BR9502062A - Composto processo para a sua preparaçao e composiçao farmaceutica - Google Patents
Composto processo para a sua preparaçao e composiçao farmaceuticaInfo
- Publication number
- BR9502062A BR9502062A BR9502062A BR9502062A BR9502062A BR 9502062 A BR9502062 A BR 9502062A BR 9502062 A BR9502062 A BR 9502062A BR 9502062 A BR9502062 A BR 9502062A BR 9502062 A BR9502062 A BR 9502062A
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- pharmaceutical composition
- compound process
- compounds
- hydroxylases
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- JWUBBDSIWDLEOM-UHFFFAOYSA-N 25-Hydroxycholecalciferol Natural products C1CCC2(C)C(C(CCCC(C)(C)O)C)CCC2C1=CC=C1CC(O)CCC1=C JWUBBDSIWDLEOM-UHFFFAOYSA-N 0.000 abstract 1
- JWUBBDSIWDLEOM-DCHLRESJSA-N 25-Hydroxyvitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C/C=C1\C[C@@H](O)CCC1=C JWUBBDSIWDLEOM-DCHLRESJSA-N 0.000 abstract 1
- JWUBBDSIWDLEOM-NQZHSCJISA-N 25-hydroxy-3 epi cholecalciferol Chemical compound C1([C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=CC=C1C[C@H](O)CCC1=C JWUBBDSIWDLEOM-NQZHSCJISA-N 0.000 abstract 1
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
- 102000008109 Mixed Function Oxygenases Human genes 0.000 abstract 1
- 108010074633 Mixed Function Oxygenases Proteins 0.000 abstract 1
- 229940124639 Selective inhibitor Drugs 0.000 abstract 1
- 229930003316 Vitamin D Natural products 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 150000003851 azoles Chemical class 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 238000007142 ring opening reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 235000019166 vitamin D Nutrition 0.000 abstract 1
- 239000011710 vitamin D Substances 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
- 229940046008 vitamin d Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Lubricants (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9409882A GB9409882D0 (en) | 1994-05-18 | 1994-05-18 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9502062A true BR9502062A (pt) | 1996-04-30 |
Family
ID=10755289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9502062A BR9502062A (pt) | 1994-05-18 | 1995-05-17 | Composto processo para a sua preparaçao e composiçao farmaceutica |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5622982A (pt) |
| EP (1) | EP0683156B1 (pt) |
| JP (1) | JP2912566B2 (pt) |
| KR (1) | KR100371465B1 (pt) |
| CN (1) | CN1060163C (pt) |
| AT (1) | ATE164576T1 (pt) |
| AU (1) | AU696880B2 (pt) |
| BR (1) | BR9502062A (pt) |
| CA (1) | CA2149459C (pt) |
| CO (1) | CO4290423A1 (pt) |
| CZ (1) | CZ285385B6 (pt) |
| DE (1) | DE69501915T2 (pt) |
| DK (1) | DK0683156T3 (pt) |
| ES (1) | ES2114289T3 (pt) |
| FI (1) | FI112364B (pt) |
| GB (1) | GB9409882D0 (pt) |
| GR (1) | GR3026505T3 (pt) |
| HK (1) | HK1008743A1 (pt) |
| HU (1) | HUT72063A (pt) |
| IL (1) | IL113743A (pt) |
| MY (1) | MY135559A (pt) |
| NO (1) | NO304738B1 (pt) |
| NZ (1) | NZ272129A (pt) |
| PE (1) | PE14896A1 (pt) |
| PH (1) | PH31510A (pt) |
| RU (1) | RU2152933C2 (pt) |
| SI (1) | SI0683156T1 (pt) |
| SK (1) | SK280326B6 (pt) |
| TW (1) | TW351718B (pt) |
| ZA (1) | ZA954074B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2843921B2 (ja) * | 1993-07-15 | 1999-01-06 | ファイザー製薬株式会社 | Ｐ物質拮抗剤としてのベンジルオキシキヌクリジン |
| JP3738450B2 (ja) * | 1995-11-20 | 2006-01-25 | 喜代司 喜多 | ビタミンｄ類やビタミンｋ類を配合した外用剤 |
| EP0998925A4 (en) * | 1997-05-26 | 2003-02-26 | New Vision Co Ltd | TOPICAL ADMINISTRATION COMPOSITIONS CONTAINING VITAMINS D AND VITAMINS K |
| US6034251A (en) * | 1997-11-07 | 2000-03-07 | Schering Corporation | Phenyl-alkyl-imidazoles |
| TW575562B (en) * | 1998-02-19 | 2004-02-11 | Agrevo Uk Ltd | Fungicides |
| IL129596A (en) * | 1998-05-08 | 2003-10-31 | Dow Agrosciences Llc | Preparation of 2-substituted pyridines |
| GB0029524D0 (en) * | 2000-12-04 | 2001-01-17 | Univ Sheffield | Disease treatment |
| GB0128415D0 (en) * | 2001-11-27 | 2002-01-16 | Univ Sheffield | Medicaments |
| JP2004196795A (ja) * | 2002-12-16 | 2004-07-15 | Wyeth | 外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル |
| US7429604B2 (en) * | 2004-06-15 | 2008-09-30 | Bristol Myers Squibb Company | Six-membered heterocycles useful as serine protease inhibitors |
| WO2006036892A2 (en) * | 2004-09-24 | 2006-04-06 | Sapphire Therapeutics, Inc. | Use of inhibitors of 24-hydroxylase in the treatment of cancer |
| WO2006032299A1 (en) * | 2004-09-24 | 2006-03-30 | Susanna Miettinen | Use of inhibitors of 24-hydroxylase in the treatment of cancer |
| CN104530038A (zh) * | 2014-12-10 | 2015-04-22 | 沈阳药科大学 | 酰胺咪唑类衍生物及其用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2041771C3 (de) * | 1970-08-22 | 1979-07-26 | Bayer Ag, 5090 Leverkusen | derivate |
| US4191767A (en) * | 1977-01-07 | 1980-03-04 | Westwood Pharmaceuticals, Inc. | Method for treating fungal infection in mammals with imidazo [1,2-a]quinoxalines |
| IT1097314B (it) * | 1978-07-26 | 1985-08-31 | Recordati Chem Pharm | Derivati dell'imidazolo ad attivita' anticonvulsivante |
| CH655103A5 (de) * | 1983-03-11 | 1986-03-27 | Sandoz Ag | Azolderivate, verfahren zu ihrer herstellung und ihre verwendung. |
| CH677925A5 (pt) * | 1986-12-03 | 1991-07-15 | Sandoz Ag | |
| DE3644616A1 (de) * | 1986-12-29 | 1988-07-07 | Lentia Gmbh | Imidazolderivate, verfahren zur herstellung und deren verwendung |
| IT1237792B (it) * | 1989-12-21 | 1993-06-17 | Zambon Spa | Composti attivi come inibitori dell'enzima hmg-coa reduttasi |
-
1994
- 1994-05-18 GB GB9409882A patent/GB9409882D0/en active Pending
-
1995
- 1995-05-16 FI FI952383A patent/FI112364B/fi active
- 1995-05-16 AT AT95810325T patent/ATE164576T1/de not_active IP Right Cessation
- 1995-05-16 SK SK635-95A patent/SK280326B6/sk not_active IP Right Cessation
- 1995-05-16 EP EP95810325A patent/EP0683156B1/en not_active Expired - Lifetime
- 1995-05-16 NZ NZ272129A patent/NZ272129A/en not_active IP Right Cessation
- 1995-05-16 AU AU20089/95A patent/AU696880B2/en not_active Ceased
- 1995-05-16 SI SI9530063T patent/SI0683156T1/xx not_active IP Right Cessation
- 1995-05-16 US US08/442,053 patent/US5622982A/en not_active Expired - Lifetime
- 1995-05-16 PE PE1995268750A patent/PE14896A1/es not_active Application Discontinuation
- 1995-05-16 CA CA002149459A patent/CA2149459C/en not_active Expired - Fee Related
- 1995-05-16 RU RU95107652/04A patent/RU2152933C2/ru not_active IP Right Cessation
- 1995-05-16 DK DK95810325T patent/DK0683156T3/da active
- 1995-05-16 NO NO951944A patent/NO304738B1/no not_active IP Right Cessation
- 1995-05-16 IL IL11374395A patent/IL113743A/xx not_active IP Right Cessation
- 1995-05-16 ES ES95810325T patent/ES2114289T3/es not_active Expired - Lifetime
- 1995-05-16 MY MYPI95001281A patent/MY135559A/en unknown
- 1995-05-16 DE DE69501915T patent/DE69501915T2/de not_active Expired - Lifetime
- 1995-05-16 CZ CZ951265A patent/CZ285385B6/cs not_active IP Right Cessation
- 1995-05-17 BR BR9502062A patent/BR9502062A/pt not_active IP Right Cessation
- 1995-05-17 JP JP7118345A patent/JP2912566B2/ja not_active Expired - Fee Related
- 1995-05-17 KR KR1019950012172A patent/KR100371465B1/ko not_active Expired - Fee Related
- 1995-05-17 PH PH50532A patent/PH31510A/en unknown
- 1995-05-17 HU HU9501451A patent/HUT72063A/hu not_active Application Discontinuation
- 1995-05-17 CN CN95106034A patent/CN1060163C/zh not_active Expired - Fee Related
- 1995-05-17 CO CO95021039A patent/CO4290423A1/es unknown
- 1995-05-18 ZA ZA954074A patent/ZA954074B/xx unknown
- 1995-05-19 TW TW084105010A patent/TW351718B/zh not_active IP Right Cessation
-
1998
- 1998-04-03 GR GR980400688T patent/GR3026505T3/el unknown
- 1998-07-20 HK HK98109296A patent/HK1008743A1/en not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE159012T1 (de) | Arylsulfonamido-substituierte hydroxamsäure derivate | |
| NO955256D0 (no) | Fenylheterosykluser som syklooksygenase-2-inhibitorer | |
| RU2088589C1 (en) | Derivatives of 17 beta-substituted-4-aza-5-5 alpha-androstane-3-ones, methods of synthesis of compounds, pharmaceutical composition, compound 4 | |
| DE69908819D1 (de) | Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten | |
| SE9903760D0 (sv) | New compounds | |
| BRPI0307351B8 (pt) | composto, composição farmacêutica, uso de um composto, e, processo para preparar um composto | |
| AU7815791A (en) | Heterocyclene derivatives | |
| ATE255579T1 (de) | Pyrrolidin-derivate die eine phospholipase-a2- hemmende wirkung haben | |
| BR9502062A (pt) | Composto processo para a sua preparaçao e composiçao farmaceutica | |
| DE69008142D1 (de) | 4-Substituierten Imidazolen zur Senkung des intraokularen Druckes. | |
| FI935800A0 (fi) | Antidepressiva och mot Parkisons sjukdom verksamma foereningar | |
| BRPI0410623A (pt) | composto, processo para preparação de um composto, composição farmacêutica, e, utilização de um composto | |
| PT91203A (pt) | Processo para a preparacao de novos derivados de antibioticos bu-3608 e de composicoes farmaceuticas que os contem | |
| BR9502079A (pt) | Composto,formulação farmaceutica e processo para preparar um composto | |
| GEP20063759B (en) | Novel Benzothiazine and Benzothiadiazine Derivatives, Method for Preparing Same and Pharmaceutical Compositions Containing Same | |
| MX9205921A (es) | Derivados de bis(fenil)etano, proceso para su preparacion y composicion farmaceutica que los contiene | |
| ES8305350A1 (es) | "un procedimiento para preparar derivados de dialcohilpirazol". | |
| BR9504004A (pt) | Composto processo para sua preparação e composição farmacêutica | |
| GEP20063757B (en) | Novel Benzothiazine and Benzothiadiazine Derivatives, Method for Preparing Same and Pharmaceutical Compositions Containing Same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: NOVARTIS AG (NOVARTIS SA) (NOVARTIS INC.) (CH) |
|
| FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
| FF | Decision: intention to grant | ||
| FG9A | Patent or certificate of addition granted | ||
| B24H | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi) | ||
| B24F | Patent annual fee: publication cancelled |
Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2257 DE 08/04/2014 POR TER SIDO INDEVIDA. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE AS 17A, 18A, 19A E 20A ANUIDADES. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2606 DE 15-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |