BR0109770A - Use of galantamine to treat neuropsychiatric behavior associated with alzheimer's disease - Google Patents
Use of galantamine to treat neuropsychiatric behavior associated with alzheimer's diseaseInfo
- Publication number
- BR0109770A BR0109770A BR0109770-9A BR0109770A BR0109770A BR 0109770 A BR0109770 A BR 0109770A BR 0109770 A BR0109770 A BR 0109770A BR 0109770 A BR0109770 A BR 0109770A
- Authority
- BR
- Brazil
- Prior art keywords
- alzheimer
- galantamine
- disease
- behavior associated
- treat neuropsychiatric
- Prior art date
Links
- ASUTZQLVASHGKV-JDFRZJQESA-N galanthamine Chemical compound O1C(=C23)C(OC)=CC=C2CN(C)CC[C@]23[C@@H]1C[C@@H](O)C=C2 ASUTZQLVASHGKV-JDFRZJQESA-N 0.000 title abstract 9
- 229960003980 galantamine Drugs 0.000 title abstract 5
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 4
- ASUTZQLVASHGKV-UHFFFAOYSA-N galanthamine hydrochloride Natural products O1C(=C23)C(OC)=CC=C2CN(C)CCC23C1CC(O)C=C2 ASUTZQLVASHGKV-UHFFFAOYSA-N 0.000 title abstract 4
- 208000017667 Chronic Disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
"USO DE GALANTAMINA PARA O TRATAMENTO DO COMPORTAMENTO NEUROPSIQUIáTRICO ASSOCIADO COM A DOENçA DE ALZHEIMER". A invenção refere-se a galantamina que tem sido utilizada no tratamento de um número de doenças crónicas. Foi descoberto que a galantamina é segura e eficiente no tratamento da doença de Alzheimer. Os distúrbios neuropsiquiátricos são freq³entemente associados com a doença de Alzheimer. é demonstrado que a galantamina é também eficiente na redução ou na estabilização da incidência do comportamento neuropsiquiátrico observado nos pacientes com Alzheimer."USE OF GALANTAMIN FOR TREATMENT OF NEUROPSYCHIATRIC BEHAVIOR ASSOCIATED WITH ALZHEIMER DISEASE". The invention relates to galantamine which has been used in the treatment of a number of chronic diseases. Galantamine has been found to be safe and effective in treating Alzheimer's disease. Neuropsychiatric disorders are often associated with Alzheimer's disease. galantamine is also shown to be effective in reducing or stabilizing the incidence of neuropsychiatric behavior observed in Alzheimer's patients.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19425900P | 2000-04-03 | 2000-04-03 | |
| PCT/EP2001/003553 WO2001074339A2 (en) | 2000-04-03 | 2001-03-28 | A use of galantamine for the treatment of neuropsychiatric behaviour associated with alzheimer's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0109770A true BR0109770A (en) | 2003-02-04 |
Family
ID=22716898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0109770-9A BR0109770A (en) | 2000-04-03 | 2001-03-28 | Use of galantamine to treat neuropsychiatric behavior associated with alzheimer's disease |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1272192A2 (en) |
| JP (1) | JP2003528913A (en) |
| KR (1) | KR20020086911A (en) |
| CN (1) | CN1430514A (en) |
| AU (2) | AU2001265844B2 (en) |
| BG (1) | BG107093A (en) |
| BR (1) | BR0109770A (en) |
| CA (1) | CA2310926C (en) |
| CZ (1) | CZ20023543A3 (en) |
| EE (1) | EE200200554A (en) |
| HR (1) | HRP20020778A2 (en) |
| HU (1) | HUP0300566A3 (en) |
| IL (1) | IL152061A0 (en) |
| MX (1) | MXPA02009777A (en) |
| NO (1) | NO20024746L (en) |
| PL (1) | PL361272A1 (en) |
| RU (1) | RU2002129298A (en) |
| SK (1) | SK15422002A3 (en) |
| WO (1) | WO2001074339A2 (en) |
| ZA (1) | ZA200207935B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6617361B2 (en) * | 1999-11-05 | 2003-09-09 | Be Able, Llc | Behavior chemotherapy |
| DE602004009195T2 (en) * | 2003-07-25 | 2008-06-26 | F. Hoffmann-La Roche Ag | COMBINATION OF A MGLUR2 ANTAGONISTS AND AN AXIS INHIBITOR FOR THE TREATMENT OF ACUTE AND / OR CHRONIC NEUROLOGICAL DISEASES |
| DE10338544B4 (en) * | 2003-08-19 | 2017-08-31 | Janssen Pharmaceutica N.V. | Buccal formulations of galanthamine and their applications |
| WO2009120277A1 (en) | 2008-03-27 | 2009-10-01 | Chase Pharmaceuticals Corporation | Use and composition for treating dementia |
| WO2013160728A1 (en) | 2012-04-26 | 2013-10-31 | Alma Mater Studiorum - Universita' Di Bologna | Dual targeting compounds for the treatment of alzheimer's disease |
| BG66818B1 (en) * | 2013-03-07 | 2019-01-31 | Berbee Beheer B. V. | Composition of hippeastrum papilio extract for the production of medicines and nutritional supplements |
| CN107847504A (en) * | 2015-05-18 | 2018-03-27 | 斯奈普泰克发展有限责任公司 | Galantamine clearance of amyloid beta |
| CN117957003A (en) * | 2021-09-09 | 2024-04-30 | 上海日馨医药科技股份有限公司 | Methods for treating neurodegenerative diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663318A (en) | 1986-01-15 | 1987-05-05 | Bonnie Davis | Method of treating Alzheimer's disease |
| DE19509663A1 (en) * | 1995-03-17 | 1996-09-19 | Lohmann Therapie Syst Lts | Process for the isolation of galanthamine |
| GB9600080D0 (en) * | 1996-01-04 | 1996-03-06 | Chiroscience Ltd | Resolution process |
| CA2351347A1 (en) | 1998-11-23 | 2000-06-02 | Bonnie Davis | Dosage formulations for acetylcholinesterase inhibitors |
| EE04996B1 (en) * | 1998-12-24 | 2008-04-15 | Janssen Pharmaceutica N.V. | Controlled release galantamine preparation, method of preparation, dosage form and pharmaceutical packaging |
| CA2310950C (en) * | 2000-04-03 | 2005-11-08 | Janssen Pharmaceutica N.V. | An efficacious dosage regiment of galantamine that reduces side effects |
| CA2310990A1 (en) * | 2000-04-03 | 2000-10-09 | Michael Pontecorvo | A use of galantamine for the treatment of alzheimer's disease; targeting the underlying cause of the disease |
-
2000
- 2000-06-27 CA CA002310926A patent/CA2310926C/en not_active Expired - Lifetime
-
2001
- 2001-03-28 HR HR20020778A patent/HRP20020778A2/en not_active Application Discontinuation
- 2001-03-28 AU AU2001265844A patent/AU2001265844B2/en not_active Ceased
- 2001-03-28 MX MXPA02009777A patent/MXPA02009777A/en unknown
- 2001-03-28 RU RU2002129298/14A patent/RU2002129298A/en not_active Application Discontinuation
- 2001-03-28 SK SK1542-2002A patent/SK15422002A3/en unknown
- 2001-03-28 BR BR0109770-9A patent/BR0109770A/en not_active IP Right Cessation
- 2001-03-28 WO PCT/EP2001/003553 patent/WO2001074339A2/en not_active Ceased
- 2001-03-28 AU AU6584401A patent/AU6584401A/en active Pending
- 2001-03-28 JP JP2001572084A patent/JP2003528913A/en not_active Withdrawn
- 2001-03-28 CZ CZ20023543A patent/CZ20023543A3/en unknown
- 2001-03-28 HU HU0300566A patent/HUP0300566A3/en unknown
- 2001-03-28 CN CN01807334A patent/CN1430514A/en active Pending
- 2001-03-28 EE EEP200200554A patent/EE200200554A/en unknown
- 2001-03-28 PL PL36127201A patent/PL361272A1/en not_active Application Discontinuation
- 2001-03-28 KR KR1020027011063A patent/KR20020086911A/en not_active Ceased
- 2001-03-28 IL IL15206101A patent/IL152061A0/en unknown
- 2001-03-28 EP EP01943200A patent/EP1272192A2/en not_active Withdrawn
-
2002
- 2002-09-12 BG BG107093A patent/BG107093A/en unknown
- 2002-10-02 ZA ZA200207935A patent/ZA200207935B/en unknown
- 2002-10-02 NO NO20024746A patent/NO20024746L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BG107093A (en) | 2003-06-30 |
| IL152061A0 (en) | 2003-05-29 |
| AU2001265844B2 (en) | 2005-04-14 |
| CZ20023543A3 (en) | 2003-03-12 |
| AU6584401A (en) | 2001-10-15 |
| CN1430514A (en) | 2003-07-16 |
| WO2001074339A3 (en) | 2002-09-12 |
| NO20024746D0 (en) | 2002-10-02 |
| CA2310926C (en) | 2002-10-15 |
| PL361272A1 (en) | 2004-10-04 |
| HRP20020778A2 (en) | 2004-04-30 |
| EE200200554A (en) | 2004-04-15 |
| EP1272192A2 (en) | 2003-01-08 |
| WO2001074339A2 (en) | 2001-10-11 |
| KR20020086911A (en) | 2002-11-20 |
| MXPA02009777A (en) | 2003-03-27 |
| ZA200207935B (en) | 2004-01-30 |
| HUP0300566A3 (en) | 2004-10-28 |
| NO20024746L (en) | 2002-11-28 |
| CA2310926A1 (en) | 2000-10-04 |
| SK15422002A3 (en) | 2003-04-01 |
| HUP0300566A2 (en) | 2003-06-28 |
| JP2003528913A (en) | 2003-09-30 |
| RU2002129298A (en) | 2004-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 8A. ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2016 DE 25/08/2009 |