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BR0214564A - Processos de tratamento de câncer utilizando um inibidor da fpt e agentes antineoplásicos - Google Patents

Processos de tratamento de câncer utilizando um inibidor da fpt e agentes antineoplásicos

Info

Publication number
BR0214564A
BR0214564A BR0214564-2A BR0214564A BR0214564A BR 0214564 A BR0214564 A BR 0214564A BR 0214564 A BR0214564 A BR 0214564A BR 0214564 A BR0214564 A BR 0214564A
Authority
BR
Brazil
Prior art keywords
antineoplastic agents
fpt inhibitor
treatment processes
cancer treatment
medicament
Prior art date
Application number
BR0214564-2A
Other languages
English (en)
Inventor
David L Cutler
Michael L Meyers
Charles Baum
Sara L Zaknoen
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of BR0214564A publication Critical patent/BR0214564A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"PROCESSOS DE TRATAMENTO DE CâNCER UTILIZANDO UM INIBIDOR DA FPT E AGENTES ANTINEOPLáSICOS". A invenção refere-se a um uso de um inibidor da FPT para a produção de um medicamento para o tratamento de câncer. O tratamento compreende a administração de uma quantidade terapeuticamente eficaz do medicamento e de quantidades terapeuticamente eficazes de um ou mais agentes antineoplásicos. Os cânceres tratados incluem o câncer pulmonar de células que não são pequenas, CML, AML, linfoma sem ser de Hodgkin e mieloma múltiplo.
BR0214564-2A 2001-11-30 2002-11-25 Processos de tratamento de câncer utilizando um inibidor da fpt e agentes antineoplásicos BR0214564A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33441101P 2001-11-30 2001-11-30
PCT/US2002/037954 WO2003047697A2 (en) 2001-11-30 2002-11-25 Use of an farsenyl protein tranferase inhibitor in combination with other antineoplastic agents for the manufacture of a medicament against cancer

Publications (1)

Publication Number Publication Date
BR0214564A true BR0214564A (pt) 2004-11-09

Family

ID=23307076

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214564-2A BR0214564A (pt) 2001-11-30 2002-11-25 Processos de tratamento de câncer utilizando um inibidor da fpt e agentes antineoplásicos

Country Status (13)

Country Link
US (2) US20030185831A1 (pt)
EP (1) EP1448268A2 (pt)
JP (1) JP2005511663A (pt)
CN (2) CN101181269A (pt)
AU (1) AU2002352941A1 (pt)
BR (1) BR0214564A (pt)
CA (1) CA2468839A1 (pt)
HU (1) HUP0402401A2 (pt)
MX (1) MXPA04005207A (pt)
NO (1) NO20042730L (pt)
NZ (1) NZ532562A (pt)
WO (1) WO2003047697A2 (pt)
ZA (1) ZA200403737B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0312821A (pt) * 2002-07-24 2005-04-19 Akira Ohtsuru 4-(4-metil-piperazin-1-il-metil)-n-[(4-metil-3-(4-piridin-3-i l)-pirimidin-2-il-amino)-fenil]-benzamida para tratar câncer anaplásico da tireóide
CA2439440A1 (en) * 2002-09-05 2004-03-05 Emory University Treatment of tuberous sclerosis associated neoplasms
JP2007510661A (ja) * 2003-11-06 2007-04-26 シェーリング　コーポレイション 乳癌の治療のための、ファルネシルトランスフェラーゼインヒビターと抗ホルモン剤との組合せ
JP2007525507A (ja) * 2004-02-26 2007-09-06 ザ ペン ステイト リサーチ ファンデーション オピオイド増殖因子レセプターを用いる、新生物の処置のための組み合わせ療法
US20060205810A1 (en) * 2004-11-24 2006-09-14 Schering Corporation Platinum therapeutic combinations
JP2009511450A (ja) * 2005-10-07 2009-03-19 ノバルティス アクチエンゲゼルシャフト ニロチニブとファルネシルトランスフェラーゼ阻害剤の組合せ
MX2009004554A (es) * 2006-10-25 2009-05-11 Schering Corp Metodos discontinuos de tratamiento de cancer.
US20100069411A1 (en) * 2006-11-28 2010-03-18 Smithkline Beecham (Cork) Ltd. Cancer treatment method
WO2022093744A1 (en) * 2020-10-27 2022-05-05 Wisconsin Alumni Research Foundation Modular dendron micelles for combination immunotherapy
WO2024100093A1 (en) 2022-11-09 2024-05-16 Merck Patent Gmbh Toll-like receptor 7 agonists as immune-stimulators to elicit the innate antitumor immunity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874442A (en) * 1995-12-22 1999-02-23 Schering-Plough Corporation Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease
AU756762B2 (en) * 1997-12-22 2003-01-23 Schering Corporation Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases
US6096757A (en) * 1998-12-21 2000-08-01 Schering Corporation Method for treating proliferative diseases
US6316462B1 (en) * 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
JP5491681B2 (ja) * 2000-02-04 2014-05-14 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 乳ガンの治療のためのファルネシルタンパク質トランスフェラーゼ阻害剤
EP1267848B1 (en) * 2000-02-24 2007-10-17 Janssen Pharmaceutica N.V. Dosing regimen comprising a farnesyl protein transferase inhibitor for the treatment of cancer
US20030181473A1 (en) * 2000-02-29 2003-09-25 Palmer Peter Albert Farnesyl protein transferase inhibitor combinations with taxane compounds
JP2003525255A (ja) * 2000-02-29 2003-08-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ファルネシルタンパク質トランスフェラーゼ阻害剤とさらなる抗癌剤との組み合わせ剤
AR033680A1 (es) * 2000-08-30 2004-01-07 Schering Corp Compuestos triciclicos utiles como inhibidores de la farnesil proteino transferasa y su uso para la manufactura de medicamentos como agentes antitumorales
WO2002028381A2 (en) * 2000-10-05 2002-04-11 Daley George Q Methods of inducing cancer cell death and tumor regression

Also Published As

Publication number Publication date
MXPA04005207A (es) 2004-08-19
CA2468839A1 (en) 2003-06-12
NZ532562A (en) 2007-02-23
HUP0402401A2 (hu) 2005-03-29
JP2005511663A (ja) 2005-04-28
CN1617755A (zh) 2005-05-18
WO2003047697A3 (en) 2003-10-30
CN101181269A (zh) 2008-05-21
US20030185831A1 (en) 2003-10-02
EP1448268A2 (en) 2004-08-25
ZA200403737B (en) 2005-05-23
US20060183765A1 (en) 2006-08-17
NO20042730L (no) 2004-06-29
WO2003047697A2 (en) 2003-06-12
AU2002352941A1 (en) 2003-06-17

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE A 8.6 DA RPI 2108 DE 31/05/2011.

B15K Others concerning applications: alteration of classification

Ipc: A61K 31/4545 (2006.01), A61P 35/00 (2006.01)