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BR9610106A - Uso de aminoácidos básicos e derivados para diminuir níveis de ceramida - Google Patents

Uso de aminoácidos básicos e derivados para diminuir níveis de ceramida

Info

Publication number
BR9610106A
BR9610106A BR9610106A BR9610106A BR9610106A BR 9610106 A BR9610106 A BR 9610106A BR 9610106 A BR9610106 A BR 9610106A BR 9610106 A BR9610106 A BR 9610106A BR 9610106 A BR9610106 A BR 9610106A
Authority
BR
Brazil
Prior art keywords
derivatives
decrease
amino acids
basic amino
ceramide levels
Prior art date
Application number
BR9610106A
Other languages
English (en)
Inventor
Sonia Moretti
Original Assignee
Simga Tau Ind Farmaceutiche Ri
Mendes Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Simga Tau Ind Farmaceutiche Ri, Mendes Srl filed Critical Simga Tau Ind Farmaceutiche Ri
Publication of BR9610106A publication Critical patent/BR9610106A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR9610106A 1995-08-03 1996-07-19 Uso de aminoácidos básicos e derivados para diminuir níveis de ceramida BR9610106A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95RM000545A IT1277898B1 (it) 1995-08-03 1995-08-03 Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
PCT/IT1996/000147 WO1997005862A2 (en) 1995-08-03 1996-07-19 Use of basic amino acids and derivatives for lowering ceramide levels

Publications (1)

Publication Number Publication Date
BR9610106A true BR9610106A (pt) 1999-02-23

Family

ID=11403513

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9610106A BR9610106A (pt) 1995-08-03 1996-07-19 Uso de aminoácidos básicos e derivados para diminuir níveis de ceramida

Country Status (18)

Country Link
US (2) US6114385A (pt)
EP (1) EP0844875B1 (pt)
JP (1) JPH11510182A (pt)
KR (1) KR100423760B1 (pt)
CN (1) CN1138539C (pt)
AR (1) AR003473A1 (pt)
AT (1) ATE349206T1 (pt)
AU (1) AU713207B2 (pt)
BR (1) BR9610106A (pt)
CA (1) CA2228281C (pt)
DE (1) DE69636792T2 (pt)
DK (1) DK0844875T3 (pt)
ES (1) ES2279523T3 (pt)
IT (1) IT1277898B1 (pt)
PT (1) PT844875E (pt)
RU (1) RU2179850C2 (pt)
TW (1) TW434011B (pt)
WO (1) WO1997005862A2 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277898B1 (it) 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1277897B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
IT1284661B1 (it) * 1996-06-06 1998-05-21 Sigma Tau Ind Farmaceuti Uso di alcanoil l-carnitine nel trattamento terapeutico di malattie infiammatorie croniche intestinali.
FR2778562B1 (fr) * 1998-05-14 2000-08-04 Sephra Composition pharmaceutique, hygienique et/ou cosmetique contenant de l'eau de mer et de l'arginine
PT1100589E (pt) * 1998-07-30 2005-05-31 Sigma Tau Ind Farmaceuti Utilizacao de propionil-l-carnitina e acetil-l-carnitina na preparacao de medicamentos com actividade anticancerigena
IT1302289B1 (it) * 1998-09-30 2000-09-05 Univ Catania Composizioni farmaceutiche ad attivita' antineoplastica
AU4013900A (en) * 1999-03-19 2000-10-09 Enos Pharmaceuticals, Inc. Increasing cerebral bioavailability of drugs
US20010025027A1 (en) * 2000-03-07 2001-09-27 Sonis Stephen T. Inhibition of ceramide for the prevention and treatment of oral mucositis induced by antineoplastic drugs or radiation
CN1489460A (zh) * 2001-01-30 2004-04-14 味之素株式会社 炎症性疾病治疗预防剂
US20080145424A1 (en) * 2002-10-24 2008-06-19 Enos Phramaceuticals, Inc. Sustained release L-arginine formulations and methods of manufacture and use
MXPA05004290A (es) * 2002-10-24 2005-11-23 Enos Pharmaceuticals Inc Formulaciones de l-arginina de liberacion sostenida, y metodos para su fabricacion y uso.
IL156670A0 (en) * 2003-06-26 2004-01-04 Zvi Zolotariov Aloe suppositories
AU2004279298B2 (en) * 2003-09-29 2009-01-29 Palmetto Pharmaceuticals, Llc Sustained release L-arginine formulations and methods of manufacture and use
JP2007055900A (ja) * 2003-12-15 2007-03-08 Ajinomoto Co Inc 炎症性疾患の治療及び予防用医薬組成物
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
RU2268718C1 (ru) * 2004-11-09 2006-01-27 Казанский государственный медицинский университет Способ предотвращения развития осложнений экспериментального инфаркта миокарда у крыс
EA019268B1 (ru) * 2010-12-01 2014-02-28 Общество С Ограниченной Ответственностью "Анвилаб" Комбинированное средство, обладающее гепатопротекторным действием
CN103142735B (zh) * 2013-03-09 2014-07-23 河北工程大学 一种治疗鸭病毒性肝炎的中药口服液
EP3764103A1 (en) * 2019-07-12 2021-01-13 Urgo Recherche Innovation Et Developpement Method of diagnosis or prognosis of a non-healing or chronic wound
US20230346735A1 (en) * 2020-04-28 2023-11-02 Lonza Greenwood Llc Nutritional Composition Comprising Carnitine and Method for Treating or Preventing an Infection in a Mammal
US20250360158A1 (en) * 2022-06-13 2025-11-27 Neubase Therapeutics, Inc. Oligonucleotide analogue formulations

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518617B2 (en) * 1977-04-29 1981-10-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Therapeutic application of acetyl-d, 1-carnitine
DE2946563C2 (de) * 1979-11-17 1987-04-30 B. Braun Melsungen Ag, 3508 Melsungen Aminosäurelösung zur parenteralen Infusion
JPH0247447B2 (ja) * 1982-05-27 1990-10-19 Teijin Ltd Kohotaikanohikuiigmsoseibutsu
JPS6130567A (ja) * 1984-07-23 1986-02-12 Shiseido Co Ltd 尿素の安定化法
JPH02124822A (ja) * 1988-11-02 1990-05-14 Eisai Co Ltd セファロスポリン含有注射用組成物
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
US6294520B1 (en) * 1989-03-27 2001-09-25 Albert T. Naito Material for passage through the blood-brain barrier
EP0400547A1 (en) * 1989-06-02 1990-12-05 Abbott Laboratories Parenteral nutrition product
IT1244636B (it) * 1991-01-04 1994-08-08 Sigma Tau Ind Farmaceuti Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
IT1248321B (it) * 1991-05-15 1995-01-05 Sigma Tau Ind Farmaceuti Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie
IT1245869B (it) * 1991-06-05 1994-10-25 Sigma Tau Ind Farmaceuti Impiego di propionil l-carnitina per il recupero del tono muscolare in soggetti immobilizzati
IT1254136B (it) * 1992-01-16 1995-09-08 Sigma Tau Ind Farmaceuti Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.
AU6922994A (en) * 1993-06-21 1995-01-17 Bernardini, Attilio Use of acylcarnitin to treat illnesses caused by aids
IT1277897B1 (it) 1995-08-03 1997-11-12 Mendes Srl Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
IT1277898B1 (it) 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1283951B1 (it) * 1996-03-15 1998-05-07 Mendes Srl Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di

Also Published As

Publication number Publication date
WO1997005862A2 (en) 1997-02-20
CN1193911A (zh) 1998-09-23
US6114385A (en) 2000-09-05
KR100423760B1 (ko) 2004-08-25
PT844875E (pt) 2007-02-28
MX9800916A (es) 1998-10-31
CA2228281A1 (en) 1997-02-20
EP0844875A2 (en) 1998-06-03
CN1138539C (zh) 2004-02-18
DE69636792D1 (de) 2007-02-08
AR003473A1 (es) 1998-08-05
RU2179850C2 (ru) 2002-02-27
AU713207B2 (en) 1999-11-25
ITRM950545A0 (it) 1995-08-03
JPH11510182A (ja) 1999-09-07
EP0844875B1 (en) 2006-12-27
ITRM950545A1 (it) 1997-02-03
HK1015274A1 (en) 1999-10-15
ES2279523T3 (es) 2007-08-16
CA2228281C (en) 2008-03-25
AU6469196A (en) 1997-03-05
KR19990036148A (ko) 1999-05-25
DK0844875T3 (da) 2007-04-10
ATE349206T1 (de) 2007-01-15
WO1997005862A3 (en) 1997-04-17
TW434011B (en) 2001-05-16
IT1277898B1 (it) 1997-11-12
US6350782B1 (en) 2002-02-26
DE69636792T2 (de) 2007-10-04

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]