BG103917A - Разтворими дозирани форми от сертралин включени вжелатинови капсули - Google Patents

Разтворими дозирани форми от сертралин включени вжелатинови капсули Download PDF

Info

Publication number: BG103917A
Authority: BG; Bulgaria
Prior art keywords: sertraline; dosage form; mga; oil; carrier
Prior art date: 1997-07-01

Application number

BG103917A

Other languages

Bulgarian (bg)

English (en)

Inventor

William Curatolo

Ravi Shanker

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-01

Filing date

1999-11-23

Publication date

2000-07-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21971076&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG103917(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-11-23 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2000-07-31 Publication of BG103917A publication Critical patent/BG103917A/bg

Links

VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 title claims description 222
229960002073 sertraline Drugs 0.000 title claims description 213
229920000159 gelatin Polymers 0.000 title description 14
235000019322 gelatine Nutrition 0.000 title description 14
239000001828 Gelatine Substances 0.000 title 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 28
238000001556 precipitation Methods 0.000 claims abstract description 27
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims abstract description 22
239000002552 dosage form Substances 0.000 claims description 60
239000007903 gelatin capsule Substances 0.000 claims description 29
150000003839 salts Chemical class 0.000 claims description 24
239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims description 21
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 21
229940068968 polysorbate 80 Drugs 0.000 claims description 21
229920000053 polysorbate 80 Polymers 0.000 claims description 21
239000000203 mixture Substances 0.000 claims description 19
239000003921 oil Substances 0.000 claims description 19
235000019198 oils Nutrition 0.000 claims description 19
244000124209 Crocus sativus Species 0.000 claims description 16
235000015655 Crocus sativus Nutrition 0.000 claims description 16
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235000013974 saffron Nutrition 0.000 claims description 16
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WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 12
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238000000034 method Methods 0.000 claims description 10
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UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 7
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WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims description 6
LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims description 6
QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims description 6
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GLQPTZAAUROJMO-UHFFFAOYSA-N 4-(3,4-dimethoxyphenyl)benzaldehyde Chemical compound C1=C(OC)C(OC)=CC=C1C1=CC=C(C=O)C=C1 GLQPTZAAUROJMO-UHFFFAOYSA-N 0.000 description 6
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LDVVMCZRFWMZSG-UHFFFAOYSA-N captan Chemical compound C1C=CCC2C(=O)N(SC(Cl)(Cl)Cl)C(=O)C21 LDVVMCZRFWMZSG-UHFFFAOYSA-N 0.000 description 5
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OVYMWJFNQQOJBU-UHFFFAOYSA-N 1-octanoyloxypropan-2-yl octanoate Chemical compound CCCCCCCC(=O)OCC(C)OC(=O)CCCCCCC OVYMWJFNQQOJBU-UHFFFAOYSA-N 0.000 description 3
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238000011160 research Methods 0.000 description 1
238000004366 reverse phase liquid chromatography Methods 0.000 description 1
239000012047 saturated solution Substances 0.000 description 1
230000002269 spontaneous effect Effects 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
208000011117 substance-related disease Diseases 0.000 description 1
230000001629 suppression Effects 0.000 description 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
238000002627 tracheal intubation Methods 0.000 description 1
125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 description 1
PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 description 1
229940117972 triolein Drugs 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
229940046009 vitamin E Drugs 0.000 description 1
235000019165 vitamin E Nutrition 0.000 description 1
239000011709 vitamin E Substances 0.000 description 1
230000008673 vomiting Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Obesity (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Addiction (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

BG103917A 1997-07-01 1999-11-23 Разтворими дозирани форми от сертралин включени вжелатинови капсули BG103917A (bg)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5140197P	1997-07-01	1997-07-01
PCT/IB1998/000936 WO1999001113A1 (en)	1997-07-01	1998-06-16	Gelatine encapsulated solution dosage forms of sertraline

Publications (1)

Publication Number	Publication Date
BG103917A true BG103917A (bg)	2000-07-31

Family

ID=21971076

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG103917A BG103917A (bg)	1997-07-01	1999-11-23	Разтворими дозирани форми от сертралин включени вжелатинови капсули

Country Status (40)

Country	Link
EP (1)	EP0980241B1 (is)
JP (1)	JP3585245B2 (is)
KR (1)	KR100371730B1 (is)
CN (1)	CN1261792A (is)
AP (1)	AP945A (is)
AR (1)	AR015916A1 (is)
AT (1)	ATE256457T1 (is)
AU (1)	AU724635B2 (is)
BG (1)	BG103917A (is)
BR (1)	BR9809712A (is)
CA (1)	CA2290973C (is)
CO (1)	CO4940405A1 (is)
DE (1)	DE69820608T2 (is)
DK (1)	DK0980241T3 (is)
DZ (1)	DZ2544A1 (is)
EA (1)	EA001905B1 (is)
ES (1)	ES2210760T3 (is)
GT (1)	GT199800090A (is)
HR (1)	HRP980378B1 (is)
HU (1)	HUP0002250A3 (is)
ID (1)	ID24673A (is)
IL (1)	IL133075A0 (is)
IS (1)	IS5266A (is)
MA (1)	MA24586A1 (is)
MY (1)	MY119728A (is)
NO (1)	NO996492L (is)
NZ (1)	NZ501252A (is)
OA (1)	OA11246A (is)
PA (1)	PA8454001A1 (is)
PE (1)	PE97299A1 (is)
PL (1)	PL337807A1 (is)
PT (1)	PT980241E (is)
SK (1)	SK282914B6 (is)
TN (1)	TNSN98123A1 (is)
TR (1)	TR199903282T2 (is)
TW (1)	TW382597B (is)
UA (1)	UA68350C2 (is)
UY (1)	UY25070A1 (is)
WO (1)	WO1999001113A1 (is)
ZA (1)	ZA985709B (is)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL348119A1 (en) *	1998-10-13	2002-05-06	Pfizer Prod Inc	Sertraline oral concentrate
US6727283B2 (en)	1998-10-13	2004-04-27	Pfizer Inc.	Sertraline oral concentrate
DE60026146T2 (de)	1999-09-03	2006-08-17	Apbi Holdings, Llc	Verwendung von Dapoxetin, A selektiver Serotonin Aufnahme Inhibitor mit schnellem Wirkungseintritt, zur Behandlung von sexueller Disfunktion
CA2420535A1 (en)	2000-08-30	2002-03-07	Mary Tanya Am Ende	Sustained release formulations for growth hormone secretagogues
EP1375659A1 (en) *	2002-06-18	2004-01-02	Laboratorio di Diagnostica Moleculare	Soluble capsules containing stock mixtures for easy preparation of chemical or biological solutions
EP1556000A1 (en) *	2002-10-31	2005-07-27	Alza Corporation	Pharmaceutical formulation providing an increased biovailability of hydrophobic drugs
WO2016020936A2 (en) *	2014-07-21	2016-02-11	Patel Jayendrakumar Dasharathlal	A novel oral gastroretentive pharmaceutical dosage form
CN108014087A (zh) *	2017-12-27	2018-05-11	江苏联环药业股份有限公司	一种盐酸舍曲林胶囊的制备方法
GB2630572A (en)	2023-05-29	2024-12-04	Novumgen Ltd	An orally disintegrating tablet of sertraline and its process of preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69525847T2 (de) *	1994-09-19	2002-09-05	Dupont Pharmaceuticals Co., Wilmington	Zusammensetzungen von opioid antagonisten mit selektiven serotonin-aufnahme inhibitoren, zur behandlung von alkoholismus und alkohoabhängigkeit
DE69626916T2 (de) *	1995-07-17	2003-10-09	Pfizer Inc., New York	Sertralin zur Behandlung von Post-Myocard-Infarkt-Patienten

1998
- 1998-06-16 PT PT98923021T patent/PT980241E/pt unknown
- 1998-06-16 SK SK1805-99A patent/SK282914B6/sk unknown
- 1998-06-16 DK DK98923021T patent/DK0980241T3/da active
- 1998-06-16 EA EA199900963A patent/EA001905B1/ru not_active IP Right Cessation
- 1998-06-16 KR KR10-1999-7011596A patent/KR100371730B1/ko not_active Expired - Fee Related
- 1998-06-16 PL PL98337807A patent/PL337807A1/xx unknown
- 1998-06-16 TR TR1999/03282T patent/TR199903282T2/xx unknown
- 1998-06-16 AU AU75450/98A patent/AU724635B2/en not_active Ceased
- 1998-06-16 CA CA002290973A patent/CA2290973C/en not_active Expired - Fee Related
- 1998-06-16 CN CN98806765A patent/CN1261792A/zh active Pending
- 1998-06-16 ID IDW991697A patent/ID24673A/id unknown
- 1998-06-16 HU HU0002250A patent/HUP0002250A3/hu unknown
- 1998-06-16 UA UA99116393A patent/UA68350C2/uk unknown
- 1998-06-16 AT AT98923021T patent/ATE256457T1/de not_active IP Right Cessation
- 1998-06-16 ES ES98923021T patent/ES2210760T3/es not_active Expired - Lifetime
- 1998-06-16 DE DE69820608T patent/DE69820608T2/de not_active Expired - Fee Related
- 1998-06-16 BR BR9809712-1A patent/BR9809712A/pt not_active Application Discontinuation
- 1998-06-16 JP JP50677699A patent/JP3585245B2/ja not_active Expired - Fee Related
- 1998-06-16 IL IL13307598A patent/IL133075A0/xx unknown
- 1998-06-16 WO PCT/IB1998/000936 patent/WO1999001113A1/en not_active Ceased
- 1998-06-16 EP EP98923021A patent/EP0980241B1/en not_active Expired - Lifetime
- 1998-06-16 NZ NZ501252A patent/NZ501252A/en unknown
- 1998-06-19 PA PA19988454001A patent/PA8454001A1/es unknown
- 1998-06-25 AP APAP/P/1998/001279A patent/AP945A/en active
- 1998-06-25 TW TW087110254A patent/TW382597B/zh not_active IP Right Cessation
- 1998-06-26 PE PE1998000575A patent/PE97299A1/es not_active Application Discontinuation
- 1998-06-29 GT GT199800090A patent/GT199800090A/es unknown
- 1998-06-29 MY MYPI98002949A patent/MY119728A/en unknown
- 1998-06-29 AR ARP980103145A patent/AR015916A1/es not_active Application Discontinuation
- 1998-06-29 UY UY25070A patent/UY25070A1/es not_active IP Right Cessation
- 1998-06-30 ZA ZA9805709A patent/ZA985709B/xx unknown
- 1998-06-30 DZ DZ980154A patent/DZ2544A1/xx active
- 1998-06-30 TN TNTNSN98123A patent/TNSN98123A1/fr unknown
- 1998-06-30 MA MA25145A patent/MA24586A1/fr unknown
- 1998-07-01 CO CO98037136A patent/CO4940405A1/es unknown
- 1998-07-01 HR HR980378A patent/HRP980378B1/xx not_active IP Right Cessation
1999
- 1999-11-23 IS IS5266A patent/IS5266A/is unknown
- 1999-11-23 BG BG103917A patent/BG103917A/bg unknown
- 1999-12-23 OA OA9900306A patent/OA11246A/en unknown
- 1999-12-27 NO NO996492A patent/NO996492L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR20010013588A (ko)	2001-02-26
MA24586A1 (fr)	1998-12-31
OA11246A (en)	2002-11-19
EP0980241A1 (en)	2000-02-23
NO996492L (no)	2000-02-29
HRP980378B1 (en)	2001-12-31
PE97299A1 (es)	1999-10-13
IL133075A0 (en)	2001-03-19
HUP0002250A2 (hu)	2000-12-28
UA68350C2 (en)	2004-08-16
JP2000512316A (ja)	2000-09-19
HRP980378A2 (en)	1999-04-30
PL337807A1 (en)	2000-09-11
TNSN98123A1 (fr)	2005-03-15
EA001905B1 (ru)	2001-10-22
EP0980241B1 (en)	2003-12-17
AP945A (en)	2001-02-28
TR199903282T2 (xx)	2000-08-21
CA2290973A1 (en)	1999-01-14
KR100371730B1 (ko)	2003-02-07
DE69820608D1 (de)	2004-01-29
TW382597B (en)	2000-02-21
HUP0002250A3 (en)	2001-01-29
EA199900963A1 (ru)	2000-08-28
AU724635B2 (en)	2000-09-28
BR9809712A (pt)	2000-07-11
ID24673A (id)	2000-07-27
DZ2544A1 (fr)	2003-02-08
NZ501252A (en)	2004-11-26
AR015916A1 (es)	2001-05-30
ZA985709B (en)	2000-01-10
ES2210760T3 (es)	2004-07-01
PT980241E (pt)	2004-03-31
JP3585245B2 (ja)	2004-11-04
ATE256457T1 (de)	2004-01-15
SK282914B6 (sk)	2003-01-09
NO996492D0 (no)	1999-12-27
DK0980241T3 (da)	2004-04-05
IS5266A (is)	1999-11-23
CO4940405A1 (es)	2000-07-24
CN1261792A (zh)	2000-08-02
AP9801279A0 (en)	1998-06-30
CA2290973C (en)	2003-06-17
PA8454001A1 (es)	2000-05-24
MY119728A (en)	2005-07-29
UY25070A1 (es)	2000-12-29
GT199800090A (es)	1999-12-21
SK180599A3 (en)	2001-01-18
DE69820608T2 (de)	2004-12-23
AU7545098A (en)	1999-01-25
WO1999001113A1 (en)	1999-01-14

Publication	Publication Date	Title
JP2662183B2 (ja)	1997-10-08	サイクロスポリン軟質カプセル剤組成物
US5589455A (en)	1996-12-31	Cyclosporin-containing soft capsule compositions
RU2211047C2 (ru)	2003-08-27	Желатиновые капсулы с твердым покрытием, включающие фармацевтические композиции, практически не содержащие масел
US7115565B2 (en)	2006-10-03	Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
JP2002531515A (ja)	2002-09-24	水に難溶性の薬剤のための自己乳化組成物
ES2326783T3 (es)	2009-10-20	Composiciones de n-benzoilestaurosporina espontaneamente dispersables.
PL188986B1 (pl)	2005-05-31	Preparaty zawierające cyklosporynę w postaci miękkich kapsułek oraz sposób ich wytwarzania
PL188500B1 (pl)	2005-02-28	Preparaty w postaci miękkich kapsułek zawierającecyklosporynę
NZ539046A (en)	2006-11-30	Chemotherapeutic self-emulsifying microemulsion compositions of paclitaxel with improved oral bioavailability
BG103917A (bg)	2000-07-31	Разтворими дозирани форми от сертралин включени вжелатинови капсули
JPH0840936A (ja)	1996-02-13	経口投与薬物のための製剤
CA2529489C (en)	2012-01-03	Transnasal microemulsions containing diazepam
US20030133974A1 (en)	2003-07-17	Encapsulated solution dosage forms of sertraline
JP2973077B2 (ja)	1999-11-08	ビタミンｅ製剤組成物
RU2185188C2 (ru)	2002-07-20	Фармацевтические композиции
MXPA99012099A (en)	2000-09-04	Gelatine encapsulated solution dosage forms of sertraline
HK1028882A (en)	2001-03-09	Gelatine encapsulated solution dosage forms of sertraline
CZ464299A3 (cs)	2000-04-12	Želatinové zapouzdření roztokové dávkovači formy sertralinu
WO2005007069A2 (en)	2005-01-27	Soft gel formulations for saquinavir