BR9404743A - Diamine salts of clavulanic acid - Google Patents
Diamine salts of clavulanic acidInfo
- Publication number
- BR9404743A BR9404743A BR9404743-0A BR9404743A BR9404743A BR 9404743 A BR9404743 A BR 9404743A BR 9404743 A BR9404743 A BR 9404743A BR 9404743 A BR9404743 A BR 9404743A
- Authority
- BR
- Brazil
- Prior art keywords
- clavulanic acid
- diamine salts
- salts
- diamine
- acid
- Prior art date
Links
- -1 Diamine salts Chemical class 0.000 title abstract 4
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 3
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical class OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 3
- 229960003324 clavulanic acid Drugs 0.000 title abstract 3
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D503/10—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D503/12—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 unsubstituted in position 6
- C07D503/14—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 unsubstituted in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, other than a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, attached in position 3
- C07D503/16—Radicals substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical
- C07D503/18—Radicals substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"SAIS DE DIAMINA DO áCIDO CLAVUL‰NICO". São proporcionados novos sais de diamina do ácido clavulânico, composições farmacêuticas contendo os mesmos e um novo processo que utiliza tais sais de diamina para a preparação do ácido clavulânico e sais e ésteres do mesmo."CLAVULINIC ACID DIAMINE SALTS". New diamine salts of clavulanic acid are provided, pharmaceutical compositions containing them and a new process that uses such diamine salts for the preparation of clavulanic acid and salts and esters thereof.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93200872 | 1993-03-26 | ||
| PCT/EP1994/000919 WO1994022873A1 (en) | 1993-03-26 | 1994-03-22 | Diamine salts of clavulanic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9404743A true BR9404743A (en) | 1999-09-28 |
Family
ID=8213723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9404743-0A BR9404743A (en) | 1993-03-26 | 1994-03-22 | Diamine salts of clavulanic acid |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JP2839955B2 (en) |
| KR (1) | KR100187333B1 (en) |
| BG (1) | BG61948B1 (en) |
| BR (1) | BR9404743A (en) |
| GR (2) | GR950300030T1 (en) |
| LV (1) | LV11180B (en) |
| RU (1) | RU2135502C1 (en) |
| SI (1) | SI0647229T1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1578739A (en) * | 1976-07-23 | 1980-11-05 | Beecham Group Ltd | Amine salts of clavulanic acid methods for their preparation and compositions containing them |
| AT399155B (en) * | 1992-03-26 | 1995-03-27 | Lek Tovarna Farmacevtskih | NEW ALKYLENE DIAMMONIUM DICLAVULANATE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF |
| SI9300296B (en) | 1992-06-11 | 1998-06-30 | Smithkline Beecham P.L.C. | The process and intermediates for the preparation of clavulanic acid |
| GB9305565D0 (en) | 1993-03-18 | 1993-05-05 | Smithkline Beecham Plc | Novel compounds and processes |
-
1994
- 1994-03-22 SI SI9430013T patent/SI0647229T1/en unknown
- 1994-03-22 JP JP6521641A patent/JP2839955B2/en not_active Expired - Lifetime
- 1994-03-22 RU RU94046014A patent/RU2135502C1/en active
- 1994-03-22 KR KR1019940704230A patent/KR100187333B1/en not_active Expired - Fee Related
- 1994-03-22 BR BR9404743-0A patent/BR9404743A/en not_active Application Discontinuation
- 1994-11-22 LV LVP-94-220A patent/LV11180B/en unknown
- 1994-11-25 BG BG99212A patent/BG61948B1/en unknown
-
1995
- 1995-06-30 GR GR950300030T patent/GR950300030T1/en unknown
-
1996
- 1996-10-16 GR GR960402720T patent/GR3021347T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LV11180B (en) | 1996-08-20 |
| RU2135502C1 (en) | 1999-08-27 |
| GR950300030T1 (en) | 1995-06-30 |
| KR950701635A (en) | 1995-04-28 |
| BG61948B1 (en) | 1998-10-30 |
| RU94046014A (en) | 1996-10-10 |
| BG99212A (en) | 1995-12-29 |
| SI0647229T1 (en) | 1997-10-31 |
| JP2839955B2 (en) | 1998-12-24 |
| GR3021347T3 (en) | 1997-01-31 |
| JPH07507573A (en) | 1995-08-24 |
| KR100187333B1 (en) | 1999-05-01 |
| LV11180A (en) | 1996-04-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer |
Free format text: DSM N.V. (NL) |
|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal |