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BG63276B1 - Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване - Google Patents

Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване Download PDF

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Publication number
BG63276B1
BG63276B1 BG101226A BG10122697A BG63276B1 BG 63276 B1 BG63276 B1 BG 63276B1 BG 101226 A BG101226 A BG 101226A BG 10122697 A BG10122697 A BG 10122697A BG 63276 B1 BG63276 B1 BG 63276B1
Authority
BG
Bulgaria
Prior art keywords
palidipine
asp
protein
seq
amino acid
Prior art date
Application number
BG101226A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG101226A (bg
Inventor
Christiane Noeske-Jungblut
Andreas Becker
Bernard Haendler
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG101226A publication Critical patent/BG101226A/xx
Publication of BG63276B1 publication Critical patent/BG63276B1/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BG101226A 1994-09-12 1997-02-12 Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване BG63276B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94250224 1994-09-12
PCT/EP1995/003573 WO1996008563A1 (fr) 1994-09-12 1995-09-11 Procede de preparation d'un inhibiteur modifie de l'agregation plaquettaire induite par le collagene: la pallidipine

Publications (2)

Publication Number Publication Date
BG101226A BG101226A (bg) 1998-10-30
BG63276B1 true BG63276B1 (bg) 2001-08-31

Family

ID=8217517

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101226A BG63276B1 (bg) 1994-09-12 1997-02-12 Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване

Country Status (22)

Country Link
US (1) US5882887A (fr)
EP (1) EP0781334A1 (fr)
JP (1) JPH10505502A (fr)
CN (1) CN1075836C (fr)
AU (1) AU701643B2 (fr)
BG (1) BG63276B1 (fr)
BR (1) BR9508910A (fr)
CA (1) CA2199719A1 (fr)
CZ (1) CZ76297A3 (fr)
FI (1) FI971013A7 (fr)
HU (1) HU222398B1 (fr)
IL (1) IL115272A0 (fr)
MX (1) MX9701720A (fr)
NO (1) NO971110L (fr)
NZ (1) NZ293261A (fr)
PL (1) PL184617B1 (fr)
RO (1) RO117971B1 (fr)
RU (1) RU2186110C2 (fr)
SI (1) SI9520093A (fr)
SK (1) SK29297A3 (fr)
WO (1) WO1996008563A1 (fr)
ZA (1) ZA957649B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL200384B1 (pl) * 1999-03-18 2008-12-31 Merck Patent Gmbh Polipeptyd blokujący adhezję płytek krwi, sposób jego otrzymywania, zastosowanie i zawierający go preparat farmaceutyczny
EP1831395A1 (fr) * 2004-12-28 2007-09-12 Ares Trading S.A. Compositions et procedes de traitement de la schizophrenie et de troubles associes
US7691839B2 (en) 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
TWI391143B (zh) * 2005-11-04 2013-04-01 Otsuka Pharma Co Ltd 血小板凝集抑制劑組成物
US9617302B2 (en) * 2011-06-14 2017-04-11 National Taiwan University Peptide compounds for inhibition of platelet aggregation
FR2979346B1 (fr) 2011-08-23 2013-09-27 Univ Joseph Fourier Nanocorps anti-vcam-1
EP2812012A1 (fr) 2012-02-07 2014-12-17 Global Bio Therapeutics USA, Inc. Procédé compartimenté d'administration d'acide nucléique et ses compositions et utilisations
NZ705899A (en) 2012-09-07 2018-08-31 Inst Nat Sante Rech Med Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (trem-1) trem-like transcript 1 (tlt-1) and uses thereof
MX378673B (es) 2013-08-08 2025-03-10 Global Bio Therapeutics Inc Dispositivo de sujecion para procedimientos minimamente invasivos y usos del mismo.
FR3058143B1 (fr) 2016-10-27 2021-03-12 Univ Grenoble Alpes Nanocorps anti-tau
EP4340855A1 (fr) 2021-08-13 2024-03-27 Triovance Holding LLC Composition de substitut de peau et ses procédés de production et d'utilisation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03503596A (ja) * 1987-06-24 1991-08-15 ノボ・ノルディスク エー/エス 蛋白質若しくはポリペプチドの調製方法、該ポリペプチドをコードするdna配列、該dna配列およびポリペプチドを有する微生物および該ポリペプチドの薬学的製剤としての利用
RU2128705C1 (ru) * 1991-09-05 1999-04-10 Шеринг Аг Протеин, ингибирующий вызываемую коллагеном агрегацию тромбоцитов млекопитающих, рекомбинантный протеин, ингибирующий вызываемую коллагеном агрегацию тромбоцитов, фрагмент днк, кодирующий рекомбинантный протеин, вектор экспрессии (варианты), штамм культивируемых животных клеток внк - продуцент рекомбинантного протеина (варианты), способ получения рекомбинантного протеина, фармацевтическая композиция
US5756454A (en) * 1991-09-05 1998-05-26 Schering Aktiengesellschaft Collagen-induced platelet aggregation inhibitor
US5705362A (en) * 1992-05-25 1998-01-06 Gist-Brocades, N.V. Modified signal sequences

Also Published As

Publication number Publication date
NO971110L (no) 1997-05-07
PL184617B1 (pl) 2002-11-29
NO971110D0 (no) 1997-03-11
FI971013A0 (fi) 1997-03-11
WO1996008563A1 (fr) 1996-03-21
AU701643B2 (en) 1999-02-04
HUT76972A (hu) 1998-01-28
JPH10505502A (ja) 1998-06-02
HU222398B1 (hu) 2003-06-28
SK29297A3 (en) 1997-10-08
CA2199719A1 (fr) 1996-03-21
CZ76297A3 (cs) 1998-01-14
BR9508910A (pt) 1997-10-28
FI971013A7 (fi) 1997-03-11
EP0781334A1 (fr) 1997-07-02
PL319078A1 (en) 1997-07-21
IL115272A0 (en) 1995-12-31
RU2186110C2 (ru) 2002-07-27
MX9701720A (es) 1997-06-28
SI9520093A (en) 1997-08-31
CN1159828A (zh) 1997-09-17
CN1075836C (zh) 2001-12-05
NZ293261A (en) 1998-11-25
BG101226A (bg) 1998-10-30
US5882887A (en) 1999-03-16
ZA957649B (en) 1996-04-15
RO117971B1 (ro) 2002-11-29
AU3565795A (en) 1996-03-29

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