BR0113055A - Preparação sólida altamente absorvìvel - Google Patents
Preparação sólida altamente absorvìvelInfo
- Publication number
- BR0113055A BR0113055A BR0113055-2A BR0113055A BR0113055A BR 0113055 A BR0113055 A BR 0113055A BR 0113055 A BR0113055 A BR 0113055A BR 0113055 A BR0113055 A BR 0113055A
- Authority
- BR
- Brazil
- Prior art keywords
- solid preparation
- highly absorbable
- ability
- absorbable solid
- absorbed
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- MPORYQCGWFQFLA-ONPDANIMSA-N 7-[(7s)-7-amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1r,2s)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid;trihydrate Chemical compound O.O.O.C([C@H]1N)N(C=2C(=C3C(C(C(C(O)=O)=CN3[C@H]3[C@H](C3)F)=O)=CC=2F)Cl)CC11CC1.C([C@H]1N)N(C=2C(=C3C(C(C(C(O)=O)=CN3[C@H]3[C@H](C3)F)=O)=CC=2F)Cl)CC11CC1 MPORYQCGWFQFLA-ONPDANIMSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- -1 quinolone compound Chemical class 0.000 abstract 1
- 229960003177 sitafloxacin Drugs 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
- 239000011975 tartaric acid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"PREPARAçãO SóLIDA ALTAMENTE ABSORVìVEL". Uma preparação sólida contendo como o ingrediente ativo um grande volume de um composto quinolona fracamente solúvel em água em pH em torno da neutralidade, particularmente a sitafloxacina, que é melhorado quanto à capacidade de ser absorvida por via oral e de difusão da capacidade de ser absorvida mediante a adição de um ácido orgânico, particularmente o ácido tartárico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000239233 | 2000-08-08 | ||
| PCT/JP2001/006776 WO2002011726A1 (en) | 2000-08-08 | 2001-08-07 | Highly absorbable solid preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0113055A true BR0113055A (pt) | 2003-07-08 |
Family
ID=18730805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0113055-2A BR0113055A (pt) | 2000-08-08 | 2001-08-07 | Preparação sólida altamente absorvìvel |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US6861071B2 (pt) |
| EP (1) | EP1308160A4 (pt) |
| JP (1) | JP3573287B2 (pt) |
| KR (1) | KR100878667B1 (pt) |
| CN (1) | CN1214792C (pt) |
| AR (1) | AR030128A1 (pt) |
| AU (1) | AU2001276748A1 (pt) |
| BR (1) | BR0113055A (pt) |
| CA (1) | CA2417764C (pt) |
| MX (1) | MXPA03001206A (pt) |
| NO (1) | NO323835B1 (pt) |
| RU (1) | RU2287328C2 (pt) |
| TW (1) | TWI278316B (pt) |
| WO (1) | WO2002011726A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006093353A1 (ja) * | 2005-03-03 | 2006-09-08 | Takeda Pharmaceutical Company Limited | 放出制御組成物 |
| CN113777180B (zh) * | 2020-08-12 | 2023-05-02 | 济川药业集团有限公司 | 一种同时检测西他沙星及其多种异构体杂质的方法 |
| CN113181125B (zh) * | 2021-04-27 | 2022-07-19 | 海南通用三洋药业有限公司 | 一种西他沙星片剂及其制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4968507A (en) * | 1984-06-20 | 1990-11-06 | Merck & Co., Inc. | Controlled porosity osmotic pump |
| IL90062A (en) * | 1988-04-27 | 1994-10-07 | Daiichi Seiyaku Co | Pyridonecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them |
| PL171110B1 (pl) | 1991-12-27 | 1997-03-28 | Merck & Co Inc | Sposób wytwarzania tabletki do kontrolowanego wytwarzania i uwalniania in situ dyspersji zawierajacej lek PL PL PL |
| ATE192932T1 (de) * | 1993-09-09 | 2000-06-15 | Takeda Chemical Industries Ltd | Formulierung enthaltend einen antibakteriellen und einen antiulcus wirkstoff |
| DK0688772T3 (da) * | 1994-06-16 | 1999-11-01 | Lg Chemical Ltd | Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling |
| ES2203644T3 (es) * | 1994-08-12 | 2004-04-16 | Toyama Chemical Co., Ltd. | Derivado del nuevo acido quinoloa- o naftiridonacarboxilico y su sal. |
| US5763445A (en) * | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| US6057323A (en) * | 1996-03-08 | 2000-05-02 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| US5847003A (en) * | 1996-06-04 | 1998-12-08 | Avon Products, Inc. | Oxa acids and related compounds for treating skin conditions |
| AU3691297A (en) | 1996-08-15 | 1998-03-06 | Losan Pharma Gmbh | Easy to swallow oral medicament composition |
| US6071539A (en) * | 1996-09-20 | 2000-06-06 | Ethypharm, Sa | Effervescent granules and methods for their preparation |
| EP0995746A1 (en) * | 1997-06-23 | 2000-04-26 | Yoshitomi Pharmaceutical Industries, Ltd. | Prophylactic or therapeutic agent for diseases attributable to infection with helicobacters |
| AUPO758297A0 (en) * | 1997-06-27 | 1997-07-24 | Rowe, James Baber | Control of acidic gut syndrome |
| JP4299384B2 (ja) | 1997-07-15 | 2009-07-22 | 富山化学工業株式会社 | 溶出遅延防止細粒剤 |
| JP4299385B2 (ja) | 1997-07-15 | 2009-07-22 | 富山化学工業株式会社 | パズフロキサシン細粒剤 |
| IN186245B (pt) * | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
| ATE245414T1 (de) | 1998-09-14 | 2003-08-15 | Ranbaxy Lab Ltd | Oral verabreichtes system zur zeitlich und räumlich gesteuerten arzneistoffabgabe |
-
2001
- 2001-08-07 CA CA002417764A patent/CA2417764C/en not_active Expired - Fee Related
- 2001-08-07 AU AU2001276748A patent/AU2001276748A1/en not_active Abandoned
- 2001-08-07 MX MXPA03001206A patent/MXPA03001206A/es active IP Right Grant
- 2001-08-07 JP JP2002517062A patent/JP3573287B2/ja not_active Expired - Fee Related
- 2001-08-07 CN CNB018136737A patent/CN1214792C/zh not_active Expired - Fee Related
- 2001-08-07 US US10/344,044 patent/US6861071B2/en not_active Expired - Fee Related
- 2001-08-07 WO PCT/JP2001/006776 patent/WO2002011726A1/ja not_active Ceased
- 2001-08-07 KR KR1020037000207A patent/KR100878667B1/ko not_active Expired - Fee Related
- 2001-08-07 EP EP01954486A patent/EP1308160A4/en not_active Withdrawn
- 2001-08-07 RU RU2003106393/15A patent/RU2287328C2/ru not_active IP Right Cessation
- 2001-08-07 AR ARP010103772A patent/AR030128A1/es unknown
- 2001-08-07 BR BR0113055-2A patent/BR0113055A/pt not_active Application Discontinuation
- 2001-08-08 TW TW090119336A patent/TWI278316B/zh not_active IP Right Cessation
-
2003
- 2003-02-07 NO NO20030626A patent/NO323835B1/no not_active IP Right Cessation
- 2003-12-19 US US10/739,015 patent/US20040132756A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030176452A1 (en) | 2003-09-18 |
| NO20030626D0 (no) | 2003-02-07 |
| NO323835B1 (no) | 2007-07-09 |
| NO20030626L (no) | 2003-02-07 |
| KR20030040348A (ko) | 2003-05-22 |
| EP1308160A4 (en) | 2005-01-19 |
| AU2001276748A1 (en) | 2002-02-18 |
| AR030128A1 (es) | 2003-08-13 |
| TWI278316B (en) | 2007-04-11 |
| MXPA03001206A (es) | 2003-06-30 |
| CA2417764C (en) | 2009-05-05 |
| CN1214792C (zh) | 2005-08-17 |
| CN1444480A (zh) | 2003-09-24 |
| US20040132756A1 (en) | 2004-07-08 |
| EP1308160A1 (en) | 2003-05-07 |
| WO2002011726A1 (en) | 2002-02-14 |
| RU2287328C2 (ru) | 2006-11-20 |
| KR100878667B1 (ko) | 2009-01-13 |
| CA2417764A1 (en) | 2002-02-14 |
| US6861071B2 (en) | 2005-03-01 |
| JP3573287B2 (ja) | 2004-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) DA LPI |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |