BR9709529A - Leptin fragments (ob protein) - Google Patents

Leptin fragments (ob protein)

Info

Publication number: BR9709529A
Authority: BR; Brazil
Prior art keywords: protein; leptin fragments; leptin; fragments
Prior art date: 1996-06-06

Application number

BR9709529A

Other languages

Portuguese (pt)

Inventor

Kamal A Al-Barazanji

Jonathan Robert Sanders Arch

Patrick Camilleri

William Arthur Neville

Original Assignee

Smithkline Beecham P L C Socie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-06

Filing date

1997-06-04

Publication date

1999-08-10

1996-06-06 Priority claimed from GBGB9611775.9A external-priority patent/GB9611775D0/en

1996-09-05 Priority claimed from GBGB9618540.0A external-priority patent/GB9618540D0/en

1997-02-20 Priority claimed from GBGB9703493.8A external-priority patent/GB9703493D0/en

1997-06-04 Application filed by Smithkline Beecham P L C Socie filed Critical Smithkline Beecham P L C Socie

1999-08-10 Publication of BR9709529A publication Critical patent/BR9709529A/en

Links

102000016267 Leptin Human genes 0.000 title 1
108010092277 Leptin Proteins 0.000 title 1
NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical group O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
Toxicology (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Child & Adolescent Psychology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

BR9709529A 1996-06-06 1997-06-04 Leptin fragments (ob protein) BR9709529A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB9611775.9A GB9611775D0 (en)	1996-06-06	1996-06-06	Novel compounds
GBGB9618540.0A GB9618540D0 (en)	1996-09-05	1996-09-05	Novel compounds
GBGB9703493.8A GB9703493D0 (en)	1997-02-20	1997-02-20	Novel compounds
PCT/EP1997/002968 WO1997046585A2 (en)	1996-06-06	1997-06-04	Fragments of leptin (ob protein)

Publications (1)

Publication Number	Publication Date
BR9709529A true BR9709529A (en)	1999-08-10

Family

ID=27268305

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9709529A BR9709529A (en)	1996-06-06	1997-06-04	Leptin fragments (ob protein)

Country Status (15)

Country	Link
EP (1)	EP0912609A2 (en)
JP (1)	JP2000512137A (en)
KR (1)	KR20000016402A (en)
CN (1)	CN1221426A (en)
AR (1)	AR008765A1 (en)
AU (1)	AU3337297A (en)
BR (1)	BR9709529A (en)
CA (1)	CA2257240A1 (en)
CZ (1)	CZ397898A3 (en)
IL (1)	IL127153A0 (en)
NO (1)	NO985683D0 (en)
NZ (1)	NZ332879A (en)
PL (1)	PL330361A1 (en)
TR (1)	TR199802534T2 (en)
WO (1)	WO1997046585A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6001968A (en)	1994-08-17	1999-12-14	The Rockefeller University	OB polypeptides, modified forms and compositions
ATE278952T1 (en)	1998-07-28	2004-10-15	Vlaams Interuniv Inst Biotech	LEPTIN-MEDIATED GENE INDUCTION
US7208572B2 (en) *	1998-08-21	2007-04-24	Albany Medical College	Leptin-related peptides
US6777388B1 (en)	1998-08-21	2004-08-17	Clf Medical Technology Acceleration Program, Inc.	Leptin-related peptides
US6420339B1 (en)	1998-10-14	2002-07-16	Amgen Inc.	Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
WO2001021647A2 (en) *	1999-09-22	2001-03-29	Genset	Methods of screening for compounds that modulate the lsr-leptin interaction and their use in the prevention and treatment of obesity-related diseases
EP1612221A3 (en)	2000-05-22	2008-07-23	Vlaams Interuniversitair Instituut voor Biotechnologie vzw.	Receptor-based interaction trap
JP2005506994A (en)	2001-10-22	2005-03-10	アムジェンインコーポレイテッド	Use of leptin to treat human adipose tissue atrophy and a predisposition method for the treatment
DE602004012759T2 (en)	2003-09-08	2008-07-17	Laboratoires Serono S.A., Coinsins	TREATMENT OF FIBROSES
EP2417980A1 (en)	2004-02-11	2012-02-15	Amylin Pharmaceuticals Inc.	Hybrid polypeptides with selectable properties
WO2006053883A1 (en)	2004-11-18	2006-05-26	Vib Vzw	Fibronectin iii domain as leptin receptor antagonists
BRPI0606992A2 (en)	2005-02-11	2009-07-28	Amylin Pharmaceuticals Inc	gip analog and polypeptides with selectable properties
US7629315B2 (en)	2005-03-09	2009-12-08	University Of Pittsburgh Of The Commonwealth System Of Higher Education	Compositions for blocking the inhibitory effect of human CRP on human leptin
BRPI0614649A2 (en)	2005-08-11	2011-04-12	Amylin Pharmaceuticals Inc	hybrid polypeptides with selectable properties
EP2330124B1 (en)	2005-08-11	2015-02-25	Amylin Pharmaceuticals, LLC	Hybrid polypeptides with selectable properties
ES2319048B1 (en) *	2007-06-20	2010-02-10	Universitat De Les Illes Balears	USE OF LEPTINE IN THE TREATMENT OF ALTERATIONS IN FOOD HABITS.
US8889622B2 (en)	2007-07-25	2014-11-18	Washington University	Methods of inhibiting seizure in a subject
GB2451858A (en) *	2007-08-15	2009-02-18	Sergiy Konovchuk	Methods of reducing body fat and treating obesity
US7851471B2 (en)	2007-12-05	2010-12-14	Astrazeneca Ab (Publ)	Compounds I
BRPI0820950A2 (en)	2007-12-05	2015-07-07	Astrazeneca Ab	Compound, pharmaceutical formulation, use of a compound, methods for treating or preventing conditions or diseases and for inhibiting angiogenesis, and process for preparing a compound.
CN102143747A (en) *	2008-06-04	2011-08-03	阿斯利康(瑞典)有限公司	New pyridine derivatives as leptin receptor modulator mimetics
AU2009254547A1 (en) *	2008-06-04	2009-12-10	Astrazeneca Ab (Publ)	New compounds V
EP2416797A4 (en)	2009-04-10	2013-04-24	Amylin Pharmaceuticals Llc	AMYLINE AGONIST COMPOUNDS FOR MAMMALS WITH STROGEN DEFICIENCY
US9475839B2 (en) *	2010-05-11	2016-10-25	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Peptide-based inhibitor of interleukin-10 or interferon-gamma signaling
ES2630031T3 (en)	2010-09-28	2017-08-17	Aegerion Pharmaceuticals, Inc.	A chimeric pinniped-human leptin polypeptide with increased solubility
CN104829707B (en) *	2015-05-06	2017-12-19	广东省生物资源应用研究所	The leptin activity peptide and its encoding gene and application of one CD ring and E spiral region mutations
CN110183530A (en)	2019-06-21	2019-08-30	深圳市亚辉龙生物科技股份有限公司	Leptin immunogene, hybridoma, monoclonal antibody, polyclonal antibody and application

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6309853B1 (en) *	1994-08-17	2001-10-30	The Rockfeller University	Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
CA2211656A1 (en) *	1995-01-31	1996-08-08	Margret B. Basinski	Anti-obesity proteins
US5552523A (en) *	1995-01-31	1996-09-03	Eli Lilly And Company	Anti-obesity proteins
AU4766596A (en) *	1995-01-31	1996-08-21	Eli Lilly And Company	Ob gene product antibodies
WO1996031526A1 (en) *	1995-04-06	1996-10-10	Amylin Pharmaceuticals, Inc.	Anti-obesity agents
GB9509164D0 (en) *	1995-05-05	1995-06-28	Smithkline Beecham Plc	Novel compounds

1997
- 1997-06-04 CN CN97195311A patent/CN1221426A/en active Pending
- 1997-06-04 WO PCT/EP1997/002968 patent/WO1997046585A2/en not_active Ceased
- 1997-06-04 JP JP10500240A patent/JP2000512137A/en active Pending
- 1997-06-04 NZ NZ332879A patent/NZ332879A/en not_active IP Right Cessation
- 1997-06-04 AR ARP970102432A patent/AR008765A1/en unknown
- 1997-06-04 AU AU33372/97A patent/AU3337297A/en not_active Abandoned
- 1997-06-04 EP EP97929156A patent/EP0912609A2/en not_active Withdrawn
- 1997-06-04 CZ CZ983978A patent/CZ397898A3/en unknown
- 1997-06-04 CA CA002257240A patent/CA2257240A1/en not_active Abandoned
- 1997-06-04 TR TR1998/02534T patent/TR199802534T2/en unknown
- 1997-06-04 PL PL97330361A patent/PL330361A1/en unknown
- 1997-06-04 KR KR1019980709976A patent/KR20000016402A/en not_active Ceased
- 1997-06-04 IL IL12715397A patent/IL127153A0/en unknown
- 1997-06-04 BR BR9709529A patent/BR9709529A/en not_active Application Discontinuation
1998
- 1998-12-04 NO NO985683A patent/NO985683D0/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO985683L (en)	1998-12-04
CA2257240A1 (en)	1997-12-11
WO1997046585A2 (en)	1997-12-11
NZ332879A (en)	2000-09-29
CZ397898A3 (en)	1999-04-14
TR199802534T2 (en)	1999-03-22
EP0912609A2 (en)	1999-05-06
AR008765A1 (en)	2000-02-23
PL330361A1 (en)	1999-05-10
AU3337297A (en)	1998-01-05
IL127153A0 (en)	1999-09-22
JP2000512137A (en)	2000-09-19
NO985683D0 (en)	1998-12-04
KR20000016402A (en)	2000-03-25
WO1997046585A3 (en)	1998-04-23
CN1221426A (en)	1999-06-30

Publication	Publication Date	Title
BR9709529A (en)	1999-08-10	Leptin fragments (ob protein)
DE69724557D1 (en)	2003-10-09	document analysis
DE69722620D1 (en)	2003-07-10	NON-AQUEOUS PROTICAL PEPTIDE PREPARATIONS
NO985680L (en)	1999-02-04	peptide
NO983849D0 (en)	1998-08-21	peptide
BR9610239A (en)	1999-06-15	Xcd32-allergen-fusion proteins
DE59707298D1 (en)	2002-06-20	DESODORING PREPARATIONS
GB9614033D0 (en)	1996-09-04	Modified protein G and fragments thereof
TR199701666A3 (en)	1999-10-21	Proteins
DE69925271D1 (en)	2005-06-16	ANGIOSTATIN-BINDING PROTEIN
FR2865535B1 (en)	2006-06-23	indenter
DE69718328T2 (en)	2004-01-15	magnetron
DE59602924D1 (en)	1999-10-07	Bone rasp
DE59702387D1 (en)	2000-10-26	MEDICAL PLIERS
KR970004260U (en)	1997-02-19	Orthopedic Colset
BR7601137U (en)	1998-07-14	Bone
GB9604865D0 (en)	1996-05-08	Modified proteins
HK1019756A (en)	2000-06-02	Fragments of leptin (ob protein)
AU2003204475A1 (en)	2003-06-26	Fragments of leptin (ob protein)
KR970059003U (en)	1997-11-10	Joint Boot
KR970064121U (en)	1997-12-11	magnetron
SE9602287D0 (en)	1996-06-10	Novel protein and methods for its use
SE9601761D0 (en)	1996-05-08	T-valve procedure
ID16704A (en)	1997-11-06	HEALING METHOD
KR970060687U (en)	1997-12-10	Condom

Legal Events

Date	Code	Title	Description
2006-12-12	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2007-04-27	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR.PORTANTO, INDEFIRO O PRESENTE PEDIDO.