[go: up one dir, main page]

BR9505178A - Derivados de ciclolignan imunosupressivos - Google Patents

Derivados de ciclolignan imunosupressivos

Info

Publication number
BR9505178A
BR9505178A BR9505178A BR9505178A BR9505178A BR 9505178 A BR9505178 A BR 9505178A BR 9505178 A BR9505178 A BR 9505178A BR 9505178 A BR9505178 A BR 9505178A BR 9505178 A BR9505178 A BR 9505178A
Authority
BR
Brazil
Prior art keywords
immunosuppressive
cyclolignan
derivatives
cyclolignan derivatives
immunosuppressive cyclolignan
Prior art date
Application number
BR9505178A
Other languages
English (en)
Inventor
Marina Gordaliza
Maria Angeles Castro
Feliciano Arilfo San
Original Assignee
Univ Salamanca
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Salamanca filed Critical Univ Salamanca
Publication of BR9505178A publication Critical patent/BR9505178A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/60Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BR9505178A 1994-11-14 1995-11-14 Derivados de ciclolignan imunosupressivos BR9505178A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9422947A GB9422947D0 (en) 1994-11-14 1994-11-14 Immunosuppressive cyclolignan derivatives

Publications (1)

Publication Number Publication Date
BR9505178A true BR9505178A (pt) 1997-10-28

Family

ID=10764358

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9505178A BR9505178A (pt) 1994-11-14 1995-11-14 Derivados de ciclolignan imunosupressivos

Country Status (13)

Country Link
US (1) US5739114A (pt)
EP (1) EP0711765B9 (pt)
JP (1) JPH08225534A (pt)
AR (1) AR001767A1 (pt)
AU (1) AU3784695A (pt)
BR (1) BR9505178A (pt)
CA (1) CA2162760A1 (pt)
DE (1) DE69531586T2 (pt)
ES (1) ES2206481T3 (pt)
GB (1) GB9422947D0 (pt)
IL (1) IL115982A (pt)
NZ (1) NZ280455A (pt)
ZA (1) ZA959665B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2289549A3 (en) 1999-10-01 2011-06-15 Immunogen, Inc. Immunoconjugates for treating cancer
KR100433679B1 (ko) * 2000-11-20 2004-06-09 김송배 신규의 4'-데메틸-4'-o-치환-1-데옥시포도필로톡신유도체 및 그의 기하 이성체, 그의 제조방법 및 그를포함하는 항암제
SE0102168D0 (sv) 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds
WO2009100349A1 (en) * 2008-02-09 2009-08-13 The Trustees Of Columbia University In The City Of New York Analogues of (-)-picropodophyllin, synthesis and uses thereof
JP2011525486A (ja) * 2008-06-23 2011-09-22 アクセラー エービー 活動亢進性免疫系を治療するためのシクロリグナンの使用
CA2912254C (en) 2013-05-10 2021-06-08 M. Alphabet 2, L.L.C. Methods of treating skin conditions using cyclolignan compounds
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567253A (en) * 1984-02-03 1986-01-28 Tony Durst 2-Substituted derivatives of podophyllotoxin and etoposide
JPH0720966B2 (ja) * 1984-12-28 1995-03-08 コンプハルム・エイビ− 製薬学的に活性な化合物を含有する病気治療剤
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof

Also Published As

Publication number Publication date
EP0711765A1 (en) 1996-05-15
AU3784695A (en) 1996-05-23
GB9422947D0 (en) 1995-01-04
DE69531586D1 (de) 2003-10-02
CA2162760A1 (en) 1996-05-15
AR001767A1 (es) 1997-12-10
ES2206481T3 (es) 2004-05-16
JPH08225534A (ja) 1996-09-03
IL115982A (en) 1999-10-28
EP0711765B1 (en) 2003-08-27
US5739114A (en) 1998-04-14
DE69531586T2 (de) 2004-06-24
ZA959665B (en) 1996-05-29
IL115982A0 (en) 1996-01-31
NZ280455A (en) 1998-09-24
EP0711765B9 (en) 2004-03-03

Similar Documents

Publication Publication Date Title
PT934320E (pt) Derivados de naftiridina
BR9708386A (pt) Derivados de 6-fenilpiridil-2-amina
DK0901474T3 (da) Arylpyrimidinderivater
PT833828E (pt) Derivados de rapamicina
DE59508427D1 (de) 3-aryl-4-hydroxy-delta 3 -dihydrothiophenon-derivate
NO981946D0 (no) Imidazoquinazolin-derivater
BR9611834A (pt) Derivados de oximetóxi-3-aril-pirona
BR9605434A (pt) Derivados de purin-6-ona
EP0708091A3 (en) Indoloyl-guanidines derivatives
DE69732576D1 (de) Tetrahydrobenzindolon-derivate
BR9709065A (pt) Derivados de alquilaminobenzotiazole e-benzoxazol
DE69430587D1 (de) Pyrimidin-acyclonukleosid-derivate
BR9509793A (pt) Derivados de tiofeneno
PT856007E (pt) Derivados de ciclopeptidos
EE9900182A (et) 2-metoksüfenüülpiperasiini derivaadid
BR9610597A (pt) Derivados de diarilalcenilamina
PT906279E (pt) Derivados de pirrol
PT931087E (pt) Novos derivados de piranosido
BR9507892A (pt) Novos derivados de diamino-metilideno
FI964853L (fi) Deasetoksitaksolijohdannaiset
BR9505178A (pt) Derivados de ciclolignan imunosupressivos
BR9506618A (pt) Derivados de difeniloxazolinas
BR9603508A (pt) Derivados de alquenil-benzoilguanidina
PT843675E (pt) Derivados de aza-antraciclinona
DE69510792D1 (de) Naphtochinonderivate

Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]