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BR0008454A - Composição sinergìstica anti-tumoral - Google Patents

Composição sinergìstica anti-tumoral

Info

Publication number
BR0008454A
BR0008454A BR0008454-9A BR0008454A BR0008454A BR 0008454 A BR0008454 A BR 0008454A BR 0008454 A BR0008454 A BR 0008454A BR 0008454 A BR0008454 A BR 0008454A
Authority
BR
Brazil
Prior art keywords
treatment
tumor composition
metansulfonyl
demethoxy
daunorubicin
Prior art date
Application number
BR0008454-9A
Other languages
English (en)
Inventor
Cristina Geroni
Michele Caruso
Antonino Suarato
Marina Ripamonti
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of BR0008454A publication Critical patent/BR0008454A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPOSIçãO SINERGìSTICA ANTI-TUMORAL". São fornecidos o uso combinado de 4-demetoxi-3'-deamino-3'-aziridinil-4'metansulfonil daunorubicina ou 4-demetoxi-N,N-bis(2-cloroctil)-4'-metansulfonil daunorubicina e de um composto anti-neoplásico anti-mitótico e/ou um derivado de platina no tratamento de tumores, assim como na prevenção ou tratamento de metástase ou no tratamento de tumores pela inibição da angiogênese.
BR0008454-9A 1999-02-25 2000-01-31 Composição sinergìstica anti-tumoral BR0008454A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9904386.1A GB9904386D0 (en) 1999-02-25 1999-02-25 Antitumour synergistic composition
PCT/EP2000/000746 WO2000050033A2 (en) 1999-02-25 2000-01-31 Anti-tumor synergetic composition

Publications (1)

Publication Number Publication Date
BR0008454A true BR0008454A (pt) 2002-01-29

Family

ID=10848513

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008454-9A BR0008454A (pt) 1999-02-25 2000-01-31 Composição sinergìstica anti-tumoral

Country Status (17)

Country Link
US (1) US6593303B1 (pt)
EP (1) EP1169035B1 (pt)
JP (1) JP2002537334A (pt)
KR (1) KR20010102402A (pt)
CN (1) CN1341020A (pt)
AR (1) AR022719A1 (pt)
AT (1) ATE286391T1 (pt)
AU (1) AU774393B2 (pt)
BR (1) BR0008454A (pt)
CA (1) CA2361828A1 (pt)
DE (1) DE60017250D1 (pt)
GB (1) GB9904386D0 (pt)
HK (1) HK1042249A1 (pt)
MY (1) MY125222A (pt)
NZ (1) NZ513352A (pt)
WO (1) WO2000050033A2 (pt)
ZA (1) ZA200106210B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9916882D0 (en) * 1999-07-19 1999-09-22 Pharmacia & Upjohn Spa Antitumor synergistic composition
CZ20022216A3 (cs) * 2001-07-02 2003-05-14 Warner-Lambert Company Kombinační chemoterapie
CN101163729B (zh) 2005-04-22 2013-04-10 三菱化学株式会社 来自生物质资源的聚酯及其制造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177263A (en) * 1972-02-28 1979-12-04 Research Corporation Anti-animal tumor method
JPH02157291A (ja) * 1988-12-07 1990-06-18 Morishita Pharmaceut Co Ltd アントラサイクリン系抗生物質のｎ−ホルミルアミノ酸複合体およびその白金錯体組成物
GB9114549D0 (en) * 1991-07-05 1991-08-21 Erba Carlo Spa Mono and bis alkylamino-anthracyclines
US5294538A (en) 1991-11-18 1994-03-15 Cold Spring Harbor Labs. Method of screening for antimitotic compounds using the CDC25 tyrosine phosphatase
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives
JPH07188034A (ja) * 1993-12-28 1995-07-25 Nisshin Flour Milling Co Ltd エンドセリン変換酵素阻害剤
US5716988A (en) * 1994-08-08 1998-02-10 Debiopharm S.A. Pharmaceutically stable preparation of oxaliplatinum
US5919816A (en) * 1994-11-14 1999-07-06 Bionumerik Pharmaceuticals, Inc. Formulations and methods of reducing toxicity of antineoplastic agents
EP0914116B1 (en) * 1996-05-22 2000-10-11 Protarga Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
DE69919695T2 (de) * 1998-06-05 2005-09-15 Board of Regents, The University of Texas System, Austin Texaphyrin-konjugate und ihre anwendiung

Also Published As

Publication number Publication date
AU774393B2 (en) 2004-06-24
EP1169035B1 (en) 2005-01-05
GB9904386D0 (en) 1999-04-21
WO2000050033A3 (en) 2000-12-21
HK1042249A1 (zh) 2002-08-09
JP2002537334A (ja) 2002-11-05
EP1169035A2 (en) 2002-01-09
KR20010102402A (ko) 2001-11-15
ATE286391T1 (de) 2005-01-15
DE60017250D1 (de) 2005-02-10
CA2361828A1 (en) 2000-08-31
NZ513352A (en) 2003-08-29
MY125222A (en) 2006-07-31
WO2000050033A2 (en) 2000-08-31
US6593303B1 (en) 2003-07-15
AU2668100A (en) 2000-09-14
CN1341020A (zh) 2002-03-20
AR022719A1 (es) 2002-09-04
ZA200106210B (en) 2002-10-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 NA RPI2003 DE 26/05/2009.