BR9610385A - Novas 4-(oxalcoxifenil)-3-óxi-piperidinas para tratamento de insuficiência cardiáca e renal - Google Patents

Novas 4-(oxalcoxifenil)-3-óxi-piperidinas para tratamento de insuficiência cardiáca e renal

Info

Publication number: BR9610385A
Authority: BR; Brazil
Prior art keywords: oxalcoxyphenyl; piperidines; oxy; heart; treatment
Prior art date: 1995-09-07

Application number

BR9610385A

Other languages

English (en)

Inventor

Alfred Binggeli

Volker Breu

Daniel Bur

Walter Fischli

Rolf Gueller

Georges Hirth

Hans-Peter Maerki

Marcel Mueller

Christian Oefner

Heinz Stadler

Eric Vieira

Maurice Wilhelm

Wolfgang Wostl

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-07

Filing date

1996-08-29

Publication date

1999-07-06

1996-08-29 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1999-07-06 Publication of BR9610385A publication Critical patent/BR9610385A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Reproductive Health (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

BR9610385A 1995-09-07 1996-08-29 Novas 4-(oxalcoxifenil)-3-óxi-piperidinas para tratamento de insuficiência cardiáca e renal BR9610385A (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
CH254895		1995-09-07
CH187696		1996-07-26
PCT/EP1996/003803 WO1997009311A1 (de)	1995-09-07	1996-08-29	Neue 4-(oxyalkoxyphenyl)-3-oxy-piperidine zur behandlung von herz- und niereninsuffizienz

Publications (1)

Publication Number	Publication Date
BR9610385A true BR9610385A (pt)	1999-07-06

Family

ID=25688898

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9610385A BR9610385A (pt)	1995-09-07	1996-08-29	Novas 4-(oxalcoxifenil)-3-óxi-piperidinas para tratamento de insuficiência cardiáca e renal

Country Status (26)

Country	Link
US (2)	US6051712A (pt)
EP (1)	EP0863875B1 (pt)
JP (1)	JP3648251B2 (pt)
KR (1)	KR100384979B1 (pt)
CN (1)	CN1256326C (pt)
AT (1)	ATE242213T1 (pt)
BR (1)	BR9610385A (pt)
CA (1)	CA2230931C (pt)
CY (1)	CY2488B1 (pt)
CZ (1)	CZ292327B6 (pt)
DE (1)	DE59610509D1 (pt)
DK (1)	DK0863875T3 (pt)
ES (1)	ES2201192T3 (pt)
HU (1)	HUP9900926A3 (pt)
IL (1)	IL123293A (pt)
MA (1)	MA23967A1 (pt)
MY (1)	MY121967A (pt)
NO (1)	NO310069B1 (pt)
NZ (1)	NZ315677A (pt)
PL (1)	PL193686B1 (pt)
PT (1)	PT863875E (pt)
RU (1)	RU2167865C2 (pt)
SA (1)	SA96170317B1 (pt)
TR (1)	TR199800409T1 (pt)
TW (1)	TW474932B (pt)
WO (1)	WO1997009311A1 (pt)

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1996
- 1996-08-29 CZ CZ1998684A patent/CZ292327B6/cs not_active IP Right Cessation
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- 1996-08-29 WO PCT/EP1996/003803 patent/WO1997009311A1/de not_active Ceased
- 1996-08-29 TR TR1998/00409T patent/TR199800409T1/xx unknown
- 1996-08-29 DK DK96927715T patent/DK0863875T3/da active
- 1996-08-29 PT PT96927715T patent/PT863875E/pt unknown
- 1996-08-29 DE DE59610509T patent/DE59610509D1/de not_active Expired - Lifetime
- 1996-08-29 CN CNB961976748A patent/CN1256326C/zh not_active Expired - Fee Related
- 1996-08-29 KR KR10-1998-0701707A patent/KR100384979B1/ko not_active Expired - Fee Related
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- 1996-09-24 SA SA96170317A patent/SA96170317B1/ar unknown
1998
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1999
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Also Published As

Publication number	Publication date
CA2230931A1 (en)	1997-03-13
DE59610509D1 (de)	2003-07-10
HK1016177A1 (en)	1999-10-29
US6150526A (en)	2000-11-21
NO980954D0 (no)	1998-03-05
HUP9900926A2 (hu)	1999-09-28
US6051712A (en)	2000-04-18
SA96170317B1 (ar)	2006-05-13
KR100384979B1 (ko)	2003-10-17
CA2230931C (en)	2009-05-19
MX9801814A (es)	1998-08-30
CZ292327B6 (cs)	2003-09-17
JPH11500447A (ja)	1999-01-12
EP0863875B1 (de)	2003-06-04
NZ315677A (en)	2000-02-28
AU708616B2 (en)	1999-08-05
CY2488B1 (en)	2005-06-03
HUP9900926A3 (en)	2002-12-28
TR199800409T1 (xx)	1998-05-21
TW474932B (en)	2002-02-01
CZ68498A3 (cs)	1998-10-14
PT863875E (pt)	2003-10-31
AU6743296A (en)	1997-03-27
NO310069B1 (no)	2001-05-14
MA23967A1 (fr)	1997-04-01
NO980954L (no)	1998-04-28
EP0863875A1 (de)	1998-09-16
WO1997009311A1 (de)	1997-03-13
PL193686B1 (pl)	2007-03-30
JP3648251B2 (ja)	2005-05-18
CN1256326C (zh)	2006-05-17
ATE242213T1 (de)	2003-06-15
PL325425A1 (en)	1998-07-20
CN1202152A (zh)	1998-12-16
IL123293A (en)	2003-06-24
KR19990044459A (ko)	1999-06-25
ES2201192T3 (es)	2004-03-16
IL123293A0 (en)	1998-09-24
DK0863875T3 (da)	2003-12-01
RU2167865C2 (ru)	2001-05-27
MY121967A (en)	2006-03-31

Publication	Publication Date	Title
BR9610385A (pt)	1999-07-06	Novas 4-(oxalcoxifenil)-3-óxi-piperidinas para tratamento de insuficiência cardiáca e renal
DK0871606T3 (da)	2000-07-31	Nye forbindelser og deres præparat med anti-inflammatorisk og anti-thrombotisk aktivitet
NO980848D0 (no)	1998-02-27	Piperazinoderivater som neurokininantagonister
ATE264846T1 (de)	2004-05-15	Substituierte benzimidazol-derivaten und ihre verwendung zur behandlung retroviraler infektionen
SE9604786D0 (sv)	1996-12-20	New compounds
DE69817802D1 (de)	2003-10-09	Substituierte phenylderivate, ihre herstellung und verwendung
NZ325449A (en)	2000-01-28	Naphthyl-substituted benzimidazole derivatives as anticoagulants
DE59709414D1 (de)	2003-04-03	Oxyiminopregnancarbolactone
DE60322267D1 (de)	2008-08-28	Chinolinderivate als glucokinase liganden
DK1000033T3 (da)	2004-08-02	Heterocykliske derivater, som inhiberer Faktor Xa
EE200000527A (et)	2002-02-15	Faktorit Xa pärssivad heterotsüklilised derivaadid
BG102623A (bg)	1999-03-31	Нови производни на бензоилгуанидина, методи за тяхното получаване и приложението им за производството на ле- карствени средства
TR199700206A2 (xx)	1997-10-21	Floralkil- ve floralkoksi ikame edilmi� heterosiklik bradikinin-antagonistleri, bunlar�n imal edilmesine mahsus usul ve bunlar�n kullan�lmalar�.
NO975028L (no)	1997-12-30	Piperazinoderivater som neurokininantagonister
BG104232A (bg)	2000-10-31	Заместени 1,2,3,4,5,6-хексахидро-2,6-метано-3-бензазоцин- 10-оли, метод за тяхното получаване и приложението им като лекарствени средства
DK0728138T3 (da)	2002-05-13	Anthracyclinderivater
BR9805437A (pt)	2000-05-02	Derivados de benzocicloalquenos heterocìclicos, processo para fabricação de derivados de benzocicloalquenos heterocìclicos e uso de derivados de benzocicloalquenos heterocìclicos.
NO973241L (no)	1997-07-11	Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av hyperlipoproteinemi, hypertriglyceridemi, hyperlipidemi eller hyperkolesterolemi, eller arteriosklerose, eller for antikoagulativ b
TR199901570T2 (xx)	1999-09-21	N�rokinin antagonistleri olarak piperazin t�revleri
DE69808922D1 (de)	2002-11-28	Thiazolobenzoheterocyclen, ihre herstellung und diese enthaltende phatrmazeutische zubereitungen
DE59901563D1 (de)	2002-07-04	N-substituierte azabicycloheptan-derivate, ihre herstellung und verwendung
DK0784973T3 (da)	2002-03-18	Quinoxalinderivater til behandling af tinnitus
ATE183502T1 (de)	1999-09-15	Octahydro-2-naphthalincarbonsäure-derivate, ihre herstellung und verwendung

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