BR9612750A - Preparado para o transporte de substância ativa através de barreiras - Google Patents
Preparado para o transporte de substância ativa através de barreirasInfo
- Publication number
- BR9612750A BR9612750A BR9612750-3A BR9612750A BR9612750A BR 9612750 A BR9612750 A BR 9612750A BR 9612750 A BR9612750 A BR 9612750A BR 9612750 A BR9612750 A BR 9612750A
- Authority
- BR
- Brazil
- Prior art keywords
- active substance
- prepared
- barriers
- preparation
- transport
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 4
- 230000004888 barrier function Effects 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 abstract 4
- 230000007928 solubilization Effects 0.000 abstract 2
- 238000005063 solubilization Methods 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>"PREPARADO PARA O TRANSPORTE DE SUBSTâNCIA ATIVA ATRAVéS DE BARREIRAS"<D>. Preparado para a plicação da substância ativa na forma das menores gotículas, especialmente com um invólucro membranoso de uma ou de menos camadas de moléculas anfifílicas ou com gotículas de líquido providas de uma substância de veículo anfifílica, especialmente para o transporte da substância ativa para e através de barreiras naturais e constrições, como peles e similares. O preparado não apresenta nenhum ponto de solubilização ou a composição do preparado é largamente afastada do ponto de solubilização com capacidade máxima de permeação. O preparado apresenta um teor de pelo menos dois componentes, que se diferenciam em sua solubilidade no meio de suspensão dos preparados, usualmente água, em pelo menos o fator 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR9612750-3A BR9612750A (pt) | 1994-12-30 | 1996-10-17 | Preparado para o transporte de substância ativa através de barreiras |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4447287A DE4447287C1 (de) | 1994-12-30 | 1994-12-30 | Präparat zum Wirkstofftransport durch Barrieren |
| PCT/EP1996/004526 WO1998017255A1 (de) | 1994-12-30 | 1996-10-17 | Präparat zum wirkstofftransport durch barrieren |
| BR9612750-3A BR9612750A (pt) | 1994-12-30 | 1996-10-17 | Preparado para o transporte de substância ativa através de barreiras |
| CNB961804734A CN1151777C (zh) | 1994-12-30 | 1996-10-17 | 转运活性成分通过屏障的制剂 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9612750A true BR9612750A (pt) | 1999-12-28 |
Family
ID=27179110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9612750-3A BR9612750A (pt) | 1994-12-30 | 1996-10-17 | Preparado para o transporte de substância ativa através de barreiras |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0935457B1 (pt) |
| JP (1) | JP2001502676A (pt) |
| KR (1) | KR100446832B1 (pt) |
| CN (1) | CN1151777C (pt) |
| AT (1) | ATE257373T1 (pt) |
| AU (1) | AU724218B2 (pt) |
| BR (1) | BR9612750A (pt) |
| CA (1) | CA2268670A1 (pt) |
| DE (2) | DE4447287C1 (pt) |
| ES (1) | ES2211984T3 (pt) |
| HU (1) | HUP9903363A3 (pt) |
| MX (1) | MXPA97007996A (pt) |
| WO (1) | WO1998017255A1 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4447287C1 (de) * | 1994-12-30 | 1996-11-07 | Cevc Gregor | Präparat zum Wirkstofftransport durch Barrieren |
| JP4838936B2 (ja) * | 1998-10-23 | 2011-12-14 | イデア アクチェンゲゼルシャフト | 装荷量を改善しおよび脱/会合速度を制御可能とするための、巨大分子と複合凝集体との会合体を開発し、テストし、かつ利用する方法 |
| AU1327000A (en) * | 1998-10-28 | 2000-05-15 | Invitrogen Corporation | Compositions comprising plant cell growth regulating compounds and methods of use thereof |
| HRP20010309B1 (en) * | 1998-12-23 | 2005-06-30 | Idea Ag | Improved formulation for topical non-invasive application in vivo |
| EP1031347B1 (en) * | 1999-01-27 | 2002-04-17 | Idea Ag | Transnasal transport/immunisation with highly adaptable carriers |
| PT1031346E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Vacinacao nao invasiva atraves da pele |
| MXPA02000053A (es) * | 1999-07-05 | 2003-07-21 | Idea Ag | Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables. |
| WO2001041738A2 (en) * | 1999-12-10 | 2001-06-14 | Celator Technologies Inc. | Lipid carrier compositions with protected surface reactive functions |
| US20040105881A1 (en) | 2002-10-11 | 2004-06-03 | Gregor Cevc | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
| PT1551370E (pt) * | 2002-10-11 | 2008-02-07 | Idea Ag | Agregado com capacidade de deformação aumentada, que compreende pelo menos três anfipáticos, para o transporte melhorado através de barreiras semi-permeáveis e para a aplicação de fármaco não invasiva in vivo, especialmente através da pele |
| EP1585548B1 (en) * | 2002-12-09 | 2018-06-27 | Abraxis BioScience, LLC | Compositions and methods of delivery of pharmacological agents |
| DE102008034098A1 (de) | 2008-07-21 | 2010-02-04 | Lts Lohmann Therapie-Systeme Ag | Zubereitung und lontophoretische Vorrichtung für die transdermale Anwendung von Wirkstoffen |
| CN105434353A (zh) | 2009-06-03 | 2016-03-30 | 斯昆申技术控股有限责任公司 | 用于治疗深部组织疼痛的制剂 |
| DE112010003355T5 (de) | 2009-08-21 | 2012-07-12 | Targeted Delivery Technologies Ltd. | Veskuläre Formulierungen |
| WO2013057208A1 (en) | 2011-10-18 | 2013-04-25 | Targeted Delivery Technologies Limited | Compositions and methods for reducing the proliferation and viability of microbial agents |
| CN102579350B (zh) * | 2012-03-02 | 2013-04-24 | 海南灵康制药有限公司 | 右旋布洛芬脂质体固体制剂 |
| GB201205642D0 (en) | 2012-03-29 | 2012-05-16 | Sequessome Technology Holdings Ltd | Vesicular formulations |
| PT3316857T (pt) | 2015-06-30 | 2021-11-03 | Sequessome Tech Holdings Limited | Composições multifásicas |
| CH713023A2 (de) * | 2016-10-11 | 2018-04-13 | Kuhs Bernd | Verfahren zur Herstellung von dermatologischen und kosmetischen Präparaten mit ausgeprägten lamellaren Strukturen unter Verwendung von Phosphatidylcholin und biologischen Zellmaterialien, welche durch die Einwirkung von Ultraschallwellen aufgeschlossen werden und gleichzeitig zwischen den lamellaren Strukturen eingelagert werden. |
| WO2019023247A1 (en) | 2017-07-25 | 2019-01-31 | Immutics, Inc. | TREATMENT OF CANCER BY BLOCKING THE INTERACTION OF TIM-3 AND ITS LIGAND |
| CN116063505B (zh) | 2019-01-30 | 2024-05-03 | 真和制药有限公司 | 抗gal3抗体及其用途 |
| CN110101591B (zh) * | 2019-05-23 | 2022-01-18 | 广州科斯曼生物科技有限公司 | 一种长效保湿组合物及其制备方法和应用 |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4921706A (en) * | 1984-11-20 | 1990-05-01 | Massachusetts Institute Of Technology | Unilamellar lipid vesicles and method for their formation |
| DE3542773A1 (de) * | 1985-12-04 | 1987-06-11 | Roehm Pharma Gmbh | Hautwirksame pharmaka mit liposomen als wirkstofftraeger |
| US5064655A (en) * | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
| FR2649155B1 (fr) * | 1989-06-28 | 1991-09-13 | Elf Aquitaine | Dispositif de mesure dynamometrique pour tige de forage |
| JP2844756B2 (ja) * | 1989-12-01 | 1999-01-06 | 日本新薬株式会社 | 脂肪乳剤 |
| WO1992003122A1 (de) * | 1990-08-24 | 1992-03-05 | Gregor Cevc | Präparat zur wirkstoffapplikation in kleinsttröpfchenform |
| SE9003100D0 (sv) * | 1990-09-28 | 1990-09-28 | Kabivitrum Ab | Lipid formulation system |
| SE9200952D0 (sv) * | 1992-03-27 | 1992-03-27 | Kabi Pharmacia Ab | Pharmaceutical carrier system containing defined lipids |
| SE9200951D0 (sv) * | 1992-03-27 | 1992-03-27 | Kabi Pharmacia Ab | Pharmaceutical composition containing a defined lipid system |
| FR2714601B1 (fr) * | 1993-12-30 | 1996-02-09 | Oreal | Composition dépigmentante pour le traitement simultané des couches superficielles et profondes, son utilisation. |
| JPH0881360A (ja) * | 1994-07-13 | 1996-03-26 | Wakamoto Pharmaceut Co Ltd | 安定な脂肪乳剤 |
| ATE223202T1 (de) * | 1994-09-30 | 2002-09-15 | Mika Pharma Ges Fuer Die Entwi | Pharmazeutische zusammensetzung |
| IT1270678B (it) * | 1994-10-20 | 1997-05-07 | Bayer Ag | Liposomi al chetoprofen |
| DE4447287C1 (de) * | 1994-12-30 | 1996-11-07 | Cevc Gregor | Präparat zum Wirkstofftransport durch Barrieren |
-
1994
- 1994-12-30 DE DE4447287A patent/DE4447287C1/de not_active Revoked
-
1996
- 1996-10-17 KR KR10-1999-7003375A patent/KR100446832B1/ko not_active Expired - Fee Related
- 1996-10-17 MX MXPA97007996A patent/MXPA97007996A/es not_active IP Right Cessation
- 1996-10-17 HU HU9903363A patent/HUP9903363A3/hu unknown
- 1996-10-17 EP EP96934737A patent/EP0935457B1/de not_active Revoked
- 1996-10-17 AT AT96934737T patent/ATE257373T1/de not_active IP Right Cessation
- 1996-10-17 ES ES96934737T patent/ES2211984T3/es not_active Expired - Lifetime
- 1996-10-17 CN CNB961804734A patent/CN1151777C/zh not_active Expired - Fee Related
- 1996-10-17 WO PCT/EP1996/004526 patent/WO1998017255A1/de not_active Ceased
- 1996-10-17 AU AU45108/97A patent/AU724218B2/en not_active Ceased
- 1996-10-17 JP JP10518859A patent/JP2001502676A/ja active Pending
- 1996-10-17 DE DE59610889T patent/DE59610889D1/de not_active Expired - Lifetime
- 1996-10-17 CA CA002268670A patent/CA2268670A1/en not_active Abandoned
- 1996-10-17 BR BR9612750-3A patent/BR9612750A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100446832B1 (ko) | 2004-09-04 |
| CN1151777C (zh) | 2004-06-02 |
| AU724218B2 (en) | 2000-09-14 |
| HUP9903363A3 (en) | 2008-04-28 |
| DE59610889D1 (de) | 2004-02-12 |
| AU4510897A (en) | 1998-05-15 |
| ES2211984T3 (es) | 2004-07-16 |
| JP2001502676A (ja) | 2001-02-27 |
| DE4447287C1 (de) | 1996-11-07 |
| ATE257373T1 (de) | 2004-01-15 |
| CN1234736A (zh) | 1999-11-10 |
| HK1021622A1 (en) | 2000-06-23 |
| WO1998017255A1 (de) | 1998-04-30 |
| MXPA97007996A (es) | 2004-03-15 |
| CA2268670A1 (en) | 1998-04-30 |
| KR20000049266A (ko) | 2000-07-25 |
| EP0935457B1 (de) | 2004-01-07 |
| HUP9903363A2 (hu) | 2000-03-28 |
| EP0935457A1 (de) | 1999-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 14A E 15A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 14A E 15A ANUIDADES. |