BR9201451A - N-hidroxi-n-(3-(2-fenil-substituido)pro-2-enil)ureias e tioureias,formulacao farmaceutica,processos para inbir 5-lipoxigenase e para tratar asma - Google Patents
N-hidroxi-n-(3-(2-fenil-substituido)pro-2-enil)ureias e tioureias,formulacao farmaceutica,processos para inbir 5-lipoxigenase e para tratar asmaInfo
- Publication number
- BR9201451A BR9201451A BR929201451A BR9201451A BR9201451A BR 9201451 A BR9201451 A BR 9201451A BR 929201451 A BR929201451 A BR 929201451A BR 9201451 A BR9201451 A BR 9201451A BR 9201451 A BR9201451 A BR 9201451A
- Authority
- BR
- Brazil
- Prior art keywords
- thioureues
- enil
- lipoxygenase
- ureas
- pro
- Prior art date
Links
- 102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 title 1
- 108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 title 1
- 208000006673 asthma Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003672 ureas Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/690,131 US5130485A (en) | 1991-04-23 | 1991-04-23 | N-hydroxy-N-(3-(2-substituted phenyl)prop-2-enyl)ureas and thioureas useful as 5-lipoxygenase inhibiting agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9201451A true BR9201451A (pt) | 1992-12-01 |
Family
ID=24771221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR929201451A BR9201451A (pt) | 1991-04-23 | 1992-04-20 | N-hidroxi-n-(3-(2-fenil-substituido)pro-2-enil)ureias e tioureias,formulacao farmaceutica,processos para inbir 5-lipoxigenase e para tratar asma |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5130485A (pt) |
| EP (1) | EP0510947A1 (pt) |
| JP (1) | JPH05148218A (pt) |
| KR (1) | KR920019739A (pt) |
| CN (1) | CN1066060A (pt) |
| AU (1) | AU647911B2 (pt) |
| BR (1) | BR9201451A (pt) |
| CA (1) | CA2066509A1 (pt) |
| CS (1) | CS119592A3 (pt) |
| FI (1) | FI921785A7 (pt) |
| HU (1) | HU209794B (pt) |
| IE (1) | IE921280A1 (pt) |
| IL (1) | IL101624A0 (pt) |
| MX (1) | MX9201809A (pt) |
| NO (1) | NO921529L (pt) |
| NZ (1) | NZ242427A (pt) |
| TW (1) | TW215081B (pt) |
| YU (1) | YU42592A (pt) |
| ZA (1) | ZA922872B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283361A (en) * | 1991-04-23 | 1994-02-01 | Eli Lilly And Company | N-hydroxy-N-[3-[2-(halophenylthio)phenyl]prop-2-enyl]ureas as lipoxygenase inhibitors |
| US5288743A (en) * | 1992-11-20 | 1994-02-22 | Abbott Laboratories | Indole carboxylate derivatives which inhibit leukotriene biosynthesis |
| TW418089B (en) * | 1993-08-19 | 2001-01-11 | Pfizer | Pharmaceutical composition comprising phenoxyphenyl cyclopentenyl hydroxyureas (the dextrorotary isomers) |
| US5891460A (en) * | 1995-06-07 | 1999-04-06 | University Of Southern California University Park Campus | Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof |
| US20120093922A1 (en) | 2009-04-29 | 2012-04-19 | Amarin Corporation Plc | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| US11724991B1 (en) * | 2023-01-06 | 2023-08-15 | King Faisal University | Selective 5-LO inhibitors for the treatment of bronchial asthma |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI89709C (fi) * | 1985-03-16 | 1993-11-10 | Wellcome Found | Foerfarande foer framstaellning av terapeutiskt anvaendbara arylderivat |
| IE59397B1 (en) * | 1985-03-16 | 1994-02-23 | Wellcome Found | New aryl derivatives |
| GB8619593D0 (en) * | 1986-08-12 | 1986-09-24 | Roussel Lab Ltd | Chemical compounds |
| EP0279263B1 (en) * | 1987-02-10 | 1993-08-04 | Abbott Laboratories | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds |
| US4897422A (en) * | 1987-02-10 | 1990-01-30 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
| EP0292699B1 (en) * | 1987-04-24 | 1994-03-23 | Abbott Laboratories | Urea based lipoxygenase inhibiting compounds |
| DK0384594T3 (da) * | 1989-02-03 | 1993-12-06 | Wellcome Found | Antiinflammatoriske arylderivater |
| WO1990012008A1 (en) * | 1989-03-30 | 1990-10-18 | Abbott Laboratories | Urea based lipoxygenase inhibiting compounds |
-
1991
- 1991-04-23 US US07/690,131 patent/US5130485A/en not_active Expired - Lifetime
-
1992
- 1992-04-16 IL IL101624A patent/IL101624A0/xx unknown
- 1992-04-17 TW TW081103010A patent/TW215081B/zh active
- 1992-04-17 CS CS921195A patent/CS119592A3/cs unknown
- 1992-04-20 BR BR929201451A patent/BR9201451A/pt not_active Application Discontinuation
- 1992-04-20 MX MX9201809A patent/MX9201809A/es unknown
- 1992-04-21 ZA ZA922872A patent/ZA922872B/xx unknown
- 1992-04-21 CA CA002066509A patent/CA2066509A1/en not_active Abandoned
- 1992-04-21 AU AU15016/92A patent/AU647911B2/en not_active Ceased
- 1992-04-21 KR KR1019920006702A patent/KR920019739A/ko not_active Withdrawn
- 1992-04-21 NO NO92921529A patent/NO921529L/no unknown
- 1992-04-22 HU HU9201342A patent/HU209794B/hu not_active IP Right Cessation
- 1992-04-22 IE IE128092A patent/IE921280A1/en not_active Application Discontinuation
- 1992-04-22 NZ NZ242427A patent/NZ242427A/en unknown
- 1992-04-22 EP EP92303614A patent/EP0510947A1/en not_active Ceased
- 1992-04-22 YU YU42592A patent/YU42592A/sh unknown
- 1992-04-22 JP JP4102844A patent/JPH05148218A/ja not_active Withdrawn
- 1992-04-22 CN CN92102893A patent/CN1066060A/zh active Pending
- 1992-04-22 FI FI921785A patent/FI921785A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ242427A (en) | 1993-11-25 |
| IE921280A1 (en) | 1992-11-04 |
| MX9201809A (es) | 1994-05-31 |
| IL101624A0 (en) | 1992-12-30 |
| KR920019739A (ko) | 1992-11-19 |
| US5130485A (en) | 1992-07-14 |
| CA2066509A1 (en) | 1992-10-24 |
| NO921529L (no) | 1992-10-26 |
| YU42592A (sh) | 1995-01-31 |
| NO921529D0 (no) | 1992-04-21 |
| CN1066060A (zh) | 1992-11-11 |
| HUT61978A (en) | 1993-03-29 |
| HU209794B (en) | 1994-11-28 |
| AU647911B2 (en) | 1994-03-31 |
| FI921785A0 (fi) | 1992-04-22 |
| AU1501692A (en) | 1992-10-29 |
| FI921785A7 (fi) | 1992-10-24 |
| CS119592A3 (en) | 1992-12-16 |
| HU9201342D0 (en) | 1992-07-28 |
| TW215081B (pt) | 1993-10-21 |
| EP0510947A1 (en) | 1992-10-28 |
| ZA922872B (en) | 1993-10-21 |
| JPH05148218A (ja) | 1993-06-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9302737A (pt) | Derivados de tiazolivinilfenila,processo para a preparacao de um composto,medicamento,uso e processos para tratar ou prevenir asma bronquica | |
| MX9202436A (es) | Composiciones para el cuidado del cabello y metodo para su preparacion. | |
| BR9408148A (pt) | Processo para tratamento de arritmia composto e formulação farmacêutica | |
| BR9203032A (pt) | Material esponjoso de liberacao lenta,processo para preparar o mesmo,preparacoes farmaceuticas e processo terapeutico | |
| ZA90394B (en) | Alkylated polyethylenimine derivatives,process for their preparation,their use as pharmaceuticals and pharmaceutical preparations | |
| BR9205142A (pt) | Composicao inseticida,e,processo para produzi-la | |
| FI940810L (fi) | Substituoidut bentseenisulfonyylivirtsa-aineet ja -tiovirtsa-aineet, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä | |
| FI950135A7 (fi) | Viljatuote, sen käyttötapa ja valmistusmenetelmä | |
| FI951817A7 (fi) | Orgonaluminoksituote, sen valmistus ja käyttö | |
| MX9202022A (es) | Derivados de pirazina y proceso para su preparacion. | |
| FI902248A7 (fi) | N-heteroaryyli-4-kinoliiniamiineja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä | |
| MX9102580A (es) | Nuevas benzodiacepinonas, procedimiento para su preparacion y composicion farmaceutica que las contiene. | |
| DE68904079D1 (de) | Walzwerk und walzwerkanlage. | |
| FI902850A7 (fi) | N-heteroaryylipuriini-6-amiineja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineina | |
| BR9408340A (pt) | Acido 5-acetamido-2,3,4,5-tetradeoxi-4-guanidino-d-glicero-d-glacto-não-2-enotiranosonico forma critalina processo para a preparação dos mesmos e formulação farmacêutica | |
| BR9100978A (pt) | Processos para preparar 1,1,1-trifluorocloroetano e 1,1,1,2-tetrafluoroetano | |
| BR9201451A (pt) | N-hidroxi-n-(3-(2-fenil-substituido)pro-2-enil)ureias e tioureias,formulacao farmaceutica,processos para inbir 5-lipoxigenase e para tratar asma | |
| MX9203836A (es) | Derivados de acido-4-amino-3-hidroxicarboxilico y proceso para su preparacion. | |
| DK581586A (da) | N-(pyrrol-l-yl)-pyridinaminer, deres fremstilling og anvendelse som laegemidler | |
| BR9204383A (pt) | Poliesteres e processos para preparar os mesmos | |
| DK0410358T3 (da) | Aromatiske carboxylsyreamider, deres fremstilling og deres anvendelse som lægemidler | |
| IT7950331A0 (it) | Composizione farmaceutica comprendente l-carnitina per il trattamento delle dislipidemie ed iperlipo proteinemie | |
| BR9201452A (pt) | Composto,formulacao farmaceutica e processos para inibir 5-lipoxigenase,para tratar asma e para preparar um composto | |
| FI895288A7 (fi) | 1,2,3,4-tetrahydro-1,9-akridiiniamiineja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä | |
| BR8803768A (pt) | Composicao odorante,processo para producao de compostos e uso dos ditos compostos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA1 | Application withdrawn (art. 18(2)) | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: PROCEDIMENTO AUTOMATICO DE RECLASSIFICACAO. AS CLASSIFICACOES IPC ANTERIORES ERAM: C07C 127/15; C07C 127/17; C07C 323/44; A61K 31/17. Ipc: C07C 335/40 (2006.01), C07C 275/64 (2006.01) Ipc: C07C 335/40 (2006.01), C07C 275/64 (2006.01) |