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BR0110034A - Phosphate Transport Inhibitors - Google Patents

Phosphate Transport Inhibitors

Info

Publication number
BR0110034A
BR0110034A BR0110034-3A BR0110034A BR0110034A BR 0110034 A BR0110034 A BR 0110034A BR 0110034 A BR0110034 A BR 0110034A BR 0110034 A BR0110034 A BR 0110034A
Authority
BR
Brazil
Prior art keywords
transport inhibitors
phosphate transport
phosphate
sulfonamido
aryl
Prior art date
Application number
BR0110034-3A
Other languages
Portuguese (pt)
Inventor
Joseph Weinstock
Gerald Girard
Dimitri Gaitanopoulos
Original Assignee
Smithkline Beecham Corporatiio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporatiio filed Critical Smithkline Beecham Corporatiio
Publication of BR0110034A publication Critical patent/BR0110034A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"INIBIDORES DO TRANSPORTE DE FOSFATOS". Descreve-se N-aril-2-sulfonamido-benzamidas úteis para o tratamento de insuficiência renal crónica e doença óssea urêmica."Phosphate Transport Inhibitors". N-aryl-2-sulfonamido-benzamides useful for the treatment of chronic renal failure and uremic bone disease are described.

BR0110034-3A 2000-05-12 2001-05-11 Phosphate Transport Inhibitors BR0110034A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20399500P 2000-05-12 2000-05-12
PCT/US2001/015324 WO2001087294A1 (en) 2000-05-12 2001-05-11 Phosphate transport inhibitors

Publications (1)

Publication Number Publication Date
BR0110034A true BR0110034A (en) 2003-05-27

Family

ID=22756167

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0110034-3A BR0110034A (en) 2000-05-12 2001-05-11 Phosphate Transport Inhibitors

Country Status (14)

Country Link
JP (1) JP2003533477A (en)
KR (1) KR20020093983A (en)
CN (1) CN1429108A (en)
AU (1) AU2001261471A1 (en)
BR (1) BR0110034A (en)
CA (1) CA2408667A1 (en)
CZ (1) CZ20023701A3 (en)
HU (1) HUP0302234A2 (en)
IL (1) IL152587A0 (en)
MX (1) MXPA02011160A (en)
NO (1) NO20025399D0 (en)
PL (1) PL359931A1 (en)
WO (1) WO2001087294A1 (en)
ZA (1) ZA200209106B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2378179A (en) * 2001-08-03 2003-02-05 Pantherix Ltd Aromatic sulfonamides and their use in treating bacterial diseases
US7119120B2 (en) * 2001-12-26 2006-10-10 Genzyme Corporation Phosphate transport inhibitors
WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
KR20200111230A (en) 2008-12-31 2020-09-28 알데릭스, 인코포레이티드 Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
BR112015003527A2 (en) 2012-08-21 2017-07-04 Ardelyx Inc compounds and methods for nhe-mediated antiport inhibition in the treatment of disorders associated with fluid retention or salt overload and disorders of the gastrointestinal tract.
US10376481B2 (en) 2012-08-21 2019-08-13 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
CN103183623A (en) * 2013-03-12 2013-07-03 中国医学科学院医药生物技术研究所 A group of benzene sulfonamido benzamide derivatives, and preparation and application thereof
RS58969B1 (en) * 2013-04-12 2019-08-30 Ardelyx Inc Nhe3-binding compounds and methods for inhibiting phosphate transport
US9765050B2 (en) 2014-12-30 2017-09-19 Novira Therapeutics, Inc. Pyridyl reverse sulfonamides for HBV treatment
CN105395532B (en) * 2015-11-25 2017-11-14 中国医学科学院医药生物技术研究所 Application of the 2 benzene sulfonamido benzamide compounds in liver injury protection and liver fibrosis preventing and treating
WO2018043400A1 (en) * 2016-08-30 2018-03-08 日本曹達株式会社 Sulfonylamino benzamide compound and pest control agent
KR20240090875A (en) 2017-01-09 2024-06-21 알데릭스, 인코포레이티드 Compounds useful for treating gastrointestinal tract disorders
CA3049679A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Inhibitors of nhe-mediated antiport
EP3802514B1 (en) * 2018-06-01 2022-08-03 Promega Corporation Inhibitors of oplophorus luciferase-derived bioluminescent complexes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20014642A3 (en) * 1999-06-24 2002-06-12 Smithkline Beecham Corporation Antagonist of macrophage catcher receptor
CO5190714A1 (en) * 1999-07-20 2002-08-29 Smithkline Beecham Corp PHOSPHATE TRANSPORTATION INHIBITORS

Also Published As

Publication number Publication date
CA2408667A1 (en) 2001-11-22
HUP0302234A2 (en) 2003-11-28
AU2001261471A1 (en) 2001-11-26
NO20025399L (en) 2002-11-11
KR20020093983A (en) 2002-12-16
WO2001087294A1 (en) 2001-11-22
CZ20023701A3 (en) 2003-11-12
JP2003533477A (en) 2003-11-11
IL152587A0 (en) 2003-05-29
MXPA02011160A (en) 2003-03-10
NO20025399D0 (en) 2002-11-11
CN1429108A (en) 2003-07-09
PL359931A1 (en) 2004-09-06
ZA200209106B (en) 2003-10-23

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]