BG101126A - The use of muramylpeptide compounds - Google Patents
The use of muramylpeptide compoundsInfo
- Publication number
- BG101126A BG101126A BG101126A BG10112697A BG101126A BG 101126 A BG101126 A BG 101126A BG 101126 A BG101126 A BG 101126A BG 10112697 A BG10112697 A BG 10112697A BG 101126 A BG101126 A BG 101126A
- Authority
- BG
- Bulgaria
- Prior art keywords
- muramylpeptide
- compounds
- prophylaxy
- treatment
- isoglutam
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- PIJXCSUPSNFXNE-QRZOAFCBSA-N N-acetyl-4-(N-acetylglucosaminyl)muramoyl-L-alanyl-D-isoglutamine Chemical compound OC(=O)CC[C@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@@H]1[C@@H](NC(C)=O)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1 PIJXCSUPSNFXNE-QRZOAFCBSA-N 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
The muramylpeptide compounds, and in particular N-acetyl-d-glucosaminyl-(1-4)-N-acetylmuramul-L-alanyl-D-isoglutam in (GMDP) are used for the treatment and prophylaxy of inflammatory dermatological conditions such as psoriasis and in the treatment and prophylaxy of immunodependent diseases of the skin and the mucuous membranes.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9413935A GB9413935D0 (en) | 1994-07-11 | 1994-07-11 | Use of maramyl peptide compounds |
| CN95194573A CN1155245A (en) | 1994-07-11 | 1995-07-10 | Use of muramyl peptide compounds |
| PCT/GB1995/001619 WO1996001645A1 (en) | 1994-07-11 | 1995-07-10 | Use of muramyl peptide compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG101126A true BG101126A (en) | 1997-09-30 |
Family
ID=25743816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG101126A BG101126A (en) | 1994-07-11 | 1997-01-10 | The use of muramylpeptide compounds |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0768888A1 (en) |
| JP (1) | JPH10505580A (en) |
| CN (1) | CN1155245A (en) |
| AU (1) | AU2893595A (en) |
| BG (1) | BG101126A (en) |
| CA (1) | CA2194678A1 (en) |
| CZ (1) | CZ4797A3 (en) |
| GB (1) | GB9413935D0 (en) |
| HU (1) | HUT77290A (en) |
| IL (1) | IL114542A0 (en) |
| SK (1) | SK2697A3 (en) |
| WO (1) | WO1996001645A1 (en) |
| ZA (1) | ZA955763B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1038532A4 (en) * | 1997-04-11 | 2003-08-13 | Oleg Vitallievich Kaljuzhin | Immunomodulator and pharmaceutical compositions with antitumor properties, and a food additive |
| GB9710351D0 (en) * | 1997-05-20 | 1997-07-16 | Scotia Holdings Plc | Glucosamine fatty acids |
| WO1999062537A1 (en) * | 1998-06-04 | 1999-12-09 | The Rockefeller University | Methods and agents for modulating the immune response and inflammation involving monocyte and dendritic cell membrane proteins |
| DE10106852A1 (en) * | 2001-02-14 | 2002-09-05 | T Luger | Anti-inflammatory compounds |
| FR2899466B1 (en) * | 2006-04-07 | 2008-09-26 | Oreal | USE OF C-GLYCOSIDE COMPOUND ACTIVATING AGENT AND REGULATOR OF SKIN IMMUNITY |
| US20120156137A1 (en) | 2006-10-20 | 2012-06-21 | Soo-Youl Kim | Composition for treatment of atopic dermatitis comprising glucosamine and derivatives thereof and a method for treatment of atopic dermatitis using them |
| US8603978B2 (en) * | 2006-12-01 | 2013-12-10 | The United States of America, as represented by the Secretary, Department of Health and Humand Services | Use of muramyl dipeptide (MDP) for treating inflammation |
| FR2933984B1 (en) * | 2008-07-15 | 2013-01-04 | Univ Bourgogne | D, D MURAMYLDIPEPTIDE, DERIVATIVE COMPOUNDS AND USE FOR THE TREATMENT OF ATHEROMOUS PLAQUES |
| US10610564B2 (en) | 2015-02-26 | 2020-04-07 | Stc.Unm | IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy |
| CN108884132B (en) | 2015-12-10 | 2022-10-04 | 巴拉特生物技术国际有限公司 | Muramyl peptide derivatives a compound their synthesis and their use |
| EP3389643B1 (en) | 2015-12-15 | 2023-05-03 | Bharat Biotech International Limited | Novel muramyl peptide derivative compound, synthesis and uses thereof |
| CN116077439A (en) | 2016-04-29 | 2023-05-09 | 西奈山伊坎医学院 | Targeting the innate immune system to induce long-term tolerance and address macrophage accumulation in atherosclerosis |
| IL306006A (en) | 2021-03-19 | 2023-11-01 | Trained Therapeutix Discovery Inc | Compounds for regulating trained immunity, and their methods of use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4357322A (en) * | 1980-07-29 | 1982-11-02 | Syntex (U.S.A.) Inc. | Method of preventing, reducing or inhibiting inflammation |
| US4698330A (en) * | 1983-06-27 | 1987-10-06 | President & Fellows Of Harvard College | Somnogenic compositions and method of use |
| HU205147B (en) * | 1989-06-29 | 1992-03-30 | Sandoz Ag | Process for producing muramyl dipeptide derivative and pharmaceutical compostions comprising same |
| US5506204A (en) * | 1991-11-19 | 1996-04-09 | Peptech (Uk) Limited | Muramyl compounds for treatment of septic shock |
| GB9204354D0 (en) * | 1992-02-28 | 1992-04-08 | Biokine Tech Ltd | Compounds for medicinal use |
| GB9320820D0 (en) * | 1993-10-08 | 1993-12-01 | Biokine Tech Ltd | Compounds for medicinal use |
| GB9326518D0 (en) * | 1993-12-29 | 1994-03-02 | Sandoz Ltd | Organic compounds |
-
1994
- 1994-07-11 GB GB9413935A patent/GB9413935D0/en active Pending
-
1995
- 1995-07-10 JP JP8504191A patent/JPH10505580A/en active Pending
- 1995-07-10 CN CN95194573A patent/CN1155245A/en active Pending
- 1995-07-10 SK SK26-97A patent/SK2697A3/en unknown
- 1995-07-10 WO PCT/GB1995/001619 patent/WO1996001645A1/en not_active Ceased
- 1995-07-10 CZ CZ9747A patent/CZ4797A3/en unknown
- 1995-07-10 AU AU28935/95A patent/AU2893595A/en not_active Abandoned
- 1995-07-10 CA CA002194678A patent/CA2194678A1/en not_active Abandoned
- 1995-07-10 EP EP95924437A patent/EP0768888A1/en not_active Withdrawn
- 1995-07-10 HU HU9700071A patent/HUT77290A/en unknown
- 1995-07-11 IL IL11454295A patent/IL114542A0/en unknown
- 1995-07-11 ZA ZA955763A patent/ZA955763B/en unknown
-
1997
- 1997-01-10 BG BG101126A patent/BG101126A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU9700071D0 (en) | 1997-02-28 |
| GB9413935D0 (en) | 1994-08-31 |
| IL114542A0 (en) | 1995-11-27 |
| CZ4797A3 (en) | 1997-07-16 |
| HUT77290A (en) | 1998-03-30 |
| CA2194678A1 (en) | 1996-01-25 |
| JPH10505580A (en) | 1998-06-02 |
| EP0768888A1 (en) | 1997-04-23 |
| WO1996001645A1 (en) | 1996-01-25 |
| SK2697A3 (en) | 1997-08-06 |
| AU2893595A (en) | 1996-02-09 |
| ZA955763B (en) | 1997-01-13 |
| CN1155245A (en) | 1997-07-23 |
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