BR0316464A - Métodos para preparar e purificar um composto - Google Patents
Métodos para preparar e purificar um compostoInfo
- Publication number
- BR0316464A BR0316464A BR0316464-0A BR0316464A BR0316464A BR 0316464 A BR0316464 A BR 0316464A BR 0316464 A BR0316464 A BR 0316464A BR 0316464 A BR0316464 A BR 0316464A
- Authority
- BR
- Brazil
- Prior art keywords
- preparing
- purifying
- compound
- methods
- directed
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 229940082638 cardiac stimulant phosphodiesterase inhibitors Drugs 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 abstract 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"MéTODOS PARA PREPARAR E PURIFICAR UM COMPOSTO". Em um aspecto, a presente invenção é direcionada a um método de pote de preparar intermediários de Fórmula (V), que sejam úteis em produzir inibidores de fosfodiesterase-4. A presente invenção é também direcionada a um método para preparar inibidores de fosfodiesterase que compreendem as Fórmulas (IX, IXa).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42831502P | 2002-11-22 | 2002-11-22 | |
| US47265503P | 2003-05-22 | 2003-05-22 | |
| PCT/US2003/036806 WO2004048377A2 (en) | 2002-11-22 | 2003-11-18 | Method of preparing inhibitors of phosphodiesterase-4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0316464A true BR0316464A (pt) | 2005-10-11 |
Family
ID=32397111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0316464-0A BR0316464A (pt) | 2002-11-22 | 2003-11-18 | Métodos para preparar e purificar um composto |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7312334B2 (pt) |
| EP (1) | EP1565466A2 (pt) |
| JP (1) | JP2006513271A (pt) |
| KR (1) | KR20050085107A (pt) |
| AR (1) | AR042194A1 (pt) |
| AU (1) | AU2003291050A1 (pt) |
| BR (1) | BR0316464A (pt) |
| CA (1) | CA2506656A1 (pt) |
| HR (1) | HRP20050450A2 (pt) |
| MX (1) | MXPA05005405A (pt) |
| NZ (1) | NZ539646A (pt) |
| PL (1) | PL376796A1 (pt) |
| RU (1) | RU2323938C2 (pt) |
| WO (1) | WO2004048377A2 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005105084A1 (en) | 2004-04-26 | 2005-11-10 | Merck Frosst Canada Ltd. | Alternative forms of the phosphodiesterase-4 inhibitor n-cyclopropyl-1-{3-[(1-oxidopryidin-3-yl)ethynyl]phenyl}-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxyamide |
| WO2008026687A1 (en) | 2006-09-01 | 2008-03-06 | Kyorin Pharmaceutical Co., Ltd. | Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor comprising the derivative |
| JP2010523695A (ja) * | 2007-04-11 | 2010-07-15 | アルコン リサーチ， リミテッド | アレルギー性鼻炎およびアレルギー性結膜炎を処置するためのＴＮＦαのインヒビターおよび抗ヒスタミン薬の使用 |
| CA2773483A1 (en) * | 2009-10-01 | 2011-04-07 | Alcon Research, Ltd. | Olopatadine compositions and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE757508A (fr) | 1969-10-15 | 1971-04-14 | Rieter Ag Maschf | Procede pour la production d'un faisceau de fibres continu regulier et dispositif pour l'execution du procede |
| AR208414A1 (es) * | 1974-11-07 | 1976-12-27 | Rhone Poulenc Ind | Procedimiento para obtener nuevos derivados de la((acil-4piperazinil-1)carboniloxi-5 pirrolinona-2) |
| ES2247325T3 (es) * | 2001-05-24 | 2006-03-01 | MERCK FROSST CANADA & CO. | Inhibidores de 1-biaril-1,8-naftiridin-4-ona fosfodiesterasa-4. |
| JO2311B1 (en) * | 2001-08-29 | 2005-09-12 | ميرك فروست كندا ليمتد | Alkyl inhibitors Ariel phosphodiesterase-4 |
-
2003
- 2003-11-17 AR ARP030104228A patent/AR042194A1/es not_active Application Discontinuation
- 2003-11-18 WO PCT/US2003/036806 patent/WO2004048377A2/en not_active Ceased
- 2003-11-18 NZ NZ539646A patent/NZ539646A/en unknown
- 2003-11-18 PL PL376796A patent/PL376796A1/pl not_active Application Discontinuation
- 2003-11-18 HR HR20050450A patent/HRP20050450A2/xx not_active Application Discontinuation
- 2003-11-18 CA CA002506656A patent/CA2506656A1/en not_active Abandoned
- 2003-11-18 JP JP2005510366A patent/JP2006513271A/ja not_active Withdrawn
- 2003-11-18 US US10/530,465 patent/US7312334B2/en not_active Expired - Fee Related
- 2003-11-18 AU AU2003291050A patent/AU2003291050A1/en not_active Abandoned
- 2003-11-18 KR KR1020057009225A patent/KR20050085107A/ko not_active Withdrawn
- 2003-11-18 EP EP03783636A patent/EP1565466A2/en not_active Withdrawn
- 2003-11-18 BR BR0316464-0A patent/BR0316464A/pt not_active IP Right Cessation
- 2003-11-18 RU RU2005119645/04A patent/RU2323938C2/ru not_active IP Right Cessation
- 2003-11-18 MX MXPA05005405A patent/MXPA05005405A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003291050A1 (en) | 2004-06-18 |
| EP1565466A2 (en) | 2005-08-24 |
| NZ539646A (en) | 2008-03-28 |
| KR20050085107A (ko) | 2005-08-29 |
| US7312334B2 (en) | 2007-12-25 |
| HRP20050450A2 (en) | 2006-02-28 |
| PL376796A1 (pl) | 2006-01-09 |
| WO2004048377A2 (en) | 2004-06-10 |
| RU2323938C2 (ru) | 2008-05-10 |
| US20060019981A1 (en) | 2006-01-26 |
| WO2004048377A3 (en) | 2004-09-02 |
| RU2005119645A (ru) | 2006-01-20 |
| MXPA05005405A (es) | 2005-08-03 |
| AR042194A1 (es) | 2005-06-15 |
| CA2506656A1 (en) | 2004-06-10 |
| JP2006513271A (ja) | 2006-04-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: PARA INT.CL: C07D 471/04, A61P 11/00, A61P 29/00 Ipc: C07D 471/04 (2011.01) |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |