BR0008402A - Uses of doxepine, doxepine hydrochloride or a metabolite of doxepine or doxepine hydrochloride, and of a tca, pharmaceutical composition, methods to provide an analgesic treatment, and to improve deep localized or internal pain - Google Patents
Uses of doxepine, doxepine hydrochloride or a metabolite of doxepine or doxepine hydrochloride, and of a tca, pharmaceutical composition, methods to provide an analgesic treatment, and to improve deep localized or internal painInfo
- Publication number
- BR0008402A BR0008402A BR0008402-6A BR0008402A BR0008402A BR 0008402 A BR0008402 A BR 0008402A BR 0008402 A BR0008402 A BR 0008402A BR 0008402 A BR0008402 A BR 0008402A
- Authority
- BR
- Brazil
- Prior art keywords
- doxepine
- hydrochloride
- tca
- metabolite
- pharmaceutical composition
- Prior art date
Links
- ODQWQRRAPPTVAG-BOPFTXTBSA-N cis-doxepin Chemical compound C1OC2=CC=CC=C2C(=C/CCN(C)C)\C2=CC=CC=C21 ODQWQRRAPPTVAG-BOPFTXTBSA-N 0.000 title abstract 8
- 229960005426 doxepin Drugs 0.000 title abstract 6
- MHNSPTUQQIYJOT-CULRIWENSA-N (3z)-3-(6h-benzo[c][1]benzoxepin-11-ylidene)-n,n-dimethylpropan-1-amine;hydrochloride Chemical compound Cl.C1OC2=CC=CC=C2C(=C/CCN(C)C)\C2=CC=CC=C21 MHNSPTUQQIYJOT-CULRIWENSA-N 0.000 title abstract 4
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
"USOS DE DOXEPINA, CLORIDRETO DE DOXEPINA OU UM METABóLITO DE DOXEPINA OU CLORIDRETO DE DOXEPINA, E DE UM TCA, COMPOSIçãO FARMACêUTICA, MéTODOS PARA PROVER UM TRATAMENTO ANALGéSICO, E PARA MELHORAR A DOR PROFUNDA LOCALIZADA OU INTERNA". Uso da doxepina, cloridreto de doxepina ou um metabólico da doxepina ou cloridreto de doxepina para a manufatura de um medicamento para melhorar a dor em um indivíduo."USES OF DOXEPINE, DOXEPINE CHLORIDIDE OR A DOXEPINE METABOLITE OR DOXEPINE CHLORIDIDE, AND OF A TCA, PHARMACEUTICAL COMPOSITION, METHODS TO PROVIDE ANALGESIC TREATMENT, AND TO IMPROVE LOCALIZED DEEP PAIN". Use of doxepine, doxepine hydrochloride or a doxepine metabolic or doxepine hydrochloride for the manufacture of a drug to improve pain in an individual.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9904163.4A GB9904163D0 (en) | 1999-02-23 | 1999-02-23 | Pharmaceutical compositions |
| PCT/GB2000/000640 WO2000050025A1 (en) | 1999-02-23 | 2000-02-23 | Topic tricyclic antidepressants as analgesics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0008402A true BR0008402A (en) | 2002-01-29 |
Family
ID=10848352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0008402-6A BR0008402A (en) | 1999-02-23 | 2000-02-23 | Uses of doxepine, doxepine hydrochloride or a metabolite of doxepine or doxepine hydrochloride, and of a tca, pharmaceutical composition, methods to provide an analgesic treatment, and to improve deep localized or internal pain |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1152754A1 (en) |
| JP (1) | JP2002537330A (en) |
| AU (1) | AU2682500A (en) |
| BR (1) | BR0008402A (en) |
| CA (1) | CA2362564A1 (en) |
| GB (1) | GB9904163D0 (en) |
| HU (1) | HUP0200061A2 (en) |
| IL (1) | IL144511A0 (en) |
| WO (1) | WO2000050025A1 (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6284797B1 (en) * | 1999-04-12 | 2001-09-04 | Donald A. Rhodes | Topical treatment of pain and to promote healing |
| CA2449987C (en) * | 2001-06-07 | 2015-11-03 | Christine N. Sang | Treatment of central neuropathic pain |
| US6638981B2 (en) * | 2001-08-17 | 2003-10-28 | Epicept Corporation | Topical compositions and methods for treating pain |
| CN102205127A (en) | 2002-12-18 | 2011-10-05 | 阿尔乔医疗公司 | Administration of capsaicinoids |
| SI1587506T1 (en) | 2002-12-18 | 2009-04-30 | Algorx 101 Interchange Plaza S | Administration of capsaicinoids |
| US20050176809A1 (en) * | 2004-02-05 | 2005-08-11 | Rodlen Laboratories, Inc. | Method and compositions for treatment of painful disorders |
| WO2007049825A1 (en) * | 2005-10-28 | 2007-05-03 | Kyushu University, National University Corporation | P2x4 receptor antagonist |
| US20100179215A1 (en) | 2006-05-19 | 2010-07-15 | Somaxon Pharmaceuticals, Inc. | Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders |
| WO2007136845A2 (en) | 2006-05-19 | 2007-11-29 | Somaxon Pharmaceuticals, Inc. | Low-dose doxepin for treatment of sleep disorders in elderly patients |
| US20100179214A1 (en) | 2006-05-19 | 2010-07-15 | Somaxon Pharmaceuticals, Inc. | Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders |
| JP2009537553A (en) | 2006-05-19 | 2009-10-29 | ソマクソン ファーマシューティカルズ インコーポレイテッド | Use of low-dose doxepin to improve sleep |
| WO2007136741A2 (en) * | 2006-05-19 | 2007-11-29 | Somaxon Pharmaceuticals, Inc. | N-desmethyl-doxepin and methods of using the same to treat sleep disorders |
| CA2693992C (en) | 2006-07-20 | 2017-01-31 | Somaxon Pharmaceuticals, Inc. | Methods of improving the pharmacokinetics of doxepin |
| US20100105614A1 (en) | 2006-10-25 | 2010-04-29 | Somaxon Pharmaceuticals, Inc. | Ultra low dose doxepin and methods of using the same to treat sleep disorders |
| US20110077200A1 (en) | 2006-12-06 | 2011-03-31 | Somaxon Pharmaceuticals, Inc. | Combination therapy using low-dose doxepin for the improvement of sleep |
| WO2008128115A2 (en) | 2007-04-13 | 2008-10-23 | Somaxon Pharmaceuticals, Inc. | Low-dose doxepin formulations |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5008289A (en) * | 1988-12-02 | 1991-04-16 | Galenpharma, Inc. | Composition for treating nasal disorders and headaches |
| US6197830B1 (en) * | 1995-09-22 | 2001-03-06 | Bruce M. Frome | Method for achieving relief from sympathetically mediated pain |
| US6211171B1 (en) * | 1998-05-19 | 2001-04-03 | Dalhousie University | Use of antidepressants for local analgesia |
-
1999
- 1999-02-23 GB GBGB9904163.4A patent/GB9904163D0/en not_active Ceased
-
2000
- 2000-02-23 HU HU0200061A patent/HUP0200061A2/en unknown
- 2000-02-23 JP JP2000600637A patent/JP2002537330A/en not_active Withdrawn
- 2000-02-23 IL IL14451100A patent/IL144511A0/en unknown
- 2000-02-23 EP EP00905198A patent/EP1152754A1/en not_active Withdrawn
- 2000-02-23 WO PCT/GB2000/000640 patent/WO2000050025A1/en not_active Ceased
- 2000-02-23 CA CA002362564A patent/CA2362564A1/en not_active Abandoned
- 2000-02-23 BR BR0008402-6A patent/BR0008402A/en not_active Application Discontinuation
- 2000-02-23 AU AU26825/00A patent/AU2682500A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| GB9904163D0 (en) | 1999-04-14 |
| EP1152754A1 (en) | 2001-11-14 |
| WO2000050025A1 (en) | 2000-08-31 |
| CA2362564A1 (en) | 2000-08-31 |
| JP2002537330A (en) | 2002-11-05 |
| AU2682500A (en) | 2000-09-14 |
| HUP0200061A2 (en) | 2002-06-29 |
| IL144511A0 (en) | 2002-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/00 (2006.01), A61K 31/165 (2006.01), A61P |