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BR0004530A - Processo para manufaturamento de preparações oftálmicas tópicas sem efeitos sistêmicos - Google Patents

Processo para manufaturamento de preparações oftálmicas tópicas sem efeitos sistêmicos

Info

Publication number
BR0004530A
BR0004530A BR0004530-6A BR0004530A BR0004530A BR 0004530 A BR0004530 A BR 0004530A BR 0004530 A BR0004530 A BR 0004530A BR 0004530 A BR0004530 A BR 0004530A
Authority
BR
Brazil
Prior art keywords
topical
preparations
systemic
effects
systemic effects
Prior art date
Application number
BR0004530-6A
Other languages
English (en)
Inventor
Bakulesh Mafatlal Khamar
Original Assignee
Bakulesh Mafatlal Khamar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bakulesh Mafatlal Khamar filed Critical Bakulesh Mafatlal Khamar
Publication of BR0004530A publication Critical patent/BR0004530A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção para: <B>"PROCESSO PARA MANUFATURAMENTO DE PREPARAçõES OFTáLMICAS TóPICAS SEM EFEITOS SISTêMICOS"<D>. Para tratamento de doenças do olho, vários tipos de medicações são usadas. Elas são usadas na forma de preparações tópicas ou na forma de preparações sistêmicas para serem tomadas oralmente ou parenteralmente. De preparações tópicas, algumas são para uso tópico somente, por exemplo., framicetina, neomicina, loteprednol ebanoato, etc. Contudo, a grande maioria de drogas oftálmicas tópicas são para uso sistêmico também, por exemplo, Ciprofloxacina, Gentamicina, Timolol, Clonidina, Dexametasona, Betametasona, Carbachol, etc. Algumas destas drogas quando usadas topicamente são também verificadas apresentarem efeitos sistêmicos e se elas são de natureza séria, limitam o uso desta droga, por exemplo., efeitos cardio-pulmonares de ß-bloqueadores similares a timolol. Secura da boca, rubor, febre, taquicardia, retenção urinária, convulsão, irritabilidade com atropina. Hiper-tensão com fenilefina. Salivamento aumentado, náusea, vómito, diarréia, cólicas estomacais, secreções bronquiais, constrição bronquial, asma, bradicardia, parestesia com mióticos, Hipotensão com clonidina. Boca seca, fadiga e sonolência com apraclonidina e brimonidina.
BR0004530-6A 1999-02-03 2000-02-02 Processo para manufaturamento de preparações oftálmicas tópicas sem efeitos sistêmicos BR0004530A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN90BO1999 IN185228B (pt) 1999-02-03 1999-02-03
PCT/IN2000/000008 WO2000049990A2 (en) 1999-02-03 2000-02-02 The process for manufacturing topical ophthalmic preparations without systemic effects

Publications (1)

Publication Number Publication Date
BR0004530A true BR0004530A (pt) 2001-04-03

Family

ID=11077485

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0004530-6A BR0004530A (pt) 1999-02-03 2000-02-02 Processo para manufaturamento de preparações oftálmicas tópicas sem efeitos sistêmicos

Country Status (11)

Country Link
EP (1) EP1139970A2 (pt)
AP (1) AP2000001977A0 (pt)
AU (1) AU4429100A (pt)
BR (1) BR0004530A (pt)
CA (1) CA2326690A1 (pt)
EA (1) EA200000918A1 (pt)
ID (1) ID28121A (pt)
IL (1) IL138824A0 (pt)
IN (1) IN185228B (pt)
WO (1) WO2000049990A2 (pt)
ZA (1) ZA200006252B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005220199B2 (en) * 2000-07-14 2007-03-08 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US8858961B2 (en) 2000-07-14 2014-10-14 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
RU2311928C2 (ru) * 2000-07-14 2007-12-10 Аллерган Инк. Композиции, содержащие альфа-2-адренергические агонисты
DE10132876A1 (de) * 2001-07-06 2003-01-30 Medproject Pharma Entwicklungs Zweiphasige, tropfbare Hydrogele zur Anwendung am Auge
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
CN104490884A (zh) 2004-05-25 2015-04-08 桑斯罗萨医药发展公司 治疗或预防炎症性皮肤疾病的化合物、制剂及方法
EP2329849B1 (en) 2009-11-18 2015-04-29 Galderma Research & Development Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
FR2977493B1 (fr) 2011-07-05 2014-02-14 Galderma Res & Dev Nouvelle composition anesthesique stable pour la reduction des reactions cutanees
CA2901280A1 (en) * 2013-02-15 2014-08-21 Allergan, Inc. Sustained drug delivery implant
WO2014150899A1 (en) * 2013-03-15 2014-09-25 Chapin Matthew J Topical ophthalmic formulations for treating migraine
US9421199B2 (en) 2014-06-24 2016-08-23 Sydnexis, Inc. Ophthalmic composition
WO2016172712A2 (en) 2015-04-23 2016-10-27 Sydnexis, Inc. Ophthalmic composition
EP3302426A4 (en) 2015-05-29 2018-12-05 Sydnexis, Inc. D2o stabilized pharmaceutical formulations
GB202110420D0 (en) * 2021-07-20 2021-09-01 Rosemont Pharmaceuticals Ltd Liquid pharmaceutical composition of clonidine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6056684B2 (ja) * 1977-11-07 1985-12-11 東興薬品工業株式会社 点眼剤
DD294174A5 (de) * 1990-05-04 1991-09-26 Sigrid Keipert Ophthalmika mit retardwirkung und ein neues verfahren zu ihrer herstellung
FR2678832B1 (fr) * 1991-07-10 1995-03-17 Europhta Sa Laboratoire Nouvelles compositions ophtalmiques a resorption amelioree et leurs procedes de preparation.
FR2679773A1 (fr) * 1991-07-30 1993-02-05 Merck Sharp & Dohme Preparation ophtalmique contenant un agent osmotique acceptable antimicrobien.
DE19614823A1 (de) * 1996-04-15 1997-10-16 Mann Gerhard Chem Pharm Fab Ophthalmische Zusammensetzung mit verlängerter Verweilzeit am Auge

Also Published As

Publication number Publication date
IN185228B (pt) 2000-12-09
EP1139970A2 (en) 2001-10-10
CA2326690A1 (en) 2000-08-31
WO2000049990A2 (en) 2000-08-31
ZA200006252B (en) 2001-11-29
AU4429100A (en) 2000-09-14
AP2000001977A0 (en) 2000-12-31
ID28121A (id) 2001-05-03
EA200000918A1 (ru) 2001-10-22
IL138824A0 (en) 2001-10-31
WO2000049990A3 (en) 2001-07-26

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]