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BR9611300A - Derivados de tropano em fusão suas preparações e uso - Google Patents

Derivados de tropano em fusão suas preparações e uso

Info

Publication number
BR9611300A
BR9611300A BR9611300A BR9611300A BR9611300A BR 9611300 A BR9611300 A BR 9611300A BR 9611300 A BR9611300 A BR 9611300A BR 9611300 A BR9611300 A BR 9611300A BR 9611300 A BR9611300 A BR 9611300A
Authority
BR
Brazil
Prior art keywords
alkyl
alkynyl
alkenyl
aryl
arylalkyl
Prior art date
Application number
BR9611300A
Other languages
English (en)
Inventor
Jorgen Scheel-Kruger
Gunnar M Olsen
Elsebet Ostergaard Nielsen
Bjarne Hugo Dahl
Leif Helth Jensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of BR9611300A publication Critical patent/BR9611300A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Exhaust Gas After Treatment (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR9611300A 1995-11-02 1996-11-04 Derivados de tropano em fusão suas preparações e uso BR9611300A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK122395 1995-11-02
DK14696 1996-02-13

Publications (1)

Publication Number Publication Date
BR9611300A true BR9611300A (pt) 1999-06-15

Family

ID=26063395

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9611300A BR9611300A (pt) 1995-11-02 1996-11-04 Derivados de tropano em fusão suas preparações e uso

Country Status (24)

Country Link
US (1) US5998405A (pt)
EP (1) EP0858461B1 (pt)
JP (1) JP3157839B2 (pt)
KR (1) KR100277482B1 (pt)
CN (1) CN1060775C (pt)
AT (1) ATE224392T1 (pt)
AU (1) AU702720B2 (pt)
BR (1) BR9611300A (pt)
CA (1) CA2236707C (pt)
CZ (1) CZ285571B6 (pt)
DE (1) DE69623799T2 (pt)
DK (1) DK0858461T3 (pt)
EE (1) EE03566B1 (pt)
HU (1) HUP9802534A3 (pt)
IL (1) IL123898A (pt)
IS (1) IS4708A (pt)
NO (1) NO309569B1 (pt)
NZ (1) NZ321970A (pt)
PL (1) PL184843B1 (pt)
RU (1) RU2162469C2 (pt)
SK (1) SK282944B6 (pt)
TR (1) TR199800780T2 (pt)
UA (1) UA47442C2 (pt)
WO (1) WO1997016451A1 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329520B1 (en) * 1990-08-09 2001-12-11 Research Triangle Institute Cocaine receptor binding ligands
US6706880B2 (en) 1990-08-09 2004-03-16 Research Triangle Institute Cocaine receptor binding ligands
US6150376A (en) * 1998-08-05 2000-11-21 Georgetown University Bi- and tri-cyclic aza compounds and their uses
HUP0103203A3 (en) * 1998-08-18 2002-10-28 Ucb Sa Azaadamantane derivatives and pharmaceutical compositions thereof
AU7723300A (en) 1999-09-27 2001-04-30 Georgetown University Novel tropane analogs
US6479509B1 (en) 2000-05-22 2002-11-12 Research Triangle Institute Method of promoting smoking cessation
WO2002002559A1 (en) * 2000-07-04 2002-01-10 Neurosearch A/S Steric isomers of fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
EP1379269B1 (en) 2001-04-09 2009-03-04 Neurosearch A/S Adenosine a2a receptor antagonists combined with neurotrophic activity compounds in the treatment of parkinson's disease
WO2002094827A1 (en) * 2001-05-23 2002-11-28 Neurosearch A/S Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
AR035898A1 (es) 2001-05-25 2004-07-21 Wyeth Corp Aril-8-azabiciclo[3.2.1]octanos, un proceso para su preparacion, una formulacion y el uso de dichos compuestos para la manufactura de un medicamento para el tratamiento de la depresion
WO2003045388A1 (en) * 2001-11-30 2003-06-05 Neurosearch A/S Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
AU2004212165B2 (en) 2003-02-12 2010-02-18 Neurosearch A/S Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
ES2335664T3 (es) 2003-02-12 2010-03-31 Neurosearch A/S Derivados de 8-aza-biciclo(3.2.1)octano y su uso como inhibidores de la reabsorcion de neurotransmisores de monoaminas.
CN100356940C (zh) * 2004-12-01 2007-12-26 蒋毅 制备大叶蒟提取物的方法、提取物及其应用
JP2008534653A (ja) 2005-04-08 2008-08-28 ノイロサーチ アクティーゼルスカブ 新規エナンチオマー及びモノアミン神経伝達物質再取り込み阻害剤としてのそれらの使用
US7943630B2 (en) 2005-06-28 2011-05-17 Neurosearch A/S 3,9-diaza-spiro[5.5]undecane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US8093388B2 (en) 2005-06-28 2012-01-10 Neurosearch A/S 3-aza spiro[5,5]undec-8-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
JP2009504773A (ja) * 2005-08-19 2009-02-05 エラン ファーマシューティカルズ，インコーポレイテッド ガンマセクレターゼの架橋ｎ−二環式スルホンアミド阻害剤
TW200800980A (en) 2006-02-17 2008-01-01 Neurosearch As Novel compounds
CA2760981A1 (en) 2009-05-15 2010-11-18 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
KR20120044978A (ko) * 2009-06-19 2012-05-08 아보트 러보러터리즈 디아자호모아다만탄 유도체 및 이들의 사용 방법
WO2011032903A1 (en) 2009-09-21 2011-03-24 Neurosearch A/S Piperazinyl-alkyl-benzoimidazol-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US20130040985A1 (en) 2010-01-29 2013-02-14 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
WO2011117289A1 (en) 2010-03-25 2011-09-29 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neuro-transmitter re-uptake inhibitors
WO2012000881A1 (en) 2010-07-02 2012-01-05 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
JP6052524B1 (ja) * 2015-07-30 2016-12-27 秋夫 湯田 持ち運び設置が容易な手提げハンドルの付いた薪ストーブ。
CA3259792A1 (en) 2022-07-08 2024-01-11 Initiator Pharma A/S COMPOUND FOR THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION
CN120129523A (zh) 2022-10-28 2025-06-10 创始人制药股份有限公司 用于治疗疼痛的化合物
EP4646204A1 (en) 2023-01-03 2025-11-12 Initiator Pharma A/S Compound for treatment of erectile dysfunction
WO2025051846A1 (en) 2023-09-05 2025-03-13 Initiator Pharma A/S Compound for treatment of female sexual dysfunction
KR20250050681A (ko) 2023-10-08 2025-04-15 임종완 이중관형멀티커넥터

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672644B2 (en) * 1992-12-23 1996-10-10 Neurosearch A/S Aryl substituted heterocyclic compounds
UA49801C2 (uk) * 1994-04-19 2002-10-15 Нейросерч А/С Похідні тропан-2-альдоксиму, спосіб їх отримання, фармацевтична композиція, спосіб лікування

Also Published As

Publication number Publication date
AU702720B2 (en) 1999-03-04
NO309569B1 (no) 2001-02-19
MX9803554A (es) 1998-09-30
EE03566B1 (et) 2001-12-17
NZ321970A (en) 2000-02-28
SK42298A3 (en) 1998-10-07
NO981609D0 (no) 1998-04-07
US5998405A (en) 1999-12-07
CN1201461A (zh) 1998-12-09
DE69623799T2 (de) 2003-01-30
IL123898A (en) 2001-08-08
KR100277482B1 (ko) 2001-01-15
EP0858461B1 (en) 2002-09-18
CA2236707A1 (en) 1997-05-09
PL326448A1 (en) 1998-09-28
AU7563196A (en) 1997-05-22
CN1060775C (zh) 2001-01-17
HK1016984A1 (en) 1999-11-12
HUP9802534A2 (hu) 1999-04-28
CZ285571B6 (cs) 1999-09-15
ATE224392T1 (de) 2002-10-15
KR19990064111A (ko) 1999-07-26
CA2236707C (en) 2002-08-06
DE69623799D1 (de) 2002-10-24
WO1997016451A1 (en) 1997-05-09
JPH11514638A (ja) 1999-12-14
EE9800100A (et) 1998-10-15
SK282944B6 (sk) 2003-01-09
UA47442C2 (uk) 2002-07-15
EP0858461A1 (en) 1998-08-19
RU2162469C2 (ru) 2001-01-27
PL184843B1 (pl) 2002-12-31
HUP9802534A3 (en) 1999-06-28
JP3157839B2 (ja) 2001-04-16
DK0858461T3 (da) 2003-01-27
CZ113898A3 (cs) 1998-07-15
TR199800780T2 (xx) 1998-07-21
IL123898A0 (en) 1998-10-30
IS4708A (is) 1998-03-31
NO981609L (no) 1998-06-26

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Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
FA8 Dismissal: dismissal - article 36, par. 1 of industrial property law