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BR0011648A - Método de fabricação de imunoglobulina intravenosa e produto resultante - Google Patents

Método de fabricação de imunoglobulina intravenosa e produto resultante

Info

Publication number
BR0011648A
BR0011648A BR0011648-3A BR0011648A BR0011648A BR 0011648 A BR0011648 A BR 0011648A BR 0011648 A BR0011648 A BR 0011648A BR 0011648 A BR0011648 A BR 0011648A
Authority
BR
Brazil
Prior art keywords
globulin
gamma
resulting product
manufacturing
intravenous immunoglobulin
Prior art date
Application number
BR0011648-3A
Other languages
English (en)
Inventor
Raja R Mamidi
Andranik Bagdasarian
Gorgonio Canaveral
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Publication of BR0011648A publication Critical patent/BR0011648A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção: "MéTODO DE FABRICAçãO DE IMUNOGLOBULINA INTRAVENOSA E PRODUTO RESULTANTE". Um processo contínuo para a produção de solução de gama globulina intravenosamente administrável substancialmente sem vírus contaminantes através de tratamento com calor de uma solução de gama globulina para inativação viral, fracionamento para se obter uma solução de gama globulina purificada sem precipitação da gama globulina desejada e então tratamento da gama globulina purificada com um solvente-detergente para inativação viral adicional. Os sólidos de gama globulina parcialmente purificados não são recuperados com um produto intermediário durante o processo descrito.
BR0011648-3A 1999-06-15 2000-06-06 Método de fabricação de imunoglobulina intravenosa e produto resultante BR0011648A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33328999A 1999-06-15 1999-06-15
PCT/US2000/011870 WO2000076534A1 (en) 1999-06-15 2000-06-06 Manufacturing method for intravenous immune globulin and resultant product

Publications (1)

Publication Number Publication Date
BR0011648A true BR0011648A (pt) 2002-03-19

Family

ID=23302162

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0011648-3A BR0011648A (pt) 1999-06-15 2000-06-06 Método de fabricação de imunoglobulina intravenosa e produto resultante

Country Status (13)

Country Link
EP (1) EP1185290A4 (pt)
JP (1) JP2003501480A (pt)
KR (1) KR20020010921A (pt)
CN (1) CN1358100A (pt)
AU (1) AU756071B2 (pt)
BR (1) BR0011648A (pt)
CA (1) CA2375560A1 (pt)
CZ (1) CZ20014456A3 (pt)
HK (1) HK1048252A1 (pt)
IL (1) IL146433A0 (pt)
PL (1) PL352910A1 (pt)
WO (1) WO2000076534A1 (pt)
ZA (1) ZA200110168B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2437518A (en) * 2006-04-26 2007-10-31 Noel Kavanagh Antiserum preparation
WO2007136327A1 (en) * 2006-05-22 2007-11-29 Ge Healthcare Bio-Sciences Ab A method of producing igg
US7932356B1 (en) * 2010-06-23 2011-04-26 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition
KR101917196B1 (ko) * 2014-03-11 2018-11-09 주식회사 녹십자홀딩스 면역글로불린의 정제방법
WO2015137531A1 (ko) * 2014-03-11 2015-09-17 주식회사 녹십자홀딩스 면역글로불린의 정제방법
KR101941974B1 (ko) * 2016-11-18 2019-01-24 주식회사 녹십자 혈장 단백질 정제시 fxi의 제거방법
ES2991988T3 (es) 2017-10-30 2024-12-05 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivación de virus con envoltura lipídica

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820805A (en) * 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
FR2582515B1 (fr) * 1985-05-30 1988-11-04 Merieux Inst Procede de preparation de gamma-gobulines administrables par voie intraveineuse et gamma-globulines obtenues
JPH0662436B2 (ja) * 1986-05-19 1994-08-17 株式会社ミドリ十字 静注用免疫グロブリン製剤の製造方法
US4841023A (en) * 1986-06-25 1989-06-20 New York Blood Center, Inc. Inactivation of viruses in labile protein-containing compositions using fatty acids
EP0378208B2 (en) * 1989-01-13 2003-01-15 Mitsubishi Pharma Corporation Production method for protein-containing composition
DE3927111C3 (de) * 1989-08-17 1994-09-01 Biotest Pharma Gmbh Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oderIgA-haltiger Immunglobulinpräparate
JP3145696B2 (ja) * 1990-10-05 2001-03-12 日本ケミカルリサーチ株式会社 分泌型免疫グロブリンａ製剤の製造法
US5110910A (en) * 1991-03-25 1992-05-05 Miles Inc. Virucidal euglobulin precipitation
DE4431833C1 (de) * 1994-09-07 1995-05-18 Blutspendedienst Der Drk Lande Verfahren zur Herstellung eines AHF-Konzentrates
UA64742C2 (uk) * 1997-12-24 2004-03-15 Альфа Терапевтик Корпорейшн СПОСІБ ОДЕРЖАННЯ РОЗЧИНУ <font face="Symbol">g</font>-ГЛОБУЛІНУ, ПРИЗНАЧЕНОГО ДЛЯ ВНУТРІШНЬОВЕННОГО ВВЕДЕННЯ, І ПРОДУКТ, ЩО ОДЕРЖУЄТЬСЯ У ЦЕЙ СПОСІБ (ВАРІАНТИ)

Also Published As

Publication number Publication date
KR20020010921A (ko) 2002-02-06
EP1185290A4 (en) 2005-08-31
CZ20014456A3 (cs) 2002-05-15
IL146433A0 (en) 2002-07-25
CA2375560A1 (en) 2000-12-21
AU5722400A (en) 2001-01-02
WO2000076534A1 (en) 2000-12-21
ZA200110168B (en) 2002-08-26
AU756071B2 (en) 2003-01-02
CN1358100A (zh) 2002-07-10
EP1185290A1 (en) 2002-03-13
PL352910A1 (en) 2003-09-22
HK1048252A1 (zh) 2003-03-28
JP2003501480A (ja) 2003-01-14

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 (VIII), 11 E 13 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.