BR0016328A - Pró-drogas de fosfato de pseudomicina - Google Patents
Pró-drogas de fosfato de pseudomicinaInfo
- Publication number
- BR0016328A BR0016328A BR0016328-7A BR0016328A BR0016328A BR 0016328 A BR0016328 A BR 0016328A BR 0016328 A BR0016328 A BR 0016328A BR 0016328 A BR0016328 A BR 0016328A
- Authority
- BR
- Brazil
- Prior art keywords
- pseudomycin
- phosphate
- phosphate prodrugs
- prodrug
- methylenoxycarbamate
- Prior art date
Links
- 229940002612 prodrug Drugs 0.000 title abstract 4
- 239000000651 prodrug Substances 0.000 title abstract 4
- 229910019142 PO4 Inorganic materials 0.000 title abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title abstract 3
- 239000010452 phosphate Substances 0.000 title abstract 3
- 230000002411 adverse Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- YGHZBJYZWJLOHX-UHFFFAOYSA-N phenylmethoxycarbamic acid;phosphoric acid Chemical group OP(O)(O)=O.OC(=O)NOCC1=CC=CC=C1 YGHZBJYZWJLOHX-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
"PRó-DROGAS DE FOSFATO DE PSEUDOMICINA". Um pró-droga de pseudomicina representada pela estrutura (A) onde R1 é uma ligação de benziloxicarbamato de fosfato ou metilenoxicarbamato de fosfato é descrito. A pró-droga de fosfato demonstra atividade antifúngica com menos efeitos colaterais adversos que o composto de pseudomicina de origem.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17046699P | 1999-12-13 | 1999-12-13 | |
| PCT/US2000/030167 WO2001041534A2 (en) | 1999-12-13 | 2000-11-29 | Pseudomycin phosphate prodrugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0016328A true BR0016328A (pt) | 2002-08-27 |
Family
ID=22619957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0016328-7A BR0016328A (pt) | 1999-12-13 | 2000-11-29 | Pró-drogas de fosfato de pseudomicina |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JP2003515610A (pt) |
| AU (1) | AU3071801A (pt) |
| BR (1) | BR0016328A (pt) |
| CA (1) | CA2396513A1 (pt) |
| MX (1) | MXPA02005791A (pt) |
| NO (1) | NO20022798D0 (pt) |
| WO (1) | WO2001041534A2 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2369136A1 (en) * | 1999-04-15 | 2000-10-26 | Eli Lilly And Company | Pseudomycin natural products |
| BR112020013672A2 (pt) | 2018-01-05 | 2020-12-01 | Cybrexa 1, Inc. | compostos, composições, e métodos para tratamento de doenças que envolvem tecidos afetados por ácidos ou hipoxia |
| CA3146560A1 (en) | 2019-07-10 | 2021-01-14 | Cybrexa 2, Inc. | Peptide conjugates of cytotoxins as therapeutics |
| JP7675060B2 (ja) | 2019-07-10 | 2025-05-12 | サイブレクサ ３，インコーポレイテッド | 治療薬としての微小管標的化剤のペプチドコンジュゲート |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5576298A (en) * | 1992-11-30 | 1996-11-19 | Research And Development Institute, Inc. At Montana State University | Peptides from pseudomonas syringae possessing broad-spectrum antibiotic activity |
| CA2379321A1 (en) * | 1999-07-15 | 2001-01-25 | Eli Lilly And Company | Pseudomycin amide and ester analogs |
-
2000
- 2000-11-29 BR BR0016328-7A patent/BR0016328A/pt not_active Application Discontinuation
- 2000-11-29 JP JP2001542721A patent/JP2003515610A/ja not_active Withdrawn
- 2000-11-29 WO PCT/US2000/030167 patent/WO2001041534A2/en not_active Ceased
- 2000-11-29 AU AU30718/01A patent/AU3071801A/en not_active Abandoned
- 2000-11-29 MX MXPA02005791A patent/MXPA02005791A/es unknown
- 2000-11-29 CA CA002396513A patent/CA2396513A1/en not_active Abandoned
-
2002
- 2002-06-12 NO NO20022798A patent/NO20022798D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU3071801A (en) | 2001-06-18 |
| JP2003515610A (ja) | 2003-05-07 |
| WO2001041534A2 (en) | 2001-06-14 |
| NO20022798L (no) | 2002-06-12 |
| CA2396513A1 (en) | 2001-06-14 |
| NO20022798D0 (no) | 2002-06-12 |
| MXPA02005791A (es) | 2002-09-30 |
| WO2001041534A3 (en) | 2001-11-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |