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BR112022009803A2 - Variantes de sacarose invertase - Google Patents

Variantes de sacarose invertase

Info

Publication number
BR112022009803A2
BR112022009803A2 BR112022009803A BR112022009803A BR112022009803A2 BR 112022009803 A2 BR112022009803 A2 BR 112022009803A2 BR 112022009803 A BR112022009803 A BR 112022009803A BR 112022009803 A BR112022009803 A BR 112022009803A BR 112022009803 A2 BR112022009803 A2 BR 112022009803A2
Authority
BR
Brazil
Prior art keywords
variants
sucrose invertase
sucrose
invertase
fructose
Prior art date
Application number
BR112022009803A
Other languages
English (en)
Inventor
Ko Nien-Hsi
Lau Wee Janice
A Hattendorf Douglas
Original Assignee
Corbion Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corbion Biotech Inc filed Critical Corbion Biotech Inc
Publication of BR112022009803A2 publication Critical patent/BR112022009803A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2431—Beta-fructofuranosidase (3.2.1.26), i.e. invertase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/12—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01026—Beta-fructofuranosidase (3.2.1.26), i.e. invertase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A presente revelação fornece variantes de sacarose invertase que têm uma habilidade melhorada para hidrolisar sacarose em glicose e frutose e métodos e composições relacionados.
BR112022009803A 2019-11-20 2020-11-19 Variantes de sacarose invertase BR112022009803A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962937849P 2019-11-20 2019-11-20
US202062961986P 2020-01-16 2020-01-16
PCT/US2020/061280 WO2021102139A1 (en) 2019-11-20 2020-11-19 Sucrose invertase variants

Publications (1)

Publication Number Publication Date
BR112022009803A2 true BR112022009803A2 (pt) 2022-08-16

Family

ID=73854898

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022009803A BR112022009803A2 (pt) 2019-11-20 2020-11-19 Variantes de sacarose invertase

Country Status (4)

Country Link
US (1) US12338468B2 (pt)
EP (1) EP4061936A1 (pt)
BR (1) BR112022009803A2 (pt)
WO (1) WO2021102139A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023305628A1 (en) * 2022-07-13 2025-01-16 Anagram Therapeutics, Inc. Methods and compositions for treating congenital sucrase-isomaltase deficiency
WO2025155915A1 (en) * 2024-01-17 2025-07-24 Anagram Therapeutics, Inc. Methods and compositions for treating congenital sucrase-isomaltase deficiency

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110111413A1 (en) 2001-02-02 2011-05-12 Padgett Hal S Method of optimizing codon usage through dna shuffling
US20080292918A1 (en) 2007-05-25 2008-11-27 Caine Finnerty Electrochemical system having multiple independent circuits
MX2009012850A (es) 2007-06-01 2010-02-15 Solazyme Inc Produccion de aceite en microorganismos.
WO2009100231A2 (en) 2008-02-06 2009-08-13 The Regents Of The University Of California Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi
US7632995B2 (en) 2008-05-09 2009-12-15 Monsanto Technology Llc Plants and seeds of hybrid corn variety CH852179
US7935515B2 (en) 2008-11-28 2011-05-03 Solazyme, Inc. Recombinant microalgae cells producing novel oils
US20100297749A1 (en) 2009-04-21 2010-11-25 Sapphire Energy, Inc. Methods and systems for biofuel production
SG179157A1 (en) 2009-09-15 2012-05-30 Sapphire Energy Inc A system for transformation of the chloroplast genome of scenedesmus sp. and dunaliella sp.
ES2718489T3 (es) 2010-05-28 2019-07-02 Corbion Biotech Inc Método para producir aceites a partir de Prototheca
AU2012253803A1 (en) 2011-05-06 2013-12-05 Terravia Holdings, Inc. Genetically engineered microorganisms that metabolize xylose
WO2013082186A2 (en) 2011-11-28 2013-06-06 Solazyme, Inc. Genetically engineered microbial strains including prototheca lipid pathway genes
SG11201406711TA (en) 2012-04-18 2014-11-27 Solazyme Inc Tailored oils
RS59199B1 (sr) 2012-05-25 2019-10-31 Univ California Metode i jedinjenja za rnk-upravljanu ciljanu dnk modifikaciju i za rnk- upravljanu modulaciju transkripta
CN104968788A (zh) 2012-12-07 2015-10-07 索拉兹米公司 包括原始小球藻脂质途径基因的基因工程化微生物菌株
US9260752B1 (en) 2013-03-14 2016-02-16 Caribou Biosciences, Inc. Compositions and methods of nucleic acid-targeting nucleic acids
KR101520614B1 (ko) 2013-07-25 2015-05-19 서울대학교산학협력단 당단백질의 탈당화 검출을 통한 암 진단 방법
EP3052636A2 (en) 2013-10-04 2016-08-10 Solazyme, Inc. Tailored oils
US9969990B2 (en) 2014-07-10 2018-05-15 Corbion Biotech, Inc. Ketoacyl ACP synthase genes and uses thereof
EP3194582A2 (en) 2014-09-18 2017-07-26 TerraVia Holdings, Inc. Acyl-acp thioesterases and mutants thereof
US20180142218A1 (en) 2016-10-05 2018-05-24 Terravia Holdings, Inc. Novel acyltransferases, variant thioesterases, and uses thereof
CN110078832B (zh) * 2019-04-18 2021-12-14 江南大学 一类基于ZZ domain的二抗及其制备方法和应用

Also Published As

Publication number Publication date
US20230037413A1 (en) 2023-02-09
EP4061936A1 (en) 2022-09-28
US12338468B2 (en) 2025-06-24
WO2021102139A1 (en) 2021-05-27

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