13 2001-01-18 Deuk Hun Ahn Herb medicine composition to be spread on sanitary napkin for female
AU765724B2 (en) 1999-08-13 2003-09-25 University Of Maryland Biotechnology Institute Compositions for treating viral infections, and methods therefor
US6103242A (en) * 1999-10-21 2000-08-15 Buckley; William Method of controlling blood sugar levels using Coccoloba uvifera
CN1173965C (zh) * 2000-03-30 2004-11-03 科学与工业研究会 从植物黄花蒿中分离化合物东莨菪亭的方法
WO2001089476A1 (en) * 2000-05-19 2001-11-29 Npd Llc Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
US7045159B1 (en) * 2000-09-19 2006-05-16 Rutgers, The State University Of New Jersey Antiviral substances from plant cuticular and epiciticular material
US6455078B1 (en) 2000-10-18 2002-09-24 Tzu-Sheng Wu Medicinal herbal composition for treating liver diseases and HIV
US6696094B2 (en) * 2000-10-18 2004-02-24 Tzu-Sheng Wu Herbal pharmaceutical composition for treatment of HIV/AIDS patients
CN1309399C (zh) * 2000-10-25 2007-04-11 国家中药制药工程技术研究中心 复方双黄连制剂及制备方法
AU2002227252A1 (en) * 2000-12-01 2002-06-11 Cornell Research Foundation Animal model for flaviviridae infection
JP4880816B2 (ja) * 2000-12-15 2012-02-22 株式会社ヤクルト本社 皮膚老化防止剤
US6455070B1 (en) 2001-02-15 2002-09-24 East Park Research, Inc. Composition for treating symptoms of influenza
ATE326980T1 (de) * 2001-04-02 2006-06-15 Hongfen Li Pharmazeutisches asthmapräparat
US20030054047A1 (en) * 2001-06-15 2003-03-20 Sanjiu Medical & Pharmaceutical Co., Ltd. Pharmaceutical composition for the treatment of viral infection
US20030054978A1 (en) * 2001-08-31 2003-03-20 Babish John G. Arginine compositions for coordinate modification of multiple cardiovascular risk factors
US7138376B2 (en) * 2001-09-28 2006-11-21 Idenix Pharmaceuticals, Inc. Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides
WO2003030635A1 (en) * 2001-10-11 2003-04-17 Natural Remedies Private Limited A herbal hepatoprotective and weight gain promoter and a process thereof
US6541045B1 (en) * 2002-01-04 2003-04-01 Nutraceutical Corporation Herbal composition and method for combating inflammation
MY140819A (en) 2002-06-28 2010-01-29 Idenix Caymans Ltd Modified 2' and 3'-nucleoside prodrugs for treating flaviviridae
AU2003244587B2 (en) * 2002-07-12 2009-06-25 Academia Sinica Use of Anoectochilus Formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies
US7033617B2 (en) * 2002-07-12 2006-04-25 Academia Sinica Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies
JP2006507235A (ja) * 2002-08-01 2006-03-02 フアーマセツト・インコーポレイテツド フラビウイルス科ウイルス感染治療のためのビシクロ[4.2.1]ノナン系を有する化合物
US20040151787A1 (en) * 2002-11-21 2004-08-05 Pero Ronald W. Water soluble compositions derived from plant material and preparation thereof
US20040126351A1 (en) * 2002-12-26 2004-07-01 Avon Products, Inc. Topical composition having natural skin anti-irritant ingredient and method of use
CA2513655C (en) * 2003-01-21 2011-11-22 Chiron Corporation Use of tryptanthrin compounds for immune potentiation
TWI269656B (en) * 2003-03-05 2007-01-01 Original Image Co Ltd Therapeutical composition for hepatitis C
KR101000953B1 (ko) * 2003-05-16 2010-12-13 안경민 비수리 추출물 및 그 용도
US20040234546A1 (en) * 2003-05-19 2004-11-25 Amazon Biotech Inc. Treatments using an herbal composition
US7160561B2 (en) 2003-05-19 2007-01-09 Amazon Biotech Inc. Herbal composition and method of treating HIV infection
CA2734052A1 (en) 2003-05-30 2005-01-13 Pharmasset, Inc. Modified fluorinated nucleoside analogues
US7648717B2 (en) * 2003-06-13 2010-01-19 Industrial Technology Research Institute Herbal extract having anti-virus activity and preparation of same
TWI315200B (en) * 2003-06-13 2009-10-01 Ind Tech Res Inst An herbal extract having anti-enterovirus activity and preparation of same
CN1852915A (zh) 2003-07-25 2006-10-25 艾登尼科斯(开曼)有限公司 治疗包括丙型肝炎的黄病毒科病毒所致疾病的嘌呤核苷类似物
FR2859107B1 (fr) * 2003-08-26 2008-04-18 Oyoubi Pierre Pyebi Utilisation des extraits d'une graminee, d'une rutacee et d'une pieridophyte dans une composition pharmaceutique a activite antivirale, antibacterienne, antifongique et aussi destinee a stimuler les defenses immunitaires
GB0500020D0 (en) 2005-01-04 2005-02-09 Novartis Ag Organic compounds
CN1330359C (zh) * 2004-04-09 2007-08-08 北京琦杰源医药科技发展有限公司 一种治疗艾滋病的中药制剂及其加工方法
SE0400996D0 (sv) * 2004-04-16 2004-04-16 Alltech Ireland Inc Use of plants, plant extracts and nature-identical components from plants to affect the rumen fermentation and to improve the energy and protein retention of ruminants
CN101023094B (zh) 2004-07-21 2011-05-18 法莫赛特股份有限公司 烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
US8008280B2 (en) * 2004-09-10 2011-08-30 Biorings Llc Betulinol derivatives as anti-HIV agents
BRPI0515279A (pt) 2004-09-14 2008-07-15 Pharmasset Inc preparação de ribofuranosil pirimidinas e purinas 2'fluoro-2'-alquil- substituìdas ou outras opcionalmente substituìdas e seus derivados
US20060110479A1 (en) * 2004-11-24 2006-05-25 Mitra Shankar K Natural composition for curing hepatitis-B, methods for making the same and pharmaceutical formulations thereof
US7615240B2 (en) * 2005-01-07 2009-11-10 Auburn University Method and composition for the control of gastrointestinal parasites in animals
KR100661032B1 (ko) * 2005-04-19 2006-12-22 주식회사한국야쿠르트 간 기능 개선, 혈중 알코올 감소 및 항산화에 유효한조성물
US7556830B2 (en) * 2005-08-22 2009-07-07 International Patents Holdings, Ltd. Medicinal herbal composition for treating infection
DE202005015707U1 (de) * 2005-10-06 2006-04-20 Sheng Foong Pharmaceutical Co. Ltd., Su-Ao Chen Kräuterzusammensetzung zur Behandlung von Krebs
US8980336B2 (en) * 2005-12-30 2015-03-17 Industrial Technology Research Institute Method for inhibiting free radicals
TWI370739B (en) * 2005-12-30 2012-08-21 Ind Tech Res Inst Herbal compositions of inhibiting free radicals
WO2007133865A2 (en) 2006-04-11 2007-11-22 Novartis Ag Hcv/hiv inhibitors an their uses
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
US20080057111A1 (en) * 2006-08-29 2008-03-06 Lixian Jiang Herbal composition for flu prevention and treatment
WO2008088806A1 (en) * 2007-01-16 2008-07-24 Johns Hopkins University Combinational paradigm combating hiv, hiv/hsv, or hiv/hpv infections in humans using small molecular weight compounds from plants
EP2144604B1 (en) 2007-02-28 2011-09-21 Conatus Pharmaceuticals, Inc. Methods for the treatment of chronic viral hepatitis C using RO 113-0830
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
US20080254148A1 (en) * 2007-04-13 2008-10-16 Gerent Biotech Co. Herbal compositions for the inhibition of human immunodeficiency virus
US20090053335A1 (en) * 2007-04-13 2009-02-26 Chih-Hui Lin Herbal compositions for the inhibition of human immunodeficiency virus (hiv)
US8067401B2 (en) * 2007-09-06 2011-11-29 International Patent Holdings Llc Compounds and compositions for treating infection
EP2190292A4 (en) * 2007-09-07 2012-12-26 Bionovo Inc ESTROGENWIRKSAME EXTRACTS OF SCUTTELARIA BARBATA D. DON OF THE FAMILY LABIATAE AND ITS USES
TW200946541A (en) * 2008-03-27 2009-11-16 Idenix Pharmaceuticals Inc Solid forms of an anti-HIV phosphoindole compound
TWI366466B (en) * 2008-05-08 2012-06-21 Ind Tech Res Inst Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
ES2458358T3 (es) 2008-07-02 2014-05-05 Idenix Pharmaceuticals, Inc. Compuestos y composiciones farmacéuticas para el tratamiento de infecciones víricas
US8716262B2 (en) 2008-12-23 2014-05-06 Gilead Pharmasset Llc Nucleoside phosphoramidates
EP2376514A2 (en) 2008-12-23 2011-10-19 Pharmasset, Inc. Nucleoside analogs
WO2010075554A1 (en) 2008-12-23 2010-07-01 Pharmasset, Inc. Synthesis of purine nucleosides
EP2403860B1 (en) 2009-03-04 2015-11-04 IDENIX Pharmaceuticals, Inc. Phosphothiophene and phosphothiazole as hcv polymerase inhibitors
US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
US8512690B2 (en) 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors
TWI583692B (zh) * 2009-05-20 2017-05-21 基利法瑪席特有限責任公司 核苷磷醯胺
US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
CA2769652A1 (en) 2009-08-05 2011-02-10 Idenix Pharmaceuticals, Inc. Macrocyclic serine protease inhibitors useful against viral infections, particularly hcv
US20110117055A1 (en) 2009-11-19 2011-05-19 Macdonald James E Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
JP5651834B2 (ja) * 2009-12-14 2015-01-14 豊勝 堀川 赤血球凝集阻害剤、および赤血球の凝集阻害方法
US8362068B2 (en) 2009-12-18 2013-01-29 Idenix Pharmaceuticals, Inc. 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors
ES2660229T3 (es) * 2009-12-30 2018-03-21 Bagi Research Limited Materiales y métodos para la prevención y el tratamiento de infecciones virales
RS54368B1 (sr) 2010-03-31 2016-04-28 Gilead Pharmasset Llc Kristalni (s)-izopropil 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-diokso-3,4-dihidropirimidin-1-(2h)-il)-4-fluoro-3-hidroksi-4-metiltetrahidrofuran-2-il)metoksi)(fenoksi)fosforil)amino)propanoat
PL3290428T3 (pl) 2010-03-31 2022-02-07 Gilead Pharmasset Llc Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
MX2012011222A (es) 2010-04-01 2013-01-18 Centre Nat Rech Scient Compuestos y composiciones farmaceuticas para el tratamiento de infecciones virales.
JP5909495B2 (ja) 2010-10-08 2016-04-26 ノバルティス アーゲー スルファミドns3阻害剤のビタミンe製剤
CA2818853A1 (en) 2010-11-30 2012-06-07 Gilead Pharmasset Llc 2'-spirocyclo-nucleosides for use in therapy of hcv or dengue virus
WO2012080050A1 (en) 2010-12-14 2012-06-21 F. Hoffmann-La Roche Ag Solid forms of a phenoxybenzenesulfonyl compound
KR20120080674A (ko) * 2011-01-08 2012-07-18 주식회사한국전통의학연구소 대계근 추출물을 포함하는 백혈병 치료용 조성물 및 건강 기능성 식품
US8618125B2 (en) 2011-01-14 2013-12-31 Heptiva LLC Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance
TW201309690A (zh) 2011-02-10 2013-03-01 Idenix Pharmaceuticals Inc 巨環絲胺酸蛋白酶抑制劑,其醫藥組合物及其於治療hcv感染之用途
EP2691409B1 (en) 2011-03-31 2018-02-21 Idenix Pharmaceuticals LLC. Compounds and pharmaceutical compositions for the treatment of viral infections
US20120252721A1 (en) 2011-03-31 2012-10-04 Idenix Pharmaceuticals, Inc. Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
WO2012143017A1 (en) * 2011-04-17 2012-10-26 El-Sawy Mohamed Fakhr El-Din The use of orobancheace extract for the treatment of hepatitis c virus and nonalcoholic fatty liver disease
AR088441A1 (es) 2011-09-12 2014-06-11 Idenix Pharmaceuticals Inc Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
CA2847892A1 (en) 2011-09-12 2013-03-21 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of viral infections
AR089650A1 (es) 2011-10-14 2014-09-10 Idenix Pharmaceuticals Inc Fosfatos 3,5-ciclicos sustituidos de compuestos de nucleotido de purina y composiciones farmaceuticas para el tratamiento de infecciones virales
US8889159B2 (en) 2011-11-29 2014-11-18 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus
ES3018133T3 (en) 2011-11-30 2025-05-14 Univ Emory Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae
US8809354B2 (en) 2011-12-31 2014-08-19 Sheikh Riazuddin 3-amino-2-(4-nitrophenyl)-4-(3H)-quinazolinone or derivatives thereof for treating or preventing antiviral infections
WO2013133927A1 (en) 2012-02-13 2013-09-12 Idenix Pharmaceuticals, Inc. Pharmaceutical compositions of 2'-c-methyl-guanosine, 5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl n-(phenylmethyl)phosphoramidate]
TWI498118B (zh) * 2012-04-27 2015-09-01 財團法人工業技術研究院 促進傷口癒合及血管新生的醫藥組合物與接骨木屬(蒴藋屬)(Sambucus)植物及菘藍屬(Isatis)植物之萃取物用於製備促進傷口癒合及血管新生之藥物的用途
US9296778B2 (en) 2012-05-22 2016-03-29 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphate prodrugs for HCV infection
CA2873315A1 (en) 2012-05-22 2013-11-28 Idenix Pharamaceuticals, Inc. D-amino acid compounds for liver disease
US9109001B2 (en) 2012-05-22 2015-08-18 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphoramidate prodrugs for HCV infection
MX353422B (es) 2012-10-08 2018-01-12 Idenix Pharmaceuticals Llc Análogos de 2'-cloronucleósido para infección por vhc.
WO2014063019A1 (en) 2012-10-19 2014-04-24 Idenix Pharmaceuticals, Inc. Dinucleotide compounds for hcv infection
WO2014066239A1 (en) 2012-10-22 2014-05-01 Idenix Pharmaceuticals, Inc. 2',4'-bridged nucleosides for hcv infection
EP2920195A1 (en) 2012-11-14 2015-09-23 IDENIX Pharmaceuticals, Inc. D-alanine ester of rp-nucleoside analog
EP2938624A1 (en) 2012-11-14 2015-11-04 IDENIX Pharmaceuticals, Inc. D-alanine ester of sp-nucleoside analog
WO2014099941A1 (en) 2012-12-19 2014-06-26 Idenix Pharmaceuticals, Inc. 4'-fluoro nucleosides for the treatment of hcv
US9339541B2 (en) 2013-03-04 2016-05-17 Merck Sharp & Dohme Corp. Thiophosphate nucleosides for the treatment of HCV
WO2014137926A1 (en) 2013-03-04 2014-09-12 Idenix Pharmaceuticals, Inc. 3'-deoxy nucleosides for the treatment of hcv
EP2981542B1 (en) 2013-04-01 2021-09-15 Idenix Pharmaceuticals LLC 2',4'-fluoro nucleosides for the treatment of hcv
EP3004130B1 (en) 2013-06-05 2019-08-07 Idenix Pharmaceuticals LLC. 1',4'-thio nucleosides for the treatment of hcv
EP3027636B1 (en) 2013-08-01 2022-01-05 Idenix Pharmaceuticals LLC D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
SG11201600919UA (en) 2013-08-27 2016-03-30 Gilead Pharmasset Llc Combination formulation of two antiviral compounds
WO2015042375A1 (en) 2013-09-20 2015-03-26 Idenix Pharmaceuticals, Inc. Hepatitis c virus inhibitors
WO2015061683A1 (en) 2013-10-25 2015-04-30 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
US20160271162A1 (en) 2013-11-01 2016-09-22 Idenix Pharmacueticals, Llc D-alanine phosphoramide pronucleotides of 2'-methyl 2'-fluro guanosine nucleoside compounds for the treatment of hcv
WO2015081297A1 (en) 2013-11-27 2015-06-04 Idenix Pharmaceuticals, Inc. 2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
EP3084660B1 (en) 2013-12-16 2021-12-01 3M Innovative Properties Company Systems and methods for controlling humidity
WO2015095419A1 (en) 2013-12-18 2015-06-25 Idenix Pharmaceuticals, Inc. 4'-or nucleosides for the treatment of hcv
EP3114122A1 (en) 2014-03-05 2017-01-11 Idenix Pharmaceuticals LLC Solid forms of a flaviviridae virus inhibitor compound and salts thereof
US20170135990A1 (en) 2014-03-05 2017-05-18 Idenix Pharmaceuticals Llc Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
WO2015161137A1 (en) 2014-04-16 2015-10-22 Idenix Pharmaceuticals, Inc. 3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
US9789153B2 (en) 2014-07-02 2017-10-17 Hsiu-Hsien Tsai Composition for preventing cancer and treating cancer and intensifying the effects of other anticancer drugs
CN109917034A (zh) * 2019-03-19 2019-06-21 遵义医科大学 一种白及悬浮培养细胞中2,7-二羟基-4-甲氧基-9,10-二氢菲的定量检测方法
CN110179951A (zh) * 2019-06-28 2019-08-30 宗吉红 一种调治病毒性肝炎的中药组合物及其制备方法
KR102321162B1 (ko) * 2019-11-25 2021-11-02 강원대학교 산학협력단 황백 추출물을 유효성분으로 포함하는 산화아연 저감 사료용 보조제 조성물
WO2022131903A1 (en) * 2020-12-14 2022-06-23 Xie Li Products Co., Ltd. Herbal composition, method for preparing same and method for preventing or treating viral infections by administering the same
WO2022174068A1 (en) * 2021-02-12 2022-08-18 Arizona Board Of Regents On Behalf Of Arizona State University Oral botanical composition
KR102607247B1 (ko) * 2021-03-25 2023-11-29 한국식품연구원 도깨비고비 추출물을 유효성분으로 포함하는 항암 조성물
US20210361733A1 (en) * 2021-08-06 2021-11-25 Atta-ur- Rahman Prevention and Treatment of SARS-CoV-2 Infection by Mentha piperita and Flos chrysanthemi Extracts alone, and their Combination
KR102389589B1 (ko) * 2021-09-29 2022-04-22 진지영 야관문 추출물을 포함하는 사료용 항진균성 조성물 및 그의 제조 방법
PL245314B1 (pl) * 2022-07-15 2024-06-24 Inst Chemii Fizycznej Polskiej Akademii Nauk Zastosowanie soli sodowej kwasu 5,5’-indygodisulfonowego do hamowania infekcji bakteriofagowych w procesach biotechnologicznych
CN117562962B (zh) * 2024-01-15 2024-03-12 四川育强本草生物技术有限公司 美洲大蠊或其提取物的用途及一种治疗猫口炎的中兽药组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808629A (en) * 1985-05-28 1989-02-28 Yaguang Liu Safe antileukemia drug, SAL
JPS6299318A (ja) * 1985-10-25 1987-05-08 Nonogawa Shoji:Kk 養毛剤
US4886666A (en) * 1987-01-27 1989-12-12 Yaguang Liu Pharmaceutical composition for inhibiting viruses and increasing immune function (PII)
US4985248A (en) * 1987-06-18 1991-01-15 Yaguang Liu Pharmaceutical composition containing a safe extracts of fruits and vegetables for the treating and preventing of diabetes
JP2974370B2 (ja) * 1990-05-11 1999-11-10 社団法人北里研究所 シアリダーゼ阻害剤
JPH0426650A (ja) * 1990-05-17 1992-01-29 Kuraray Co Ltd オレアノール酸の製造法
US5178865A (en) * 1990-06-19 1993-01-12 Cedars-Sinai Medical Center Chinese herbal extracts in the treatment of hiv related disease in vitro
US5366725A (en) * 1990-06-27 1994-11-22 Shinya Okubo Method for the treatment of cancer
CN1077379A (zh) * 1992-04-16 1993-10-20 张笑平 乙肝表面抗原转阴冲剂及其制备方法
US5411733A (en) * 1992-04-27 1995-05-02 Hozumi; Toyoharu Antiviral agent containing crude drug
CN1049338C (zh) * 1993-03-20 2000-02-16 赵三立 治疗乙型肝炎的药液
JP3183754B2 (ja) * 1993-07-20 2001-07-09 ポーラ化成工業株式会社 動脈硬化抑制剤及びこれを含有する組成物
US5837257A (en) * 1996-07-09 1998-11-17 Sage R&D Use of plant extracts for treatment of HIV, HCV and HBV infections

Also Published As

Publication number Publication date
US5989556A (en) 1999-11-23
AU3664297A (en) 1998-02-02
JP2001516337A (ja) 2001-09-25
US5837257A (en) 1998-11-17
ATE387208T1 (de) 2008-03-15
NZ333707A (en) 2000-09-29
EP0914139A2 (en) 1999-05-12
KR100511514B1 (ko) 2005-08-31
CA2271622C (en) 2002-12-17
WO1998001144A1 (en) 1998-01-15
US6214350B1 (en) 2001-04-10
CA2271622A1 (en) 1998-01-15
KR20000023648A (ko) 2000-04-25
DE69738535T2 (de) 2009-02-19
AU742854B2 (en) 2002-01-17
ES2303342T3 (es) 2008-08-01
EP0914139B1 (en) 2008-02-27
DE69738535D1 (de) 2008-04-10

Similar Documents

Publication Publication Date Title
BR9710355A (pt) Composição útil para o tratamento de infecções virais em um mamìfero, processo para tratar uma infecção viral em um mamìfero, e, produto medicinal.
WO2003051306A3 (en) N4-acylcytosine-1,3-dioxolane nucleosides for treatment of viral infections
ATE264914T1 (de) Antivirale proteine, dafür kodierende dna, und deren verwendung
RU94002475A (ru) Фармацевтическая композиция и ее применение для лечения вирусных инфекций
ATE345353T1 (de) Langwirkende fusionspeptidinhibitoren gegen hiv- infektion
WO2001010456A3 (en) Peptides that block viral infectivity and methods of use thereof
ES2187530T3 (es) Peptidos para reducir respuestas de linfocito t ctitotoxicos al virus de la hepatitis b.
PT92949A (pt) Processo para a preparacao de composicoes farmaceuticas contendo derivados da cisteina para o tratamento de doencas associadas com infeccoes provocadas por virus da imunodeficiencia humano
BR9913333A (pt) Inibição e tratamento do vìrus da hepatite b e flavivìrus com helioxatina e seus análogos
GEP20084377B (en) Agent for inhibiting membrane virus reproduction, method for the production thereof, pharmaceutical composition and method for inhibiting viral infections
PT777669E (pt) Utilizacao de succinato de 4-(2-amino-6-(ciclopropilamino)-9h-purin-9-il)-2-ciclopenteno-1-metanol como agente antiviral
WO2007033444A3 (en) Antiviral therapy with carbohydrate binding agents
SG170825A1 (en) Phosponate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production
EP0681578A1 (en) ANTIVIRAL NAPHTOQUINONE COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND USES THEREOF.
MX9301922A (es) Composiciones para el tratamiento de infeccion y enfermedad ocasionadas por el virus de hepatitis b (hbv).
MX9700414A (es) Agentes antivirales de difluoroestatona.
RU93058325A (ru) Применение производных 1,3-оксатиолана для получения лекарственных препаратов для лечения или профилактики вирусной инфекции гепатита в, применение производных 1,3 - оксатиолана для лечения инфекций гепатита в, способ лечения гепатита в
MY157594A (en) Compositions of matter useful in the treatment of viral infections derived from plant extracts
BG101175A (bg) Тройна анти-нiv комбинация
AU2880595A (en) Use of pharmaceutical agents for restoring, alleviation, or treatment of immunodeficiency, including the alleviation or treatment of the immune dysfunction related to infection with human immunodeficiency viruses (hiv) or related viruses
WO1998001144A2 (en) Antiviral agents from plant extracts and use for treatment of viral infections
CA2401295A1 (en) Process for preparing an anti viral medicinal product from plant extracts
KR950702838A (ko) 인터루킨-4(IL-4)를 사용한 사람 면역결핍 바이러스(HIV) 복제의 억제방법(Method for inhibiting HIV replication using IL-4)
UA41338C2 (uk) Спосіб інгібування ретровірусної інфекції, яка викликана вірусом імунодефіциту людини (віл), спосіб інгібування вірусу імунодефіциту людини (віл)
UA42693C2 (uk) Лікарський засіб для лікування інфекції лентивірусом, препарат для лікування людини, яка інфікована лентивірусом

Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 25 E 32 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.

B15K Others concerning applications: alteration of classification

Ipc: A61K 36/00 (2006.01), A61K 36/28 (2006.0