BR9307689A - Oral compositions containing anti-plaque, anti-calculus agents - Google Patents
Oral compositions containing anti-plaque, anti-calculus agentsInfo
- Publication number
- BR9307689A BR9307689A BR9307689-4A BR9307689A BR9307689A BR 9307689 A BR9307689 A BR 9307689A BR 9307689 A BR9307689 A BR 9307689A BR 9307689 A BR9307689 A BR 9307689A
- Authority
- BR
- Brazil
- Prior art keywords
- oral
- agents
- compositions
- zinc
- ions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000002272 anti-calculus Effects 0.000 title abstract 2
- 230000002882 anti-plaque Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 2
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 abstract 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 abstract 2
- -1 citrate ions Chemical class 0.000 abstract 2
- 210000000214 mouth Anatomy 0.000 abstract 2
- 229910052698 phosphorus Inorganic materials 0.000 abstract 2
- 239000011574 phosphorus Substances 0.000 abstract 2
- ONDPHDOFVYQSGI-UHFFFAOYSA-N zinc nitrate Chemical compound [Zn+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ONDPHDOFVYQSGI-UHFFFAOYSA-N 0.000 abstract 2
- 206010006326 Breath odour Diseases 0.000 abstract 1
- 208000002064 Dental Plaque Diseases 0.000 abstract 1
- 229920000388 Polyphosphate Polymers 0.000 abstract 1
- 208000007565 gingivitis Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 abstract 1
- 239000001205 polyphosphate Substances 0.000 abstract 1
- 235000011176 polyphosphates Nutrition 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 239000011787 zinc oxide Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>"COMPOSIçõES ORAIS CONTENDO AGENTES ANTI-PLACA, ANTI-CáLCULO"<D>. Esta invenção envolve composições para o cuidado oral, compreendendo: (a) óxido de zinco ou nitrato de zinco; uma fonte de íons de citrato; e um ou mais agentes anti-cálculo contendo fósforo selecionados do grupo que consiste de pirofosfato, fosfonato, difostonato e polifosfatos condensados lineares farmaceuticamente aceitáveis da fórmula geral (P~ n~O~ (3n+1)~) ^ (n+2)- ^ onde n é um inteiro de 2 a 21; onde a razão molar dos íons de zinco:íons de citrato varia de cerca de 1:0,1 a cerca de 1:20; a razão molar dos íons de zinco:agentes anticálculo contendo fósforo varia de cerca de 1:1 a cerca de 1:20; e (b) um veículo oral tópico farmaceuticamente aceitável. Esta invenção também envolve métodos para o tratamento ou prevenção de placa dentária, cálculo, gengivite ou ma-hálito da cavidade oral, compreendendo a administração à cavidade oral de um homem ou outro animal de uma quantidade segura e eficaz destas composições.Invention Patent: <B> "ORAL COMPOSITIONS CONTAINING ANTI-PLATE, ANTI-CALCULATION AGENTS" <D>. This invention involves compositions for oral care, comprising: (a) zinc oxide or zinc nitrate; a source of citrate ions; and one or more phosphorus-containing anti-calculus agents selected from the group consisting of pharmaceutically acceptable linear condensed polyphosphates, phosphonate, dipostonate and the general formula (P ~ n ~ O ~ (3n + 1) ~) ^ (n + 2) - ^ where n is an integer from 2 to 21; where the molar ratio of zinc ions: citrate ions ranges from about 1: 0.1 to about 1:20; the molar ratio of zinc ions: phosphorus-containing anticalculating agents ranges from about 1: 1 to about 1:20; and (b) a pharmaceutically acceptable topical oral vehicle. This invention also involves methods for the treatment or prevention of dental plaque, calculus, gingivitis or bad breath from the oral cavity, comprising administering to the oral cavity of a man or other animal a safe and effective amount of these compositions.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99333692A | 1992-12-18 | 1992-12-18 | |
| US14877593A | 1993-11-16 | 1993-11-16 | |
| PCT/US1993/011786 WO1994014406A1 (en) | 1992-12-18 | 1993-12-06 | Oral compositions containing antiplaque, anticalculus agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9307689A true BR9307689A (en) | 1999-08-31 |
Family
ID=26846148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9307689-4A BR9307689A (en) | 1992-12-18 | 1993-12-06 | Oral compositions containing anti-plaque, anti-calculus agents |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0675705A1 (en) |
| JP (1) | JPH08504816A (en) |
| CN (1) | CN1095262A (en) |
| AU (1) | AU5739994A (en) |
| BR (1) | BR9307689A (en) |
| CA (1) | CA2151815A1 (en) |
| CZ (1) | CZ156895A3 (en) |
| HU (1) | HUT72042A (en) |
| MX (1) | MX9400052A (en) |
| TR (1) | TR27536A (en) |
| WO (1) | WO1994014406A1 (en) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5302373A (en) * | 1993-06-10 | 1994-04-12 | Church & Dwight Co., Inc. | Liquid mouthwash containing a particulate bicarbonate suspension |
| US5885556A (en) * | 1996-01-11 | 1999-03-23 | The Procter & Gamble Company | Tartar control oral compositions |
| US6190644B1 (en) * | 1996-11-21 | 2001-02-20 | The Procter & Gamble Company | Dentifrice compositions containing polyphosphate and monofluorophosphate |
| US6713049B1 (en) | 1999-11-12 | 2004-03-30 | The Procter & Gamble Company | Oral compositions providing optimal surface conditioning |
| US6350436B1 (en) | 1996-11-21 | 2002-02-26 | The Procter & Gamble Company | Method of reducing staining of stannous in dentifrice compositions |
| US5939052A (en) * | 1996-11-21 | 1999-08-17 | The Procter & Gamble Company | Dentifrice compositions containing polyphosphate and fluoride |
| US6350438B1 (en) * | 1998-02-27 | 2002-02-26 | The Procter & Gamble Company | Oral care compositions comprising chlorite and methods |
| US6846478B1 (en) * | 1998-02-27 | 2005-01-25 | The Procter & Gamble Company | Promoting whole body health |
| JPH11246376A (en) * | 1998-02-27 | 1999-09-14 | Sunstar Inc | Composition for oral cavity |
| GB9810806D0 (en) * | 1998-05-21 | 1998-07-22 | Boots Co Plc | Odour absorbing agent |
| US6447789B1 (en) * | 1999-10-13 | 2002-09-10 | Terrie E. Banks | Facial cleanser and method of treating skin conditions |
| ES2350177T3 (en) | 1999-11-12 | 2011-01-19 | THE PROCTER & GAMBLE COMPANY | ORAL COMPOSITIONS CONTAINING STANNY IONS. |
| MXPA02004783A (en) | 1999-11-12 | 2002-08-30 | Procter & Gamble | Improved dual phase stannous oral compositions. |
| US20040146466A1 (en) | 1999-11-12 | 2004-07-29 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| US10470985B2 (en) | 1999-11-12 | 2019-11-12 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| CA2431002A1 (en) * | 2000-12-05 | 2002-06-13 | Colgate-Palmolive Company | Zinc containing dentifrice of reduced astringency |
| ES2606367T3 (en) * | 2002-01-03 | 2017-03-23 | The Procter & Gamble Company | Stable oral compositions comprising casein and fluoride phosphopeptide complexes |
| JP2005139201A (en) * | 2002-11-19 | 2005-06-02 | Showa Yakuhin Kako Kk | Agent for dissolving dental calculi and dental caries |
| EP1586312A4 (en) | 2002-11-19 | 2007-02-14 | Showa Pharm Chem Ind | AGENT INTENDED TO DISSOLVE THE TARTAR AND THE DENTAL CARIES |
| JP3957293B2 (en) * | 2003-01-27 | 2007-08-15 | 花王株式会社 | Oral composition |
| DE10311171A1 (en) * | 2003-03-12 | 2004-09-23 | Henkel Kgaa | Oral and dental care composition with antitartar, antiplaque and anti-discoloration action, containing cationic antibacterial agent, aza-cycloalkane-diphosphonic acid and xanthan gum or carboxymethyl cellulose |
| MY151134A (en) * | 2005-12-21 | 2014-04-30 | Colgate Palmolive Co | Improved oral compositions comprising zinc citrate and / or tocopherol agents |
| ATE431128T1 (en) | 2006-03-22 | 2009-05-15 | Procter & Gamble | ORAL COMPOSITIONS CONTAINING ZINC |
| US8298516B2 (en) * | 2006-12-22 | 2012-10-30 | Douglas Anderson | Calculus dissolving dental composition and methods for using same |
| GB0706787D0 (en) * | 2007-04-05 | 2007-05-16 | Glaxo Group Ltd | Novel use |
| MX2010005130A (en) | 2007-11-09 | 2010-08-04 | Procter & Gamble | Oral stannous compositions. |
| CN101292943B (en) * | 2008-06-20 | 2010-04-14 | 陕西太和科技股份有限公司 | Nanometer zinc oxide toothpaste |
| IN2012DN02657A (en) | 2009-10-29 | 2015-09-11 | Colgate Palmolive Co | |
| TWI455728B (en) * | 2010-01-14 | 2014-10-11 | Colgate Palmolive Co | Dentifrice compositions |
| SG183905A1 (en) | 2010-03-31 | 2012-10-30 | Colgate Palmolive Co | Oral care composition |
| PL2519215T3 (en) | 2010-03-31 | 2017-02-28 | Colgate-Palmolive Company | Oral care composition |
| US10123953B2 (en) | 2012-06-21 | 2018-11-13 | The Procter & Gamble Company | Reduction of tooth staining derived from cationic antimicrobials |
| RU2679416C2 (en) | 2014-06-20 | 2019-02-08 | Колгейт-Палмолив Компани | Oral care compositions containing zinc, tin (ii) and fluoride ion sources |
| BR112017007639A2 (en) * | 2014-10-24 | 2018-06-19 | Colgate Palmolive Co | preparation of zinc citrate and oral hygiene compositions containing zinc citrate |
| BR112017011994B1 (en) * | 2014-12-16 | 2021-01-05 | Colgate-Palmolive Company | oral hygiene composition and use |
| AU2014415217B2 (en) * | 2014-12-26 | 2018-11-29 | Colgate-Palmolive Company | Zinc phosphate complex |
| RU2692066C2 (en) * | 2014-12-26 | 2019-06-20 | Колгейт-Палмолив Компани | Zinc phosphate complex |
| EP3223914B1 (en) * | 2014-12-26 | 2020-05-06 | Colgate-Palmolive Company | Zinc phosphate complex |
| RU2690157C2 (en) * | 2014-12-26 | 2019-05-31 | Колгейт-Палмолив Компани | Zinc phosphate complex for oral care |
| WO2016105433A1 (en) * | 2014-12-26 | 2016-06-30 | Colgate-Palmolive Company | Personal care compositions with zinc phosphate active |
| MX2017007692A (en) * | 2014-12-26 | 2017-10-27 | Colgate Palmolive Co | Personal care composition with zinc phosphate active. |
| US10813849B2 (en) * | 2015-02-05 | 2020-10-27 | University Of Maryland, Baltimore | Rechargeable calcium phosphate-containing dental materials |
| CN113747948B (en) | 2019-04-26 | 2023-12-15 | 宝洁公司 | Reduce tooth discoloration from cationic antimicrobials |
| JP2022099625A (en) * | 2020-12-23 | 2022-07-05 | 小林製薬株式会社 | Composition for oral cavity |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4187288A (en) * | 1975-01-28 | 1980-02-05 | Colgate Palmolive Company | Modified abrasive system for dentifrices |
| US4309409A (en) * | 1975-12-22 | 1982-01-05 | Stauffer Chemical Company | Anti-corrosion formulation for toothpastes |
| DE2747852A1 (en) * | 1977-10-26 | 1979-05-03 | Colgate Palmolive Co | Dentifrice with improved cleansing and polishing action - contg. abrasive agent together with zinc cpd. to reduce abrasion of dental enamel |
| AU1746088A (en) * | 1987-06-12 | 1988-12-15 | Unilever Plc | Oral compositions |
| NZ232572A (en) * | 1989-03-13 | 1991-11-26 | Vipont Pharma | Oral rinse composition containing a benzophenanthridine alkaloid extract from sanguinaria canadesis |
| US5000944A (en) * | 1989-06-09 | 1991-03-19 | Colgate-Palmolive Company | Zinc-containing oral products with reduced astringency |
-
1993
- 1993-12-06 JP JP6515184A patent/JPH08504816A/en active Pending
- 1993-12-06 EP EP94903458A patent/EP0675705A1/en not_active Ceased
- 1993-12-06 CA CA002151815A patent/CA2151815A1/en not_active Abandoned
- 1993-12-06 AU AU57399/94A patent/AU5739994A/en not_active Abandoned
- 1993-12-06 HU HU9501778A patent/HUT72042A/en unknown
- 1993-12-06 CZ CZ951568A patent/CZ156895A3/en unknown
- 1993-12-06 BR BR9307689-4A patent/BR9307689A/en not_active Application Discontinuation
- 1993-12-06 WO PCT/US1993/011786 patent/WO1994014406A1/en not_active Ceased
- 1993-12-10 TR TR01158/93A patent/TR27536A/en unknown
- 1993-12-18 CN CN93119916A patent/CN1095262A/en active Pending
-
1994
- 1994-01-03 MX MX9400052A patent/MX9400052A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9400052A (en) | 1994-07-29 |
| HUT72042A (en) | 1996-03-28 |
| TR27536A (en) | 1995-06-07 |
| CZ156895A3 (en) | 1996-01-17 |
| HU9501778D0 (en) | 1995-08-28 |
| JPH08504816A (en) | 1996-05-28 |
| CN1095262A (en) | 1994-11-23 |
| WO1994014406A1 (en) | 1994-07-07 |
| AU5739994A (en) | 1994-07-19 |
| EP0675705A1 (en) | 1995-10-11 |
| CA2151815A1 (en) | 1994-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: PROCEDIMENTO AUTOMATICO DE RECLASSIFICACAO. AS CLASSIFICACOES IPC ANTERIORES ERAM: A61K 7/16; A61K 33/42; A61K 33/30. Ipc: A61Q 11/00 (2006.01), A61K 8/24 (2006.01), A61K 8/ Ipc: A61Q 11/00 (2006.01), A61K 8/24 (2006.01), A61K 8/ |