BR9406823A - Aminas secundárias e agentes anti-diabéticos e antiobesidade - Google Patents
Aminas secundárias e agentes anti-diabéticos e antiobesidadeInfo
- Publication number
- BR9406823A BR9406823A BR9406823A BR9406823A BR9406823A BR 9406823 A BR9406823 A BR 9406823A BR 9406823 A BR9406823 A BR 9406823A BR 9406823 A BR9406823 A BR 9406823A BR 9406823 A BR9406823 A BR 9406823A
- Authority
- BR
- Brazil
- Prior art keywords
- pct
- diabetic
- date dec
- secondary amines
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7602693A | 1993-06-14 | 1993-06-14 | |
| PCT/IB1994/000117 WO1994029290A1 (en) | 1993-06-14 | 1994-05-20 | Secondary amines as antidiabetic and antiobesity agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9406823A true BR9406823A (pt) | 1996-03-26 |
Family
ID=22129472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9406823A BR9406823A (pt) | 1993-06-14 | 1994-05-20 | Aminas secundárias e agentes anti-diabéticos e antiobesidade |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5767133A (pt) |
| EP (1) | EP0703911B1 (pt) |
| JP (1) | JPH08506348A (pt) |
| KR (1) | KR960703120A (pt) |
| CN (1) | CN1129443A (pt) |
| AT (1) | ATE154935T1 (pt) |
| AU (1) | AU675536B2 (pt) |
| BR (1) | BR9406823A (pt) |
| CA (1) | CA2164009A1 (pt) |
| CZ (1) | CZ327795A3 (pt) |
| DE (1) | DE69404039T2 (pt) |
| DK (1) | DK0703911T3 (pt) |
| ES (1) | ES2104383T3 (pt) |
| FI (1) | FI942791A7 (pt) |
| GR (1) | GR3024134T3 (pt) |
| HU (1) | HUT70844A (pt) |
| IL (1) | IL109904A0 (pt) |
| NO (1) | NO955047D0 (pt) |
| NZ (1) | NZ265692A (pt) |
| PL (1) | PL312005A1 (pt) |
| WO (1) | WO1994029290A1 (pt) |
| ZA (1) | ZA944139B (pt) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| US5541197A (en) * | 1994-04-26 | 1996-07-30 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| CA2171702A1 (en) * | 1995-03-14 | 1996-09-15 | Takashi Sohda | Benzofuran compounds and their use |
| US5977124A (en) * | 1995-05-10 | 1999-11-02 | Pfizer Inc. | β-adrenergic agonists |
| EP0828712A1 (en) * | 1995-05-10 | 1998-03-18 | Pfizer Inc. | Beta-adrenergic agonists |
| US6075040A (en) * | 1996-09-05 | 2000-06-13 | Eli Lilly And Company | Selective β3 adrenergic agonists |
| ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
| GB2305665A (en) * | 1995-09-26 | 1997-04-16 | Merck & Co Inc | Selective ß3 agonists for the treatment of diabetes aand obesity |
| AU6628596A (en) * | 1995-10-31 | 1997-05-22 | Pfizer Inc. | Processes and intermediates for preparing 1-(2-{2-isoxazol-3-ylbenzofuran-5-yloxy}ethylamino)-3-phenox y-2(s)-ol |
| JP3124242B2 (ja) | 1996-01-10 | 2001-01-15 | 旭化成工業株式会社 | 新規な３環性化合物 |
| AU715233B2 (en) * | 1996-01-10 | 2000-01-20 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel tricyclic compounds and drug compositions containing the same |
| US6008361A (en) * | 1996-04-09 | 1999-12-28 | Pfizer Inc. | Substituted pyridines |
| US6031105A (en) * | 1996-04-09 | 2000-02-29 | Pfizer Inc | Substituted pyridines |
| EP0801060A1 (en) * | 1996-04-09 | 1997-10-15 | Pfizer Inc. | Heterocyclic Beta-3 Adrenergenic Agonists |
| US5859044A (en) * | 1996-07-31 | 1999-01-12 | Pfizer Inc. | β-adrenergic agonists |
| ATE215369T1 (de) * | 1996-09-05 | 2002-04-15 | Lilly Co Eli | Carbazolanaloge als selektive beta3-adrenergische agonisten |
| KR20000053314A (ko) | 1996-11-14 | 2000-08-25 | 디. 제이. 우드, 스피겔 알렌 제이 | 치환된 피리딘의 제조 방법 |
| ES2203762T3 (es) * | 1996-11-14 | 2004-04-16 | Pfizer Inc. | Piridinas intermedias utiles en la sintesis de agonistas del receptor adrenergico beta. |
| AU6852898A (en) | 1997-04-17 | 1998-11-11 | Takeda Chemical Industries Ltd. | Thermogenic composition and benzazepine thermogenics |
| AU735249B2 (en) | 1997-07-03 | 2001-07-05 | Asahi Kasei Kabushiki Kaisha | Novel tricyclic compounds having saturated rings and medicinal compositions containing the same |
| CO5011072A1 (es) * | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
| US6051586A (en) * | 1997-12-19 | 2000-04-18 | Bayer Corporation | Sulfonamide substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| AU749097B2 (en) * | 1997-12-19 | 2002-06-20 | Bayer Corporation | Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| US6469031B1 (en) | 1998-12-18 | 2002-10-22 | Bayer Corporation | Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| US6121271A (en) * | 1998-05-12 | 2000-09-19 | American Home Products Corporation | Naphtho[2,3-B]heteroar-4-yl derivatives |
| EP1077968A1 (en) * | 1998-05-12 | 2001-02-28 | American Home Products Corporation | Naphtho[2,3-b]heteroar-4-yl derivatives |
| WO2000044737A1 (en) * | 1999-01-27 | 2000-08-03 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-ht(2c)) agonists |
| US7045545B1 (en) | 1999-01-27 | 2006-05-16 | Eli Lilly And Company | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists |
| DE19932314A1 (de) * | 1999-07-10 | 2001-01-11 | Merck Patent Gmbh | Benzofuranderivate |
| KR20020069215A (ko) * | 1999-12-16 | 2002-08-29 | 아사히 가세이 가부시키가이샤 | 신규한 치환기를 갖는 3환성 화합물 |
| WO2001083451A1 (en) * | 2000-04-28 | 2001-11-08 | Asahi Kasei Kabushiki Kaisha | Novel bicyclic compounds |
| AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
| AR035858A1 (es) | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
| WO2002100850A1 (en) * | 2001-06-08 | 2002-12-19 | Kuraray Co., Ltd. | Processes for preparation of heterocyclic compounds |
| KR100816527B1 (ko) * | 2001-09-12 | 2008-04-10 | 한국화학연구원 | 페닐테트라졸 유도체로 치환된 β-아미노알코올 화합물 |
| AU2002336311B8 (en) | 2001-10-25 | 2009-04-23 | Asahi Kasei Pharma Corporation | Bicyclic compound |
| US6864268B2 (en) | 2002-02-27 | 2005-03-08 | Pfizer Inc. | β3 adrenergic receptor agonists |
| AU2003209527A1 (en) | 2002-02-27 | 2003-09-09 | Pfizer Products Inc. | Crystal forms of (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol |
| BR0307996A (pt) * | 2002-02-27 | 2004-12-07 | Pfizer Prod Inc | Processos e intermediários úteis na preparação de receptores de agonistas beta3-adrenérgicos |
| ES2302938T3 (es) * | 2002-10-11 | 2008-08-01 | Pfizer Inc. | Derivados de indol como agonistas beta-2. |
| US6844362B2 (en) | 2002-10-11 | 2005-01-18 | Pfizer Inc | Indole derivatives useful for the treatment of diseases |
| EP1407769A1 (en) * | 2002-10-11 | 2004-04-14 | Pfizer Limited | Indole derivatives as beta-2 agonists |
| JP2006514069A (ja) * | 2003-01-06 | 2006-04-27 | イーライ リリー アンド カンパニー | Ｐｐａｒ調節因子としての融合複素環式誘導体 |
| EP1460064A1 (en) * | 2003-03-14 | 2004-09-22 | Pfizer Limited | Indole-2-carboxamide derivatives useful as beta-2 agonists |
| MXPA05011841A (es) | 2003-05-09 | 2006-01-26 | Hoffmann La Roche | Metil-indoles y metil-pirrolopiridinas como agonistas adrenergicos de alfa-1. |
| JP2008100916A (ja) * | 2005-01-24 | 2008-05-01 | Dainippon Sumitomo Pharma Co Ltd | インドール類およびそれを含む医薬組成物 |
| US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
| US8399666B2 (en) | 2005-11-04 | 2013-03-19 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| MX2010012814A (es) | 2008-05-23 | 2010-12-20 | Amira Pharmaceuticals Inc | Inhibidor de proteina activadora de 5-lipoxigenasa. |
| US8546431B2 (en) | 2008-10-01 | 2013-10-01 | Panmira Pharmaceuticals, Llc | 5-lipoxygenase-activating protein (FLAP) inhibitors |
| US8008506B2 (en) | 2008-10-09 | 2011-08-30 | Asahi Kasei Pharma Corporation | Indazole compounds |
| JPWO2010041568A1 (ja) | 2008-10-09 | 2012-03-08 | 旭化成ファーマ株式会社 | インダゾール誘導体 |
| US20100222404A1 (en) * | 2008-11-04 | 2010-09-02 | Asahi Kasei Pharma Corporation | Indazole derivative dihydrochloride |
| US20100173829A1 (en) * | 2008-11-07 | 2010-07-08 | Aston University | Glycoproteins Having Lipid Mobilizing Properties and Therapeutic Uses Thereof |
| AU2011245499B2 (en) * | 2010-04-30 | 2014-09-25 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
| EP4161503A4 (en) | 2020-06-08 | 2024-07-03 | Tactogen Inc. | Advantageous benzofuran compositions for mental disorders or enhancement |
| AU2021305165A1 (en) | 2020-07-06 | 2023-02-02 | Tactogen Inc | Advantageous benzothiophene compositions for mental disorders or enhancement |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1268960A (en) * | 1969-09-18 | 1972-03-29 | Sandoz Ltd | Indole derivatives |
| US3699123A (en) * | 1970-03-24 | 1972-10-17 | Sandoz Ltd | 4-(3-amino-2-hydroxy-propoxy) indole derivatives |
| DE2965655D1 (en) * | 1978-06-28 | 1983-07-21 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
| EP0021636B1 (en) * | 1979-06-16 | 1982-12-01 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
| DE3062216D1 (en) * | 1979-09-06 | 1983-04-07 | Beecham Group Plc | Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them |
| EP0029320B1 (en) * | 1979-11-15 | 1985-07-10 | Beecham Group Plc | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions |
| CA1175851A (en) * | 1980-09-26 | 1984-10-09 | Beecham Group Limited | Secondary amines |
| GR75101B (pt) * | 1980-10-23 | 1984-07-13 | Pfizer | |
| GB2096988B (en) * | 1980-11-20 | 1984-08-01 | Beecham Group Ltd | Aromatic hydroxyamines |
| FR2523964B1 (fr) * | 1982-03-23 | 1985-09-27 | Sanofi Sa | Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation |
| JPS60202872A (ja) * | 1984-03-27 | 1985-10-14 | Kaken Pharmaceut Co Ltd | ベンゾフラン誘導体、その製法およびそれを有効成分とする降圧剤 |
| US4882433A (en) * | 1985-10-30 | 1989-11-21 | The Upjohn Company | 3'-pyridinylalkylinden- and 3'-pyridinylalkylindol-2-carboxylic acids and analogs |
| GB8528633D0 (en) * | 1985-11-21 | 1985-12-24 | Beecham Group Plc | Compounds |
| US4886814A (en) * | 1986-03-13 | 1989-12-12 | Dr. Karl Thomas Gmbh | Substituted thiazoles and oxazoles and 2-hydroxy-morpholines |
| GB8714901D0 (en) * | 1986-07-23 | 1987-07-29 | Ici Plc | Amide derivatives |
| GB8925032D0 (en) * | 1989-11-06 | 1989-12-28 | Ici Plc | Chemical compounds |
| US5061727A (en) * | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
| US5106867A (en) * | 1990-05-04 | 1992-04-21 | American Cyanamid Company | Method of increasing lean meat in edible animals |
| JPH08165276A (ja) * | 1994-12-14 | 1996-06-25 | Dainippon Pharmaceut Co Ltd | ２−アルキルアミノ−１−フェニルエタノール誘導体 |
-
1994
- 1994-05-20 WO PCT/IB1994/000117 patent/WO1994029290A1/en not_active Ceased
- 1994-05-20 CA CA002164009A patent/CA2164009A1/en not_active Abandoned
- 1994-05-20 AU AU66870/94A patent/AU675536B2/en not_active Ceased
- 1994-05-20 BR BR9406823A patent/BR9406823A/pt not_active Application Discontinuation
- 1994-05-20 NZ NZ265692A patent/NZ265692A/en unknown
- 1994-05-20 PL PL94312005A patent/PL312005A1/xx unknown
- 1994-05-20 CN CN94193087A patent/CN1129443A/zh active Pending
- 1994-05-20 CZ CZ953277A patent/CZ327795A3/cs unknown
- 1994-05-20 DE DE69404039T patent/DE69404039T2/de not_active Expired - Fee Related
- 1994-05-20 DK DK94914531.2T patent/DK0703911T3/da active
- 1994-05-20 US US08/569,152 patent/US5767133A/en not_active Expired - Fee Related
- 1994-05-20 ES ES94914531T patent/ES2104383T3/es not_active Expired - Lifetime
- 1994-05-20 EP EP94914531A patent/EP0703911B1/en not_active Expired - Lifetime
- 1994-05-20 AT AT94914531T patent/ATE154935T1/de not_active IP Right Cessation
- 1994-05-20 KR KR1019950705694A patent/KR960703120A/ko not_active Ceased
- 1994-05-20 JP JP6520401A patent/JPH08506348A/ja active Pending
- 1994-06-06 IL IL10990494A patent/IL109904A0/xx unknown
- 1994-06-13 ZA ZA944139A patent/ZA944139B/xx unknown
- 1994-06-13 FI FI942791A patent/FI942791A7/fi not_active Application Discontinuation
- 1994-06-13 HU HU9401761A patent/HUT70844A/hu unknown
-
1995
- 1995-12-13 NO NO955047A patent/NO955047D0/no unknown
-
1997
- 1997-07-16 GR GR970401784T patent/GR3024134T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69404039T2 (de) | 1997-10-16 |
| HUT70844A (en) | 1995-11-28 |
| ES2104383T3 (es) | 1997-10-01 |
| FI942791L (fi) | 1994-12-15 |
| JPH08506348A (ja) | 1996-07-09 |
| PL312005A1 (en) | 1996-04-01 |
| DE69404039D1 (de) | 1997-08-07 |
| EP0703911A1 (en) | 1996-04-03 |
| EP0703911B1 (en) | 1997-07-02 |
| AU675536B2 (en) | 1997-02-06 |
| FI942791A7 (fi) | 1994-12-15 |
| WO1994029290A1 (en) | 1994-12-22 |
| KR960703120A (ko) | 1996-06-19 |
| ZA944139B (en) | 1995-12-13 |
| ATE154935T1 (de) | 1997-07-15 |
| CZ327795A3 (en) | 1996-08-14 |
| CN1129443A (zh) | 1996-08-21 |
| IL109904A0 (en) | 1994-10-07 |
| NZ265692A (en) | 1997-02-24 |
| NO955047L (no) | 1995-12-13 |
| US5767133A (en) | 1998-06-16 |
| GR3024134T3 (en) | 1997-10-31 |
| AU6687094A (en) | 1995-01-03 |
| NO955047D0 (no) | 1995-12-13 |
| FI942791A0 (fi) | 1994-06-13 |
| DK0703911T3 (da) | 1997-10-06 |
| HU9401761D0 (en) | 1994-09-28 |
| CA2164009A1 (en) | 1994-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: C07D 401/06 (2006.01), C07D 209/42 (2006.0 |