BR102015002008A2 - cateter - Google Patents
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- BR102015002008A2 BR102015002008A2 BR102015002008A BR102015002008A BR102015002008A2 BR 102015002008 A2 BR102015002008 A2 BR 102015002008A2 BR 102015002008 A BR102015002008 A BR 102015002008A BR 102015002008 A BR102015002008 A BR 102015002008A BR 102015002008 A2 BR102015002008 A2 BR 102015002008A2
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- BR
- Brazil
- Prior art keywords
- catheter
- present
- presented
- hypothermia
- cooling
- Prior art date
Links
- 238000001816 cooling Methods 0.000 abstract description 11
- 210000004556 brain Anatomy 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract description 2
- 230000002631 hypothermal effect Effects 0.000 description 10
- 238000001802 infusion Methods 0.000 description 8
- 208000029028 brain injury Diseases 0.000 description 7
- 230000006698 induction Effects 0.000 description 4
- 230000006931 brain damage Effects 0.000 description 2
- 231100000874 brain damage Toxicity 0.000 description 2
- 238000007912 intraperitoneal administration Methods 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 230000004224 protection Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 206010007617 Cardio-respiratory arrest Diseases 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 208000010496 Heart Arrest Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 208000030886 Traumatic Brain injury Diseases 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 230000002802 cardiorespiratory effect Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 230000001149 cognitive effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000006266 hibernation Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000001989 nasopharynx Anatomy 0.000 description 1
- 230000004112 neuroprotection Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000009529 traumatic brain injury Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F7/123—Devices for heating or cooling internal body cavities using a flexible balloon containing the thermal element
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/0085—Devices for generating hot or cold treatment fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0001—Body part
- A61F2007/0002—Head or parts thereof
- A61F2007/0006—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
- A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
- A61F2007/0069—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit with return means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0091—Heating or cooling appliances for medical or therapeutic treatment of the human body inflatable
- A61F2007/0092—Heating or cooling appliances for medical or therapeutic treatment of the human body inflatable with, or also with, a substance other than air
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
cateter a presente invenção descreve um cateter de resfriamento encefálico por via nasofaríngea. a presente invenção situa-se nos campos da medicina e da engenharia
Description
Relatório Descritivo de Patente de Invenção Cateter Campo da Invenção [0001] O presente relatório contempla conhecimentos, informações e/ou dados confidenciais utilizáveis na indústria, comércio ou prestação de serviços, para os quais o detentor requer: a proteção estabelecida no inciso XXIX do Art. 5o da Constituição Federal; a manutenção do status jurídico de confidencialidade/segredo; a manutenção do status físico de confidencialidade/segredo pelo tempo previsto na Lei 9.279/96, Lei da Propriedade Industrial; e os direitos previstos no Art. 195 da Lei 9.279/96. A criação industrial ora descrita compreende uma invenção passível de proteção patentária. A presente invenção descreve um cateter de resfriamento encefálico por via nasofaríngea. A presente invenção situa-se nos campos da Medicina e da Engenharia.
Antecedentes da Invenção [0002] Lesões cerebrais são causas de graves sequelas motoras e/ou cognitivas para o indivíduo e muitas vezes levam o indivíduo à morte. As lesões cerebrais iniciais podem ser agravadas nas primeiras 120 horas, principalmente no intervalo das primeiras 48 horas.
[0003] Para que se impeça a progressão das lesões cerebrais, pode-se induzir o indivíduo à hípotermia, desse modo diminuindo o metabolismo das células (hibernação) e permitir que ocorra recuperação celular.
[0004] São várias as condições possíveis para que haja hípotermia: paradas cardiorrespiratórias, acidentes vasculares cerebrais (AVCs) e traumas crânioencefálicos (TCEs).
[0005] Na busca pelo estado da técnica em literaturas científica e patentária, foram encontrados os seguintes documentos que tratam sobre o tema: [0006] O documento Hipotermia terapêutica pós-reanimação cardiorrespiratória; evidências e aspectos práticos. Rev. bras. ter. intensiva vol.21 no.1 São Paulo Jan./Mar. 2009 revela algumas possibilidades de tratamento da hipotermia, mas não revela nem sequer sugere o cateter revelado pela presente invenção. É de se ressaltar que o cateter descrito pela presente invenção permite a hipotermia apenas das regiões cerebrais em que há necessidade de haver hipotermia.
[0007] Assim, do que se depreende da literatura pesquisada, não foram encontrados documentos antecipando ou sugerindo os ensinamentos da presente invenção, de forma que a solução aqui proposta possui novidade e atividade inventiva frente ao estado da técnica.
[0008] Dessa forma, a presente invenção apresenta uma solução para o problema da indução de hipotermia nos casos de lesões cerebrais, descrevendo-se na presente invenção um cateter que resolve o problema de indução de hipotermia nos casos de lesões cerebrais.
Sumário da Invenção [0009] Dessa forma, a presente invenção tem por objetivo resolver os problemas constantes no estado da técnica a partir de um cateter que resolve o problema da indução de hipotermia em pacientes com lesões cerebrais.
[0010] É um objeto da presente invenção um cateter conforme definido e revelado pelas figuras 1 a 9 do presente pedido de patente.
[0011] É um outro objeto da presente invenção um cateter substancialmente conforme as figuras 1 a 9 do presente pedido de patente.
[0012] Ainda, o conceito inventivo comum a todos os contextos de proteção reivindicados refere-se ao cateter que é descritivo pela presente invenção.
[0013] Estes e outros objetos da invenção serão imediatamente valorizados pelos versados na arte e pelas empresas com interesses no segmento, e serão descritos em detalhes suficientes para sua reprodução na descrição a seguir.
Breve Descrição das Figuras [0014] Com o intuito de melhor definir e esclarecer o conteúdo do presente pedido de patente, são apresentadas as presente figuras: [0015] A figura 1 mostra a concretização do cateter apresentado pela presente invenção, cateter este apresentando bolsa de refrigeração (1), haste de infusão (2), tubo flexível (3 e 4), ponta da haste de infusão (5) e conexão festo (6).
[0016] A figura 2 mostra a concretização do cateter apresentado pela presente invenção, cateter este apresentando conexão de entrada do ar (1), bolsa de refrigeração (2), conexão de entrada do ar (3), haste de infusão (4), ponta da haste de infusão (5), tubo flexível (6 e 8), tubo com um canal intraparede (7) e conexão festo (9).
[0017] A figura 3 mostra a concretização do cateter apresentado pela presente invenção, cateter este apresentando conjunto bolsa de ar (1), bolsa de refrigeração (2), conexão de entrada do ar (3), conexão da seringa (4), haste de infusão (5), ponta da haste de infusão (6), tubo flexível (7 e 10), tubo com um canal intraparede (8) e conexão festo (9).
[0018] A figura 4 mostra a concretização do cateter apresentado pela presente invenção.
[0019] A figura 5 mostra a concretização do cateter apresentado pela presente invenção.
[0020] A figura 6 mostra a concretização do cateter apresentado pela presente invenção.
[0021] A figura 7 mostra a concretização do cateter apresentado pela presente invenção, apresentando porção meleável do cateter - poliuretano maleável (1), fio guia - metálico (2), porção rígida do cateter - poliuretano pouco maleável (3), conector macho tipo luer-lock para conexão com sistema de resfriamento (4) [0022] A figura 8 mostra a concretização do cateter apresentado pela presente invenção, apresentando bolsa (01), fio de infusão (2), tubo (3), tubo para inflar o balão com conexão (4), bolsa de ar (05) e conexão festo (06).
[0023] A figura 9 mostra a concretização do cateter apresentado pela presente invenção, apresentando bolsa de refrigeração (1), fio de infusão (02), tubo (03), tampa do tubo de injeção do gel (04), bolsa de ar (5), tubo para inflar o balão com conexão (06) e conexão festo (07).
Descrição Detalhada da Invenção [0024] É um objeto da presente invenção um cateter conforme definido e revelado pelas figuras 1 a 9 do presente pedido de patente.
[0025] É um outro objeto da presente invenção um cateter substancialmente conforme as figuras 1 a 9 do presente pedido de patente.
[0026] São várias as vantagens da presente invenção: a via nasofaríngea é de fácil acesso, pode-se realizar a indução hipotérmica rapidamente e nas áreas desejadas, dentre outras vantagens técnicas e econômicas.
Exemplo 1. Exemplo de concretização da invenção [0027] Os exemplos aqui mostrados têm o intuito somente de exemplificar uma das inúmeras maneiras de se realizar a invenção, contudo sem limitar, o escopo da mesma.
Exemplo I - Exemplos de concretização da invenção [0028] Os exemplos de cateter estão indicados nas figuras 1 a 9 do presente pedido de patente e incluem também alternativas e variantes dos referidos cateteres.
[0029] Outro exemplo de concretização da invenção está indicado a seguir: [0030] Dimensões aproximadas do cateter nasofaríngeo em sua apresentação final: [0031] Dimensões : 340 mm de comprimento [0032] Diâmetro interno : 6 mm [0033] Diâmetro externo: 8,5 mm [0034] Peso aproximado: 50 g [0035] ESTERILIZAÇÃO: o cateter é esterilizado por oxido de etileno.
[0036] RE-ESTERILIZAÇÃO: este produto é recomendado para ser utilizado uma única vez.
[0037] Descrição do Produto: [0038] O cateter de resfriamento nasofaríngeo é usado para diminuir a temperatura do tecido encefálico adjacente à nasofaringe. Os componentes do sistema facilitam o posicionamento do cateter. No interior do cateter haverá circulação contínua de líquido resfriado por um sistema externo conectado ao mesmo.
[0039] O cateter de resfriamento nasofaríngeo pode ser utilizado para pacientes com lesões cerebrais graves que tenham indicação de resfriamento cerebral como método de neuroproteção e não existem contra-indicações conhecidas ao uso do cateter de resfriamento nasofaríngeo.
[0040] Os versados na arte valorizarão os conhecimentos aqui apresentados e poderão reproduzir a invenção nas modalidades apresentadas e em outras variantes, abrangidas no escopo das reivindicações anexas.
Reivindicações Cateter
Claims (1)
1. Cateter caracterizado por ser conforme definido pelas figuras 1 a 9.
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR102015002008A BR102015002008A2 (pt) | 2015-01-28 | 2015-01-28 | cateter |
| EP16742597.4A EP3250282A4 (en) | 2015-01-28 | 2016-01-27 | Catheter, system for target temperature management and method for target body temperature management |
| JP2017540776A JP2018505732A (ja) | 2015-01-28 | 2016-01-27 | 標的温度管理のためのカテーテル、システム、および標的体温管理のための方法 |
| PCT/BR2016/050014 WO2016119033A2 (en) | 2015-01-28 | 2016-01-27 | Catheter, system for target temperature management and method for target body temperature management |
| BR112017016245-8A BR112017016245B1 (pt) | 2015-01-28 | 2016-01-27 | Cateter e sistema para administração de temperatura alvo |
| US15/546,161 US20180014970A1 (en) | 2015-01-28 | 2016-01-27 | Catheter, system for target temperature management and method for target body temperature management |
| CN201680019004.1A CN107847346A (zh) | 2015-01-28 | 2016-01-27 | 目标温度管理的导管、系统和目标身体温度管理的方法 |
| JP2021066601A JP2021102134A (ja) | 2015-01-28 | 2021-04-09 | 標的温度管理のためのカテーテル、システム、および標的体温管理のための方法 |
| US17/370,089 US20210361476A1 (en) | 2015-01-28 | 2021-07-08 | Catheter, System for Target Temperature Management and Method for Target Body Temperature Management |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR102015002008A BR102015002008A2 (pt) | 2015-01-28 | 2015-01-28 | cateter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR102015002008A2 true BR102015002008A2 (pt) | 2016-08-23 |
Family
ID=56544485
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR102015002008A BR102015002008A2 (pt) | 2015-01-28 | 2015-01-28 | cateter |
| BR112017016245-8A BR112017016245B1 (pt) | 2015-01-28 | 2016-01-27 | Cateter e sistema para administração de temperatura alvo |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017016245-8A BR112017016245B1 (pt) | 2015-01-28 | 2016-01-27 | Cateter e sistema para administração de temperatura alvo |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20180014970A1 (pt) |
| EP (1) | EP3250282A4 (pt) |
| JP (2) | JP2018505732A (pt) |
| CN (1) | CN107847346A (pt) |
| BR (2) | BR102015002008A2 (pt) |
| WO (1) | WO2016119033A2 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11797641B2 (en) | 2015-02-03 | 2023-10-24 | 1Qb Information Technologies Inc. | Method and system for solving the lagrangian dual of a constrained binary quadratic programming problem using a quantum annealer |
| CA2881033C (en) | 2015-02-03 | 2016-03-15 | 1Qb Information Technologies Inc. | Method and system for solving lagrangian dual of a constrained binary quadratic programming problem |
| EP4036708A1 (en) | 2016-03-11 | 2022-08-03 | 1QB Information Technologies Inc. | Methods and systems for quantum computing |
| WO2017201625A1 (en) | 2016-05-25 | 2017-11-30 | Samuel Victor Lichtenstein | System for treating unwanted tissue |
| US10044638B2 (en) | 2016-05-26 | 2018-08-07 | 1Qb Information Technologies Inc. | Methods and systems for quantum computing |
| US9870273B2 (en) | 2016-06-13 | 2018-01-16 | 1Qb Information Technologies Inc. | Methods and systems for quantum ready and quantum enabled computations |
| WO2019104443A1 (en) | 2017-12-01 | 2019-06-06 | 1Qb Information Technologies Inc. | Systems and methods for stochastic optimization of a robust inference problem |
| JP7713882B2 (ja) | 2018-12-06 | 2025-07-28 | ワンキュービー インフォメーション テクノロジーズ インク． | 人工知能駆動型量子計算 |
| WO2020255076A1 (en) | 2019-06-19 | 2020-12-24 | 1Qb Information Technologies Inc. | Method and system for mapping a dataset from a hilbert space of a given dimension to a hilbert space of a different dimension |
| EP4070205A4 (en) | 2019-12-03 | 2024-05-01 | 1QB Information Technologies Inc. | SYSTEM AND METHOD FOR ENABLING ACCESS TO A PHYSICS-INSPIRED COMPUTER AND A PHYSICS-INSPIRED COMPUTER SIMULATOR |
| WO2021237350A1 (en) | 2020-05-27 | 2021-12-02 | 1Qb Information Technologies Inc. | Methods and systems for solving an optimization problem using a flexible modular approach |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6325818B1 (en) * | 1999-10-07 | 2001-12-04 | Innercool Therapies, Inc. | Inflatable cooling apparatus for selective organ hypothermia |
| US6261312B1 (en) * | 1998-06-23 | 2001-07-17 | Innercool Therapies, Inc. | Inflatable catheter for selective organ heating and cooling and method of using the same |
| US6368304B1 (en) * | 1999-02-19 | 2002-04-09 | Alsius Corporation | Central venous catheter with heat exchange membrane |
| JP2000245764A (ja) * | 1999-02-26 | 2000-09-12 | Kanji Yoshida | 視床系冷却装置及び冷却体の使用方法 |
| US6436071B1 (en) * | 1999-06-08 | 2002-08-20 | The Trustees Of Columbia University In The City Of New York | Intravascular systems for corporeal cooling |
| CA2760543C (en) * | 2002-09-12 | 2013-08-13 | Zoll Circulation, Inc. | System and method for determining and controlling core body temperature |
| US7758623B2 (en) * | 2003-03-17 | 2010-07-20 | The Board Of Trustees Of The Leland Stanford Junior University | Transesophageal heat exchange catheter for cooling of the heart |
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-
2015
- 2015-01-28 BR BR102015002008A patent/BR102015002008A2/pt not_active IP Right Cessation
-
2016
- 2016-01-27 EP EP16742597.4A patent/EP3250282A4/en not_active Ceased
- 2016-01-27 WO PCT/BR2016/050014 patent/WO2016119033A2/en not_active Ceased
- 2016-01-27 CN CN201680019004.1A patent/CN107847346A/zh active Pending
- 2016-01-27 JP JP2017540776A patent/JP2018505732A/ja active Pending
- 2016-01-27 US US15/546,161 patent/US20180014970A1/en not_active Abandoned
- 2016-01-27 BR BR112017016245-8A patent/BR112017016245B1/pt active IP Right Grant
-
2021
- 2021-04-09 JP JP2021066601A patent/JP2021102134A/ja active Pending
- 2021-07-08 US US17/370,089 patent/US20210361476A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3250282A2 (en) | 2017-12-06 |
| WO2016119033A2 (en) | 2016-08-04 |
| BR112017016245B1 (pt) | 2022-06-28 |
| WO2016119033A3 (en) | 2017-11-09 |
| JP2021102134A (ja) | 2021-07-15 |
| EP3250282A4 (en) | 2018-12-05 |
| US20180014970A1 (en) | 2018-01-18 |
| CN107847346A (zh) | 2018-03-27 |
| US20210361476A1 (en) | 2021-11-25 |
| JP2018505732A (ja) | 2018-03-01 |
| BR112017016245A2 (pt) | 2018-03-27 |
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