[go: up one dir, main page]

BR9707056A - Processos e composições para determinar a sequência de moléculas de ácido nucleico - Google Patents

Processos e composições para determinar a sequência de moléculas de ácido nucleico

Info

Publication number
BR9707056A
BR9707056A BR9707056-4A BR9707056A BR9707056A BR 9707056 A BR9707056 A BR 9707056A BR 9707056 A BR9707056 A BR 9707056A BR 9707056 A BR9707056 A BR 9707056A
Authority
BR
Brazil
Prior art keywords
nucleic acid
sequence
processes
compositions
acid molecules
Prior art date
Application number
BR9707056-4A
Other languages
English (en)
Other versions
BR9707056B1 (pt
Inventor
Jeffrey Van Ness
John C Tabone
J Jeffry Howbert
John T Mulligan
Original Assignee
Rapigene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26681206&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9707056(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rapigene Inc filed Critical Rapigene Inc
Publication of BR9707056A publication Critical patent/BR9707056A/pt
Publication of BR9707056B1 publication Critical patent/BR9707056B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6872Methods for sequencing involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11Compounds covalently bound to a solid support
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Saccharide Compounds (AREA)

Abstract

''PROCESSOS E COMPOSIçõES PARA DETERMINAR A SEQuêNCIA DE MOLéCULAS DE áCIDO NUCLEICO''. São providos processos e compostos, incluindo composições dos mesmos, para determinar a seq³ência de moléculas de ácido nucleico. Os processos permitem a determinação, simultânea, de seq³ências de ácido nucleico múltiplas. Os compostos são usados como rótulos para gerar fragmentos de ácido nucleico rotulados, que são complementares a uma molécula de ácido nucleico alvo selecionada. Cada rótulo é correlato a um nucleotídeo específico e, em uma concretização preferida, é detectável por espectroscopia de massa. Seguindo-se a separação dos fragmentos rotulados pelo comprimento seq³encial, os rótulos são clivados a partir de fragmentos rotulados. Em uma concretização específica, os rótulos são detectados por espectrometria de massa e a seq³ência da molécula de ácido nucleico é determinada a partir deles. As etapas individuais dos processos podem ser usadas no formato automático, por exemplo, por incorporação em sistemas.
BRPI9707056-4A 1996-01-23 1997-01-23 processos e composições para determinar a seqüência de moléculas de ácido nucleico. BR9707056B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1046296P 1996-01-23 1996-01-23
US58926096A 1996-01-23 1996-01-23
PCT/US1997/001304 WO1997027331A2 (en) 1996-01-23 1997-01-23 Methods and compositions for determining the sequence of nucleic acid molecules

Publications (2)

Publication Number Publication Date
BR9707056A true BR9707056A (pt) 1999-12-28
BR9707056B1 BR9707056B1 (pt) 2009-05-05

Family

ID=26681206

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9707056-4A BR9707056B1 (pt) 1996-01-23 1997-01-23 processos e composições para determinar a seqüência de moléculas de ácido nucleico.

Country Status (17)

Country Link
EP (1) EP0868535B9 (pt)
JP (2) JP2001501449A (pt)
KR (1) KR100482917B1 (pt)
CN (1) CN1163619C (pt)
AT (2) ATE425175T1 (pt)
AU (1) AU717435B2 (pt)
BR (1) BR9707056B1 (pt)
CA (1) CA2243560A1 (pt)
CZ (1) CZ218498A3 (pt)
DE (2) DE69739304D1 (pt)
ES (1) ES2144846T5 (pt)
GR (1) GR3033733T3 (pt)
HU (1) HUP9901321A3 (pt)
NZ (1) NZ331044A (pt)
PL (1) PL328271A1 (pt)
PT (1) PT868535E (pt)
WO (1) WO1997027331A2 (pt)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6401267B1 (en) 1993-09-27 2002-06-11 Radoje Drmanac Methods and compositions for efficient nucleic acid sequencing
DE69701612T2 (de) * 1996-01-23 2000-08-31 Qiagen Genomics, Inc. Verfahren und zusammensetzungen zum analysieren von nukleinsäuremolekulen mittels bemessungstechniken
CN1159452C (zh) * 1996-01-23 2004-07-28 佳根基因组学公司 利用非荧光标记检测配体对结合的方法和组合物
WO1998026095A1 (en) 1996-12-10 1998-06-18 Genetrace Systems Inc. Releasable nonvolatile mass-label molecules
US6060248A (en) * 1997-02-24 2000-05-09 Tm Technologies, Inc. Process for selecting anti-sense oligonucleotides
EP1002128A1 (en) * 1997-07-11 2000-05-24 Brax Genomics Limited Characterising nucleic acids
ES2200355T3 (es) * 1997-07-22 2004-03-01 Qiagen Genomics Inc Metodos y composiciones para analizar acidos nucleicos por espectrometria de masas.
EP1000176A1 (en) * 1997-07-22 2000-05-17 Rapigene, Inc. Computer method and system for correlating sequencing data by ms
GB9718921D0 (en) * 1997-09-05 1997-11-12 Brax Genomics Ltd Catalytically generated mass labels
NZ503289A (en) * 1997-09-15 2002-11-26 Xzillion Gmbh & Co Kg Characterising nucleic acid fragments by mass spectrometry
US6607878B2 (en) 1997-10-06 2003-08-19 Stratagene Collections of uniquely tagged molecules
GB9815163D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds
GB2335035B (en) * 1998-03-03 2003-05-28 Brax Genomics Ltd Screening for functional antisense agents
US6232103B1 (en) 1998-03-23 2001-05-15 Invitrogen Corporation Methods useful for nucleic acid sequencing using modified nucleotides comprising phenylboronic acid
DK1068216T3 (da) 1998-05-15 2004-04-13 Oxford Gene Tech Ip Ltd Bibliotek af oligomerer, der er mærket med forskellige markører
US6074831A (en) * 1998-07-09 2000-06-13 Agilent Technologies, Inc. Partitioning of polymorphic DNAs
US6270976B1 (en) * 1998-09-15 2001-08-07 Brax Group Limited Characterizing nucleic acid by mass spectrometry
US6480791B1 (en) 1998-10-28 2002-11-12 Michael P. Strathmann Parallel methods for genomic analysis
WO2001016090A1 (en) * 1999-08-31 2001-03-08 Qiagen Genomics, Inc. Enantiomerically-enriched compounds having photocleavable bond(s) and methods related thereto
GB0006141D0 (en) 2000-03-14 2000-05-03 Brax Group Ltd Mass labels
US6716634B1 (en) 2000-05-31 2004-04-06 Agilent Technologies, Inc. Increasing ionization efficiency in mass spectrometry
DE10036743A1 (de) * 2000-07-27 2002-02-07 Max Planck Gesellschaft Verfahren zur Bestimmung einer partiellen Nukleotidsequenz eines Nukleinsäuremoleküls
US6706162B1 (en) * 2000-09-25 2004-03-16 Applera Corporation High speed, high resolution compositions, methods, and kits for capillary electrophoresis
EP1950305A1 (en) 2001-05-09 2008-07-30 Monsanto Technology, LLC Tyr a genes and uses thereof
US6613523B2 (en) * 2001-06-29 2003-09-02 Agilent Technologies, Inc. Method of DNA sequencing using cleavable tags
AU2002327236A1 (en) 2001-07-12 2003-01-29 Illumina, Inc. Multiplex nucleic acid reactions
CA2460131C (en) 2001-09-14 2006-11-21 Xzillion Gmbh & Co. Kg Mass labels
US20030165935A1 (en) * 2001-11-21 2003-09-04 Vann Charles S. Digital assay
IL160869A0 (en) * 2004-03-15 2004-08-31 Dnr Imaging System Ltd Integrated system for real time gel electrophoresis running and documenting
DK1740698T3 (da) 2004-04-22 2010-10-25 Talecris Biotherapeutics Inc Rekombinant modificeret plasmin
US20070054345A1 (en) 2004-05-19 2007-03-08 Hunter Christie L Expression quantification using mass spectrometry
WO2006017208A1 (en) * 2004-07-12 2006-02-16 Applera Corporation Mass tags for quantitative analyses
US20070048752A1 (en) 2004-07-12 2007-03-01 Applera Corporation Mass tags for quantitative analyses
US20060183238A1 (en) 2005-02-09 2006-08-17 Applera Corporation Amine-containing compound analysis methods
US7396676B2 (en) 2005-05-31 2008-07-08 Agilent Technologies, Inc. Evanescent wave sensor with attached ligand
GB0515323D0 (en) 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
GB0518585D0 (en) 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
US7501254B2 (en) 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
GB0704764D0 (en) 2007-03-12 2007-04-18 Electrophoretics Ltd Isobarically labelled reagents and methods of their use
US8017403B2 (en) * 2007-06-14 2011-09-13 Quest Diagnostics Investments Incorporated Mass spectrometry method for measuring vitamin B6 in body fluid
HUE024916T2 (en) 2007-11-29 2016-02-29 Grifols Therapeutics Inc Recombinantly modified plasmin
GB0809488D0 (en) 2008-05-23 2008-07-02 Electrophoretics Ltd Mass spectrometric analysis
KR20160110544A (ko) 2008-06-04 2016-09-21 그리폴스 테라퓨틱스 인코포레이티드 플라스민의 제조를 위한 조성물, 방법 및 키트
PL2403865T3 (pl) 2009-03-03 2016-01-29 Grifols Therapeutics Inc Sposoby wytwarzania plazminogenu
MX2012005527A (es) 2009-11-13 2012-08-08 Grifols Therapeutics Inc Preparaciones que contienen el factor de von willebrand (fvw) procedimientos, kits y aplicaciones relacionados con las mismas.
GB0921665D0 (en) 2009-12-10 2010-01-27 Trillion Genomics Ltd Phobes
WO2012003478A2 (en) 2010-07-02 2012-01-05 Ventana Medical Systems, Inc. Detecting targets using mass tags and mass spectrometry
EP2743705B1 (en) 2010-07-23 2016-10-12 Beckman Coulter, Inc. System or method of including analytical units
EP2610243A4 (en) 2010-08-23 2014-04-02 Postech Acad Ind Found Labeling agent and amino acid sequence using same, and method for performing simultaneous quantitative analysis of multiple proteins
KR101207742B1 (ko) 2010-10-14 2012-12-03 포항공과대학교 산학협력단 라벨링제 및 이를 이용한 아미노산 서열 및 단백질 다중 정량 동시 분석방법
CN102140524A (zh) * 2011-03-23 2011-08-03 山东农业大学 多微卫星位点检测试剂盒及检测方法
US9910054B2 (en) 2011-11-07 2018-03-06 Beckman Coulter, Inc. System and method for processing samples
WO2013070754A1 (en) 2011-11-07 2013-05-16 Beckman Coulter, Inc. Robotic arm
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
EP2776843B1 (en) 2011-11-07 2019-03-27 Beckman Coulter, Inc. Centrifuge system and workflow
EP2776846B1 (en) 2011-11-07 2019-08-21 Beckman Coulter, Inc. Aliquotter system and workflow
WO2013093760A2 (en) 2011-12-19 2013-06-27 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
WO2013130487A2 (en) 2012-02-29 2013-09-06 Duke University Novel oxidoreductases for enantioselective reactions
CN103849617A (zh) * 2013-12-16 2014-06-11 复旦大学 用于基因组dna永久保存的接头及方法
GB201322567D0 (en) 2013-12-19 2014-02-05 Electrophoretics Ltd Mass labels
CN103966210B (zh) * 2014-05-29 2016-06-29 江苏省农业科学院 桃ssap分子标记引物组合、分子标记组合及其在桃品种遗传多样性分析上的应用
CN107205353B (zh) 2014-09-26 2021-03-19 谱赛科美国股份有限公司 用于甜菊的单核苷酸多态性(snp)标志物
US10732092B2 (en) 2015-12-22 2020-08-04 University Of Maryland, College Park Analysis of single cell mechanical phenotyping for metastatic detection
US10598594B2 (en) 2015-12-22 2020-03-24 University Of Maryland Cell classification based on mechanical signature of nucleus
WO2017112896A1 (en) 2015-12-22 2017-06-29 Canon U.S. Life Sciences, Inc. System and method of label-free cytometry based on brillouin light scattering
WO2018170436A1 (en) 2017-03-16 2018-09-20 Jacobs Farm Del Cabo Basil with high tolerance to downy mildew
CN106905399B (zh) * 2017-03-27 2019-07-09 武汉大学 一种双链dna b-z构象相互转换的光控方法
JP7396902B2 (ja) * 2017-06-06 2023-12-12 ユニバーシティ オブ メリーランド,カレッジ パーク 転移検出のために単一細胞の機械的フェノタイピングを行う分析
WO2019152391A1 (en) * 2018-01-30 2019-08-08 Rush University Medical Center Sequential staining for multiplex analyses of tissues and cells
CN115667217A (zh) 2020-05-19 2023-01-31 赛本爱尔兰有限公司 氘化的色胺衍生物和使用方法
CN112229892B (zh) * 2020-10-22 2021-09-28 中国科学院化学研究所 一种酚醛树脂组成测试和定量分析方法及应用
CN114984032B (zh) * 2022-06-27 2023-07-07 四川大学 Dna四面体框架核酸-绿原酸复合物及其在制备治疗肝纤维化的药物中的用途
CN115337916B (zh) * 2022-07-29 2023-10-24 福建卫生职业技术学院 一种水凝胶型细胞膜半制备色谱柱及其制备方法与应用
CN117269287A (zh) * 2023-11-20 2023-12-22 中国计量科学研究院 一种喷墨进样-毛细管电泳-质谱联用装置及工作方法
EP4667939A1 (en) 2024-06-21 2025-12-24 Commissariat à l'Energie Atomique et aux Energies Alternatives Multiplex cancer cell profiling using ms-tagged probes containing an iminosydnone cleavable linker
CN119119459B (zh) * 2024-09-05 2025-09-09 河南大学 一种以聚酰胺衍生物为内核的仿生金属酶及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US5346670A (en) * 1986-12-24 1994-09-13 British Technology Group U.S.A. Inc. Phthalocyanine and tetrabenztriazaporphyrin reagents
US5003059A (en) 1988-06-20 1991-03-26 Genomyx, Inc. Determining DNA sequences by mass spectrometry
GB8910880D0 (en) * 1989-05-11 1989-06-28 Amersham Int Plc Sequencing method
GB9208733D0 (en) * 1992-04-22 1992-06-10 Medical Res Council Dna sequencing method
US5565324A (en) * 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
ATE267877T1 (de) * 1993-01-07 2004-06-15 Sequenom Inc Dns - sequenzierung durch massenspektronomie
GB9315847D0 (en) * 1993-07-30 1993-09-15 Isis Innovation Tag reagent and assay method
JPH09505397A (ja) * 1993-11-17 1997-05-27 アマーシャム・インターナショナル・ピーエルシー プライマー伸長質量分光分析による核酸配列決定法
ES2151057T3 (es) * 1994-03-23 2000-12-16 Penn State Res Found Procedimiento para la identificacion de elementos de bibliotecas combinatorias.

Also Published As

Publication number Publication date
ATE425175T1 (de) 2009-03-15
HUP9901321A3 (en) 2001-10-29
EP0868535B2 (en) 2006-01-04
DE69701671D1 (de) 2000-05-18
WO1997027331A2 (en) 1997-07-31
EP0868535A2 (en) 1998-10-07
AU2247397A (en) 1997-08-20
JP2001501449A (ja) 2001-02-06
DE69701671T3 (de) 2006-08-17
CN1163619C (zh) 2004-08-25
BR9707056B1 (pt) 2009-05-05
AU717435B2 (en) 2000-03-23
ES2144846T5 (es) 2006-07-16
WO1997027331A3 (en) 1998-04-02
EP0868535B1 (en) 2000-04-12
DE69739304D1 (de) 2009-04-23
KR100482917B1 (ko) 2005-11-11
CN1212021A (zh) 1999-03-24
KR19990081925A (ko) 1999-11-15
CA2243560A1 (en) 1997-07-31
ES2144846T3 (es) 2000-06-16
HUP9901321A2 (hu) 1999-07-28
NZ331044A (en) 1999-02-25
PL328271A1 (en) 1999-01-18
CZ218498A3 (cs) 1998-12-16
ATE191750T1 (de) 2000-04-15
EP0868535B9 (en) 2007-05-09
PT868535E (pt) 2000-12-29
GR3033733T3 (en) 2000-10-31
JP2008183012A (ja) 2008-08-14
DE69701671T2 (de) 2000-08-10

Similar Documents

Publication Publication Date Title
BR9707056A (pt) Processos e composições para determinar a sequência de moléculas de ácido nucleico
BR0214683A (pt) Molécula de nucleotìdeo ou de nucleosìdeo, métodos de rotular uma molécula de ácido nucléico e para determinar a sequência de um polinucleotìdeo alvo de filamento único, e, kit
AU687801B2 (en) DNA sequencing by mass spectrometry via exonuclease degradation
NO20004962L (no) Fremgangsmåte ved påvisning av nukleinsyrer
DK0699768T3 (da) Fremgangsmåder til quenching i opløsning af fluorescens-mærkede oligonnukleotidprober
DK0397269T3 (da) Fremgangsmåde til syntese af ribonukleinsyre (RNA)
ATE240408T1 (de) Verfahren und verbindungen zur analysierung von nukleinsaeuren durch massenspektrometrie
ATE426045T1 (de) Prozess zur synthetisierung von nukleinsaure
DE69432419D1 (de) Ein elektrochemiluminescenter nachweis von nukleinsäuren auf basis der selbsttragenden sequenzreplikation
BR9707016A (pt) Métodos e composições para analisar moléculas de ácido nuclêico utilizando técnicas dimensionamento.
BR0214119A (pt) Processo de detecção e/ou identificação de sequências de vìrus adenoassociados (aav) e isolamento de novas sequências pelo que identificadas
GR950300047T1 (en) Method and reagent for determining specific nucleotide variations.
DK1159453T3 (da) Fremgangsmåde til direkte nukleinsyresekventering
AU6345700A (en) Derivative nucleic acids and uses thereof
EP1831401A2 (en) Methods, compositions, and kits for forming self-complementary polynucleotides
Monyer et al. Molecular biology and physiology at the single-cell level
ATE242261T1 (de) Fluoreszend-konjugaten von nukleosiden und von nukleotiden, ihrer verfahren zur herstellung und ihrer verwendungen
Bishop et al. The sequence at the 5'terminus of a self-replicating variant of viral Qβ ribonucleic acid
CA2312945A1 (en) Method for identifying nucleic acids by electro-spray mass spectrometry
WO2011070155A1 (en) Rna analytics method
WO2003025567A3 (de) Herstellung von trägergebundenen molekülen mittels oligonucleotid-tags
ATE241701T1 (de) Verfahren zur herstellung von morpholinonukleotiden und verwendung derselben zur analyse und markierung von nukleinsäuresequenzen
BR9800882A (pt) Processos de transcrição in vitro para a separação de produtos naturais e outras substâncias químicas.
Short Screening for novel bioactivities
WO2001040510A3 (de) Dynamische sequenzierung durch hybridisierung

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/05/2009, OBSERVADAS AS CONDICOES LEGAIS.

B24C Patent annual fee: request for for restoration

Free format text: REFERENTE AS 14A, 15A E 16A ANUIDADE.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2195 DE 29/01/2013.

B22O Other matters related to patents and certificates of addition of invention: legal action concerning patent

Free format text: INPI-52400.061596/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO 0132367-62.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: RAPIGENE, INC, WAKANAGA PHARMACEUTICAL CO., LTD, COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, PIG RESEARCH AND DEVELOPMENT CORPORATION, CONNAUGHT LABORATORIES LIMITED, ID BIOMEDICAL CORPOR

B19A Notification of judicial decision: notification of judicial decision

Free format text: INPI-52400.061596/13 SECAO JUDICIARIA DO RIO DE JANEIRO - 13A VARA FEDERAL PROCESSO NO 2013.51.01.132367-3 AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL INPI REU(S): RAPIGENE INC., WAKUNAGA PHARMACEUTICAL CO.LTD., COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, PIG RESEARCH AND DEVELOPMENT CORPORATION, CONNAUGHT LABORATORIES LIMITED E ID BIOMEDICAL CORPORATION DECISAO: ANTE O EXPOSTO: A) JULGO EXTINTO O PROCESSO, SEM RESOLUCAO DE MERITO, COM BASE NO ART. 267, INCISO VI, DO CPC, PELA PERDA DO OBJETO, EM RELACAO AO PEDIDO FORMULADO EM FACE DE RAPIGENE INC., QUANTO A PATENTE PI9707056-4; B) JULGO PROCEDENTE A PRETENSAO DO INPI EM RELACAO A EMPRESA WAKUNAGA PHARMACEUTIC