BR9204851A - Antigeno de HIV e processo para sua produçao molécula de DNA recombinante, reagente para diagnóstico e vacina para sindrome da imunodeficiência adquirida - Google Patents
Antigeno de HIV e processo para sua produçao molécula de DNA recombinante, reagente para diagnóstico e vacina para sindrome da imunodeficiência adquiridaInfo
- Publication number
- BR9204851A BR9204851A BR9204851A BR9204851A BR9204851A BR 9204851 A BR9204851 A BR 9204851A BR 9204851 A BR9204851 A BR 9204851A BR 9204851 A BR9204851 A BR 9204851A BR 9204851 A BR9204851 A BR 9204851A
- Authority
- BR
- Brazil
- Prior art keywords
- gag
- hiv antigen
- env
- vaccine
- diagnostic reagent
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 6
- 102000036639 antigens Human genes 0.000 title abstract 6
- 108091007433 antigens Proteins 0.000 title abstract 6
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 3
- 208000030507 AIDS Diseases 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 102000053602 DNA Human genes 0.000 title 1
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 101710177291 Gag polyprotein Proteins 0.000 abstract 1
- 101710125418 Major capsid protein Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108700004026 gag Genes Proteins 0.000 abstract 1
- 101150098622 gag gene Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/974—Aids related test
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17027092 | 1992-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9204851A true BR9204851A (pt) | 1994-06-07 |
Family
ID=15901829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9204851A BR9204851A (pt) | 1992-06-04 | 1992-12-04 | Antigeno de HIV e processo para sua produçao molécula de DNA recombinante, reagente para diagnóstico e vacina para sindrome da imunodeficiência adquirida |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5576421A (pt) |
| EP (1) | EP0572737B1 (pt) |
| KR (1) | KR0143977B1 (pt) |
| CN (1) | CN1079509A (pt) |
| AT (1) | ATE199394T1 (pt) |
| BR (1) | BR9204851A (pt) |
| CA (1) | CA2084386C (pt) |
| DE (1) | DE69231705T2 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2178635C (en) * | 1993-12-10 | 2004-05-25 | Yu-Wen Hu | Immunofluorescence assay for the detection of antibodies using recombinant antigens in insoluble form |
| DE4411718A1 (de) * | 1994-04-05 | 1995-10-12 | Gsf Forschungszentrum Umwelt | RFB-Retrovirusgenom |
| EP0907740A1 (en) * | 1997-01-02 | 1999-04-14 | Universidade Federal De Minas Gerais | THE PROCESS FOR EXPRESSION AND PRODUCTION OF RECOMBINANT PROTEIN HYBRID PROTEIN (p24/p17) DERIVED FROM HUMAN IMMUNODEFICIENCY VIRUSES (HIV-1) |
| US6271354B1 (en) | 1997-04-03 | 2001-08-07 | Thomas Jefferson University | Chimeric viral proteins |
| ES2341429T3 (es) * | 1999-12-23 | 2010-06-21 | Medical Research Council | Mejoras en las respuestas inmunitarias al vih o relacionadas con las mismas. |
| EP2280074A3 (en) * | 2001-07-05 | 2011-06-22 | Novartis Vaccines and Diagnostics, Inc. | Polynucleotides encoding antigenic HIV type B and/or type C polypeptides, polypeptides and uses thereof |
| US7611712B2 (en) * | 2003-10-23 | 2009-11-03 | Nelson M. Karp | Immunogenic compositions capable of eliciting Th1 immune responses comprising an HIV-1 MA myristate binding site polypeptide |
| FR2874612A1 (fr) * | 2004-08-27 | 2006-03-03 | Commissariat Energie Atomique | Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications |
| AU2005335203A1 (en) * | 2004-09-08 | 2007-02-15 | The United States Of America As Represented By The Secretary Of Health And Human Services, Nih | Compositions and methods for the detection of HIV-1/HIV-2 infection |
| KR101138930B1 (ko) * | 2007-02-16 | 2012-04-25 | (주) 에빅스젠 | Hⅰv nc 단백질을 포함하는 aⅰds 예방 및 치료용조성물 |
| CN101475642B (zh) * | 2008-11-07 | 2013-06-05 | 深圳市菲鹏生物股份有限公司 | 一种艾滋病毒重组抗原及其融合蛋白 |
| KR102079761B1 (ko) * | 2018-05-14 | 2020-02-20 | 서울대학교산학협력단 | pMyong2 벡터 시스템을 이용하여 HIV-1 p24를 발현하는 재조합 BCG 및 이의 HIV-1 백신으로의 이용 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0227169B1 (en) * | 1985-12-17 | 1993-03-17 | Akzo N.V. | Immunochemical reagent |
| US4925784A (en) * | 1986-04-04 | 1990-05-15 | Hoffmann-La Roche Inc. | Expression and purification of an HTLV-III gag/env gene protein |
| NZ226026A (en) * | 1987-09-04 | 1991-03-26 | Wellcome Found | Immunoassay for an antibody using recombinant antigens expressed in two different genera |
| JPH01179687A (ja) * | 1987-12-30 | 1989-07-17 | Chemo Sero Therapeut Res Inst | Hiv融合蛋白質 |
| IL90048A0 (en) * | 1988-04-25 | 1989-12-15 | Merck & Co Inc | Recombinant gag precursor of hiv,its preparation and its use as aids vaccine |
| DE68917520T2 (de) * | 1988-05-06 | 1995-01-05 | Ferropas Ag | Verfahren und Systeme zur Herstellung von HIV-Antigenen. |
| CA2003383A1 (en) * | 1988-11-23 | 1990-05-23 | Sushil G. Devare | Synthetic dna derived recombinant hiv antigens |
| JPH04500308A (ja) | 1989-05-17 | 1992-01-23 | リサーチ・コーポレーション・テクノロジーズ・インコーポレーテッド | 組換え型生成物のレトロウィルス媒介分泌 |
| ES2140380T5 (es) * | 1990-03-21 | 2005-03-16 | Geneart Gmbh | Secuencias de adn que codifican polipeptidos gag retroviricos modificados y vacunas que las contienen o agregados de las mismas. |
-
1992
- 1992-12-02 EP EP92311006A patent/EP0572737B1/en not_active Expired - Lifetime
- 1992-12-02 AT AT92311006T patent/ATE199394T1/de not_active IP Right Cessation
- 1992-12-02 DE DE69231705T patent/DE69231705T2/de not_active Expired - Fee Related
- 1992-12-02 CA CA002084386A patent/CA2084386C/en not_active Expired - Fee Related
- 1992-12-04 BR BR9204851A patent/BR9204851A/pt not_active Application Discontinuation
- 1992-12-04 KR KR1019920023362A patent/KR0143977B1/ko not_active Expired - Fee Related
- 1992-12-04 CN CN92115396A patent/CN1079509A/zh active Pending
-
1995
- 1995-01-18 US US08/375,510 patent/US5576421A/en not_active Expired - Fee Related
- 1995-06-07 US US08/487,657 patent/US5834267A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0572737A2 (en) | 1993-12-08 |
| KR940000117A (ko) | 1994-01-03 |
| DE69231705T2 (de) | 2001-10-18 |
| ATE199394T1 (de) | 2001-03-15 |
| DE69231705D1 (de) | 2001-04-05 |
| KR0143977B1 (ko) | 1998-07-15 |
| US5576421A (en) | 1996-11-19 |
| US5834267A (en) | 1998-11-10 |
| EP0572737A3 (en) | 1994-11-23 |
| CA2084386A1 (en) | 1993-12-05 |
| CN1079509A (zh) | 1993-12-15 |
| CA2084386C (en) | 2001-02-20 |
| EP0572737B1 (en) | 2001-02-28 |
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| ES2140380T3 (es) | Secuencias de adn que codifican polipeptidos gag retroviricos modificados y vacunas que las contienen o agregados de las mismas. | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA1 | Application withdrawn (art. 18(2)) | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: C07K 14/005 (2006.01), A61K 39/00 (2006.0 |