BR0110548A - Composto, processo para a preparação do mesmo, composição farmacêutica, método de tratamento de distúrbios mediados pelo receptor de neuropeptìdio y5 em um animal de sangue quente, método de tratamento de distúrbios da alimentação em um animal de sangue quente, método para promover perda de peso em um animal de sangue quente, e, uso de um composto ou de um seu sal, prodroga ou solvato farmacêuticamente aceitável - Google Patents
Composto, processo para a preparação do mesmo, composição farmacêutica, método de tratamento de distúrbios mediados pelo receptor de neuropeptìdio y5 em um animal de sangue quente, método de tratamento de distúrbios da alimentação em um animal de sangue quente, método para promover perda de peso em um animal de sangue quente, e, uso de um composto ou de um seu sal, prodroga ou solvato farmacêuticamente aceitávelInfo
- Publication number
- BR0110548A BR0110548A BR0110548-5A BR0110548A BR0110548A BR 0110548 A BR0110548 A BR 0110548A BR 0110548 A BR0110548 A BR 0110548A BR 0110548 A BR0110548 A BR 0110548A
- Authority
- BR
- Brazil
- Prior art keywords
- warm
- blooded animal
- compound
- treating
- solvate
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 230000001404 mediated effect Effects 0.000 title abstract 3
- 102000028517 Neuropeptide receptor Human genes 0.000 title abstract 2
- 108070000018 Neuropeptide receptor Proteins 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000012453 solvate Substances 0.000 title abstract 2
- 208000030814 Eating disease Diseases 0.000 title 1
- 208000019454 Feeding and Eating disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 235000014632 disordered eating Nutrition 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 230000001737 promoting effect Effects 0.000 title 1
- 230000004580 weight loss Effects 0.000 title 1
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"COMPOSTO, PROCESSO PARA A PREPARAçãO DO MESMO, COMPOSIçãO FARMACêUTICA, MéTODO DE TRATAMENTO DE DISTúRBIOS MEDIADOS PELO RECEPTOR DE NEUROPEPTìDIO Y5 EM UM ANIMAL DE SANGUE QUENTE, MéTODO DE TRATAMENTO DE DISTúRBIOS DA ALIMENTAçãO EM UM DE SANGUE QUENTE, MéTODO PARA PROMOVER PERDA DE PESO EM UM DE SANGUE QUENTE, E, USO DE UM COMPOSTO OU DE UM SEU SAL, PRODROGA OU SOLVATO FARMACEUTICAMENTE ACEITáVEL". Descreve-se compostos da fórmula (I), em que X é um grupo da fórmula (A) ou (B) e R^ 1^,R^ 2^, R^ 3^, R^ 4^, x, y e z são definidos aqui. Descreve-se também processos para sua preparação e seu uso no tratamento de distúrbios mediados pelo receptor de neuropeptídio Y5 e m um animal de sangue quente, como um ser humano.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0010757.3A GB0010757D0 (en) | 2000-05-05 | 2000-05-05 | Chemical compounds |
| PCT/GB2001/001899 WO2001085714A1 (en) | 2000-05-05 | 2001-05-01 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by the np y5 receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0110548A true BR0110548A (pt) | 2003-04-01 |
Family
ID=9890945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0110548-5A BR0110548A (pt) | 2000-05-05 | 2001-05-01 | Composto, processo para a preparação do mesmo, composição farmacêutica, método de tratamento de distúrbios mediados pelo receptor de neuropeptìdio y5 em um animal de sangue quente, método de tratamento de distúrbios da alimentação em um animal de sangue quente, método para promover perda de peso em um animal de sangue quente, e, uso de um composto ou de um seu sal, prodroga ou solvato farmacêuticamente aceitável |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US6967216B2 (pt) |
| EP (1) | EP1278739A1 (pt) |
| JP (1) | JP2003532723A (pt) |
| KR (1) | KR20020093975A (pt) |
| CN (1) | CN1440401A (pt) |
| AR (1) | AR028414A1 (pt) |
| AU (1) | AU2001252372A1 (pt) |
| BR (1) | BR0110548A (pt) |
| CA (1) | CA2406634A1 (pt) |
| GB (1) | GB0010757D0 (pt) |
| IL (1) | IL152230A0 (pt) |
| MX (1) | MXPA02010563A (pt) |
| NO (1) | NO20025286D0 (pt) |
| NZ (1) | NZ522188A (pt) |
| WO (1) | WO2001085714A1 (pt) |
| ZA (1) | ZA200208674B (pt) |
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-
2000
- 2000-05-05 GB GBGB0010757.3A patent/GB0010757D0/en not_active Ceased
-
2001
- 2001-05-01 IL IL15223001A patent/IL152230A0/xx unknown
- 2001-05-01 US US10/275,529 patent/US6967216B2/en not_active Expired - Fee Related
- 2001-05-01 CN CN01812237A patent/CN1440401A/zh active Pending
- 2001-05-01 MX MXPA02010563A patent/MXPA02010563A/es unknown
- 2001-05-01 KR KR1020027014772A patent/KR20020093975A/ko not_active Withdrawn
- 2001-05-01 BR BR0110548-5A patent/BR0110548A/pt not_active IP Right Cessation
- 2001-05-01 JP JP2001582315A patent/JP2003532723A/ja active Pending
- 2001-05-01 CA CA002406634A patent/CA2406634A1/en not_active Abandoned
- 2001-05-01 EP EP01925687A patent/EP1278739A1/en not_active Withdrawn
- 2001-05-01 NZ NZ522188A patent/NZ522188A/en unknown
- 2001-05-01 WO PCT/GB2001/001899 patent/WO2001085714A1/en not_active Ceased
- 2001-05-01 AU AU2001252372A patent/AU2001252372A1/en not_active Abandoned
- 2001-05-04 AR ARP010102135A patent/AR028414A1/es not_active Application Discontinuation
-
2002
- 2002-10-25 ZA ZA200208674A patent/ZA200208674B/en unknown
- 2002-11-04 NO NO20025286A patent/NO20025286D0/no not_active Application Discontinuation
-
2005
- 2005-05-12 US US11/127,582 patent/US7332492B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO20025286L (no) | 2002-11-04 |
| IL152230A0 (en) | 2003-05-29 |
| US20050209233A1 (en) | 2005-09-22 |
| ZA200208674B (en) | 2004-02-10 |
| NZ522188A (en) | 2004-04-30 |
| EP1278739A1 (en) | 2003-01-29 |
| GB0010757D0 (en) | 2000-06-28 |
| CA2406634A1 (en) | 2001-11-15 |
| CN1440401A (zh) | 2003-09-03 |
| US20030225097A1 (en) | 2003-12-04 |
| WO2001085714A1 (en) | 2001-11-15 |
| JP2003532723A (ja) | 2003-11-05 |
| AU2001252372A1 (en) | 2001-11-20 |
| MXPA02010563A (es) | 2003-03-10 |
| US6967216B2 (en) | 2005-11-22 |
| US7332492B2 (en) | 2008-02-19 |
| AR028414A1 (es) | 2003-05-07 |
| NO20025286D0 (no) | 2002-11-04 |
| KR20020093975A (ko) | 2002-12-16 |
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