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BR0313162A - Composto, processo para preparar o mesmo, e, composição farmacêutica - Google Patents

Composto, processo para preparar o mesmo, e, composição farmacêutica

Info

Publication number
BR0313162A
BR0313162A BR0313162-9A BR0313162A BR0313162A BR 0313162 A BR0313162 A BR 0313162A BR 0313162 A BR0313162 A BR 0313162A BR 0313162 A BR0313162 A BR 0313162A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
preparing same
antiinflammatory activity
macrolide
Prior art date
Application number
BR0313162-9A
Other languages
English (en)
Inventor
Mauro Napoletano
Ermanno Moriggi
Andrea Mereu
Fernando Ornaghi
Gabriele Morazzoni
Roberto Longoni
Carlo Riva
Luciano Pacchetti
Franco Pellacini
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of BR0313162A publication Critical patent/BR0313162A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSTO, PROCESSO PARA PREPARAR O MESMO, E, COMPOSIçãO FARMACêUTICA" . Descreve-se compostos macrolídios dotados de atividade antiinflamatória, e, mais particularmente, derivados de macrolídios não apresentando cladinose na posição 3, com atividade antiinflamatória, sais farmaceuticamente aceitáveis dos mesmos e composições farmacêuticas contendo os mesmos como ingrediente ativo.
BR0313162-9A 2002-08-01 2003-07-29 Composto, processo para preparar o mesmo, e, composição farmacêutica BR0313162A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001726A ITMI20021726A1 (it) 2002-08-01 2002-08-01 Macrolidi ad attivita' antiinfiammatoria.
PCT/EP2003/008448 WO2004013153A2 (en) 2002-08-01 2003-07-29 Macrolide compounds endowed with antiinflammatory activity

Publications (1)

Publication Number Publication Date
BR0313162A true BR0313162A (pt) 2005-07-05

Family

ID=31198615

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0313162-9A BR0313162A (pt) 2002-08-01 2003-07-29 Composto, processo para preparar o mesmo, e, composição farmacêutica

Country Status (18)

Country Link
US (2) US7488811B2 (pt)
EP (2) EP1529053B1 (pt)
JP (1) JP4589110B2 (pt)
KR (1) KR101051369B1 (pt)
CN (1) CN100335491C (pt)
AT (1) ATE509938T1 (pt)
AU (1) AU2003269861B2 (pt)
BR (1) BR0313162A (pt)
CA (1) CA2493995C (pt)
CO (1) CO5720000A2 (pt)
ES (1) ES2364647T3 (pt)
HR (1) HRP20050195B1 (pt)
IL (1) IL166527A0 (pt)
IT (1) ITMI20021726A1 (pt)
NZ (1) NZ537992A (pt)
PT (1) PT1529053E (pt)
RU (1) RU2330856C2 (pt)
WO (1) WO2004013153A2 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
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ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ES2316805T3 (es) 2002-08-29 2009-04-16 Pfizer Inc. Compuestos motilidos.
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
US7407941B2 (en) 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
ITMI20040124A1 (it) * 2004-01-29 2004-04-29 Zambon Spa Macrolidi ad attivita' antiinfiammatoria
EP2716647A3 (en) * 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
CN1950388A (zh) * 2004-02-27 2007-04-18 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
DE602006004555D1 (de) * 2005-01-13 2009-02-12 Glaxosmithkline Zagreb Decladinosyl-macrolide mit entzündungshemmender wirkung
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
EP1907406B1 (en) * 2005-07-06 2010-04-28 ZAMBON S.p.A. Crystalline forms of macrolide compounds endowed with antiinflammatory activity
US8278281B2 (en) 2005-08-24 2012-10-02 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
WO2007025089A2 (en) 2005-08-24 2007-03-01 Rib-X Pharmaceutical, Inc. Triazole compounds and methods of making and using the same
WO2007047863A2 (en) 2005-10-19 2007-04-26 Teva Pharmaceutical Industries, Ltd. Crystals of laquinimod sodium, and process for the manufacture thereof
CA2632779A1 (en) * 2005-12-08 2007-06-14 Pfizer Inc. Method for demethylating the 3'-dimethylamino group of erythromycin compounds
RU2455308C2 (ru) 2006-05-01 2012-07-10 Тайсо Фармасьютикал Ко., Лтд. Макролидные производные
WO2008143729A2 (en) * 2007-02-28 2008-11-27 Rib-X Pharmaceuticals, Inc. Macrolide compounds and methods of making and using the same
KR101617897B1 (ko) 2008-02-08 2016-05-03 바실리어 파마슈티카 아게 신규 마크로라이드 및 그의 용도
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides
BRPI1006114A2 (pt) 2009-01-30 2018-02-06 Glaxo Group Ltd "macrolídeo antiinflamatório".
JP2012516305A (ja) 2009-01-30 2012-07-19 グラクソ グループ リミテッド 好中球優位の炎症性疾患の治療のための９−デオキソ−９ａ−メチル−９ａ−アザ−９ａ−ホモエリスロマイシンａ誘導体
ES2582794T3 (es) 2009-08-13 2016-09-15 Basilea Pharmaceutica Ag Nuevos macrólidos y su uso
WO2011131749A1 (en) 2010-04-23 2011-10-27 Glaxo Group Limited New 14 and 15 membered macrolides for the treatment of neutrophil dominated inflammatory diseases
KR20150091077A (ko) 2012-11-07 2015-08-07 테바 파마슈티컬 인더스트리즈 리미티드 라퀴니모드의 아민염
EP2970129A2 (en) 2013-03-14 2016-01-20 Teva Pharmaceutical Industries Ltd. Crystals of laquinimod sodium and improved process for the manufacture thereof
EP2984087A1 (en) * 2013-04-10 2016-02-17 Probiotic Pharmaceuticals APS Azithromycin antimicrobial derivatives with non-antibiotic pharmaceutical effect
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
EP4051687A4 (en) * 2020-01-08 2022-12-21 Beijing Continent Pharmaceuticals Co., Ltd. MACROLIDE COMPOUND AND USE THEREOF FOR THE TREATMENT OF CHRONIC RESPIRATORY DISEASE

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GB1100504A (en) 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US3623784A (en) * 1969-11-05 1971-11-30 Massey Ferguson Ind Ltd Cabinet joint structure
US3725385A (en) 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US3923784A (en) 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
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EP0254534A3 (en) 1986-07-24 1991-04-17 William S. Robinson Erythromycin derivatives and compositions and use for inhibiting virus replication and disease
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
WO1992016226A1 (en) 1991-03-19 1992-10-01 Smithkline Beecham Corporation Il-1 inhibitors
CA2154550A1 (en) * 1993-01-26 1994-08-04 Yoko Misawa 5-o-desosaminylerythronolide derivatives
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CA2196879A1 (en) 1994-08-12 1996-02-22 Akihiko Hoshino Interleukin-5 production inhibitor
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FR2735694B1 (fr) * 1995-06-20 1997-08-08 Roussel Uclaf Le cladinose a titre de medicament et les compositions pharmaceutiques les renfermant
FR2738571B1 (fr) * 1995-09-11 1997-10-17 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
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FR2745290B1 (fr) * 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
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JPH11236395A (ja) * 1997-12-11 1999-08-31 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
US5892008A (en) * 1997-12-16 1999-04-06 Abbott Laboratories Process for the preparation of 6-O-methyl erythromycin a using 9-hydroxy erythromycin derivatives
PT941998E (pt) 1998-03-03 2004-12-31 Pfizer Prod Inc Antibioticos macrolidos do tipo 3,6-cetal
IT1306205B1 (it) * 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
DE19910159A1 (de) 1999-02-26 2000-09-14 Rosemarie Heis Spezifische lgY-Eidotterantikörper, ihre Gewinnung und ihre Verwendung
JP2000351793A (ja) * 1999-06-09 2000-12-19 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
US6437106B1 (en) * 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
JP2001181294A (ja) * 1999-12-27 2001-07-03 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
US20060043226A1 (en) * 2004-08-24 2006-03-02 Keith Roozeboom Apparatus and method for grinding with staggered cutters
US7096915B2 (en) * 2004-11-05 2006-08-29 Hsiu-Man Yu Chen Tape-roll supporting device

Also Published As

Publication number Publication date
PT1529053E (pt) 2011-07-05
CA2493995C (en) 2011-01-04
EP1529053A2 (en) 2005-05-11
WO2004013153A2 (en) 2004-02-12
AU2003269861B2 (en) 2010-01-21
ES2364647T3 (es) 2011-09-08
CO5720000A2 (es) 2007-01-31
WO2004013153A3 (en) 2004-04-08
US20060058246A1 (en) 2006-03-16
US20090054357A1 (en) 2009-02-26
CA2493995A1 (en) 2004-02-12
RU2005105592A (ru) 2005-08-27
IL166527A0 (en) 2006-01-15
KR20050037567A (ko) 2005-04-22
HRP20050195B1 (hr) 2013-10-25
NZ537992A (en) 2007-11-30
JP2005538998A (ja) 2005-12-22
CN100335491C (zh) 2007-09-05
US7488811B2 (en) 2009-02-10
ATE509938T1 (de) 2011-06-15
KR101051369B1 (ko) 2011-07-22
ITMI20021726A1 (it) 2004-02-02
JP4589110B2 (ja) 2010-12-01
AU2003269861A1 (en) 2004-02-23
EP2258708A1 (en) 2010-12-08
HRP20050195A2 (en) 2005-12-31
EP1529053B1 (en) 2011-05-18
CN1678620A (zh) 2005-10-05
RU2330856C2 (ru) 2008-08-10
US7704960B2 (en) 2010-04-27

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07F Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette]

Free format text: NOTIFICACAO DE NAO ANUENCIA RELACIONADA COM O ART. 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2317 DE 02-06-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.