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BR0315681A - Composto e seus sais e hidratos farmaceuticamente aceitáveis, composição farmacêutica, métodos para o tratamento de doenças mediadas pela prostaglandina d2, para o tratamento de congestão nasal, para o tratamento de asma alérgica, e para o tratamento de rinite alérgica, composto ou um seu sal ou solvato farmaceuticamente aceitável, sal ou hidrato do composto, e, uso de um composto ou de um seu sal ou solvato farmaceuticamente aceitável - Google Patents

Composto e seus sais e hidratos farmaceuticamente aceitáveis, composição farmacêutica, métodos para o tratamento de doenças mediadas pela prostaglandina d2, para o tratamento de congestão nasal, para o tratamento de asma alérgica, e para o tratamento de rinite alérgica, composto ou um seu sal ou solvato farmaceuticamente aceitável, sal ou hidrato do composto, e, uso de um composto ou de um seu sal ou solvato farmaceuticamente aceitável

Info

Publication number
BR0315681A
BR0315681A BR0315681-8A BR0315681A BR0315681A BR 0315681 A BR0315681 A BR 0315681A BR 0315681 A BR0315681 A BR 0315681A BR 0315681 A BR0315681 A BR 0315681A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutically acceptable
salt
treating
solvate
Prior art date
Application number
BR0315681-8A
Other languages
English (en)
Inventor
Yves Leblanc
Claude Dufresne
Patrick Roy
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Publication of BR0315681A publication Critical patent/BR0315681A/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
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  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)

Abstract

"COMPOSTO E SEUS SAIS E HIDRATOS FARMACEUTICAMENTE ACEITáVEIS, COMPOSIçãO FARMACêUTICA, MéTODOS PARA O TRATAMENTO DE DOENçAS MEDIADAS PELA PROSTAGLANDINA D2, PARA O TRATAMENTO DE CONGESTãO NASAL, PARA O TRATAMENTO DE ASMA ALéRGICA E PARA O TRATAMENTO DE RINITE ALéRGICA COMPOSTO OU UM SEU SAL OU SOLVATO FARMACEUTICAMENTE ACEITáVEL, SAL OU HIDRATO DO COMPOSTO, E, USO DE UM COMPOSTO OU DE UM SEU SAL OU SOLVATO FARMACEUTICAMENTE ACEITáVEL". Os derivados de piridopirrolizina e de piridoindolizina são antagonistas do receptor da prostaglandina úteis para o tratamento de doenças mediadas pela prostaglandina, tais como as rinites alérgicas, a congestão nasal e a asma.
BR0315681-8A 2002-10-30 2003-10-28 Composto e seus sais e hidratos farmaceuticamente aceitáveis, composição farmacêutica, métodos para o tratamento de doenças mediadas pela prostaglandina d2, para o tratamento de congestão nasal, para o tratamento de asma alérgica, e para o tratamento de rinite alérgica, composto ou um seu sal ou solvato farmaceuticamente aceitável, sal ou hidrato do composto, e, uso de um composto ou de um seu sal ou solvato farmaceuticamente aceitável BR0315681A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42244302P 2002-10-30 2002-10-30
US48262603P 2003-06-26 2003-06-26
PCT/CA2003/001658 WO2004039807A1 (en) 2002-10-30 2003-10-28 Pyridopyrrolizine and pyridoindolizine derivatives

Publications (1)

Publication Number Publication Date
BR0315681A true BR0315681A (pt) 2005-09-06

Family

ID=32233493

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0315681-8A BR0315681A (pt) 2002-10-30 2003-10-28 Composto e seus sais e hidratos farmaceuticamente aceitáveis, composição farmacêutica, métodos para o tratamento de doenças mediadas pela prostaglandina d2, para o tratamento de congestão nasal, para o tratamento de asma alérgica, e para o tratamento de rinite alérgica, composto ou um seu sal ou solvato farmaceuticamente aceitável, sal ou hidrato do composto, e, uso de um composto ou de um seu sal ou solvato farmaceuticamente aceitável

Country Status (15)

Country Link
US (1) US7618979B2 (pt)
EP (1) EP1558614B1 (pt)
JP (1) JP4332151B2 (pt)
KR (1) KR20050084890A (pt)
AT (1) ATE479686T1 (pt)
AU (1) AU2003275868B2 (pt)
BR (1) BR0315681A (pt)
CA (1) CA2503767C (pt)
DE (1) DE60334015D1 (pt)
MX (1) MXPA05004715A (pt)
NO (1) NO20052591L (pt)
NZ (1) NZ539406A (pt)
PL (1) PL376440A1 (pt)
RU (1) RU2342386C2 (pt)
WO (1) WO2004039807A1 (pt)

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