[go: up one dir, main page]

BR9608758A - Uso de ribavirina e interferom alfa para o tratamento de hepatite c - Google Patents

Uso de ribavirina e interferom alfa para o tratamento de hepatite c

Info

Publication number
BR9608758A
BR9608758A BR9608758A BR9608758A BR9608758A BR 9608758 A BR9608758 A BR 9608758A BR 9608758 A BR9608758 A BR 9608758A BR 9608758 A BR9608758 A BR 9608758A BR 9608758 A BR9608758 A BR 9608758A
Authority
BR
Brazil
Prior art keywords
ribavirin
hepatitis
treatment
alpha interferon
interferon
Prior art date
Application number
BR9608758A
Other languages
English (en)
Inventor
Janice K Albrecht
Paul C Grint
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of BR9608758A publication Critical patent/BR9608758A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR9608758A 1995-05-19 1996-05-15 Uso de ribavirina e interferom alfa para o tratamento de hepatite c BR9608758A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/444,584 US6387365B1 (en) 1995-05-19 1995-05-19 Combination therapy for chronic hepatitis C infection
PCT/US1996/006552 WO1996036351A1 (en) 1995-05-19 1996-05-15 Use of ribavirin and interferon alpha for the treatment of hepatitis c

Publications (1)

Publication Number Publication Date
BR9608758A true BR9608758A (pt) 1999-07-06

Family

ID=23765515

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9608758A BR9608758A (pt) 1995-05-19 1996-05-15 Uso de ribavirina e interferom alfa para o tratamento de hepatite c

Country Status (15)

Country Link
US (2) US6387365B1 (pt)
EP (2) EP0707855A3 (pt)
JP (1) JPH10506640A (pt)
KR (1) KR19990014925A (pt)
CN (1) CN1190895A (pt)
AU (1) AU5919296A (pt)
BR (1) BR9608758A (pt)
CA (1) CA2221314A1 (pt)
CZ (1) CZ365497A3 (pt)
HU (1) HUP9802324A3 (pt)
NO (1) NO975309D0 (pt)
NZ (1) NZ309217A (pt)
PL (1) PL323477A1 (pt)
SK (1) SK155997A3 (pt)
WO (1) WO1996036351A1 (pt)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
DE69632062T2 (de) * 1995-11-02 2004-11-18 Schering Corp. Kontinuierliche, niedrigdosierte zytokine-infusionstherapie
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
JP3416147B2 (ja) * 1996-01-23 2003-06-16 アイ・シー・エヌ・フアーマシユーテイカルズ・インコーポレイテツド 活性化ｔリンパ球におけるリバビリン及びリバビリン類似体によるｔｈ１型／ｔｈ２型サイトカインの発現の調節
US20020137696A1 (en) * 1996-01-23 2002-09-26 Robert Tam Specific modulation of TH1/TH2 cytokine expression by ribavirin in activated T-lymphocytes
RU2186569C2 (ru) * 1996-01-23 2002-08-10 Ай-Си-Эн ФАРМАСЬЮТИКАЛЗ Модуляция экспрессии тн1/тн2 цитокинов рибавирином и аналогами рибавирина в активированных т-лимфоцитах
GEP20012489B (en) * 1996-02-28 2001-07-25 Ifi Inst Farmacoterapico Italiano S P A Use of Natural Human α-Interferon
AU5157998A (en) * 1996-11-01 1998-05-29 Thomas Najarian Methods and compositions for treatment of hepatitis c infection
US6172046B1 (en) 1997-09-21 2001-01-09 Schering Corporation Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection
US6472373B1 (en) 1997-09-21 2002-10-29 Schering Corporation Combination therapy for eradicating detectable HCV-RNA in antiviral treatment naive patients having chronic hepatitis C infection
DE69810822T2 (de) * 1997-09-21 2003-11-20 Schering Corp., Kenilworth Kombinationstherapie zur Entfernung von nachweisbarer HCV-RNS in Patienten mit chronischer Hepatitis C-Infection
NZ504994A (en) * 1997-12-22 2002-10-25 Schering Corp Orally administrable rapidly dissolving solid ribavirin dosage forms
CA2331823A1 (en) * 1998-05-15 1999-11-25 Schering Corporation Combination therapy comprising ribavirin and interferon alpha in antiviral treatment naive patients having g chronic hepatitis c infection
RS50144B (sr) * 1998-06-08 2009-03-25 F. Hoffmann-La Roche Ag., Primena peg-inf-alfa 2a i ribavirina za proizvodnju leka za lečenje hroničnog hepatitisa c
CN1324250A (zh) * 1998-09-04 2001-11-28 维洛药品公司 治疗或预防病毒感染及其所致疾病的方法
US6277830B1 (en) * 1998-10-16 2001-08-21 Schering Corporation 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
US6403564B1 (en) 1998-10-16 2002-06-11 Schering Corporation Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
NZ510811A (en) * 1998-10-16 2003-06-30 Schering Corp Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
AU2156900A (en) * 1998-12-18 2000-07-12 Schering Corporation Ribavirin-interferon alfa induction hcv combination therapy
AR021876A1 (es) * 1998-12-18 2002-08-07 Schering Corp Terapia de combinacion para vhc por induccion de ribavirina - interferon alfa pegilado
US6824768B2 (en) * 1998-12-18 2004-11-30 Schering Corporation Ribavirin-pegylated interferon alfa induction HCV combination therapy
PL364927A1 (en) * 1999-12-23 2004-12-27 Icn Pharmaceuticals, Inc. Compositions and methods for l-nucleosides, l-nucleotides, and their analogs
EP1803730A1 (en) 2000-04-12 2007-07-04 Human Genome Sciences, Inc. Albumin fusion proteins
AU2001255495A1 (en) * 2000-04-20 2001-11-07 Schering Corporation Ribavirin-interferon alfa combination therapy for eradicating detectable hcv-rnain patients having chronic hepatitis c infection
JP2004505114A (ja) * 2000-08-02 2004-02-19 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド エリスロポエチンの投与による改良された抗ウイルスおよび抗腫瘍化学療法
WO2002015664A2 (en) * 2000-08-23 2002-02-28 The New York Hospital Medical Center Of Queens Methods of preventing or treating west nile virus and other infections
US20060024270A1 (en) * 2000-08-23 2006-02-02 The New York Hospital Medical Center Of Queens Compositions and methods for preventing or treating encephalitis with interferon
AU2002213343A1 (en) * 2000-10-18 2002-04-29 Schering Corporation Ribavirin-pegylated interferon alfa HCV combination therapy
US6720000B2 (en) 2001-03-19 2004-04-13 Three Rivers Pharmaceutical, Llc Process for producing wet ribavirin pellets
WO2002097038A2 (en) * 2001-05-25 2002-12-05 Human Genome Sciences, Inc. Chemokine beta-1 fusion proteins
AU2002346686A1 (en) * 2001-12-07 2003-06-23 Intermune, Inc. Compositions and method for treating hepatitis virus infection
KR101271635B1 (ko) * 2001-12-21 2013-06-12 휴먼 게놈 사이언시즈, 인코포레이티드 알부민 융합 단백질
EP2277910A1 (en) 2001-12-21 2011-01-26 Human Genome Sciences, Inc. Albumin fusion proteins
EP1534299A4 (en) * 2002-07-02 2007-04-11 Corcept Therapeutics Inc METHOD FOR TREATING PSYCHOSIS IN CONNECTION WITH INTERFERON-ALPHA THERAPY
AU2003263552A1 (en) * 2002-09-09 2004-03-29 Nautilus Biotech Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
US7538094B2 (en) 2002-09-19 2009-05-26 Three Rivers Pharmacueticals, Llc Composition containing ribavirin and use thereof
JP2004143113A (ja) * 2002-10-25 2004-05-20 Shinya Nakajima インターフェロン製剤及びその投与システム
EP1594530A4 (en) 2003-01-22 2006-10-11 Human Genome Sciences Inc HYBRID PROTEINS OF ALBUMIN
GB0301879D0 (en) * 2003-01-27 2003-02-26 Regent Res Llp HCV combination therapy
WO2004084796A2 (en) * 2003-03-28 2004-10-07 Pharmasset Ltd. Compounds for the treatment of flaviviridae infections
CA2532664A1 (en) 2003-07-18 2005-01-27 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
WO2006033453A1 (ja) * 2004-09-22 2006-03-30 Juntendo Educational Foundation インターフェロン作用物質の活性増強剤
US7723310B2 (en) 2004-10-18 2010-05-25 Three Rivers Pharmaceuticals, Llc Large dose ribavirin formulations
US20060159658A1 (en) * 2005-01-19 2006-07-20 Avigenics, Inc. Methods of treating disease with glycosylated interferon
WO2007013677A1 (ja) * 2005-07-27 2007-02-01 Ajinomoto Co., Inc. インターフェロン作用物質の活性増強剤
WO2008088581A2 (en) 2006-08-02 2008-07-24 United Therapeutics Corporation Liposome treatment of viral infections
JP2010510171A (ja) * 2006-08-21 2010-04-02 ユナイテッド セラピューティクス コーポレーション ウイルス感染症の治療のための併用療法
US20080260820A1 (en) * 2007-04-19 2008-10-23 Gilles Borrelly Oral dosage formulations of protease-resistant polypeptides
KR20100056479A (ko) * 2007-07-25 2010-05-27 바이오렉스 쎄라퓨틱스, 인코포레이티드 제어 방출 인터페론 약물 제품 및 이를 사용한 ｈｃｖ 감염의 치료
EP2282723A2 (en) * 2008-03-26 2011-02-16 University of Oxford Endoplasmic reticulum targeting liposomes
AU2009293493B2 (en) * 2008-09-17 2014-09-18 Boehringer Ingelheim International Gmbh Combination of HCV NS3 protease inhibitor with interferon and ribavirin
CA2757026A1 (en) * 2009-03-27 2010-09-30 The Chancellor, Masters And Scholars Of The University Of Oxford Cholesterol level lowering liposomes
EP2459211A1 (en) 2009-07-31 2012-06-06 Medtronic, Inc. Continuous subcutaneous administration of interferon- to hepatitis c infected patients
CA2779244A1 (en) 2009-10-30 2011-05-05 Boehringer Ingelheim International Gmbh Dosage regimens for hcv combination therapy comprising bi201335, interferon alpha and ribavirin
AU2013201532B2 (en) 2011-10-21 2014-10-02 Abbvie Ireland Unlimited Company Methods for treating HCV
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
EA201490837A1 (ru) 2011-10-21 2014-11-28 Эббви Инк. Способы лечения hcv, включающие по меньшей мере два противовирусных агента прямого действия, рибавирин, но не интерферон
EP2809334A4 (en) * 2012-02-01 2015-06-24 Abbvie Inc ONCE DAILY TREATMENT OF HEPATITIS C WITH RIBAVIRIN AND TARIBAVIRIN
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE29835E (en) 1971-06-01 1978-11-14 Icn Pharmaceuticals 1,2,4-Triazole nucleosides
US4211771A (en) 1971-06-01 1980-07-08 Robins Ronald K Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
US4530901A (en) 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US5676942A (en) * 1992-02-10 1997-10-14 Interferon Sciences, Inc. Composition containing human alpha interferon species proteins and method for use thereof

Also Published As

Publication number Publication date
US6299872B1 (en) 2001-10-09
AU5919296A (en) 1996-11-29
US6387365B1 (en) 2002-05-14
NZ309217A (en) 2000-08-25
PL323477A1 (en) 1998-03-30
KR19990014925A (ko) 1999-02-25
JPH10506640A (ja) 1998-06-30
EP1005868A1 (en) 2000-06-07
CA2221314A1 (en) 1996-11-21
EP0707855A2 (en) 1996-04-24
CZ365497A3 (cs) 1998-07-15
MX9708885A (es) 1998-03-31
WO1996036351A1 (en) 1996-11-21
HUP9802324A2 (hu) 1999-05-28
HUP9802324A3 (en) 2001-04-28
EP0707855A3 (en) 1996-11-27
CN1190895A (zh) 1998-08-19
NO975309L (no) 1997-11-19
NO975309D0 (no) 1997-11-19
SK155997A3 (en) 1998-10-07

Similar Documents

Publication Publication Date Title
BR9608758A (pt) Uso de ribavirina e interferom alfa para o tratamento de hepatite c
NO20006178D0 (no) Anvendelse av PEG-IFN-<alfa> og ribavirin for behandling av kronisk hepatitt C
BR9306463A (pt) Alfa alumina
DE69603627D1 (de) Keramischer Verbundkörper
DE69411514D1 (de) Flugabwehrsystem und Flugabwehrkörper dafür
BR9406990A (pt) Corpo e artigo absorventes
BR9707501A (pt) Composto composição farmacêutica e uso do composto
DE69707347D1 (de) Keramischer Wabenkörper
BR9707808A (pt) Composto composição farmacêutica e uso do composto
ITMI932412A1 (it) Uso di alfa 1-bloccanti nel trattamento della eiaculazione precoce
PT983271E (pt) Hemissulfato carbociclico nucleosidico e a sua utilizacao no tratamento de infeccoes virais
ITMI940282A0 (it) Procedimento e dispositivo per la depurazione di sostanze sgrassanti
BR8903389A (pt) Conjunto moto-redutor e utilizacao do mesmo
KR960010685A (ko) 펩티드 및 그 용도
BR9405804A (pt) Corpo de colméia extrudado de cerâmica e/ou de material metálico com flexibilidade elevada
PT804199E (pt) Uso de penciclovir para o tratamento de nevralgias pos-herpeticas
ZA988519B (en) Use of IFN-alpha and amantadine for the treatment of chronic hepatitis C
BR9507375A (pt) Tratamento de superficies particuladas
DE69407832D1 (de) Keramischer Körper
KR950701009A (ko) 복합체 및 그 사용방법(composite body and its use)
IT232712Y1 (it) Corpo luminoso per la realizzazione di quadri, pannelli ed oggetti in genere, con effetti luminosi variabili
ITMI912161A1 (it) Riduzione degli inquinanti nell'effluente di combustione
RU97111990A (ru) Обезболивающее и противозудное средство
ES1020152Y (es) Estribo para colocacion de vigas de refuerzo de techos y aplicaciones similares.
IT1279584B1 (it) Fionda di tipo perfezionato

Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal