BR0111869A - Compostos cìclicos fundidos como moduladores da função do receptor para homÈnio nuclear - Google Patents
Compostos cìclicos fundidos como moduladores da função do receptor para homÈnio nuclearInfo
- Publication number
- BR0111869A BR0111869A BR0111869-2A BR0111869A BR0111869A BR 0111869 A BR0111869 A BR 0111869A BR 0111869 A BR0111869 A BR 0111869A BR 0111869 A BR0111869 A BR 0111869A
- Authority
- BR
- Brazil
- Prior art keywords
- nuclear
- modulators
- cyclic compounds
- homonium
- receptor function
- Prior art date
Links
- 150000001923 cyclic compounds Chemical class 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000007399 Nuclear hormone receptor Human genes 0.000 abstract 1
- 108020005497 Nuclear hormone receptor Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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Abstract
"COMPOSTOS CìCLICOS FUNDIDOS COMO MODULADORES DA FUNçãO DO RECEPTOR PARA HORMÈNIO NUCLEAR". Compostos cíclicos fundidos, métodos de usar tais compostos no tratamento de condições associadas com o receptor para hormónio nuclear, tais como o câncer e os distúrbios imunológicos, e composições farmacêuticas contendo tais compostos.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21439200P | 2000-06-28 | 2000-06-28 | |
| US28443801P | 2001-04-18 | 2001-04-18 | |
| US28461701P | 2001-04-18 | 2001-04-18 | |
| PCT/US2001/019663 WO2002000653A2 (en) | 2000-06-28 | 2001-06-20 | Fused cyclic compounds as modulators of nuclear hormone receptor function |
Publications (1)
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| BR0111869A true BR0111869A (pt) | 2003-09-23 |
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| BR0111869-2A BR0111869A (pt) | 2000-06-28 | 2001-06-20 | Compostos cìclicos fundidos como moduladores da função do receptor para homÈnio nuclear |
Country Status (10)
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|---|---|
| EP (1) | EP1299385A2 (pt) |
| JP (1) | JP2004515462A (pt) |
| AU (1) | AU2002215609A1 (pt) |
| BR (1) | BR0111869A (pt) |
| CA (1) | CA2413683A1 (pt) |
| HU (1) | HUP0303165A3 (pt) |
| MX (1) | MXPA02012563A (pt) |
| NO (1) | NO20026167D0 (pt) |
| NZ (1) | NZ523802A (pt) |
| WO (1) | WO2002000653A2 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000264876A (ja) * | 1998-09-10 | 2000-09-26 | Sumitomo Chem Co Ltd | 縮合複素環化合物 |
| BR0111298A (pt) | 2000-06-28 | 2005-05-10 | Bristol Myers Squibb Co | Moduladores seletivos dos receptores de andrógenos e métodos para identificação, projeto e uso dos mesmos |
| US7001911B2 (en) | 2000-06-28 | 2006-02-21 | Bristol-Myers Squibb Company | Fused cyclic modulators of nuclear hormone receptor function |
| US20040077605A1 (en) | 2001-06-20 | 2004-04-22 | Salvati Mark E. | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
| US20030114420A1 (en) * | 2000-06-28 | 2003-06-19 | Salvati Mark E. | Fused cyclic modulators of nuclear hormone receptor function |
| AU8852901A (en) * | 2000-09-07 | 2002-03-22 | Bayer Corporation | Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binding agents |
| US6953679B2 (en) | 2000-09-19 | 2005-10-11 | Bristol-Myers Squibb Company | Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof |
| DE10162375A1 (de) * | 2001-12-19 | 2003-07-10 | Bayer Ag | Bicyclische N-Aryl-amide |
| AU2002364082A1 (en) | 2001-12-19 | 2003-07-09 | Bristol-Myers Squibb Company | Fused heterocyclic compounds and analogs thereof: modulators of nuclear hormone receptor function |
| JP2005523302A (ja) * | 2002-03-18 | 2005-08-04 | ファルマシア・コーポレーション | アルドステロン受容体アンタゴニストおよびフィブリン酸誘導体の併用 |
| US7405234B2 (en) | 2002-05-17 | 2008-07-29 | Bristol-Myers Squibb Company | Bicyclic modulators of androgen receptor function |
| EP1553074B1 (en) | 2002-08-12 | 2014-06-18 | Takeda Pharmaceutical Company Limited | Fused benzene derivative and use |
| EP1567487A4 (en) | 2002-11-15 | 2005-11-16 | Bristol Myers Squibb Co | OPEN-CHAINED, PROLYL-FROSTED MODULATORS OF ANDROGEN RECEPTOR FUNCTION |
| US7199125B2 (en) | 2003-10-02 | 2007-04-03 | Bristol-Myers Squibb Company | Spiro-cyclic compounds useful as anti-inflammatory agents |
| US7820702B2 (en) | 2004-02-04 | 2010-10-26 | Bristol-Myers Squibb Company | Sulfonylpyrrolidine modulators of androgen receptor function and method |
| US7417040B2 (en) | 2004-03-01 | 2008-08-26 | Bristol-Myers Squibb Company | Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 |
| US7696241B2 (en) | 2004-03-04 | 2010-04-13 | Bristol-Myers Squibb Company | Bicyclic compounds as modulators of androgen receptor function and method |
| US7625923B2 (en) | 2004-03-04 | 2009-12-01 | Bristol-Myers Squibb Company | Bicyclic modulators of androgen receptor function |
| US9409856B2 (en) | 2005-11-28 | 2016-08-09 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US8546451B2 (en) | 2005-11-28 | 2013-10-01 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| CA2642205C (en) * | 2006-02-10 | 2015-01-27 | Janssen Pharmaceutica N.V. | Bicyclic imidazole or thiadiazole heterocycles useful as selective androgen receptor modulators |
| EP2039695A4 (en) | 2006-07-11 | 2010-09-15 | Takeda Pharmaceutical | BICYCLIC HETEROCYLIC COMPOUND AND ITS USE |
| EP2334683B1 (en) | 2008-08-29 | 2017-03-22 | MSD Italia S.r.l. | Saturated bicyclic heterocyclic derivatives as smo antagonists |
| US9624161B2 (en) | 2009-02-23 | 2017-04-18 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US9427418B2 (en) | 2009-02-23 | 2016-08-30 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ300739A (en) * | 1994-12-22 | 2000-05-26 | Ligand Pharm Inc | Steroid receptor modulator compounds |
| ATE209207T1 (de) * | 1996-06-27 | 2001-12-15 | Ligand Pharm Inc | Androgen rezeptor modulator verbindungen und verfahren |
| BR0111298A (pt) * | 2000-06-28 | 2005-05-10 | Bristol Myers Squibb Co | Moduladores seletivos dos receptores de andrógenos e métodos para identificação, projeto e uso dos mesmos |
-
2001
- 2001-06-20 CA CA002413683A patent/CA2413683A1/en not_active Abandoned
- 2001-06-20 HU HU0303165A patent/HUP0303165A3/hu unknown
- 2001-06-20 BR BR0111869-2A patent/BR0111869A/pt not_active IP Right Cessation
- 2001-06-20 AU AU2002215609A patent/AU2002215609A1/en not_active Abandoned
- 2001-06-20 NZ NZ523802A patent/NZ523802A/en unknown
- 2001-06-20 MX MXPA02012563A patent/MXPA02012563A/es unknown
- 2001-06-20 WO PCT/US2001/019663 patent/WO2002000653A2/en not_active Ceased
- 2001-06-20 JP JP2002505777A patent/JP2004515462A/ja active Pending
- 2001-06-20 EP EP01984054A patent/EP1299385A2/en not_active Withdrawn
-
2002
- 2002-12-20 NO NO20026167A patent/NO20026167D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002000653A2 (en) | 2002-01-03 |
| JP2004515462A (ja) | 2004-05-27 |
| HUP0303165A2 (hu) | 2003-12-29 |
| EP1299385A2 (en) | 2003-04-09 |
| NZ523802A (en) | 2005-11-25 |
| MXPA02012563A (es) | 2003-05-14 |
| WO2002000653A3 (en) | 2002-07-25 |
| NO20026167L (no) | 2002-12-20 |
| CA2413683A1 (en) | 2002-01-03 |
| NO20026167D0 (no) | 2002-12-20 |
| HUP0303165A3 (en) | 2006-05-29 |
| AU2002215609A1 (en) | 2002-01-08 |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 6A., 7A., E 8A. ANUIDADES. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2008 DE 30/06/2009. |