[go: up one dir, main page]

BR9610790A - Formulações de gel contendo fatores de crescimento - Google Patents

Formulações de gel contendo fatores de crescimento

Info

Publication number
BR9610790A
BR9610790A BR9610790A BR9610790A BR9610790A BR 9610790 A BR9610790 A BR 9610790A BR 9610790 A BR9610790 A BR 9610790A BR 9610790 A BR9610790 A BR 9610790A BR 9610790 A BR9610790 A BR 9610790A
Authority
BR
Brazil
Prior art keywords
gel formulations
growth factors
gel
formulations containing
containing growth
Prior art date
Application number
BR9610790A
Other languages
English (en)
Inventor
John Cini
Amy Finkenaur
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of BR9610790A publication Critical patent/BR9610790A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1808Epidermal growth factor [EGF] urogastrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Colloid Chemistry (AREA)
BR9610790A 1995-10-06 1996-09-24 Formulações de gel contendo fatores de crescimento BR9610790A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/539,898 US5705485A (en) 1987-09-18 1995-10-06 Gel formulations containing growth factors
PCT/US1996/015288 WO1997012601A2 (en) 1995-10-06 1996-09-24 Gel formulations containing growth factors

Publications (1)

Publication Number Publication Date
BR9610790A true BR9610790A (pt) 1999-07-13

Family

ID=24153118

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9610790A BR9610790A (pt) 1995-10-06 1996-09-24 Formulações de gel contendo fatores de crescimento

Country Status (19)

Country Link
US (1) US5705485A (pt)
EP (1) EP0859596B1 (pt)
JP (1) JP4001382B2 (pt)
KR (1) KR100444417B1 (pt)
CN (1) CN1142791C (pt)
AT (1) ATE209900T1 (pt)
AU (1) AU706806B2 (pt)
BR (1) BR9610790A (pt)
CA (1) CA2234235C (pt)
CZ (1) CZ294676B6 (pt)
DE (1) DE69617723T2 (pt)
DK (1) DK0859596T3 (pt)
ES (1) ES2167611T3 (pt)
HU (1) HU223880B1 (pt)
NO (1) NO981539L (pt)
PL (1) PL187174B1 (pt)
PT (1) PT859596E (pt)
WO (1) WO1997012601A2 (pt)
ZA (1) ZA968398B (pt)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6636098A (en) * 1998-03-07 1999-09-20 Dae Woong Pharmaceutical Co., Ltd. Topical composition containing human epidermal growth factor
US20030147860A1 (en) 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
WO2000013710A2 (en) * 1998-09-04 2000-03-16 Scios Inc. Hydrogel compositions for the controlled release administration of growth factors
US6057280A (en) 1998-11-19 2000-05-02 Huish Detergents, Inc. Compositions containing α-sulfofatty acid esters and methods of making and using the same
DE19925519A1 (de) 1999-06-04 2000-12-07 Lohmann Therapie Syst Lts Wundauflage zur gesteuerten Abgabe von Wirkstoff an Wunden und Verfahren zu ihrer Herstellung
WO2000078358A2 (en) * 1999-06-18 2000-12-28 The Collaborative Group, Ltd. Hyaluronic acid microspheres for sustained gene transfer
US8188043B2 (en) * 1999-07-28 2012-05-29 The Board Of Trustees Of The Leland Stanford Jr. University Nicotine in therapeutic angiogenesis and vasculogenesis
WO2001034214A1 (en) 1999-11-09 2001-05-17 Denki Kagaku Kogyo Kabushiki Kaisha Use of soluble cellulose derivative having been made hardly soluble in water and process for producing the same
DE10048260A1 (de) * 2000-09-29 2002-04-11 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Aminoguanidin und/oder dessen Derivaten und Strukturanaloga zur Hautaufhellung von Altersflecken und/oder zur Verhinderung der Hautbräunung, insbesondere der durch UV-Strahlung hervorgerufenen Hautbräunung
US6703039B2 (en) * 2000-12-06 2004-03-09 Bausch & Lomb Incorporated Reversible gelling system for ocular drug delivery
JP4434584B2 (ja) * 2001-01-26 2010-03-17 ジェネティックス ファーマシューティカルズ, インク. 血管新生を促進する方法及び組成物
DE10140623A1 (de) * 2001-08-18 2003-03-06 Nawa Heilmittel Gmbh Pharmazeutisches Präparat zur Behandlung von Wunden
US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US7037504B2 (en) * 2001-10-23 2006-05-02 Waratah Pharmaceuticals, Inc. Epidermal growth factor protein and gene, and methods of use therefor
US20080086792A1 (en) 2006-10-13 2008-04-17 Thomas Charles Kuracina Method and apparatus for diverting sweat, liquid, moisture or the like from an eye
US7303814B2 (en) 2002-02-21 2007-12-04 Encelle, Inc. Immobilized bioactive hydrogel matrices as surface coatings
US20030220632A1 (en) * 2002-05-23 2003-11-27 Wolfgang Strasser Method of using gel sheets for laser treatment
ATE497778T1 (de) 2002-09-16 2011-02-15 Agennix Inc Lactoferrin-zusammensetzungen und verfahren zur behandlung von diabetischen ulcus
ATE444732T1 (de) * 2003-08-07 2009-10-15 Allergan Inc Zusammensetzungen zur abgabe von therapeutika in die augen und verfahren zu ihrer herstellung und verwendung
ATE497379T1 (de) 2003-12-11 2011-02-15 Teikoku Pharma Usa Inc Verfahren und zusammensetzungen für die behandlung von hautwunden
CN100411615C (zh) * 2003-12-12 2008-08-20 上海第二医科大学附属瑞金医院 氨基胍对难愈创面的防治作用
WO2005077402A1 (en) * 2004-02-11 2005-08-25 Virchow Biotech Private Limited Honey based gel formulations
US20060036211A1 (en) * 2004-07-29 2006-02-16 X-Sten, Inc. Spinal ligament modification kit
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
EP1812022B1 (en) 2004-09-28 2014-01-15 Atrium Medical Corporation Stand-alone film and methods for making the same
JP2008546707A (ja) * 2005-06-17 2008-12-25 ジェネンテック・インコーポレーテッド 創傷治癒
WO2007013100A1 (en) * 2005-07-26 2007-02-01 Virchow Biotech Private Limited Gel formulation comprising platelet derived growth factor
US20070055263A1 (en) * 2005-07-29 2007-03-08 X-Sten Corp. Tools for Percutaneous Spinal Ligament Decompression and Device for Supporting Same
ES2637638T3 (es) * 2005-07-29 2017-10-16 Vertos Medical, Inc. Dispositivos de extirpación de tejido percutáneo
FR2891149B1 (fr) * 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
US9278161B2 (en) * 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
DE102005055275A1 (de) * 2005-11-17 2007-05-24 Ursapharm Arzneimittel Gmbh & Co. Kg Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung
KR100687281B1 (ko) * 2005-11-30 2007-02-27 한국과학기술연구원 생리 활성 물질이 결합된 조직 재생용 주입형 온도 감응성플루로닉 유도체 하이드로겔 및 이의 제조 방법
KR100742313B1 (ko) * 2006-03-21 2007-07-24 퓨리메드 주식회사 신규한 혈소판 유래 성장 인자(pdgf) b 폴리펩타이드및 이의 유전자
US7942830B2 (en) 2006-05-09 2011-05-17 Vertos Medical, Inc. Ipsilateral approach to minimally invasive ligament decompression procedure
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
EP2090314A4 (en) * 2006-10-26 2010-01-13 Senju Pharma Co AQUEOUS LIQUID OPHTHALMIC PREPARATION
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
US20080221383A1 (en) * 2007-02-12 2008-09-11 Vertos Medical, Inc. Tissue excision devices and methods
US20090118709A1 (en) * 2007-11-06 2009-05-07 Vertos Medical, Inc. A Delaware Corporation Tissue Excision Tool, Kits and Methods of Using the Same
JP5582711B2 (ja) * 2008-09-25 2014-09-03 株式会社エー・アイ・システムプロダクト ローション状の塗薬
USD619252S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
USD610259S1 (en) 2008-10-23 2010-02-16 Vertos Medical, Inc. Tissue modification device
USD619253S1 (en) 2008-10-23 2010-07-06 Vertos Medical, Inc. Tissue modification device
USD611146S1 (en) 2008-10-23 2010-03-02 Vertos Medical, Inc. Tissue modification device
USD621939S1 (en) 2008-10-23 2010-08-17 Vertos Medical, Inc. Tissue modification device
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
EP2480204B1 (en) * 2009-09-22 2013-11-06 Vlife Sciences Technologies Pvt Ltd. Topical formulation for diabetic foot ulcers
EP2593141B1 (en) 2010-07-16 2018-07-04 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
EP2729219A4 (en) * 2011-07-06 2015-04-01 Orf Líftaekni Hf METHOD OF USING NON-VEGETABLE GROWTH FACTOR STABILIZED FOR SKIN CARE
CA2854160A1 (en) 2011-11-02 2013-05-10 Halscion, Inc. Methods and compositions for wound treatment
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US9422497B2 (en) 2012-09-21 2016-08-23 Exxonmobil Research And Engineering Company Synthetic lubricant basestocks and methods of preparation thereof
EP2968462B1 (en) 2013-03-15 2020-12-23 The Jackson Laboratory Methods for promoting wound healing and hair growth
US10160793B2 (en) 2013-03-15 2018-12-25 Genentech, Inc. Methods of treating inflammatory bowel disease using IL-22 Fc fusion proteins
US9675537B2 (en) 2014-06-30 2017-06-13 Johnson & Johnson Consumer Inc. Hair growth composition and method
MX2017004520A (es) * 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
WO2017035280A1 (en) * 2015-08-24 2017-03-02 Nugene, Inc. Skin damage healing aids and dressings
US20190070299A1 (en) * 2016-02-23 2019-03-07 Matripharm International Inc. Dual-rate release formulation with high drug loading
PT3509506T (pt) 2016-09-07 2021-05-04 Vertos Medical Inc Instrumentos de ressecção percutânea de recesso lateral
WO2018213795A1 (en) * 2017-05-18 2018-11-22 The Board Of Trustees Of The Leland Stanford Junior University Targeted in situ therapeutic delivery of secreted factors from stem cells for treatment of damaged tissue
MX2020007628A (es) 2018-01-26 2020-10-12 Genentech Inc Composiciones y metodos de uso.
TWI835772B (zh) 2018-01-26 2024-03-21 美商建南德克公司 Il-22fc融合蛋白及使用方法
CN111757751A (zh) 2018-02-21 2020-10-09 豪夫迈·罗氏有限公司 用于使用IL-22 Fc融合蛋白的治疗的剂量方案
CN114601959A (zh) * 2020-11-23 2022-06-10 山东融元康医疗科技有限公司 一种医用皮肤护理敷料及其制备方法和应用
WO2023245144A1 (en) 2022-06-16 2023-12-21 Vertos Medical, Inc. Integrated instrument assembly

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190361B (it) * 1985-05-30 1988-02-16 Zambon Spa Composizione farmaceutica in crema per uso dermale ed oftalmico
NZ235556A (en) * 1986-11-05 1991-06-25 Ethicon Inc Breast milk substitute containing recombinant human egf
US4717717A (en) * 1986-11-05 1988-01-05 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
US5124316A (en) * 1986-11-14 1992-06-23 President And Fellows Of Harvard College Method for periodontal regeneration
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
ES2094359T3 (es) * 1991-06-21 1997-01-16 Genetics Inst Formulaciones farmaceuticas de proteinas osteogenicas.
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
WO1993008825A1 (en) * 1991-11-04 1993-05-13 Zymogenetics, Inc. Pdgf gel formulation
JP3102655B2 (ja) * 1991-12-27 2000-10-23 住友製薬株式会社 超音波制御による薬物放出製剤

Also Published As

Publication number Publication date
DE69617723T2 (de) 2002-05-08
NO981539L (no) 1998-06-02
CN1211191A (zh) 1999-03-17
HUP9803002A3 (en) 2001-08-28
WO1997012601A3 (en) 1997-05-01
DE69617723D1 (de) 2002-01-17
PL326064A1 (en) 1998-08-17
HUP9803002A2 (hu) 1999-04-28
WO1997012601A2 (en) 1997-04-10
JP4001382B2 (ja) 2007-10-31
CZ294676B6 (cs) 2005-02-16
EP0859596A2 (en) 1998-08-26
AU706806B2 (en) 1999-06-24
KR19990064041A (ko) 1999-07-26
KR100444417B1 (ko) 2004-11-03
ES2167611T3 (es) 2002-05-16
ATE209900T1 (de) 2001-12-15
US5705485A (en) 1998-01-06
HU223880B1 (hu) 2005-02-28
CA2234235A1 (en) 1997-04-10
PL187174B1 (pl) 2004-05-31
EP0859596B1 (en) 2001-12-05
AU7370796A (en) 1997-04-28
CZ102498A3 (cs) 1999-08-11
JPH11512740A (ja) 1999-11-02
CN1142791C (zh) 2004-03-24
ZA968398B (en) 1998-04-06
CA2234235C (en) 2002-05-14
DK0859596T3 (da) 2002-03-04
NO981539D0 (no) 1998-04-03
PT859596E (pt) 2002-05-31

Similar Documents

Publication Publication Date Title
BR9610790A (pt) Formulações de gel contendo fatores de crescimento
EP0383363A3 (en) Use of wound healing agents
EP1563844A3 (en) Wound healing formulations containing human plasma fibronectin
DE68926051D1 (de) Polypeptid-polymer-konjugate mit wundheilender wirkung
PT777482E (pt) Composicao de combinacao para utilizacao em doencas imunologicas
ATE135216T1 (de) Verwendung von spiperone-derivate zur immunosuppression
ES2183220T3 (es) Curacion de heridas y tratamientos de la fibrosis.
ES2065696T3 (es) Composicion farmaceutica.
DK0951294T3 (da) Sårhelende formuleringer indeholdende humanplasmafibronectin
DE68905076D1 (de) Pharmazeutische zusammensetzung fuer die behandlung von hautwunden.
BG96495A (en) Aplication of - interferon for the treatment of wounds in autommune vasculitis

Legal Events

Date Code Title Description
PC Transfer

Free format text: JOHNSON & JOHNSON (US)

FB36 Technical and formal requirements: requirement - article 36 of industrial property law
HJEG Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/09/1996, OBSERVADAS AS CONDICOES LEGAIS.

B24C Patent annual fee: request for for restoration

Free format text: REFERENTE 12A. 13A. E 14A. ANUIDADE(S).

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE DESPACHO 24.3, PUBLICADO NA RPI 2108 DE 31/05/2011.