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BG102413A - Скъсени форми на хемокин вета-8 - Google Patents

Скъсени форми на хемокин вета-8 Download PDF

Info

Publication number
BG102413A
BG102413A BG102413A BG10241398A BG102413A BG 102413 A BG102413 A BG 102413A BG 102413 A BG102413 A BG 102413A BG 10241398 A BG10241398 A BG 10241398A BG 102413 A BG102413 A BG 102413A
Authority
BG
Bulgaria
Prior art keywords
polypeptide
sequence
cells
polypeptides
skr
Prior art date
Application number
BG102413A
Other languages
Bulgarian (bg)
English (en)
Inventor
John White
Edward Appelbaum
SHANNESSY Daniel O'
James FORNWALD
Kevin O'donnell
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of BG102413A publication Critical patent/BG102413A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
BG102413A 1995-09-29 1998-04-29 Скъсени форми на хемокин вета-8 BG102413A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US451795P 1995-09-29 1995-09-29
PCT/US1996/015592 WO1997012041A1 (fr) 1995-09-29 1996-09-27 FORMES COURTES DE LA CHIMIOKINE β-8

Publications (1)

Publication Number Publication Date
BG102413A true BG102413A (bg) 1999-04-30

Family

ID=21711157

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102413A BG102413A (bg) 1995-09-29 1998-04-29 Скъсени форми на хемокин вета-8

Country Status (16)

Country Link
EP (1) EP0859842A4 (fr)
JP (1) JPH11512610A (fr)
KR (2) KR19990063834A (fr)
CN (2) CN1198186A (fr)
AU (1) AU711573B2 (fr)
BG (1) BG102413A (fr)
BR (1) BR9610671A (fr)
CZ (1) CZ92198A3 (fr)
EA (1) EA199800352A1 (fr)
HU (1) HUP9802699A3 (fr)
NO (1) NO981387L (fr)
NZ (1) NZ320932A (fr)
PL (1) PL326080A1 (fr)
TR (1) TR199800575T1 (fr)
WO (1) WO1997012041A1 (fr)
ZA (1) ZA968204B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6001606A (en) * 1994-03-08 1999-12-14 Human Genome Sciences, Inc. Polynucleotides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) and polypeptides encoded thereby
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
JP2001500382A (ja) * 1996-09-30 2001-01-16 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド 骨髄前駆体阻害因子―１（ｍｐｉｆ―１）、単球コロニー阻害因子（ｍ―ｃｉｆ）、およびマクロファージ阻害因子―４（ｍｉｐ―４）で疾患状態を処置するための治療組成物および方法
KR19990042713A (ko) * 1997-11-27 1999-06-15 허일섭 사람에서 분리한 c 6 베타-케모카인 lkn-1의 cdna 및 재조합 lkn-1의 제조방법
AU2505601A (en) * 1999-11-15 2001-05-30 Wolf-Georg Forssmann Novel use of hcc-2
US20030215460A1 (en) * 2002-05-07 2003-11-20 Schall Thomas J. Methods and compositions for inducing an immune response

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0735818B1 (fr) * 1993-12-22 2004-03-31 Human Genome Sciences, Inc. PROTEINES INFLAMMATOIRES MACROPHAGES MIP-3, MIP-4 ET MIP-1gamma
EP0871672A4 (fr) * 1995-05-05 1999-05-12 Human Genome Sciences Inc Chimiokine beta-8, chimiokine beta-1 et proteine 4 inflammatoire des macrophages d'origine humaine
DK0871664T3 (da) * 1995-10-24 2004-04-26 Smithkline Beecham Corp Mobilisering af bloddannende stamceller ved anvendelse af en chemokin
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10

Also Published As

Publication number Publication date
EP0859842A1 (fr) 1998-08-26
NO981387D0 (no) 1998-03-26
HUP9802699A3 (en) 2000-09-28
AU711573B2 (en) 1999-10-14
CN1405180A (zh) 2003-03-26
NZ320932A (en) 2000-01-28
KR20030096447A (ko) 2003-12-31
AU7379096A (en) 1997-04-17
KR19990063834A (ko) 1999-07-26
JPH11512610A (ja) 1999-11-02
BR9610671A (pt) 1999-07-06
ZA968204B (en) 1997-04-09
WO1997012041A1 (fr) 1997-04-03
NO981387L (no) 1998-05-29
CN1198186A (zh) 1998-11-04
CZ92198A3 (cs) 1998-07-15
PL326080A1 (en) 1998-08-17
TR199800575T1 (en) 1998-06-22
EA199800352A1 (ru) 1998-12-24
HUP9802699A2 (hu) 1999-03-29
EP0859842A4 (fr) 1999-02-24
MX9802380A (es) 1998-08-30

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