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BR0113350A - Aminoalquenilbenzoil-benzofuranos ou benzotiofenos, seu processo de preparação e as composições que os contêm - Google Patents

Aminoalquenilbenzoil-benzofuranos ou benzotiofenos, seu processo de preparação e as composições que os contêm

Info

Publication number
BR0113350A
BR0113350A BR0113350-0A BR0113350A BR0113350A BR 0113350 A BR0113350 A BR 0113350A BR 0113350 A BR0113350 A BR 0113350A BR 0113350 A BR0113350 A BR 0113350A
Authority
BR
Brazil
Prior art keywords
aminoalkenylbenzoylbenzofurans
benzothiophenes
preparation process
compositions containing
benzotiophenes
Prior art date
Application number
BR0113350-0A
Other languages
English (en)
Inventor
Jean-Louis Assens
Claude Bernhart
Frederique Cabanel-Haudricourt
Victor Dos Santos
Patrick Gautier
Dino Nisato
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of BR0113350A publication Critical patent/BR0113350A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"AMINOALQUENILBENZOIL-BENZOFURANOS OU BENZOTIOFENOS, SEU PROCESSO DE PREPARAçãO E AS COMPOSIçõES QUE OS CONTêM". A invenção refere-se a novos derivados de aminoalquenilbenzoil-benzofuranos ou benzotiofenos de fórmula geral (I). Esses compostos são úteis como medicamentos notadamente no tratamento das síndromes patológicas do sistema cardiovascular.
BR0113350-0A 2000-08-23 2001-08-23 Aminoalquenilbenzoil-benzofuranos ou benzotiofenos, seu processo de preparação e as composições que os contêm BR0113350A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0010835A FR2813307B1 (fr) 2000-08-23 2000-08-23 Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
PCT/FR2001/002656 WO2002016338A1 (fr) 2000-08-23 2001-08-23 Aminoalkenylbenzoyl-benzofuranes ou benzothiophenes, leur procede de preparation et les compositions les contenant

Publications (1)

Publication Number Publication Date
BR0113350A true BR0113350A (pt) 2003-07-08

Family

ID=8853675

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113350-0A BR0113350A (pt) 2000-08-23 2001-08-23 Aminoalquenilbenzoil-benzofuranos ou benzotiofenos, seu processo de preparação e as composições que os contêm

Country Status (25)

Country Link
US (1) US6946483B2 (pt)
EP (1) EP1315708B1 (pt)
JP (1) JP4918209B2 (pt)
KR (1) KR20030023768A (pt)
CN (1) CN1471519A (pt)
AT (1) ATE273293T1 (pt)
AU (1) AU2001284154A1 (pt)
BG (1) BG107553A (pt)
BR (1) BR0113350A (pt)
CA (1) CA2415846A1 (pt)
CZ (1) CZ2003520A3 (pt)
DE (1) DE60104866T2 (pt)
EA (1) EA200300063A1 (pt)
FR (1) FR2813307B1 (pt)
HU (1) HUP0302892A3 (pt)
IL (1) IL153637A0 (pt)
IS (1) IS6676A (pt)
MA (1) MA26944A1 (pt)
MX (1) MXPA03001592A (pt)
NO (1) NO20030801L (pt)
OA (1) OA12358A (pt)
PL (1) PL362123A1 (pt)
SK (1) SK2112003A3 (pt)
WO (1) WO2002016338A1 (pt)
ZA (1) ZA200300746B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250123237A (ko) 2009-01-16 2025-08-14 엑셀리시스, 인코포레이티드 암의 치료를 위한 ｎ-（４-｛〔６，７-비스（메틸옥시）퀴놀린-4-일〕옥시｝페닐）-ｎ＇-（４-플루오로페닐）사이클로프로판-1,1-디카르복사미드의 말산염 및 그 결정형
AU2011202542A1 (en) 2010-07-14 2012-02-02 Indian Institute Of Science Benzothiophene carboxamide compounds, composition and applications thereof
CN107827849B (zh) * 2017-11-14 2020-06-02 沈阳药科大学 6-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用
CN107857748B (zh) * 2017-11-14 2020-06-02 沈阳药科大学 5-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用
CN107935972B (zh) * 2017-11-14 2020-06-02 沈阳药科大学 5-[2-羟基-3-(异丙胺基)丙氧基]苯并呋喃类衍生物及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3248401A (en) * 1966-04-26 Diethylaminoe hoxybenzoyl benzofurans
US4831054A (en) * 1988-04-18 1989-05-16 Taro Pharmaceuticals, Ltd. 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
AT391316B (de) * 1988-09-15 1990-09-25 Ebewe Arzneimittel Neue thienyloxy-alkylamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
US5364880A (en) * 1993-06-16 1994-11-15 Advanced Therapies, Inc. Compound for treatment of cardiac arrhythmia, synthesis, and methods of use
US6756388B1 (en) * 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US5523309A (en) * 1995-03-10 1996-06-04 Eli Lilly And Company Benzofuran pharmaceutical compounds
US5622974A (en) * 1995-03-10 1997-04-22 Eli Lilly And Company α-substituted-3-benzyl-benzofurans
ATE198477T1 (de) * 1995-06-26 2001-01-15 Lilly Co Eli Benzothiophenderivate
US5827876A (en) * 1996-04-09 1998-10-27 American Home Products Corporation Inhibition of bone loss by 3-(4-acrylamidobenzoyl) benzo b!-thiophenes
WO1999054325A1 (en) * 1998-04-17 1999-10-28 Senga Pharmaceutical Laboratory Inc. 1-heteroindene derivatives and medicinal composition containing the same

Also Published As

Publication number Publication date
HUP0302892A3 (en) 2005-02-28
EP1315708A1 (fr) 2003-06-04
KR20030023768A (ko) 2003-03-19
BG107553A (en) 2004-01-30
MXPA03001592A (es) 2003-09-10
IS6676A (is) 2003-01-13
JP4918209B2 (ja) 2012-04-18
ATE273293T1 (de) 2004-08-15
AU2001284154A1 (en) 2002-03-04
WO2002016338A1 (fr) 2002-02-28
US20030187060A1 (en) 2003-10-02
HUP0302892A2 (hu) 2003-12-29
CZ2003520A3 (cs) 2003-05-14
EA200300063A1 (ru) 2003-08-28
DE60104866D1 (de) 2004-09-16
MA26944A1 (fr) 2004-12-20
PL362123A1 (en) 2004-10-18
WO2002016338A8 (fr) 2002-05-10
DE60104866T2 (de) 2005-10-20
IL153637A0 (en) 2003-07-06
JP2004506726A (ja) 2004-03-04
ZA200300746B (en) 2004-02-10
EP1315708B1 (fr) 2004-08-11
US6946483B2 (en) 2005-09-20
FR2813307A1 (fr) 2002-03-01
SK2112003A3 (en) 2003-08-05
OA12358A (fr) 2006-05-16
CA2415846A1 (fr) 2002-02-28
CN1471519A (zh) 2004-01-28
NO20030801D0 (no) 2003-02-20
NO20030801L (no) 2003-04-23
FR2813307B1 (fr) 2002-11-08

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6AE7A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008.