BR0212895A - Métodos e composições de novos compostos de triazina - Google Patents
Métodos e composições de novos compostos de triazinaInfo
- Publication number
- BR0212895A BR0212895A BR0212895-0A BR0212895A BR0212895A BR 0212895 A BR0212895 A BR 0212895A BR 0212895 A BR0212895 A BR 0212895A BR 0212895 A BR0212895 A BR 0212895A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- present
- compositions
- methods
- cell proliferation
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 150000003918 triazines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 230000004663 cell proliferation Effects 0.000 abstract 3
- 210000000329 smooth muscle myocyte Anatomy 0.000 abstract 3
- 102100036597 Basement membrane-specific heparan sulfate proteoglycan core protein Human genes 0.000 abstract 2
- 230000028709 inflammatory response Effects 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 108090000054 Syndecan-2 Proteins 0.000 abstract 1
- -1 Triazine Compounds Chemical class 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000003511 endothelial effect Effects 0.000 abstract 1
- 108091005996 glycated proteins Proteins 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000004963 pathophysiological condition Effects 0.000 abstract 1
- 108010049224 perlecan Proteins 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 230000011664 signaling Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/42—One nitrogen atom
- C07D251/44—One nitrogen atom with halogen atoms attached to the two other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/42—One nitrogen atom
- C07D251/46—One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/48—Two nitrogen atoms
- C07D251/50—Two nitrogen atoms with a halogen atom attached to the third ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/48—Two nitrogen atoms
- C07D251/52—Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/70—Other substituted melamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32414701P | 2001-09-21 | 2001-09-21 | |
| PCT/US2002/030177 WO2003024926A2 (en) | 2001-09-21 | 2002-09-23 | Methods and compositions of novel triazine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0212895A true BR0212895A (pt) | 2005-05-10 |
Family
ID=23262298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0212895-0A BR0212895A (pt) | 2001-09-21 | 2002-09-23 | Métodos e composições de novos compostos de triazina |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1436266A4 (is) |
| JP (1) | JP2005511509A (is) |
| KR (1) | KR20040088457A (is) |
| CN (1) | CN1578773A (is) |
| BR (1) | BR0212895A (is) |
| CA (1) | CA2461074A1 (is) |
| EA (1) | EA009728B1 (is) |
| IL (1) | IL160984A0 (is) |
| IS (1) | IS7190A (is) |
| MX (1) | MXPA04002680A (is) |
| NO (1) | NO20041187L (is) |
| NZ (1) | NZ532349A (is) |
| PL (1) | PL369600A1 (is) |
| RS (1) | RS34004A (is) |
| WO (1) | WO2003024926A2 (is) |
| ZA (1) | ZA200403009B (is) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7169785B2 (en) | 2001-09-21 | 2007-01-30 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| US7163943B2 (en) | 2001-09-21 | 2007-01-16 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| US7132423B2 (en) | 2001-09-21 | 2006-11-07 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| US7112587B2 (en) | 2001-09-21 | 2006-09-26 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| US7173032B2 (en) | 2001-09-21 | 2007-02-06 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| ATE511858T1 (de) | 2002-02-05 | 2011-06-15 | Astellas Pharma Inc | 2,4,6-triamino-1,3,5-triazin-derivat |
| WO2004001018A2 (en) * | 2002-06-25 | 2003-12-31 | The Center For Blood Research, Inc. | Vacuolins |
| WO2005009980A1 (en) * | 2003-07-22 | 2005-02-03 | Neurogen Corporation | Substituted pyridin-2-ylamine analogues |
| CN1629157A (zh) * | 2003-12-19 | 2005-06-22 | 中国科学院上海药物研究所 | 哌嗪三嗪类化合物、其制备方法及药物组合物 |
| US7335770B2 (en) | 2004-03-24 | 2008-02-26 | Reddy U5 Therapeutics, Inc. | Triazine compounds and their analogs, compositions, and methods |
| DE602007008949D1 (de) * | 2006-11-03 | 2010-10-14 | Nerviano Medical Sciences Srl | Verfahren zur verabreichung einer antitumoralen verbindung |
| KR101314869B1 (ko) * | 2010-07-29 | 2013-10-04 | 광주과학기술원 | 트리아진계 화합물을 유효성분으로 포함하는 당뇨병 예방 또는 치료용 약제학적 조성물 |
| WO2012074999A1 (en) * | 2010-11-29 | 2012-06-07 | Galleon Pharmaceuticals, Inc. | Novel compounds as respiratory stimulants for treatment of breathing control disorders or diseases |
| US20120295911A1 (en) | 2010-11-29 | 2012-11-22 | Galleon Pharmaceuticals, Inc. | Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases |
| JP6938510B2 (ja) | 2015-12-24 | 2021-09-22 | ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア | Ｃｆｔｒ制御因子及びこの使用方法 |
| CN111629730A (zh) | 2017-08-24 | 2020-09-04 | 加利福尼亚大学董事会 | 眼部药物组合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2083568C1 (ru) * | 1994-05-05 | 1997-07-10 | Кубанский государственный аграрный университет | Соли триазинкарбоновых кислот и средство для предпосевной обработки семян сельскохозяйственных культур |
| DE19531084A1 (de) * | 1995-08-24 | 1997-02-27 | Hoechst Schering Agrevo Gmbh | 2,4-Diamino-1,3,5-triazine, Verfahren zu deren Herstellung und deren Verwendung als Herbizide und Pflanzenwachstumsregulatoren |
| HUP0202076A3 (en) * | 1997-12-12 | 2003-12-29 | Abbott Lab | Triazine angiogenesis inhibitors |
| EP0945447A1 (en) * | 1998-03-27 | 1999-09-29 | Janssen Pharmaceutica N.V. | Trisubstituted 1,3,5-triazine derivatives for treatment of HIV infections |
| EP1246823A1 (en) * | 1999-12-28 | 2002-10-09 | Pharmacopeia, Inc. | Pyrimidine and triazine kinase inhibitors |
| WO2002036578A2 (en) * | 2000-10-31 | 2002-05-10 | Lynn Bonham | Triazine derivatives as lpaat-b inhibitors and uses thereof |
-
2002
- 2002-09-23 KR KR10-2004-7004179A patent/KR20040088457A/ko not_active Ceased
- 2002-09-23 IL IL16098402A patent/IL160984A0/xx unknown
- 2002-09-23 NZ NZ532349A patent/NZ532349A/en unknown
- 2002-09-23 CA CA002461074A patent/CA2461074A1/en not_active Abandoned
- 2002-09-23 CN CNA028232402A patent/CN1578773A/zh active Pending
- 2002-09-23 BR BR0212895-0A patent/BR0212895A/pt not_active IP Right Cessation
- 2002-09-23 PL PL02369600A patent/PL369600A1/xx not_active Application Discontinuation
- 2002-09-23 JP JP2003528774A patent/JP2005511509A/ja active Pending
- 2002-09-23 MX MXPA04002680A patent/MXPA04002680A/es active IP Right Grant
- 2002-09-23 WO PCT/US2002/030177 patent/WO2003024926A2/en not_active Ceased
- 2002-09-23 RS YU34004A patent/RS34004A/sr unknown
- 2002-09-23 EP EP02799019A patent/EP1436266A4/en not_active Withdrawn
- 2002-09-23 EA EA200400464A patent/EA009728B1/ru not_active IP Right Cessation
-
2004
- 2004-03-19 IS IS7190A patent/IS7190A/is unknown
- 2004-03-22 NO NO20041187A patent/NO20041187L/no not_active Application Discontinuation
- 2004-04-20 ZA ZA200403009A patent/ZA200403009B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1578773A (zh) | 2005-02-09 |
| EP1436266A4 (en) | 2004-12-22 |
| WO2003024926A2 (en) | 2003-03-27 |
| EA200400464A1 (ru) | 2005-02-24 |
| EP1436266A2 (en) | 2004-07-14 |
| CA2461074A1 (en) | 2003-03-27 |
| RS34004A (sr) | 2006-10-27 |
| ZA200403009B (en) | 2007-12-27 |
| WO2003024926A3 (en) | 2003-12-11 |
| EA009728B1 (ru) | 2008-02-28 |
| NO20041187L (no) | 2004-05-19 |
| MXPA04002680A (es) | 2004-06-18 |
| IL160984A0 (en) | 2004-08-31 |
| IS7190A (is) | 2004-03-19 |
| PL369600A1 (en) | 2005-05-02 |
| KR20040088457A (ko) | 2004-10-16 |
| JP2005511509A (ja) | 2005-04-28 |
| NZ532349A (en) | 2007-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2060 DE 29/06/2010. |