[go: up one dir, main page]

BR0110072A - Pluripotent cells comprising allogeneic nucleus and mitochondria - Google Patents

Pluripotent cells comprising allogeneic nucleus and mitochondria

Info

Publication number
BR0110072A
BR0110072A BR0110072-6A BR0110072A BR0110072A BR 0110072 A BR0110072 A BR 0110072A BR 0110072 A BR0110072 A BR 0110072A BR 0110072 A BR0110072 A BR 0110072A
Authority
BR
Brazil
Prior art keywords
mitochondria
nucleus
pluripotent cells
allogeneic
cells
Prior art date
Application number
BR0110072-6A
Other languages
Portuguese (pt)
Inventor
Michael D West
Original Assignee
Advanced Cell Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Cell Tech Inc filed Critical Advanced Cell Tech Inc
Publication of BR0110072A publication Critical patent/BR0110072A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/166—Animal cells resulting from interspecies fusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/04—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from germ cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Environmental Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"CéLULAS PLURIPOTENTES COMPREENDENDO NúCLEO ALOGêNICO E MITOCÈNDRIA". Células ES aloquiméricas são fornecidas tendo núcleos de um indivíduo de uma espécie e mitocóndria de um indivíduo diferente da mesma espécie. As células ES podem ser usadas para diferenciação em tipos de células diferenciadas para terapia ou para estudar vários processos desenvolvimentais em formar embriões e diferenciação."PLURIPOTENT CELLS UNDERSTANDING ALLOGENIC NUCLEUS AND MYTHOCONDIA". Allochromic ES cells are provided having nuclei of one individual of one species and mitochondria of a different individual of the same species. ES cells can be used for differentiation into differentiated cell types for therapy or to study various developmental processes in embryo formation and differentiation.

BR0110072-6A 2000-04-14 2001-04-16 Pluripotent cells comprising allogeneic nucleus and mitochondria BR0110072A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19740700P 2000-04-14 2000-04-14
PCT/US2001/012265 WO2001079445A2 (en) 2000-04-14 2001-04-16 Pluripotent cells comprising allogenic nucleus and mitochondria

Publications (1)

Publication Number Publication Date
BR0110072A true BR0110072A (en) 2004-07-06

Family

ID=22729292

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0110072-6A BR0110072A (en) 2000-04-14 2001-04-16 Pluripotent cells comprising allogeneic nucleus and mitochondria

Country Status (10)

Country Link
EP (1) EP1282685A2 (en)
JP (1) JP2003530848A (en)
CN (2) CN1673361A (en)
AU (1) AU2001257053A1 (en)
BR (1) BR0110072A (en)
CA (1) CA2405555A1 (en)
IL (1) IL152064A0 (en)
MX (1) MXPA02010075A (en)
NZ (1) NZ521711A (en)
WO (1) WO2001079445A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL156746A0 (en) 2001-01-02 2004-02-08 Stemron Inc A method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom and materials and method using same
WO2003072708A2 (en) * 2002-02-21 2003-09-04 Advanced Cell Technology, Inc. Pluripotent cells comprising allogenic nucleus and mitochondria
AP2013007229A0 (en) * 2011-04-14 2013-11-30 Gen Hospital Corp Compositions and methods for autologous germline mitochondrial energy transfer
CN104830777A (en) * 2014-02-28 2015-08-12 复旦大学 Polar body genome reconstruction ovum, preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011197A (en) * 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells

Also Published As

Publication number Publication date
JP2003530848A (en) 2003-10-21
AU2001257053A1 (en) 2001-10-30
MXPA02010075A (en) 2003-02-12
NZ521711A (en) 2005-03-24
WO2001079445A3 (en) 2002-07-11
CA2405555A1 (en) 2001-10-25
EP1282685A2 (en) 2003-02-12
IL152064A0 (en) 2003-05-29
CN1673361A (en) 2005-09-28
CN1427887A (en) 2003-07-02
WO2001079445A2 (en) 2001-10-25

Similar Documents

Publication Publication Date Title
BR0305721A (en) Human stem cell, cell population, process for obtaining stem cells, for the production of differentiated cells of the mesodermal lineage, for selection that allows to identify agents susceptible to present lipolytic activity and insulin-sensitizing activity, use of a cell , stem cell utilization, pharmaceutical composition, human cell, multipotent human cell population
IL210618A (en) Cell cultures comprising isolated expanded human non-embryonic non-germ cells, pharmaceutical compositions comprising the same, methods for their preparation and methods for identifying modulators and differentiation factors
TR199901034T2 (en) N�rit b�y�mesinin uyar�lmas� i�in y�ntemler ve bile�imler.
BR0315435A (en) Cell-based vegf distribution
BR0015416A (en) Compositions containing tetraenoic hydroxyieic acid derivatives and methods of use in the treatment of dry eye disorders
DE69832402D1 (en) GENERATION OF HEMATOPOIETIC CELLS FROM MULTIPOTENTE NEURONAL STEM CELLS
DK0451611T3 (en) Human hematopoietic stem cell
FI882923L (en) In vitro embryo culture technique
EP2422801A3 (en) Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
AR036827A1 (en) KERATINOCITS USED AS A BIOLOGICALLY ACTIVE SUBSTANCE IN WOUND TREATMENT
ES2194106T3 (en) IMIDAZOL POSTS
BR9813233A (en) Stimulation of hematopoietic cells in vitro
GEP20033092B (en) Purine Inhibitors of Cyclin Dependent Kinase 2 and Ik-Aa
DE60129943D1 (en) DIFFERENTIATION OF BONE MARROW CELLS IN NEURONAL CELLS AND THEIR USES
DE60127970D1 (en) COMPOSITION CONTAINING AN ANTIFOLATE AND A METHYLMALONIC ACID SUBSTITUTING AGENT
ES2151607T3 (en) GROWTH AND DIFFERENTIATION FACTOR 12.
ATE556137T1 (en) BIOMIMETIC COMPOSITION REINFORCED BY A POLYELECTROLYTE COMPLEX OF HYALURONIC ACID AND CHITOSAN
FR2812004B1 (en) CULTURE MEDIA FOR IN VITRO FERTILIZATION, OR FOR THE CULTURE OF FOLLICLES, MALE GERMINAL CELLS OR EMBRYOS
BR0214860A (en) Cellular construct or tissue, process of preparing a cellular construct, use of a construct, method of preparing an implant with the aid of a construct, construct preparation kit, pharmaceutical composition and implant
DK1900811T3 (en) Enriched cell populations in the central nervous system
DK0952772T3 (en) Methods of using mononuclear phagocytes to promote axonal regeneration
BR0110072A (en) Pluripotent cells comprising allogeneic nucleus and mitochondria
WO2005051978A3 (en) Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof
MX9302951A (en) PHARMACEUTICAL COMPOSITION TO TREAT CELL HYPERPROLIFERATION.
DE69737455D1 (en) DEFINED SYSTEMS FOR CULTIVATING EPITHELIAL CELLS AND USE THEREOF

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO DA RPI 2016 DE 25/08/2009.