BR0108169A - Processo para fornecer a 3,5-difluoroanilina a partir do 1,3,5-triclorobenzeno - Google Patents
Processo para fornecer a 3,5-difluoroanilina a partir do 1,3,5-triclorobenzenoInfo
- Publication number
- BR0108169A BR0108169A BR0108169-1A BR0108169A BR0108169A BR 0108169 A BR0108169 A BR 0108169A BR 0108169 A BR0108169 A BR 0108169A BR 0108169 A BR0108169 A BR 0108169A
- Authority
- BR
- Brazil
- Prior art keywords
- difluoroaniline
- trichlorobenzene
- supplying
- aminating
- fluorinating
- Prior art date
Links
- XKEFYDZQGKAQCN-UHFFFAOYSA-N 1,3,5-trichlorobenzene Chemical compound ClC1=CC(Cl)=CC(Cl)=C1 XKEFYDZQGKAQCN-UHFFFAOYSA-N 0.000 title abstract 3
- KQOIBXZRCYFZSO-UHFFFAOYSA-N 3,5-difluoroaniline Chemical compound NC1=CC(F)=CC(F)=C1 KQOIBXZRCYFZSO-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
- C07C209/10—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having nitrogen atoms bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
- C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
- C07C17/208—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being MX
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Abstract
"PROCESSO PARA FORNECER A 3,5-DIFLUOROANILINA A PARTIR DO 1,3,5-TRICLOROBENZéNO". Um método para a fabricação de 3,5-difluoroanilina pela fluoração de 1,3,5-triclorobenzeno e depois pela aminação do benzeno fluorado intermediário com amónia aquosa ou anidra para se obter o produto em rendimentos de mais do que 80%.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/500,368 US6127577A (en) | 2000-02-08 | 2000-02-08 | Method of making 3,5-difluoroaniline from 1,3,5-trichlorobenzene |
| PCT/EP2001/001079 WO2001058846A1 (en) | 2000-02-08 | 2001-02-01 | Method of making 3,5-difluoroaniline from 1,3,5-trichlorobenzene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0108169A true BR0108169A (pt) | 2003-02-25 |
Family
ID=23989099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0108169-1A BR0108169A (pt) | 2000-02-08 | 2001-02-01 | Processo para fornecer a 3,5-difluoroanilina a partir do 1,3,5-triclorobenzeno |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6127577A (pt) |
| EP (1) | EP1254103B1 (pt) |
| JP (1) | JP2003534242A (pt) |
| KR (1) | KR20020073207A (pt) |
| CN (1) | CN1400964A (pt) |
| AT (1) | ATE267796T1 (pt) |
| AU (1) | AU2001246411A1 (pt) |
| BR (1) | BR0108169A (pt) |
| CA (1) | CA2398650A1 (pt) |
| CZ (1) | CZ20022714A3 (pt) |
| DE (1) | DE60103506T2 (pt) |
| EA (1) | EA200200809A1 (pt) |
| HU (1) | HUP0204541A3 (pt) |
| IL (1) | IL150415A0 (pt) |
| MX (1) | MXPA02007606A (pt) |
| WO (1) | WO2001058846A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004033525A1 (de) * | 2004-07-08 | 2006-02-02 | Lanxess Deutschland Gmbh | Verbessertes Verfahren zur Herstellung kernfluorierter Aromaten |
| CN117486728B (zh) * | 2023-12-28 | 2024-05-17 | 山东国邦药业有限公司 | 一种高效循环的氟化试剂及其制备方法与应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4294988A (en) * | 1977-10-31 | 1981-10-13 | Merck & Co., Inc. | Method of preparing 2,4-difluoroaniline |
| US4140719A (en) * | 1977-10-31 | 1979-02-20 | Merck & Co., Inc. | Solid-liquid phase transfer catalysis improved method of preparing 2,4-difluoroaniline |
| US4145364A (en) * | 1977-11-30 | 1979-03-20 | Merck & Co., Inc. | Preparation of fluorinated anilines |
| US4343951A (en) * | 1980-12-29 | 1982-08-10 | Hooker Chemicals & Plastics Corp. | Method for the preparation of fluoroaniline |
| JPH0441466A (ja) * | 1990-06-06 | 1992-02-12 | Sds Biotech Kk | ジフルオロアニリンの製造方法 |
| US5510533A (en) * | 1990-06-06 | 1996-04-23 | Sds Biotech K.K. | Process for producing 3,5-difluoroaniline and derivative thereof |
| US5041674A (en) * | 1990-06-14 | 1991-08-20 | Dowelanco | Process and intermediates for the preparation of 2,6-difluoroaniline |
| US5116982A (en) * | 1990-08-06 | 1992-05-26 | Dowelanco | Preparation of fluorohalophenols and n-acyfluorohaloanilines |
| JPH0565250A (ja) * | 1991-01-28 | 1993-03-19 | Ishihara Sangyo Kaisha Ltd | 3,5−ジフルオロアニリンの製造方法 |
| US5091580A (en) * | 1991-03-27 | 1992-02-25 | Dowelanco | Process for the preparation of 2,6-difluoroaniline |
| US5294742A (en) * | 1992-03-21 | 1994-03-15 | Hoechst Atkiengesellschaft | Process for preparing 3,5-difluoroaniline |
| US5157169A (en) * | 1992-03-26 | 1992-10-20 | Mallinckrodt Specialty Chemicals Company | Preparation of 3-halo-halobenzenes and 1-halo-3,5-dihalobenzenes |
| GB9400569D0 (en) * | 1994-01-13 | 1994-03-09 | Rhone Poulenc Chemicals | Process for the production of substituted aromatic hydrocarbons from corresponding anilines by dediazoniation |
| ES2114237T3 (es) * | 1994-02-11 | 1998-05-16 | Clariant Gmbh | Procedimiento para la preparacion de fluoroanilinas. |
| AU4265396A (en) * | 1994-11-30 | 1996-06-19 | Rhone-Poulenc Chimie | Method for preparing fluoroanilines from nitrofluorobenzene compounds |
| DE19720341C1 (de) * | 1997-05-15 | 1998-08-27 | Clariant Gmbh | Verfahren zur Herstellung von 3,5-Difluoranilin |
-
2000
- 2000-02-08 US US09/500,368 patent/US6127577A/en not_active Expired - Fee Related
-
2001
- 2001-02-01 AT AT01919251T patent/ATE267796T1/de not_active IP Right Cessation
- 2001-02-01 DE DE60103506T patent/DE60103506T2/de not_active Expired - Lifetime
- 2001-02-01 IL IL15041501A patent/IL150415A0/xx unknown
- 2001-02-01 CN CN01804645A patent/CN1400964A/zh active Pending
- 2001-02-01 EA EA200200809A patent/EA200200809A1/ru unknown
- 2001-02-01 JP JP2001558398A patent/JP2003534242A/ja active Pending
- 2001-02-01 HU HU0204541A patent/HUP0204541A3/hu unknown
- 2001-02-01 CA CA002398650A patent/CA2398650A1/en not_active Abandoned
- 2001-02-01 BR BR0108169-1A patent/BR0108169A/pt not_active IP Right Cessation
- 2001-02-01 AU AU2001246411A patent/AU2001246411A1/en not_active Abandoned
- 2001-02-01 EP EP01919251A patent/EP1254103B1/en not_active Expired - Lifetime
- 2001-02-01 WO PCT/EP2001/001079 patent/WO2001058846A1/en not_active Ceased
- 2001-02-01 KR KR1020027010221A patent/KR20020073207A/ko not_active Withdrawn
- 2001-02-01 CZ CZ20022714A patent/CZ20022714A3/cs unknown
- 2001-02-01 MX MXPA02007606A patent/MXPA02007606A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2398650A1 (en) | 2001-08-16 |
| HUP0204541A2 (hu) | 2003-04-28 |
| ATE267796T1 (de) | 2004-06-15 |
| CN1400964A (zh) | 2003-03-05 |
| KR20020073207A (ko) | 2002-09-19 |
| US6127577A (en) | 2000-10-03 |
| EA200200809A1 (ru) | 2003-04-24 |
| HUP0204541A3 (en) | 2003-10-28 |
| CZ20022714A3 (cs) | 2003-05-14 |
| MXPA02007606A (es) | 2003-03-27 |
| WO2001058846A1 (en) | 2001-08-16 |
| JP2003534242A (ja) | 2003-11-18 |
| EP1254103B1 (en) | 2004-05-26 |
| IL150415A0 (en) | 2002-12-01 |
| AU2001246411A1 (en) | 2001-08-20 |
| DE60103506D1 (de) | 2004-07-01 |
| EP1254103A1 (en) | 2002-11-06 |
| DE60103506T2 (de) | 2004-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008. |