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BR9610347A - Bioconjugates of manganese complexes of nitrogen-containing macrocyclic binders effective as catalysts for superoxide dismutation - Google Patents

Bioconjugates of manganese complexes of nitrogen-containing macrocyclic binders effective as catalysts for superoxide dismutation

Info

Publication number
BR9610347A
BR9610347A BR9610347A BR9610347A BR9610347A BR 9610347 A BR9610347 A BR 9610347A BR 9610347 A BR9610347 A BR 9610347A BR 9610347 A BR9610347 A BR 9610347A BR 9610347 A BR9610347 A BR 9610347A
Authority
BR
Brazil
Prior art keywords
bioconjugates
catalysts
nitrogen
manganese complexes
containing macrocyclic
Prior art date
Application number
BR9610347A
Other languages
Portuguese (pt)
Inventor
William L Neumann
Dennis P Riley
Randy H Weiss
Susan L Henke
Patrick J Lennon
Karl W Aston
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of BR9610347A publication Critical patent/BR9610347A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
BR9610347A 1995-08-17 1996-08-14 Bioconjugates of manganese complexes of nitrogen-containing macrocyclic binders effective as catalysts for superoxide dismutation BR9610347A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US242195P 1995-08-17 1995-08-17
PCT/US1996/012767 WO1997006824A2 (en) 1995-08-17 1996-08-14 Bioconjugates of manganese complexes and their application as catalysts

Publications (1)

Publication Number Publication Date
BR9610347A true BR9610347A (en) 1999-06-01

Family

ID=21700675

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9610347A BR9610347A (en) 1995-08-17 1996-08-14 Bioconjugates of manganese complexes of nitrogen-containing macrocyclic binders effective as catalysts for superoxide dismutation

Country Status (12)

Country Link
EP (1) EP0844886A2 (en)
JP (1) JP2000513322A (en)
KR (1) KR19990037647A (en)
CN (1) CN1200039A (en)
AU (1) AU700958B2 (en)
BR (1) BR9610347A (en)
CA (1) CA2229799A1 (en)
CZ (1) CZ39898A3 (en)
IL (1) IL123040A0 (en)
NO (1) NO980649L (en)
PL (1) PL324993A1 (en)
WO (1) WO1997006824A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
EP1045851B1 (en) 1997-11-03 2003-04-23 Duke University Substituted porphyrins
EP1616869B1 (en) 1999-01-25 2012-04-04 National Jewish Health Substituted porphyrins and their therapeutic use
DE60032175T2 (en) * 1999-12-23 2007-09-27 Ge Healthcare Ltd., Little Chalfont MARKED ASCORBINIC ACID DERIVATIVES
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
WO2002098431A1 (en) 2001-06-01 2002-12-12 National Jewish Medical And Research Center Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
WO2003103680A1 (en) 2002-06-07 2003-12-18 Duke University Substituted porphyrins
EP2300032A4 (en) 2008-05-13 2012-12-05 Univ Kansas METAL ABSTRACTIONSPEPTID (MAP) DAY AND RELEVANT PROCEDURES
ES2600469T3 (en) 2008-05-23 2017-02-09 National Jewish Health A compound for use in the treatment of lesions associated with exposure to phosgene gas or chlorine gas
AU2012316397B2 (en) * 2011-09-26 2016-07-21 Galera Labs, Llc Methods for treatment of diseases
US9187735B2 (en) 2012-06-01 2015-11-17 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
WO2018152353A2 (en) * 2017-02-15 2018-08-23 Galera Labs, Llc Pentaaza macrocyclic ring complexes for local intestinal delivery
CN108752383B (en) * 2018-05-02 2020-10-30 江苏理工学院 A kind of pyrazole carboxylate manganese complex with SOD activity and preparation method thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880832A (en) * 1987-03-06 1989-11-14 Sumitomo Pharmaceuticals Company, Ltd. Liposoluble platinum (II) complex and preparation thereof
EP0524161A1 (en) * 1991-07-19 1993-01-20 Monsanto Company Manganese complexes of nitrogen containing macrocyclic ligands effective as catalysts for dismutating superoxide
US6204259B1 (en) * 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
BR9507477A (en) * 1994-04-22 1997-09-16 Searle & Co Diagnostic image analysis methods using metal complexes of macrocyclic ligands containing nitrogen
US6525041B1 (en) * 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
JPH11507621A (en) * 1995-06-07 1999-07-06 モンサント カンパニー Process for producing substituted polyaza macrocycles

Also Published As

Publication number Publication date
WO1997006824A2 (en) 1997-02-27
NO980649D0 (en) 1998-02-16
KR19990037647A (en) 1999-05-25
CN1200039A (en) 1998-11-25
PL324993A1 (en) 1998-07-06
AU6765596A (en) 1997-03-12
AU700958B2 (en) 1999-01-14
EP0844886A2 (en) 1998-06-03
IL123040A0 (en) 1998-09-24
CZ39898A3 (en) 1998-07-15
WO1997006824A3 (en) 1997-07-03
JP2000513322A (en) 2000-10-10
MX9801322A (en) 1998-05-31
NO980649L (en) 1998-04-02
CA2229799A1 (en) 1997-02-27

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B15K Others concerning applications: alteration of classification

Ipc: C07F 13/00 (2006.01), A61K 49/06 (2006.0