BR9505178A - Derivados de ciclolignan imunosupressivos - Google Patents
Derivados de ciclolignan imunosupressivosInfo
- Publication number
- BR9505178A BR9505178A BR9505178A BR9505178A BR9505178A BR 9505178 A BR9505178 A BR 9505178A BR 9505178 A BR9505178 A BR 9505178A BR 9505178 A BR9505178 A BR 9505178A BR 9505178 A BR9505178 A BR 9505178A
- Authority
- BR
- Brazil
- Prior art keywords
- immunosuppressive
- cyclolignan
- derivatives
- cyclolignan derivatives
- immunosuppressive cyclolignan
- Prior art date
Links
- 230000001506 immunosuppresive effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9422947A GB9422947D0 (en) | 1994-11-14 | 1994-11-14 | Immunosuppressive cyclolignan derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9505178A true BR9505178A (pt) | 1997-10-28 |
Family
ID=10764358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9505178A BR9505178A (pt) | 1994-11-14 | 1995-11-14 | Derivados de ciclolignan imunosupressivos |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5739114A (pt) |
| EP (1) | EP0711765B9 (pt) |
| JP (1) | JPH08225534A (pt) |
| AR (1) | AR001767A1 (pt) |
| AU (1) | AU3784695A (pt) |
| BR (1) | BR9505178A (pt) |
| CA (1) | CA2162760A1 (pt) |
| DE (1) | DE69531586T2 (pt) |
| ES (1) | ES2206481T3 (pt) |
| GB (1) | GB9422947D0 (pt) |
| IL (1) | IL115982A (pt) |
| NZ (1) | NZ280455A (pt) |
| ZA (1) | ZA959665B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2289549A3 (en) | 1999-10-01 | 2011-06-15 | Immunogen, Inc. | Immunoconjugates for treating cancer |
| KR100433679B1 (ko) * | 2000-11-20 | 2004-06-09 | 김송배 | 신규의 4'-데메틸-4'-o-치환-1-데옥시포도필로톡신유도체 및 그의 기하 이성체, 그의 제조방법 및 그를포함하는 항암제 |
| SE0102168D0 (sv) | 2001-06-19 | 2001-06-19 | Karolinska Innovations Ab | New use and new compounds |
| WO2009100349A1 (en) * | 2008-02-09 | 2009-08-13 | The Trustees Of Columbia University In The City Of New York | Analogues of (-)-picropodophyllin, synthesis and uses thereof |
| JP2011525486A (ja) * | 2008-06-23 | 2011-09-22 | アクセラー エービー | 活動亢進性免疫系を治療するためのシクロリグナンの使用 |
| CA2912254C (en) | 2013-05-10 | 2021-06-08 | M. Alphabet 2, L.L.C. | Methods of treating skin conditions using cyclolignan compounds |
| JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4567253A (en) * | 1984-02-03 | 1986-01-28 | Tony Durst | 2-Substituted derivatives of podophyllotoxin and etoposide |
| JPH0720966B2 (ja) * | 1984-12-28 | 1995-03-08 | コンプハルム・エイビ− | 製薬学的に活性な化合物を含有する病気治療剤 |
| US4644072A (en) * | 1985-04-12 | 1987-02-17 | Bristol-Myers Company | Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof |
-
1994
- 1994-11-14 GB GB9422947A patent/GB9422947D0/en active Pending
-
1995
- 1995-11-13 ES ES95308102T patent/ES2206481T3/es not_active Expired - Lifetime
- 1995-11-13 DE DE69531586T patent/DE69531586T2/de not_active Expired - Fee Related
- 1995-11-13 EP EP95308102A patent/EP0711765B9/en not_active Expired - Lifetime
- 1995-11-13 NZ NZ280455A patent/NZ280455A/xx unknown
- 1995-11-13 US US08/558,127 patent/US5739114A/en not_active Expired - Fee Related
- 1995-11-14 ZA ZA959665A patent/ZA959665B/xx unknown
- 1995-11-14 JP JP7295695A patent/JPH08225534A/ja active Pending
- 1995-11-14 CA CA002162760A patent/CA2162760A1/en not_active Abandoned
- 1995-11-14 BR BR9505178A patent/BR9505178A/pt not_active Application Discontinuation
- 1995-11-14 AU AU37846/95A patent/AU3784695A/en not_active Abandoned
- 1995-11-14 IL IL11598295A patent/IL115982A/xx active IP Right Review Request
- 1995-11-14 AR AR33423295A patent/AR001767A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0711765A1 (en) | 1996-05-15 |
| AU3784695A (en) | 1996-05-23 |
| GB9422947D0 (en) | 1995-01-04 |
| DE69531586D1 (de) | 2003-10-02 |
| CA2162760A1 (en) | 1996-05-15 |
| AR001767A1 (es) | 1997-12-10 |
| ES2206481T3 (es) | 2004-05-16 |
| JPH08225534A (ja) | 1996-09-03 |
| IL115982A (en) | 1999-10-28 |
| EP0711765B1 (en) | 2003-08-27 |
| US5739114A (en) | 1998-04-14 |
| DE69531586T2 (de) | 2004-06-24 |
| ZA959665B (en) | 1996-05-29 |
| IL115982A0 (en) | 1996-01-31 |
| NZ280455A (en) | 1998-09-24 |
| EP0711765B9 (en) | 2004-03-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |