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BG20349A3 - METHOD FOR THE PREPARATION OF 1(4,4-BIS(P-FLUORO-PHENYL)BUTYL)-4-PIPERIDYL)-2- BENZIMIDAZOLINONE - Google Patents

METHOD FOR THE PREPARATION OF 1(4,4-BIS(P-FLUORO-PHENYL)BUTYL)-4-PIPERIDYL)-2- BENZIMIDAZOLINONE

Info

Publication number
BG20349A3
BG20349A3 BG024007A BG2400772A BG20349A3 BG 20349 A3 BG20349 A3 BG 20349A3 BG 024007 A BG024007 A BG 024007A BG 2400772 A BG2400772 A BG 2400772A BG 20349 A3 BG20349 A3 BG 20349A3
Authority
BG
Bulgaria
Prior art keywords
benzimidazolinone
piperidyl
fluoro
bis
phenyl
Prior art date
Application number
BG024007A
Other languages
Bulgarian (bg)
Inventor
Marscel Janssen
Henri Dhaen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BG20349A3 publication Critical patent/BG20349A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64Acyl halides
    • C07C57/72Acyl halides containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/52Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BG024007A 1971-11-25 1972-10-12 METHOD FOR THE PREPARATION OF 1(4,4-BIS(P-FLUORO-PHENYL)BUTYL)-4-PIPERIDYL)-2- BENZIMIDAZOLINONE BG20349A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9485771A JPS5527915B2 (en) 1971-11-25 1971-11-25

Publications (1)

Publication Number Publication Date
BG20349A3 true BG20349A3 (en) 1975-11-05

Family

ID=14121686

Family Applications (2)

Application Number Title Priority Date Filing Date
BG024007A BG20349A3 (en) 1971-11-25 1972-10-12 METHOD FOR THE PREPARATION OF 1(4,4-BIS(P-FLUORO-PHENYL)BUTYL)-4-PIPERIDYL)-2- BENZIMIDAZOLINONE
BG021601A BG20348A3 (en) 1971-11-25 1972-10-12 METHOD FOR PREPARATION OF 4-SUBSTITUTED 1-(4,4-DIARYL-BUTYL) PIPERIDINES

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG021601A BG20348A3 (en) 1971-11-25 1972-10-12 METHOD FOR PREPARATION OF 4-SUBSTITUTED 1-(4,4-DIARYL-BUTYL) PIPERIDINES

Country Status (14)

Country Link
JP (1) JPS5527915B2 (en)
AR (2) AR198393A1 (en)
BG (2) BG20349A3 (en)
CA (1) CA983503A (en)
CH (1) CH579048A5 (en)
CS (1) CS168014B2 (en)
ES (1) ES408926A1 (en)
FR (1) FR2161007A1 (en)
HU (1) HU165208B (en)
IL (1) IL40917A (en)
NL (1) NL7214913A (en)
RO (2) RO63063A (en)
SU (1) SU462333A3 (en)
YU (1) YU35120B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082755A (en) * 1977-02-14 1978-04-04 Janssen Pharmaceutica N.V. 1-[(Diarylmethyl)aminoalkyl]piperidimes
CN106187863A (en) * 2016-07-15 2016-12-07 湖南中南制药有限责任公司 The preparation method of penfluridol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (en) * 1962-06-13

Also Published As

Publication number Publication date
BG20348A3 (en) 1975-11-05
RO63063A (en) 1978-07-15
IL40917A0 (en) 1973-01-30
IL40917A (en) 1976-10-31
JPS4860092A (en) 1973-08-23
CS168014B2 (en) 1976-05-28
AR198393A1 (en) 1974-06-21
CH579048A5 (en) 1976-08-31
RO62760A (en) 1978-02-15
YU35120B (en) 1980-09-25
HU165208B (en) 1974-07-27
JPS5527915B2 (en) 1980-07-24
FR2161007B1 (en) 1976-03-05
NL7214913A (en) 1973-05-29
CA983503A (en) 1976-02-10
AR199497A1 (en) 1974-09-09
FR2161007A1 (en) 1973-07-06
ES408926A1 (en) 1976-03-01
YU291672A (en) 1980-03-15
SU462333A3 (en) 1975-02-28

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