BR9207061A - Antagonistas de LTB4 á base de benzopirano e afins - Google Patents

Antagonistas de LTB4 á base de benzopirano e afins

Info

Publication number: BR9207061A
Authority: BR; Brazil
Prior art keywords: benzopyran; ltb4 antagonists; ltb4; antagonists; benzopyran based
Prior art date: 1992-01-23

Application number

BR9207061A

Other languages

English (en)

Inventor

Kevin Koch

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-23

Filing date

1992-11-13

Publication date

1995-12-26

1992-11-13 Application filed by Pfizer filed Critical Pfizer

1995-12-26 Publication of BR9207061A publication Critical patent/BR9207061A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrane Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Furan Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BR9207061A 1992-01-23 1992-11-13 Antagonistas de LTB4 á base de benzopirano e afins BR9207061A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US82441292A	1992-01-23	1992-01-23
PCT/US1992/009496 WO1993015067A1 (en)	1992-01-23	1992-11-13	Benzopyran and related ltb4 antagonists

Publications (1)

Publication Number	Publication Date
BR9207061A true BR9207061A (pt)	1995-12-26

Family

ID=25241346

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9207061A BR9207061A (pt)	1992-01-23	1992-11-13	Antagonistas de LTB4 á base de benzopirano e afins

Country Status (36)

Country	Link
US (2)	US5552435A (pt)
EP (1)	EP0623123B1 (pt)
JP (1)	JP2765757B2 (pt)
KR (2)	KR0124802B1 (pt)
CN (1)	CN1041311C (pt)
AP (1)	AP352A (pt)
AT (1)	ATE152108T1 (pt)
AU (1)	AU666896B2 (pt)
BG (1)	BG62331B1 (pt)
BR (1)	BR9207061A (pt)
CA (1)	CA2126752C (pt)
CZ (1)	CZ282400B6 (pt)
DE (1)	DE69219364T2 (pt)
DK (1)	DK0623123T3 (pt)
EG (1)	EG20202A (pt)
FI (1)	FI943474A0 (pt)
GR (1)	GR3023657T3 (pt)
HU (1)	HU221194B1 (pt)
IL (1)	IL104386A (pt)
IS (1)	IS1795B (pt)
MX (1)	MX9300312A (pt)
MY (1)	MY109144A (pt)
NO (1)	NO306508B1 (pt)
NZ (1)	NZ245735A (pt)
OA (1)	OA11456A (pt)
PH (1)	PH30346A (pt)
PL (1)	PL171003B1 (pt)
PT (1)	PT101183B (pt)
RO (1)	RO112031B1 (pt)
RU (1)	RU2114110C1 (pt)
SG (1)	SG49813A1 (pt)
SK (1)	SK280451B6 (pt)
TW (1)	TW213907B (pt)
WO (1)	WO1993015067A1 (pt)
YU (1)	YU48949B (pt)
ZA (1)	ZA93486B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2084547B1 (es) *	1993-07-12	1997-01-16	Pfizer	Antagonistas benzopiranicos y relacionados de leucotrieno b4.
NZ285156A (en) *	1994-10-13	1999-01-28	Pfizer	Benzopyran and benzo-fused compounds, preparation and use as leukotriene b4 antagonists (ltb4)
CN1166834A (zh)	1994-10-13	1997-12-03	美国辉瑞有限公司	苯并吡喃和苯并稠合化合物，其制备方法和它们作为白三烯b4(ltb4)拮抗剂的用途
EP0925292B1 (en) *	1996-09-16	2003-09-10	Pfizer Inc.	Processes and intermediates for preparing substituted chromanol derivatives
US6416733B1 (en)	1996-10-07	2002-07-09	Bristol-Myers Squibb Pharma Company	Radiopharmaceuticals for imaging infection and inflammation
IL121931A (en) *	1996-10-17	2000-02-17	Pfizer	Pharmaceutical compositions for preventing allograft rejection
EP0963755A3 (en) *	1998-04-16	2001-03-14	Pfizer Products Inc.	Use of benzopyranes for preventing allograft rejection
US6436987B1 (en) *	2000-06-08	2002-08-20	Pfizer Inc.	Crystalline forms of (3S-trans)-2-[3,4-dihydro-4-hydroxy-3-(phenylmethyl)-2H-1-benzopyran-7-yl]-4-(trifluoromethyl)-benzoic acid
CA2427911A1 (en)	2000-11-03	2002-05-10	Bristol Myers Squibb Company	Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation
JP2004518685A (ja) *	2001-01-30	2004-06-24	ファイザー・プロダクツ・インク	クロマニル安息香酸の調製方法
AU4239302A (en) *	2001-06-28	2003-01-02	Pfizer Products Inc.	Benzoic acid substituted benzopyrans for the treatment of atherosclerosis
WO2006011048A1 (en) *	2004-07-22	2006-02-02	Pharmacia Corporation	Compositions for treatment of inflammation and pain using a combination of a cox-2 selective inhibitor and a ltb4 receptor antagonist
WO2017095722A1 (en)	2015-11-30	2017-06-08	Merck Sharp & Dohme Corp.	Aryl acylsulfonamides as blt1 antagonists
US10370368B2 (en)	2015-11-30	2019-08-06	Merck Sharp & Dohme Corp.	Aryl acylsulfonamides as BLT1 antagonists
US20190382363A1 (en)	2015-11-30	2019-12-19	Merck Sharp & Dohme Corp.	Aryl sulfonamides as blt1 antagonists
US10450309B2 (en)	2015-11-30	2019-10-22	Merch Sharp & Dohme Corp.	Aryl sulfonamides as BLT1 antagonists

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2309282A1 (de) *	1973-02-24	1974-08-29	Hoechst Ag	Verfahren zur herstellung von 4-hydroxy-thiochromanen
DE2745305A1 (de) *	1977-10-07	1979-04-19	Bayer Ag	Insektizide und akarizide mittel
US4565882A (en) *	1984-01-06	1986-01-21	G. D. Searle & Co.	Substituted dihydrobenzopyran-2-carboxylates
CA1320490C (en) *	1987-01-12	1993-07-20	Darrel M. Gapinski	Anti-inflammatory agents
JPS63292977A (ja) *	1987-05-25	1988-11-30	片山　晋	スキ−用のビンディング固定板
US5059609A (en) *	1987-10-19	1991-10-22	Pfizer Inc.	Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases
MX13485A (es) *	1987-10-19	1993-05-01	Pfizer	Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
WO1990012010A1 (en) *	1989-04-07	1990-10-18	Pfizer Inc.	Substituted chromans in the treatment of asthma, arthritis and related diseases
WO1990015801A1 (en) *	1989-06-22	1990-12-27	Pfizer Inc.	Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases
WO1991012253A1 (en) *	1990-02-07	1991-08-22	Pfizer Inc.	Tetralin and chroman derivatives useful in the treatment of asthma, arthritis, and related diseases
WO1993015066A1 (en) *	1992-01-23	1993-08-05	Pfizer Inc.	Benzopyran and related ltb4 antagonists
EP0558245A1 (en) *	1992-02-25	1993-09-01	RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY	Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors
FR2693196B1 (fr) *	1992-07-03	1994-12-23	Lipha	Dérivés de benzopyranone ou de benzothiopyranone, procédé de préparation et composition pharmaceutique les contenant.

1992
- 1992-01-22 MX MX9300312A patent/MX9300312A/es not_active IP Right Cessation
- 1992-11-13 AU AU30650/92A patent/AU666896B2/en not_active Ceased
- 1992-11-13 DK DK92924284.0T patent/DK0623123T3/da active
- 1992-11-13 RO RO94-01220A patent/RO112031B1/ro unknown
- 1992-11-13 RU RU94035964/04A patent/RU2114110C1/ru not_active IP Right Cessation
- 1992-11-13 CA CA002126752A patent/CA2126752C/en not_active Expired - Lifetime
- 1992-11-13 SK SK844-94A patent/SK280451B6/sk unknown
- 1992-11-13 SG SG1996006699A patent/SG49813A1/en unknown
- 1992-11-13 KR KR1019940702518A patent/KR0124802B1/ko not_active Expired - Fee Related
- 1992-11-13 PL PL92304689A patent/PL171003B1/pl unknown
- 1992-11-13 FI FI943474A patent/FI943474A0/fi not_active IP Right Cessation
- 1992-11-13 HU HU9401979A patent/HU221194B1/hu not_active IP Right Cessation
- 1992-11-13 DE DE69219364T patent/DE69219364T2/de not_active Expired - Lifetime
- 1992-11-13 US US08/295,827 patent/US5552435A/en not_active Expired - Lifetime
- 1992-11-13 JP JP5513184A patent/JP2765757B2/ja not_active Expired - Lifetime
- 1992-11-13 AT AT92924284T patent/ATE152108T1/de not_active IP Right Cessation
- 1992-11-13 BR BR9207061A patent/BR9207061A/pt not_active Application Discontinuation
- 1992-11-13 EP EP92924284A patent/EP0623123B1/en not_active Expired - Lifetime
- 1992-11-13 WO PCT/US1992/009496 patent/WO1993015067A1/en not_active Ceased
- 1992-11-13 CZ CZ941762A patent/CZ282400B6/cs not_active IP Right Cessation
- 1992-11-17 TW TW081109200A patent/TW213907B/zh active
- 1992-11-20 AP APAP/P/1992/000449A patent/AP352A/en active
1993
- 1993-01-02 EG EG3293A patent/EG20202A/xx active
- 1993-01-13 PH PH45558D patent/PH30346A/en unknown
- 1993-01-14 IL IL10438693A patent/IL104386A/en not_active IP Right Cessation
- 1993-01-19 MY MYPI93000086A patent/MY109144A/en unknown
- 1993-01-19 IS IS3969A patent/IS1795B/is unknown
- 1993-01-21 CN CN93100769A patent/CN1041311C/zh not_active Expired - Fee Related
- 1993-01-22 NZ NZ245735A patent/NZ245735A/en unknown
- 1993-01-22 ZA ZA93486A patent/ZA93486B/xx unknown
- 1993-01-22 PT PT101183A patent/PT101183B/pt not_active IP Right Cessation
- 1993-01-22 YU YU3393A patent/YU48949B/sh unknown
1994
- 1994-06-21 BG BG98867A patent/BG62331B1/bg unknown
- 1994-07-22 KR KR1019940702518A patent/KR950700273A/ko active Granted
- 1994-07-22 NO NO942759A patent/NO306508B1/no not_active IP Right Cessation
- 1994-07-22 OA OA60543A patent/OA11456A/en unknown
1996
- 1996-05-03 US US08/642,711 patent/US5684046A/en not_active Expired - Lifetime
1997
- 1997-06-04 GR GR970401301T patent/GR3023657T3/el unknown

Also Published As

Publication number	Publication date
CN1041311C (zh)	1998-12-23
FI943474A7 (fi)	1994-07-22
SK84494A3 (en)	1995-05-10
JPH07502536A (ja)	1995-03-16
CZ176294A3 (en)	1995-02-15
EP0623123B1 (en)	1997-04-23
DK0623123T3 (da)	1997-10-13
SG49813A1 (en)	1998-06-15
KR950700273A (ko)	1995-01-16
DE69219364D1 (de)	1997-05-28
US5684046A (en)	1997-11-04
IL104386A (en)	2001-05-20
HU9401979D0 (en)	1994-09-28
FI943474L (fi)	1994-07-22
US5552435A (en)	1996-09-03
TW213907B (pt)	1993-10-01
JP2765757B2 (ja)	1998-06-18
YU3393A (sh)	1996-07-24
IL104386A0 (en)	1993-05-13
RO112031B1 (ro)	1997-04-30
ZA93486B (en)	1994-07-22
ATE152108T1 (de)	1997-05-15
PT101183B (pt)	1999-09-30
WO1993015067A1 (en)	1993-08-05
YU48949B (sh)	2003-01-31
PT101183A (pt)	1994-03-31
PH30346A (en)	1997-04-02
IS1795B (is)	2001-12-18
SK280451B6 (sk)	2000-02-14
HK1000245A1 (en)	1998-02-13
AP9200449A0 (en)	1993-01-31
BG62331B1 (bg)	1999-08-31
GR3023657T3 (en)	1997-09-30
HU221194B1 (en)	2002-08-28
AP352A (en)	1994-08-10
MY109144A (en)	1996-12-31
DE69219364T2 (de)	1997-08-07
EP0623123A1 (en)	1994-11-09
CN1075318A (zh)	1993-08-18
NO942759D0 (no)	1994-07-22
CZ282400B6 (cs)	1997-07-16
MX9300312A (es)	1993-07-31
AU3065092A (en)	1993-09-01
RU2114110C1 (ru)	1998-06-27
FI943474A0 (fi)	1994-07-22
HUT68790A (en)	1995-07-28
IS3969A (is)	1993-07-24
NZ245735A (en)	1995-04-27
EG20202A (en)	1997-10-30
NO306508B1 (no)	1999-11-15
RU94035964A (ru)	1997-05-27
KR0124802B1 (ko)	1997-11-25
CA2126752C (en)	2000-05-16
NO942759L (no)	1994-07-22
AU666896B2 (en)	1996-02-29
OA11456A (en)	2003-11-18
PL171003B1 (pl)	1997-02-28
CA2126752A1 (en)	1993-08-05
BG98867A (bg)	1995-03-31

Publication	Publication Date	Title
FI960079L (fi)	1996-01-08	Kuppi
DE69411322D1 (de)	1998-08-06	Verbinder
DE69405782D1 (de)	1997-10-30	Verbinder
EE9600122A (et)	1997-04-15	Infuuser
DE69000467D1 (de)	1992-12-24	Bis-aza-bicyclische anxiolytica und antidepressiva.
BR9207064A (pt)	1995-12-19	Antagonistas de LTB4 à base de benzopiranos e relacionados
FI950908A0 (fi)	1995-02-28	Antitussiivi
BR9207061A (pt)	1995-12-26	Antagonistas de LTB4 á base de benzopirano e afins
DE69408554D1 (de)	1998-03-26	Verbinder
DE69420234D1 (de)	1999-09-30	Verbinder
DE69413911D1 (de)	1998-11-19	Verbinder
DE69011337D1 (de)	1994-09-08	Polyhalodihydrodioxine und polyhalodioxole.
DE69310773D1 (de)	1997-06-19	Verbinder
KR960003881U (ko)	1996-02-14	휴대용 컵
BR9507459A (pt)	1997-11-11	Antagonistas á base de piridino-leucotrieno b4 substituído
KR920020739U (ko)	1992-12-18	휴대용 컵
KR950026480U (ko)	1995-10-16	휴대용 컵
ATE104289T1 (de)	1994-04-15	Aminoethylthiazole und aminoethyloxazol-derivate.
KR940026096U (ko)	1994-12-08	이중컵
SE9301143D0 (sv)	1993-04-06	Silverfisken
KR940021936U (ko)	1994-10-19	이남박
FI955373A0 (fi)	1995-11-08	Saumarakenne
IT8943535A0 (it)	1989-10-05	Il cubotto
ITMI930344V0 (it)	1993-04-28	La palla-parola
IT8911310V0 (it)	1989-06-01	Il ricordatore elettronico

Legal Events

Date	Code	Title	Description
1996-04-02	EE	Request for examination
1998-01-21	FA	Application withdrawn