BR9207024A - Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone - Google Patents

Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone

Info

Publication number: BR9207024A
Authority: BR; Brazil
Prior art keywords: hydrogeldanamycin; hydroquinone
Prior art date: 1992-01-06

Application number

BR9207024A

Other languages

Portuguese (pt)

Inventor

Walter P Cullen

Mark T Jefferson

Mikel P Moyer

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-06

Filing date

1992-12-03

Publication date

1995-12-05

1992-12-03 Application filed by Pfizer filed Critical Pfizer

1995-12-05 Publication of BR9207024A publication Critical patent/BR9207024A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Genetics & Genomics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Virology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)

BR9207024A 1992-01-06 1992-12-03 Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone BR9207024A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US81723592A	1992-01-06	1992-01-06
PCT/US1992/010189 WO1993014215A1 (en)	1992-01-06	1992-12-03	Process and uses for 4,5-dihydrogeldanamycin and its hydroquinone

Publications (1)

Publication Number	Publication Date
BR9207024A true BR9207024A (en)	1995-12-05

Family

ID=25222638

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9207024A BR9207024A (en)	1992-01-06	1992-12-03	Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone

Country Status (15)

Country	Link
JP (1)	JPH06510913A (en)
KR (1)	KR940703923A (en)
CN (1)	CN1074937A (en)
AU (1)	AU3225693A (en)
BR (1)	BR9207024A (en)
CA (1)	CA2127457A1 (en)
CZ (1)	CZ390592A3 (en)
FI (1)	FI943207A7 (en)
HU (1)	HU9401936D0 (en)
IL (1)	IL104289A0 (en)
MX (1)	MX9300011A (en)
NO (1)	NO942532L (en)
PT (1)	PT101169A (en)
WO (1)	WO1993014215A1 (en)
ZA (1)	ZA9333B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0706516A1 (en) *	1993-06-29	1996-04-17	Pfizer Inc.	Ansamycin derivatives as antioncogene and anticancer agents
US5932566A (en) *	1994-06-16	1999-08-03	Pfizer Inc.	Ansamycin derivatives as antioncogene and anticancer agents
US6852496B1 (en)	1997-08-12	2005-02-08	Oregon Health And Science University	Methods of screening for agents that promote nerve cell growth
US6872715B2 (en)	2001-08-06	2005-03-29	Kosan Biosciences, Inc.	Benzoquinone ansamycins
EP1923061A1 (en)	2001-09-24	2008-05-21	Conforma Therapeutic Corporation	Process for preparing 17-Allyl amino geldanamycin (17-AAG) and other ansamycins
US7579462B2 (en)	2001-09-24	2009-08-25	Conforma Therapeutics Corporation	Process for preparing 17-allyl amino geldanamycin (17-aag) and other ansamycins
DE60327994D1 (en)	2002-02-08	2009-07-30	Conforma Therapeutics Corp	ANSAMYCINE WITH IMPROVED PHARMACOLOGICAL AND BIOLOGICAL PROPERTIES
TW200303363A (en) *	2002-02-25	2003-09-01	Upjohn Co	Process to prepare and isolate geldanamycin
US7241754B2 (en)	2003-06-13	2007-07-10	Kosan Biosciences, Inc.	2-Desmethyl ansamycin compounds
US6855705B1 (en)	2003-11-12	2005-02-15	Kosan Biosciences, Inc.	11-O-methylgeldanamycin compounds
US6875863B1 (en)	2003-11-12	2005-04-05	Kosan Biosciences, Inc.	11-O-methylgeldanamycin compounds
US6887993B1 (en)	2003-11-12	2005-05-03	Kosan Biosciences, Inc.	11-O-methylgeldanamycin compounds
US6870049B1 (en)	2003-11-12	2005-03-22	Kosan Biosciences, Inc.	11-O-methylgeldanamycin compounds
US20050148496A1 (en) *	2003-11-26	2005-07-07	Entelos, Inc.	Treatment of rheumatoid arthritis with hypoxia inducible factor-1alpha antagonists
ZA200604863B (en) *	2003-12-23	2007-12-27	Infinity Pharmaceuticals Inc	Analogs of benzoquinone-containing ansamycins for the treatment of cancer
DK1716119T3 (en) *	2003-12-23	2013-06-10	Infinity Discovery Inc	ANALOGS OF BENZOQUINON-CONTAINING ANAMICYCINES FOR TREATMENT OF CANCER
US20060019941A1 (en) *	2003-12-23	2006-01-26	Infinity Pharmaceuticals, Inc.	Analogs of benzoquinone-containing ansamycins and methods of use thereof
KR20080004550A (en)	2005-03-30	2008-01-09	콘포마 세러퓨틱스 코포레이션	Alkynyl pyrrolopyrimidines and related analogs as HPSPO-inhibitors
MX2009004775A (en) *	2006-11-09	2009-05-21	Biotica Tech Ltd	Novel compounds and methods for their production.
PE20081506A1 (en)	2006-12-12	2008-12-09	Infinity Discovery Inc	ANSAMYCIN FORMULATIONS
CN100500668C (en) *	2006-12-19	2009-06-17	中国人民解放军军事医学科学院毒物药物研究所	Geldanamycin derivative and its preparing method and use for preparing medicine
EP2121957A4 (en)	2007-01-26	2010-11-10	Kosan Biosciences Inc	Macrolactams by engineered biosynthesis
EP2297109A4 (en) *	2008-04-21	2011-06-22	Biocon Ltd	A process for isolation and purification of geldanamycin
WO2010045442A1 (en)	2008-10-15	2010-04-22	Infinity Discovery, Inc.	Ansamycin hydroquinone compositions
CN102030764B (en) *	2010-11-12	2012-07-04	中国医学科学院医药生物技术研究所	4,5-dihydro-thiazinogeldanamycin and preparation method thereof
CN103305563B (en) *	2013-06-14	2014-12-03	湖南农业大学	Method for extracting alisamycin from streptomyces

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3595955A (en) *	1969-03-26	1971-07-27	Upjohn Co	Geldanamycin and process for producing same

1992
- 1992-12-03 FI FI943207A patent/FI943207A7/en unknown
- 1992-12-03 WO PCT/US1992/010189 patent/WO1993014215A1/en not_active Ceased
- 1992-12-03 CA CA002127457A patent/CA2127457A1/en not_active Abandoned
- 1992-12-03 HU HU9401936A patent/HU9401936D0/en unknown
- 1992-12-03 AU AU32256/93A patent/AU3225693A/en not_active Abandoned
- 1992-12-03 BR BR9207024A patent/BR9207024A/en not_active Application Discontinuation
- 1992-12-03 JP JP5512423A patent/JPH06510913A/en active Pending
- 1992-12-03 KR KR1019940702334A patent/KR940703923A/en not_active Ceased
- 1992-12-15 CN CN92113885A patent/CN1074937A/en active Pending
- 1992-12-28 CZ CS923905A patent/CZ390592A3/en unknown
- 1992-12-31 IL IL104289A patent/IL104289A0/en unknown
1993
- 1993-01-04 PT PT101169A patent/PT101169A/en not_active Application Discontinuation
- 1993-01-05 MX MX9300011A patent/MX9300011A/en unknown
- 1993-01-05 ZA ZA9333A patent/ZA9333B/en unknown
1994
- 1994-07-05 NO NO942532A patent/NO942532L/en unknown

Also Published As

Publication number	Publication date
CA2127457A1 (en)	1993-07-22
FI943207L (en)	1994-07-05
NO942532D0 (en)	1994-07-05
HU9401936D0 (en)	1994-09-28
KR940703923A (en)	1994-12-12
AU3225693A (en)	1993-08-03
ZA9333B (en)	1994-07-05
MX9300011A (en)	1993-12-01
NO942532L (en)	1994-07-05
WO1993014215A1 (en)	1993-07-22
FI943207A0 (en)	1994-07-05
PT101169A (en)	1994-03-31
CN1074937A (en)	1993-08-04
IL104289A0 (en)	1993-05-13
FI943207A7 (en)	1994-07-05
JPH06510913A (en)	1994-12-08
CZ390592A3 (en)	1993-08-11

Publication	Publication Date	Title
BR9207024A (en)	1995-12-05	Process and uses for 4,5-DI-hydrogeldanamycin and its hydroquinone
BR9103195A (en)	1992-05-05	COMPOUND AND PROCESS FOR ITS PREPARATION
BR9302680A (en)	1994-02-08	PROCESS FOR HYDROFORMILATION TO PRODUCE 1,6-HEXANODIALS
FI961430L (en)	1996-03-29	Process I
BR9200100A (en)	1992-10-06	PROCESS FOR SIMULTANEOUS SACARIFICATION AND FERMENTATION
BR9300739A (en)	1993-09-28	HYDRO-METALURGICAL PROCESS FOR OBTAINING TANTALO AND NIOBIO
BR9305296A (en)	1994-08-16	Sump and process for its manufacture
BR9200333A (en)	1992-10-13	PISTON AND PROCESS FOR YOUR MANUFACTURE
BR9303456A (en)	1994-03-22	COMPOUNDS, PROCESS FOR PREPARATION, DRUGS, PROCESS FOR PREPARATION AND EMPLOYMENT
BR9302424A (en)	1994-01-11	POLYCARBONATE AND PROCESS FOR THE SAME PRODUCTION
BR9004194A (en)	1991-09-03	POLYISOCIANATES, MIXTURES, PROCESS FOR ITS PREPARATION AND EMPLOYMENT
BR9204547A (en)	1993-06-01	HYDROXYPYRIDONCARBOXAMIDES, THEIR PREPARATION AND APPLICATION PROCESS
BR9301448A (en)	1993-10-13	COMPOSITION AND PROCESS FOR ITS PREPARATION
BR9400338A (en)	1994-08-16	Process for the preparation of 1,1,1,2-tetrafluoro-2-chloroethane and pentafluorethane
BR9303670A (en)	1994-05-24	Multilayer material and process for its formation
BR9203964A (en)	1993-04-27	SOAP BAR AND PROCESS FOR ITS MANUFACTURING
BR9401483A (en)	1994-11-22	Compound and process for its preparation
BR9300034A (en)	1993-07-13	COMPOUND, PROCESS FOR ITS PRODUCTION AND HEALING COMPOSITION
BR9401490A (en)	1994-10-18	Shampoo composition and process for its production
BR9302104A (en)	1994-01-25	TRACTION BAR AND PROCESS FOR ITS CONSTRUCTION
FI934624A0 (en)	1993-10-20	ENANTIOMERA CIS-3- (4,6-DIHYDROXICROMAN-3-YLMETHYL) BENZOESYROR
BR9301466A (en)	1993-10-13	PROCESS FOR THE PREPARATION OF ENHANCING COMPOSITES, ENHANCING COMPOSITES, THEIR APPLICATION AND COMPOSITIONS
BR9100045A (en)	1991-10-22	PROCESS FOR THE PREPARATION OF 1,1,1,2,2-PENTAFLUORO-3,3-DICLOROPROPANO AND 1,1,2,2,3-PENTAFLUORO-1,3-DICLOROPROPANO
BR9301364A (en)	1993-10-13	POLYCARBONATE COPOLIMER AND PROCESS FOR ITS PRODUCTION
BR9103785A (en)	1992-05-19	COMPOUND AND PROCESS FOR ITS PREPARATION

Legal Events

Date	Code	Title	Description
1995-12-26	FA1	Application withdrawn (art. 18(2))