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BR0206361A - Método de terapia de reposição de hormÈnio e sua forma de administração - Google Patents

Método de terapia de reposição de hormÈnio e sua forma de administração

Info

Publication number
BR0206361A
BR0206361A BR0206361-1A BR0206361A BR0206361A BR 0206361 A BR0206361 A BR 0206361A BR 0206361 A BR0206361 A BR 0206361A BR 0206361 A BR0206361 A BR 0206361A
Authority
BR
Brazil
Prior art keywords
hormone
administration
daily
ingestion
period
Prior art date
Application number
BR0206361-1A
Other languages
English (en)
Inventor
Hermann Kulmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of BR0206361A publication Critical patent/BR0206361A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"MéTODO DE TERAPIA DE REPOSIçãO DE HORMÈNIO E SUA FORMA DE ADMINISTRAçãO". A invenção refere-se a um método para terapia de reposição de hormónio, em que pelo menos na pós-menopausa estabelecida uma unidade diária com pelo menos um componente hormonal, a saber com pelo menos estrogênio (E) e/ou pelo menos um gestágeno (G) é administrado permanentemente e continuamente a cada dia, caracterizado pelo fato de que em pelo menos um período de ingestão que precede a administração permanente de unidades diárias de hormónio é provido uma pausa de ingestão (P), em que ou nenhuma unidade diária ou placebos ou unidades diárias com um teor de estrogênio e/ou gestágeno muito menor do que durante a administração permanente de unidades diárias de hormónio na pós-menopausa estabelecida e durante a(s) fase(s) de ingestão do período de ingestão precedente são administradas, bem como forma de administração para terapia de hormónio.
BR0206361-1A 2001-01-11 2002-01-08 Método de terapia de reposição de hormÈnio e sua forma de administração BR0206361A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10100911A DE10100911A1 (de) 2001-01-11 2001-01-11 Verfahren zur Hormonersatztherapie und dessen Darreichungsform
PCT/EP2002/000089 WO2002055086A2 (en) 2001-01-11 2002-01-08 Hormone replacement therapy method and its administration form

Publications (1)

Publication Number Publication Date
BR0206361A true BR0206361A (pt) 2004-02-17

Family

ID=7670195

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0206361-1A BR0206361A (pt) 2001-01-11 2002-01-08 Método de terapia de reposição de hormÈnio e sua forma de administração

Country Status (21)

Country Link
US (1) US7871994B2 (pt)
EP (1) EP1372665B1 (pt)
JP (1) JP2004525883A (pt)
AR (1) AR033413A1 (pt)
AT (1) ATE348620T1 (pt)
AU (1) AU2007202118A1 (pt)
BR (1) BR0206361A (pt)
CA (1) CA2433656A1 (pt)
CY (1) CY1106374T1 (pt)
DE (2) DE10100911A1 (pt)
DK (1) DK1372665T3 (pt)
ES (1) ES2278896T3 (pt)
IL (1) IL156655A0 (pt)
MX (1) MXPA03006157A (pt)
NO (1) NO20033155L (pt)
NZ (1) NZ539581A (pt)
PE (1) PE20020795A1 (pt)
PT (1) PT1372665E (pt)
UY (1) UY27117A1 (pt)
WO (1) WO2002055086A2 (pt)
ZA (1) ZA200306120B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ538342A (en) * 2002-08-28 2007-08-31 Robert Casper Estrogen replacement regimen
US7786101B2 (en) 2002-11-05 2010-08-31 Bayer Schering Pharma Ag Cardiovascular protection using anti-aldosteronic progestins
AU2002368326A1 (en) * 2002-11-05 2004-06-07 Schering Aktiengesellschaft Hormone replacement therapy with drospirenone
WO2004041289A1 (en) * 2002-11-05 2004-05-21 Schering Aktiengesellschaft Cardiovascular protection using anti-aldosteronic progestins
DK1670440T3 (da) 2003-09-29 2014-07-07 Novo Nordisk As HRT formuleringer
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
DE4224534A1 (de) 1992-07-24 1994-01-27 Marika Dr Med Ehrlich Ovulationshemmendes Mittel zur hormonalen Kontrazeption
DE4405590C1 (de) 1994-02-22 1995-07-20 Hesch Rolf Dieter Prof Dr Med Mittel zur postmenopausalen Hormonbehandlung
DE4405591C1 (de) 1994-02-22 1995-07-20 Hesch Rolf Dieter Prof Dr Med Mittel zur postmenopausalen Hormonsubstitution
DE19513662A1 (de) * 1995-04-08 1996-10-10 Schering Ag Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption
DE19539233A1 (de) 1995-10-21 1997-04-24 Klaus Dr Med Umbreit Oral einzunehmendes ovulationshemmendes Mittel

Also Published As

Publication number Publication date
PT1372665E (pt) 2007-03-30
DE60216899D1 (de) 2007-02-01
EP1372665A2 (en) 2004-01-02
DK1372665T3 (da) 2007-04-30
NZ539581A (en) 2007-07-27
US20040106586A1 (en) 2004-06-03
AU2007202118A1 (en) 2007-05-31
PE20020795A1 (es) 2002-10-03
DE10100911A1 (de) 2002-08-01
MXPA03006157A (es) 2003-09-16
ZA200306120B (en) 2004-09-08
NO20033155D0 (no) 2003-07-10
CA2433656A1 (en) 2002-07-18
DE60216899T2 (de) 2007-10-25
CY1106374T1 (el) 2011-10-12
IL156655A0 (en) 2004-01-04
WO2002055086A3 (en) 2003-10-16
ES2278896T3 (es) 2007-08-16
ATE348620T1 (de) 2007-01-15
US7871994B2 (en) 2011-01-18
AR033413A1 (es) 2003-12-17
UY27117A1 (es) 2002-07-31
EP1372665B1 (en) 2006-12-20
WO2002055086A2 (en) 2002-07-18
JP2004525883A (ja) 2004-08-26
NO20033155L (no) 2003-09-10

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.